Wenbin Mao
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View article: 3D velocity and pressure field reconstruction in the cardiac left ventricle via physics informed neural network from echocardiography guided by 3D color Doppler
3D velocity and pressure field reconstruction in the cardiac left ventricle via physics informed neural network from echocardiography guided by 3D color Doppler Open
Fluid dynamics of the heart chamber can provide critical biological cues for understanding cardiac health and disease and have the potential for supporting diagnosis and prognosis. However, directly acquiring fluid dynamics information fro…
View article: Hydraconv: A Novel Graph Neural Network for Finite Element Emulation in Biomechanical Modeling
Hydraconv: A Novel Graph Neural Network for Finite Element Emulation in Biomechanical Modeling Open
View article: The Polishing of Inner Wall on Medical Device Hole by Shear Thickening Abrasive Flow
The Polishing of Inner Wall on Medical Device Hole by Shear Thickening Abrasive Flow Open
To improve medical device hole inner wall quality and overcome issues of traditional abrasive flow methods—limited fluidity in small holes causing deformation due to high inner wall pressure, and slow processing with low viscosity abrasive…
View article: A fast approach to estimating Windkessel model parameters for patient-specific multi-scale CFD simulations of aortic flow
A fast approach to estimating Windkessel model parameters for patient-specific multi-scale CFD simulations of aortic flow Open
View article: A Deep Learning Model for the Identification of Active Contraction Properties of the Myocardium Using Limited Clinical Metrics
A Deep Learning Model for the Identification of Active Contraction Properties of the Myocardium Using Limited Clinical Metrics Open
Technological breakthroughs have enhanced our understanding of myocardial mechanics and physiological responses to detect early disease indicators. Using constitutive models to represent myocardium structure is critical for understanding t…
View article: A fast approach to estimating Windkessel model parameters for patient-specific multi-scale CFD simulations of aortic flow
A fast approach to estimating Windkessel model parameters for patient-specific multi-scale CFD simulations of aortic flow Open
Hemodynamics in the aorta from computational fluid dynamics (CFD) simulations can provide a comprehensive analysis of relevant cardiovascular diseases. Coupling the three-element Windkessel model with the patient-specific CFD simulation to…
View article: Design and preparation of a novel colon-targeted tablet of hydrocortisone
Design and preparation of a novel colon-targeted tablet of hydrocortisone Open
The objective of this research was to design a new colon-targeted drug delivery system based on chitosan. The properties of the films were studied to obtain useful information about the possible applications of composite films. The composi…
View article: Patient-specific analysis of bicuspid aortic valve hemodynamics using a fully coupled fluid-structure interaction (FSI) model
Patient-specific analysis of bicuspid aortic valve hemodynamics using a fully coupled fluid-structure interaction (FSI) model Open
Bicuspid aortic valve (BAV), the most common congenital heart disease, is prone to develop significant valvular dysfunction and aortic wall abnormalities. Growing evidence has suggested that abnormal BAV hemodynamics could contribute to th…
View article: Fluid–Structure Interaction Analyses of Biological Systems Using Smoothed-Particle Hydrodynamics
Fluid–Structure Interaction Analyses of Biological Systems Using Smoothed-Particle Hydrodynamics Open
Due to the inherent complexity of biological applications that more often than not include fluids and structures interacting together, the development of computational fluid–structure interaction models is necessary to achieve a quantitati…
View article: Design and preparation of a novel colon-targeted tablet of hydrocortisone
Design and preparation of a novel colon-targeted tablet of hydrocortisone Open
The objective of this research was to design a new colon-targeted drug delivery system based on chitosan. The properties of the films were studied to obtain useful information about the possible applications of composite films. The composi…
View article: Determination of the Solubility, Dissolution Enthalpy, and Entropy of Icariin in Acetone, Acetoacetate, Chloroform, and Light Petroleum
Determination of the Solubility, Dissolution Enthalpy, and Entropy of Icariin in Acetone, Acetoacetate, Chloroform, and Light Petroleum Open
The solubility of icariin in acetone, acetoacetate, chloroform, and light petroleum in the 283.2‐318.2 K range was measured by ultraviolet-visible spectrophotometry. As the temperature increased, the solubility of icariin in the 4 solvents…
View article: The role of stress concentration in calcified bicuspid aortic valve
The role of stress concentration in calcified bicuspid aortic valve Open
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in the aging population, and is now believed to be a slow, progressive, yet actively regulated process. The disease progression can be divided into two phases: …
View article: A Comprehensive Engineering Analysis of Left Heart Dynamics After MitraClip in a Functional Mitral Regurgitation Patient
A Comprehensive Engineering Analysis of Left Heart Dynamics After MitraClip in a Functional Mitral Regurgitation Patient Open
Percutaneous edge-to-edge mitral valve (MV) repair using MitraClip has been recently established as a treatment option for patients with heart failure and functional mitral regurgitation (MR), which significantly expands the number of pati…
View article: The Impact of Self-Expandable Transcatheter Aortic Valve Replacement on Concomitant Functional Mitral Regurgitation: A Comprehensive Engineering Analysis
The Impact of Self-Expandable Transcatheter Aortic Valve Replacement on Concomitant Functional Mitral Regurgitation: A Comprehensive Engineering Analysis Open
View article: Comparative quantification of primary mitral regurgitation by computer modeling and simulated echocardiography
Comparative quantification of primary mitral regurgitation by computer modeling and simulated echocardiography Open
Clinical investigations have demonstrated that mitral regurgitation (MR) quantification using echocardiography (echo) may significantly underestimate or overestimate the regurgitant volume, especially for two-dimensional (2D) echo. Compute…
View article: The impact of balloon-expandable transcatheter aortic valve replacement on concomitant mitral regurgitation: a comprehensive computational analysis
The impact of balloon-expandable transcatheter aortic valve replacement on concomitant mitral regurgitation: a comprehensive computational analysis Open
The aortic and mitral valves function in a reciprocal interdependent fashion. However, the impact of transcatheter aortic valve replacement (TAVR) on the aortic–mitral continuity and severity of mitral regurgitation (MR) are poorly underst…
View article: Author Correction: New insights into mitral heart valve prolapse after chordae rupture through fluid–structure interaction computational modeling
Author Correction: New insights into mitral heart valve prolapse after chordae rupture through fluid–structure interaction computational modeling Open
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
View article: Supplementary material from "The impact of balloon-expandable transcatheter aortic valve replacement on concomitant mitral regurgitation: a comprehensive computational analysis"
Supplementary material from "The impact of balloon-expandable transcatheter aortic valve replacement on concomitant mitral regurgitation: a comprehensive computational analysis" Open
The aortic and mitral valves function in a reciprocal interdependent fashion. However, the impact of transcatheter aortic valve replacement (TAVR) on the aortic-mitral continuity and severity of mitral regurgitation (MR) are poorly underst…
View article: New insights into mitral heart valve prolapse after chordae rupture through fluid–structure interaction computational modeling
New insights into mitral heart valve prolapse after chordae rupture through fluid–structure interaction computational modeling Open
View article: Numerical Parametric Study of Paravalvular Leak Following a Transcatheter Aortic Valve Deployment Into a Patient-Specific Aortic Root
Numerical Parametric Study of Paravalvular Leak Following a Transcatheter Aortic Valve Deployment Into a Patient-Specific Aortic Root Open
Paravalvular leak (PVL) is a relatively frequent complication after transcatheter aortic valve replacement (TAVR) with increased mortality. Currently, there is no effective method to pre-operatively predict and prevent PVL. In this study, …
View article: Simulated Transcatheter Aortic Valve Flow: Implications of Elliptical Deployment and Under‐Expansion at the Aortic Annulus
Simulated Transcatheter Aortic Valve Flow: Implications of Elliptical Deployment and Under‐Expansion at the Aortic Annulus Open
Clinical use of transcatheter aortic valves (TAVs) has been associated with abnormal deployment, including oval deployment and under‐expansion when placed into calcified aortic annuli. In this study, we performed an integrated computationa…
View article: Fully-coupled fluid-structure interaction simulation of the aortic and mitral valves in a realistic 3D left ventricle model
Fully-coupled fluid-structure interaction simulation of the aortic and mitral valves in a realistic 3D left ventricle model Open
In this study, we present a fully-coupled fluid-structure interaction (FSI) framework that combines smoothed particle hydrodynamics (SPH) and nonlinear finite element (FE) method to investigate the coupled aortic and mitral valves structur…
View article: Modeling Left Ventricular Blood Flow Using Smoothed Particle Hydrodynamics
Modeling Left Ventricular Blood Flow Using Smoothed Particle Hydrodynamics Open
View article: Design and preparation of a novel colon-targeted tablet of hydrocortisone
Design and preparation of a novel colon-targeted tablet of hydrocortisone Open
The objective of this research was to design a new colon-targeted drug delivery system based on chitosan. The properties of the films were studied to obtain useful information about the possible applications of composite films. The composi…
View article: Fluid–Structure Interaction Study of Transcatheter Aortic Valve Dynamics Using Smoothed Particle Hydrodynamics
Fluid–Structure Interaction Study of Transcatheter Aortic Valve Dynamics Using Smoothed Particle Hydrodynamics Open
View article: Design and preparation of a novel colon-targeted tablet of hydrocortisone
Design and preparation of a novel colon-targeted tablet of hydrocortisone Open
The objective of this research was to design a new colon-targeted drug delivery system based on chitosan. The properties of the films were studied to obtain useful information about the possible applications of composite films. The composi…
View article: Development of an In Vitro Model to Characterize the Effects of Transcatheter Aortic Valve on Coronary Artery Flow
Development of an In Vitro Model to Characterize the Effects of Transcatheter Aortic Valve on Coronary Artery Flow Open
Impairment of coronary artery flow, in either acute or chronic conditions, is a severe complication of transcatheter aortic valve ( TAV ) implantation, which can arise due to improper TAV positioning. However, little work has been done to …
View article: Eyelashes divert airflow to protect the eye
Eyelashes divert airflow to protect the eye Open
Eyelashes are ubiquitous, although their function has long remained a mystery. In this study, we elucidate the aerodynamic benefits of eyelashes. Through anatomical measurements, we find that 22 species of mammals possess eyelashes of a le…