Wei Wang
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View article: Prognostic value of an abnormal chest X-ray result in predicting the development of tuberculosis
Prognostic value of an abnormal chest X-ray result in predicting the development of tuberculosis Open
Although tuberculosis is preventable, whom to prioritize for preventive interventions is debated. As part of a follow-up to a mass tuberculosis screening, we aimed to evaluate tuberculosis incidence among persons with distinct baseline X-r…
View article: Proteome atlas for mechanistic discovery and risk prediction of diabetic retinopathy
Proteome atlas for mechanistic discovery and risk prediction of diabetic retinopathy Open
View article: Progress in the clinical application of allogeneic platelet-rich plasma for diabetic foot treatment
Progress in the clinical application of allogeneic platelet-rich plasma for diabetic foot treatment Open
Due to peripheral neuropathy and varying degrees of vascular disease, patients with diabetes often suffer from foot ulcers that are challenging to heal and may even progress to gangrene. In recent years, autologous platelet rich plasma (au…
View article: One-year outcomes of trabeculectomy with mitomycin C in secondary glaucoma due to posner-schlossman syndrome
One-year outcomes of trabeculectomy with mitomycin C in secondary glaucoma due to posner-schlossman syndrome Open
To explore the effectiveness and safety of surgical treatment for patients with Posner-Schlossman syndrome (PSS) accompanied by optic nerve Changes. A retrospective analysis was conducted on 15 cases (15 eyes) of glaucoma secondary to PSS …
View article: Preliminary study on the treatment of acute angle closure glaucoma with high intensity focused ultrasound cycloplasty
Preliminary study on the treatment of acute angle closure glaucoma with high intensity focused ultrasound cycloplasty Open
View article: Construction and evaluation of an emotion-inducing video dataset towards Chinese elderly healthy controls and individuals with mild cognitive impairment
Construction and evaluation of an emotion-inducing video dataset towards Chinese elderly healthy controls and individuals with mild cognitive impairment Open
The online version contains supplementary material available at 10.1007/s11571-025-10318-x.
View article: RHO1-2 meganuclease gene editing targets human P23H rhodopsin-induced retinitis pigmentosa to rejuvenate rods and maintain cones
RHO1-2 meganuclease gene editing targets human P23H rhodopsin-induced retinitis pigmentosa to rejuvenate rods and maintain cones Open
Autosomal dominant retinitis pigmentosa (adRP) is an inherited retinal dystrophy characterized by progressive vision loss and eventual blindness. The P23H mutation (proline to histidine substitution at codon 23) in the rhodopsin (RHO) gene…
View article: Patterns and predictors of post-traumatic growth and fear of disease progression in breast cancer patients: a latent profile analysis
Patterns and predictors of post-traumatic growth and fear of disease progression in breast cancer patients: a latent profile analysis Open
Purpose The primary aim of this study is to explore distinct patterns of post-traumatic growth (PTG) and fear of cancer progression (FOP) among breast cancer patients through latent profile analysis (LPA). Additionally, we assessed the dif…
View article: Efficacy and Safety of Efdamrofusp Alfa with Personalized Dosing Intervals in Neovascular Age-Related Macular Degeneration: A Phase II Trial
Efficacy and Safety of Efdamrofusp Alfa with Personalized Dosing Intervals in Neovascular Age-Related Macular Degeneration: A Phase II Trial Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
View article: Integrated CT-derived radiomics for predicting ctDNA status and prognosis in resectable non-small cell lung cancer
Integrated CT-derived radiomics for predicting ctDNA status and prognosis in resectable non-small cell lung cancer Open
This study aimed to develop a radiomics signature for predicting ctDNA status and recurrence risk in non-small cell lung cancer (NSCLC) patients. A retrospective analysis of 631 patients was conducted, with 114 in the training set, 349 in …
View article: Retinal degenerative diseases: Complement system-microglia crosstalk
Retinal degenerative diseases: Complement system-microglia crosstalk Open
Retinal degenerative diseases (RDD) are a group of age-related blinding eye diseases characterized by progressive degeneration and functional impairment of retinal photoreceptors or ganglion cells, for which there are currently no effectiv…
View article: Diagnostic models for sepsis-associated encephalopathy: a comprehensive systematic review and meta-analysis
Diagnostic models for sepsis-associated encephalopathy: a comprehensive systematic review and meta-analysis Open
Objective To systematically evaluate the performance and methodological rigor of published prediction models for sepsis-associated encephalopathy (SAE), identify their limitations, and provide guidance for the future development of robust …
View article: Changes in choriocapillaris blood flow density and associated factors affecting axial elongation in Chinese children and adolescents with mild to moderate myopia: a cross-sectional study
Changes in choriocapillaris blood flow density and associated factors affecting axial elongation in Chinese children and adolescents with mild to moderate myopia: a cross-sectional study Open
View article: Assessing post-marketing safety of PDE5Is in erectile dysfunction: real-world evidence from the FDA adverse event reporting system
Assessing post-marketing safety of PDE5Is in erectile dysfunction: real-world evidence from the FDA adverse event reporting system Open
Erectile dysfunction (ED) is a common condition affecting men worldwide. The U.S. Food and Drug Administration (FDA) has approved phosphodiesterase type 5 inhibitors (PDE5Is), including sildenafil, tadalafil, vardenafil, and avanafil, for …
View article: Global, regional, and national trends in the epidemiology of aortic aneurysms among women of childbearing age, 1990–2021, with predictions through 2036
Global, regional, and national trends in the epidemiology of aortic aneurysms among women of childbearing age, 1990–2021, with predictions through 2036 Open
Although the global burden of AA among women of childbearing age is decreasing, significant regional disparities persist, and the rising prevalence of hypertension and high BMI poses ongoing challenges. Strengthened prevention strategies t…
View article: Predicting hemorrhage expansion in patients with hypertensive intracerebral hemorrhage: the HE-VSD-A2TP score
Predicting hemorrhage expansion in patients with hypertensive intracerebral hemorrhage: the HE-VSD-A2TP score Open
Background Hematoma expansion (HE) in hypertensive intracerebral hemorrhage (HICH) is significantly associated with patient mortality. Early identification of HE would be planning for appropriate and aggressive management for improving out…
View article: Metabolic regulation of visual acuity
Metabolic regulation of visual acuity Open
Photoreceptors signal ON and OFF pathways via a synapse with bipolar cells that are transmitted to retinal ganglion cells (RGCs) for luminance and contrast detection. Retinal neurons metabolize glucose whose transport is mediated by photor…
View article: Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p
Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p Open
Background Circular RNAs (circRNAs) regulate gene expression by functioning as competing endogenous RNAs (ceRNAs) and are increasingly recognized for their involvement in cancer progression. Hsa_circ_0018909 is upregulated in non-small cel…
View article: Causality of genetically determined gut microbiota on lung cancer: a Mendelian randomization study
Causality of genetically determined gut microbiota on lung cancer: a Mendelian randomization study Open
These findings suggest that targeting gut microbiota-associated pathways, such as short-chain fatty acid (SCFA) production, may offer novel strategies for LC prevention and treatment. Future research should explore the clinical implication…
View article: Metabolic and immune heterogeneity in stroke: Insights into subtype identification and biomarker discovery
Metabolic and immune heterogeneity in stroke: Insights into subtype identification and biomarker discovery Open
Stroke is a leading cause of mortality and long-term disability worldwide, characterized by substantial molecular and clinical heterogeneity. This study aimed to investigate the metabolic and immune-related mechanisms underlying stroke sub…
View article: Longitudinal Changes in Macular Vessel Density in High Myopia on Optical Coherence Tomography Angiography
Longitudinal Changes in Macular Vessel Density in High Myopia on Optical Coherence Tomography Angiography Open
Introduction: The aim of the study was to quantitatively characterize the longitudinal changes in macular vessel density (VD) in eyes with high myopia using swept source-optical coherence tomography angiography (SS-OCTA). Methods: A total …
View article: The impact of soft contact lenses on the corneal neuromediators and optical quality in high myopia
The impact of soft contact lenses on the corneal neuromediators and optical quality in high myopia Open
The prolonged wear of SCLs in individuals with high myopia may result in an increase in the levels of corneal stromal neuromediators and a deterioration in corneal optical quality. Notably, neuromediators are significantly associated with …
View article: Prevalence, incidence, and risk factors of diabetic retinopathy and macular edema in patients with early and late‐onset type 2 diabetes mellitus
Prevalence, incidence, and risk factors of diabetic retinopathy and macular edema in patients with early and late‐onset type 2 diabetes mellitus Open
Aims To compare the prevalence, incidence, and factors of diabetic retinopathy (DR) and macular edema (DME) in patients with early‐onset (EOD) and late‐onset diabetes (LOD). Methods Participants with type 2 diabetes mellitus (T2DM) were re…
View article: Antiarrhythmic Drug Use in the Blanking Period After Re‐Ablation and Recurrence in Paroxysmal Atrial Fibrillation
Antiarrhythmic Drug Use in the Blanking Period After Re‐Ablation and Recurrence in Paroxysmal Atrial Fibrillation Open
Background The effectiveness of continuous anti‐arrhythmic drugs (AAD) therapy during the 3‐month blanking period following repeat catheter ablation to prevent atrial fibrillation (AF) recurrence remains unclear. To evaluate the impact of …
View article: Evaluating the predictive value of log odds of positive lymph nodes on postoperative survival in patients with laryngeal cancer: a SEER population-based study
Evaluating the predictive value of log odds of positive lymph nodes on postoperative survival in patients with laryngeal cancer: a SEER population-based study Open
Traditionally, the AJCC TNM staging system has been the primary tool for assessing the severity and prognosis of laryngeal cancer. Although several studies have demonstrated that the log odds of positive lymph nodes (LODDS) offers superior…
View article: Joint effects of sleep behaviors and physical activity on brain structure and cognitive function
Joint effects of sleep behaviors and physical activity on brain structure and cognitive function Open
View article: Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker
Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker Open
Plasma proteomic analysis reveals that high expression of SVEP1 is a risk factor for exfoliation glaucoma, which potentially affects diabetes and is affected by estradiol or LOXL1-AS1. However, further research is needed to establish causa…
View article: Healthy lifestyle habits, educational attainment, and the risk of 45 age-related health and mortality outcomes in the UK: A prospective cohort study
Healthy lifestyle habits, educational attainment, and the risk of 45 age-related health and mortality outcomes in the UK: A prospective cohort study Open
View article: Changes in peripapillary microvasculature and retinal nerve fibre layer in diabetes and diabetic retinopathy using optical coherence tomographic angiography: a community-based, cross-sectional study
Changes in peripapillary microvasculature and retinal nerve fibre layer in diabetes and diabetic retinopathy using optical coherence tomographic angiography: a community-based, cross-sectional study Open
Objective To evaluate changes in the peripapillary retinal microvasculature and retinal nerve fibre layer (RNFL) in diabetic participants with various stages of diabetic retinopathy (DR) using swept-source optical coherence tomographic ang…
View article: Citrate as a safe and effective alternative to heparin for catheter locking: a systematic review and meta-analysis of randomized controlled trials
Citrate as a safe and effective alternative to heparin for catheter locking: a systematic review and meta-analysis of randomized controlled trials Open
Background Consensus on the use of citrate vs.heparin for catheter locking remains elusive, with ongoing controversy. This meta-analysis investigates the efficacy and safety of citrate lock solutions compared to heparin lock solutions in p…