Explanipedia

B-342 Ex-Vivo Evaluation of the MasSpec Pen Technology for Hepatocellular Carcinoma Margin Assessment Open

Trevor M. Godfrey, Belkacem Acidi, Pearl Fernandes, Sarah Bench, Amalia Castelli González , et al. · 2025

Introduction Hepatocellular carcinoma (HCC) is a prevalent cancer that causes an estimated 781,000 deaths/year. Complete surgical resection of HCC is considered first-line treatment for patients with localized disease and is critical for l…

Utility of whole‐slide imaging for rapid evaluation of thyroid FNA: A multireader prospective study Open

Mohammed S. Ahmed, Dianna Klippel‐Almaraz, Sara E. Amin, Gloria H. Sura, Uma Kundu , et al. · 2025

Background Rapid on‐site evaluation (ROSE) of thyroid fine‐needle aspiration biopsy (FNAB) improves diagnostic adequacy and facilitates ancillary molecular testing. In this prospective, multireader study, the authors evaluated the feasibil…

Intraoperative Identification of Thyroid and Parathyroid Tissues During Human Endocrine Surgery Using the MasSpec Pen Open

Rachel J. DeHoog, Mary Etta King, Michael F. Keating, Jialing Zhang, Marta Sans , et al. · 2023

Importance Intraoperative identification of tissues through gross inspection during thyroid and parathyroid surgery is challenging yet essential for preserving healthy tissue and improving outcomes for patients. Objective To evaluate the p…

The Yokohama System for Reporting Breast Cytopathology Open

Wendong Yu, Qiong Gan, Yun Yun Gong · 2023

The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytology was developed by a group of expert cytopathologists and clinicians in the breast field. Five categories are defined to strati…

Data from Targeting Fibroblast Growth Factor Receptor Signaling Inhibits Prostate Cancer Progression Open

Shu Feng, Longjiang Shao, Wendong Yu, Paul R. Gavine, Michael Ittmann · 2023

Purpose: Extensive correlative studies in human prostate cancer as well as studies in vitro and in mouse models indicate that fibroblast growth factor receptor (FGFR) signaling plays an important role in prostate cancer progr…

Supplemental Figures and Tables from Cardiolipins Are Biomarkers of Mitochondria-Rich Thyroid Oncocytic Tumors Open

Jialing Zhang, Wendong Yu, Seung Woo Ryu, John C. Lin, Gerardo Buentello , et al. · 2023

This supplemental file contains data that supports the claims and results described in the main manuscript. Figures include full mass spectra data acquired for the representative thyroid samples, examples of fragmentation patterns obtained…

Supplementary Data from Mass Spectrometry Imaging Enables Discrimination of Renal Oncocytoma from Renal Cell Cancer Subtypes and Normal Kidney Tissues Open

Jialing Zhang, Shirley Q. Li, John Q. Lin, Wendong Yu, Lívia S. Eberlin · 2023

Supplementary Figures and Supplementary Figure legends. Supplementary Fig. 1.- Tandem mass spectrum of m/z 810.527 and the tentative assignment, Supplementary Fig. 2.- Tandem mass spectrum of m/z 723.478 and the tentative assignment, Suppl…

Supplementary Figure 1 from Targeting Fibroblast Growth Factor Receptor Signaling Inhibits Prostate Cancer Progression Open

Shu Feng, Longjiang Shao, Wendong Yu, Paul R. Gavine, Michael Ittmann · 2023

PDF file, 188KB, AZ8010 inhibits VCaP proliferation and increases apoptosis.

Supplementary Figure Legend from Targeting Fibroblast Growth Factor Receptor Signaling Inhibits Prostate Cancer Progression Open

Shu Feng, Longjiang Shao, Wendong Yu, Paul R. Gavine, Michael Ittmann · 2023

PDF file, 60KB.

Data from Cardiolipins Are Biomarkers of Mitochondria-Rich Thyroid Oncocytic Tumors Open

Jialing Zhang, Wendong Yu, Seung Woo Ryu, John C. Lin, Gerardo Buentello , et al. · 2023

Oncocytic tumors are characterized by an excessive eosinophilic, granular cytoplasm due to aberrant accumulation of mitochondria. Mutations in mitochondrial DNA occur in oncocytic thyroid tumors, but there is no information about their lip…

Supplementary Figure 2 from Targeting Fibroblast Growth Factor Receptor Signaling Inhibits Prostate Cancer Progression Open

Shu Feng, Longjiang Shao, Wendong Yu, Paul R. Gavine, Michael Ittmann · 2023

PDF file, 223KB, Ki67 and CD31 immunohistochemistry and TUNEL of VCaP tumors from mice treated with AZ8010 or vehicle only.

Data from Cardiolipins Are Biomarkers of Mitochondria-Rich Thyroid Oncocytic Tumors Open

Jialing Zhang, Wendong Yu, Seung Woo Ryu, John C. Lin, Gerardo Buentello , et al. · 2023

Oncocytic tumors are characterized by an excessive eosinophilic, granular cytoplasm due to aberrant accumulation of mitochondria. Mutations in mitochondrial DNA occur in oncocytic thyroid tumors, but there is no information about their lip…

Supplementary Figure 3 from Targeting Fibroblast Growth Factor Receptor Signaling Inhibits Prostate Cancer Progression Open

Shu Feng, Longjiang Shao, Wendong Yu, Paul R. Gavine, Michael Ittmann · 2023

PDF file, 954KB, Treatment with AZ8010 does not inhibit AKT phosphorylation.

Supplemental Materials and Methods from Cardiolipins Are Biomarkers of Mitochondria-Rich Thyroid Oncocytic Tumors Open

Jialing Zhang, Wendong Yu, Seung Woo Ryu, John C. Lin, Gerardo Buentello , et al. · 2023

This supplemental file contains detailed descriptions of the methods employed in the research reported in the main manuscript, including the methods used for molecular imaging experiments using DESI-MS, immunohistochemistry and immunofluor…

Data from Mass Spectrometry Imaging Enables Discrimination of Renal Oncocytoma from Renal Cell Cancer Subtypes and Normal Kidney Tissues Open

Jialing Zhang, Shirley Q. Li, John Q. Lin, Wendong Yu, Lívia S. Eberlin · 2023

Precise diagnosis and subtyping of kidney tumors are imperative to optimize and personalize treatment decision for patients. Patients with the most common benign renal tumor, renal oncocytomas, may be overtreated with surgical resection be…