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View article: Impact of Aortic Annulus Angulation on the Outcomes of Transcatheter Aortic Valve Replacement in Bicuspid Anatomy
Impact of Aortic Annulus Angulation on the Outcomes of Transcatheter Aortic Valve Replacement in Bicuspid Anatomy Open
Objective: This study aimed to explore the impact of aortic annulus angulation on outcomes in patients with bicuspid aortic valves (BAVs) undergoing transcatheter aortic valve replacement (TAVR) with new-generation valves. Methods: A retro…
View article: Impact of DHEA supplementation on testosterone and estradiol levels in postmenopausal women: a meta-analysis of randomized controlled trials assessing dose and duration effects
Impact of DHEA supplementation on testosterone and estradiol levels in postmenopausal women: a meta-analysis of randomized controlled trials assessing dose and duration effects Open
DHEA supplementation at doses ≥ 50 mg/day significantly increases testosterone levels in postmenopausal women. Moreover, in women aged ≥ 60 years, supplementation at the same dosage significantly elevates estradiol levels.
View article: Nano hydroxyapatite: preparation, characterization and anti-tumor activity evaluation
Nano hydroxyapatite: preparation, characterization and anti-tumor activity evaluation Open
The nano-hydroxyapatite (nHAp) displayed significant superiority in drug delivery and antitumor fields, which has attracted widespread attention. However, the insufficient study on the anti-tumor activity and safety restricted its applicat…
View article: Comparison of Heart Rate Variability in People With Diabetes‐Related Neuropathic Foot to Their Counterparts Without a Foot Ulcer History: A Propensity Score Matching Study
Comparison of Heart Rate Variability in People With Diabetes‐Related Neuropathic Foot to Their Counterparts Without a Foot Ulcer History: A Propensity Score Matching Study Open
Background: The reasons that individuals with diabetic foot ulceration (DFU) have higher cardiovascular mortality than those with Type 2 diabetes mellitus (T2DM) but without DFU remain controversial. We aimed to compare the differences in …
View article: Study of thermal and humidity properties of SiO 2 aerogel composites with porous media
Study of thermal and humidity properties of SiO 2 aerogel composites with porous media Open
Building insulation improves the thermal environment of a building and significantly reduces energy consumption for heating and air conditioning. Traditional insulation materials are prone to moisture absorption and a significant reduction…
View article: Adaptive Caching for Faster Video Generation with Diffusion Transformers
Adaptive Caching for Faster Video Generation with Diffusion Transformers Open
Generating temporally-consistent high-fidelity videos can be computationally expensive, especially over longer temporal spans. More-recent Diffusion Transformers (DiTs) -- despite making significant headway in this context -- have only hei…
View article: O035 Refining the desaturation area-based parameters by investigating different baseline methods
O035 Refining the desaturation area-based parameters by investigating different baseline methods Open
Introduction Repetitive hypoxia serves as the principal mechanistic bridge between Obstructive Sleep Apnoea and cardiovascular disease (CVD). Desaturation area-based parameters, like Hypoxic Burden (HB) and the Respiratory Event Desaturati…
View article: P22.04.B BALANCING COMMUNICATION CHALLENGES IN NEURO-ONCOLOGY: A CROSS-SECTIONAL INTERVIEW STUDY WITH NEURO-ONCOLOGY HEALTHCARE PROFESSIONALS
P22.04.B BALANCING COMMUNICATION CHALLENGES IN NEURO-ONCOLOGY: A CROSS-SECTIONAL INTERVIEW STUDY WITH NEURO-ONCOLOGY HEALTHCARE PROFESSIONALS Open
BACKGROUND Primary brain tumours are associated with a significant symptom burden and high supportive care needs, presenting in varied and unique ways along the disease trajectory. Timely and comprehensive patient navigation is vital to en…
View article: OS02.6.A COORDINATION OF CARE IN THE CONTEXT OF PRIMARY BRAIN TUMOURS: HEALTHCARE PROFESSIONALS’ EXPLORATION OF THE UNSPOKEN IMPACT AND CLINICAL IMPLICATIONS
OS02.6.A COORDINATION OF CARE IN THE CONTEXT OF PRIMARY BRAIN TUMOURS: HEALTHCARE PROFESSIONALS’ EXPLORATION OF THE UNSPOKEN IMPACT AND CLINICAL IMPLICATIONS Open
BACKGROUND People with primary brain tumours (PwBT) and their families expereince high distress and face challenges navigating the disease, healthcare system, treatment, and/or survivorship. Coordination of care is an approach to achieving…
View article: Cardiac electrophysiology, structure and diastolic function in patients with diabetic foot versus those without diabetic foot
Cardiac electrophysiology, structure and diastolic function in patients with diabetic foot versus those without diabetic foot Open
Aims/Introduction To evaluate the differences in cardiac autonomic function, cardiac structure and diastolic function between individuals with diabetic foot (DF) and those with diabetes but without DF. Materials and Methods A total of 413 …
View article: The effects of initial and subsequent overweight or obesity on hypertension in the middle age
The effects of initial and subsequent overweight or obesity on hypertension in the middle age Open
The aims of our study were to examine whether initial or subsequent adiposity status had a greater effect on hypertension. We collected data in 1992 and again in 2007 from the same group of 597 individuals in the middle age. The subjects w…
View article: Prognostic Analysis and an Appropriate Antiplatelet Strategy for Patients With Percutaneous Coronary Intervention and High Bleeding Risk: Rationale and Protocol for a Multi-Center Cohort Study
Prognostic Analysis and an Appropriate Antiplatelet Strategy for Patients With Percutaneous Coronary Intervention and High Bleeding Risk: Rationale and Protocol for a Multi-Center Cohort Study Open
Percutaneous coronary intervention (PCI) is an important treatment strategy for patients with coronary artery disease. However, bleeding after PCI significantly increases the mortality risk. The search for prognostic predictors and optimal…
View article: O008 Refining the Hypoxic Burden Algorithm by Investigating different Methods for Calculating the SpO2 Baseline
O008 Refining the Hypoxic Burden Algorithm by Investigating different Methods for Calculating the SpO2 Baseline Open
Introduction Intermittent hypoxia is a key mechanism linking Obstructive Sleep Apnoea (OSA) to cardiovascular disease (CVD). Oximetry analysis could enhance understanding of which OSA phenotypes are associated with CVD risk. The hypoxic bu…
View article: P038 Characterising Pulse Wave Amplitude Drops in Patients with Acute Coronary Syndrome
P038 Characterising Pulse Wave Amplitude Drops in Patients with Acute Coronary Syndrome Open
Pulse wave amplitude derived from photoplethysmography signals is a surrogate measure of autonomic function and vascular response. Recent studies have demonstrated low pulse wave amplitude drop(PWAD) index to be associated with increased c…
View article: Assessing the relationship between monocyte-to-HDL cholesterol ratio and mortality in patients with hypertrophic cardiomyopathy
Assessing the relationship between monocyte-to-HDL cholesterol ratio and mortality in patients with hypertrophic cardiomyopathy Open
In Chinese adult patients with HCM, higher MHR is a strong independent predictor of ACM, and a non-linear relationship is also observed between MHR and ACM.
View article: Rationale and design of a multi‐center, prospective randomized controlled trial on the effects of sacubitril–valsartan versus enalapril on left ventricular remodeling in <scp>ST</scp>‐elevation myocardial infarction: The <scp>PERI‐STEMI</scp> study
Rationale and design of a multi‐center, prospective randomized controlled trial on the effects of sacubitril–valsartan versus enalapril on left ventricular remodeling in <span>ST</span>‐elevation myocardial infarction: The <span>PERI‐STEMI</span> study Open
Background Angiotensin receptor neprilysin inhibitor (ARNI) sacubitril‐valsartan has been recommended as one of the first‐line therapies in heart failure with reduced ejection fraction. However, whether ARNI could benefit patients with ST‐…
View article: A fenestrated persistent primitive hypoglossal artery harboring a ruptured aneurysm
A fenestrated persistent primitive hypoglossal artery harboring a ruptured aneurysm Open
Rationale: Persistent primitive hypoglossal artery (PPHA) is a rare and permanent carotid-vertebrobasilar anastomoses. Patients with PPHA usually have higher changes of developing intracranial aneurysms due the high intracranial hemodynami…
View article: Rationale and design of the <scp>OPTIMAL‐REPERFUSION</scp> trial: A prospective randomized multi‐center clinical trial comparing different fibrinolysis‐transfer percutaneous coronary intervention strategies in acute <scp>ST</scp>‐segment elevation myocardial infarction
Rationale and design of the <span>OPTIMAL‐REPERFUSION</span> trial: A prospective randomized multi‐center clinical trial comparing different fibrinolysis‐transfer percutaneous coronary intervention strategies in acute <span>ST</span>‐segment elevation myocardial infarction Open
Primary percutaneous coronary intervention (PPCI), the preferred reperfusion strategy for all acute ST‐segment elevation myocardial infarction (STEMI) patients, is not universally available in clinical practice. Pharmacoinvasive strategy h…
View article: Correlation between Serum 25(OH)D and Abdominal Visceral Fat Area in Patients with Type 2 Diabetes Mellitus in the Context of Different Bone Mass
Correlation between Serum 25(OH)D and Abdominal Visceral Fat Area in Patients with Type 2 Diabetes Mellitus in the Context of Different Bone Mass Open
Serum 25(OH)D and VFA may be associated with the development of T2DM combined with OP.