Wenfeng Zhu
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View article: <scp>KYNA</scp> Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via <scp>FTO</scp>‐Dependent <scp>m6A</scp> Demethylation of <scp>LATS1</scp>
<span>KYNA</span> Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via <span>FTO</span>‐Dependent <span>m6A</span> Demethylation of <span>LATS1</span> Open
Hepatic ischemia–reperfusion injury (HIRI) substantially influences the prognosis of liver transplant recipients. Although kynurenic acid (KYNA) has been associated with protective effects against ischemia–reperfusion injury in various org…
View article: Comment on: Atezolizumab plus bevacizumab in unresectable HCC: insights from the AMETHISTA trial interim analysis
Comment on: Atezolizumab plus bevacizumab in unresectable HCC: insights from the AMETHISTA trial interim analysis Open
View article: Development and clinical validation of a novel platelet count-based nomogram for predicting microvascular invasion in HCC
Development and clinical validation of a novel platelet count-based nomogram for predicting microvascular invasion in HCC Open
We aimed to develop a convenient nomogram to predict preoperative MVI in patients with hepatocellular carcinoma (HCC). Patients who underwent surgical resection due to HCC from June 2018 to June 2023 at the Third Affiliated Hospital of Sun…
View article: Carbon emissions assessment of cement mixing piles for soft loess improvement and carbon emission reduction using white mud-cement composite material
Carbon emissions assessment of cement mixing piles for soft loess improvement and carbon emission reduction using white mud-cement composite material Open
During the highway construction in the soft loess region of Northwestern China, there are always tens of thousands of cement mixing piles were used. Which generates a large amount of carbon emissions, thereby affecting the environment. The…
View article: Effects of Heating Bituminous Mixtures in a Hot-Gas Drum Based on a Finite Volume Method
Effects of Heating Bituminous Mixtures in a Hot-Gas Drum Based on a Finite Volume Method Open
Hot-gas drum heating (HDH) of bituminous mixtures is a new approach to heating bituminous mixtures that is influenced by the parameters of the hot gas and drum. A fluid thermal numerical model was developed to evaluate the effects of heati…
View article: Small-strain characterization of Shanghai clays by triaxial compression tests
Small-strain characterization of Shanghai clays by triaxial compression tests Open
The mechanical properties of the upper Shanghai Layers 2-6 clays at small strain levels have been extensively investigated. Nonetheless, limited data exist on their small-strain characteristics through K 0 -consolidated undrained triaxial …
View article: Diagnostic performance of PIVKA-II in identifying recurrent hepatocellular carcinoma following curative resection: a retrospective cohort study
Diagnostic performance of PIVKA-II in identifying recurrent hepatocellular carcinoma following curative resection: a retrospective cohort study Open
View article: JNK signaling mediates acute rejection via activating autophagy of CD8+ T cells after liver transplantation in rats
JNK signaling mediates acute rejection via activating autophagy of CD8+ T cells after liver transplantation in rats Open
Background Acute rejection (AR) after liver transplantation (LT) remains an important factor affecting the prognosis of patients. CD8 + T cells are considered to be important regulatory T lymphocytes involved in AR after LT. Our previous s…
View article: Modeling and Predicting for Low-Temperature Sealing Performance by Multi-Scale Method of Fuel Cell
Modeling and Predicting for Low-Temperature Sealing Performance by Multi-Scale Method of Fuel Cell Open
View article: Comparison of long-term outcomes of splenectomy with periesophagogastric devascularization and transjugular intrahepatic portosystemic shunt in treating cirrhotic portal hypertension patients with recurrent variceal bleeding
Comparison of long-term outcomes of splenectomy with periesophagogastric devascularization and transjugular intrahepatic portosystemic shunt in treating cirrhotic portal hypertension patients with recurrent variceal bleeding Open
View article: Hippo (YAP)–autophagy axis protects against hepatic ischemia-reperfusion injury through JNK signaling
Hippo (YAP)–autophagy axis protects against hepatic ischemia-reperfusion injury through JNK signaling Open
Background: Hepatic ischemia-reperfusion injury (HIRI) remains a common complication during liver transplantation (LT) in patients. As a key downstream effector of the Hippo pathway, Yes-associated protein (YAP) has been reported to be inv…
View article: Application of associating liver partition and portal vein ligation for staged hepatectomy for initially unresectable hepatocellular carcinoma
Application of associating liver partition and portal vein ligation for staged hepatectomy for initially unresectable hepatocellular carcinoma Open
View article: Comparison of Iliac Bone Transplantation with Bone Transport in the Treatment of Femur Fracture and Bone Defect
Comparison of Iliac Bone Transplantation with Bone Transport in the Treatment of Femur Fracture and Bone Defect Open
Objective. To compare the curative effect of iliac bone transplantation with the bone transport in the treatment of femur fracture complicated with a bone defect. Methods. Patients with femur fractures and defects who were admitted to our …
View article: Slope Instability Analysis in Permafrost Regions by Shear Strength Parameters and Numerical Simulation
Slope Instability Analysis in Permafrost Regions by Shear Strength Parameters and Numerical Simulation Open
With the onset of global warming, the environment has profoundly changed. The melting of ice and slope instability were widely observed in the permafrost regions of the Qinghai–Tibet Plateau, which has destroyed infrastructure and threaten…
View article: Simulation Prediction and Forming Quality Control of Hemming Structure with Dissimilar Materials Oriented to Process Chain
Simulation Prediction and Forming Quality Control of Hemming Structure with Dissimilar Materials Oriented to Process Chain Open
Multi-material mixed-use has become an important way to realize autobody lightweight. However, due to the difference of material properties, the structure is prone to material mismatch when using thin and dissimilar materials. In this pape…
View article: Fabrication of Naturally Derived Double-Network Hydrogels With a Sustained Aspirin Release System for Facilitating Bone Regeneration
Fabrication of Naturally Derived Double-Network Hydrogels With a Sustained Aspirin Release System for Facilitating Bone Regeneration Open
Continuous efforts on pursuit of effective drug delivery systems for engineering hydrogel scaffolds is considered a promising strategy for the bone-related diseases. Here, we developed a kind of acetylsalicylic acid (aspirin, ASA)–based do…
View article: Numerical Quantification Model and Experiment of External Force on Roller Hemming of Curved Edge Aluminium Alloy with Adhesive
Numerical Quantification Model and Experiment of External Force on Roller Hemming of Curved Edge Aluminium Alloy with Adhesive Open
Accurate quantification of external force is the key to improve the high-precision hemming of autobody closure panels. However, the mechanism of external force on forming quality of complex contour sheet metal with adhesive is not clear su…
View article: Numerical Simulation Method of Roller Hemming on Variable Curvature Aluminium Alloy Sheet with Adhesive
Numerical Simulation Method of Roller Hemming on Variable Curvature Aluminium Alloy Sheet with Adhesive Open
To realize the roller forming process of curved edges of aluminium alloy auto-body closure panels, a numerical simulation method is proposed for the roller forming of aluminium alloy sheet with adhesive in flat variable curvature. Firstly,…
View article: Hippo (YAP)-Autophagy Axis Protects Against Hepatic Ischemia Reperfusion Injury Through JNK Signalling
Hippo (YAP)-Autophagy Axis Protects Against Hepatic Ischemia Reperfusion Injury Through JNK Signalling Open
View article: Numerical quantification model and experiment of external force on roller hemming of curved edge aluminium alloy with adhesive
Numerical quantification model and experiment of external force on roller hemming of curved edge aluminium alloy with adhesive Open
Accurate quantification of external force is the key to improve the high-precision hemming of autobody closure panels. However, the mechanism of external force on forming quality of complex contour sheet metal with adhesive is not clear su…
View article: Numerical and Experimental Study on Curing-induced Residual Stress and Deformation of Adhesively Bonded Sandwich Structures of Dissimilar Materials
Numerical and Experimental Study on Curing-induced Residual Stress and Deformation of Adhesively Bonded Sandwich Structures of Dissimilar Materials Open
Adhesively bonded sandwich structure with dissimilar materials becomes an important means of lightweight for the next generation of autobody closure panels. However, during the baking process, the complicated change of physical properties …
View article: Numerical simulation and experimental analysis of vibration characteristics of heterogeneous sheet structure with adhesive
Numerical simulation and experimental analysis of vibration characteristics of heterogeneous sheet structure with adhesive Open
The use of steel-aluminum heterogeneous sheets and its adhesive-coated hemming process for cover parts helps to realize the lightweight of the car body, and its vibration characteristics greatly affect the NVH characteristics of the vehicl…
View article: Experimental study of one-part geopolymer using different alkali sources
Experimental study of one-part geopolymer using different alkali sources Open
This paper investigates the feasibility of combining different solid alkali materials as activator to prepare one-part geopolymer mortars. The effects of different composite solid activators on aluminosilicate materials were studied and co…
View article: Numerical Simulation and Experiment of Roller Hemming-compression with Flat Surface-curved Edge Aluminum Alloy Sheet Based on SPH
Numerical Simulation and Experiment of Roller Hemming-compression with Flat Surface-curved Edge Aluminum Alloy Sheet Based on SPH Open
摘要: 滚边压合是实现车身门盖件内外板高质量连接的装配工艺,其成形机理及质量预测一直是关注的重点。为定量揭示胶黏剂对轻质薄板成形的影响机理,引入光滑粒子法(Smoothed particle hydrodynamics,SPH)模拟胶黏剂,建立能满足工程实际的预测模型,并与传统欧拉法(Euler)进行了对比,验证了方法的可行性。以典型曲线轮廓结构为研究对象,采用有限元法(Finite element method,FEM)模拟铝合金薄板,建立SPH-FEM耦合的数值模型,对…
View article: Study on adsorption for Pb2+ of red mud sintering-expanded haydites
Study on adsorption for Pb2+ of red mud sintering-expanded haydites Open