Wenhan Ju
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View article: The hidden driver of osteoporosis: mitochondria-dominated inflammation
The hidden driver of osteoporosis: mitochondria-dominated inflammation Open
Mitochondria are powerful multifunctional intracellular organelles involved in a wide array of cellular processes. Emerging evidence has highlighted mitochondria as pivotal activators of innate immunity and key participants in inflammatory…
View article: SIRT1 mediates KU70 to maintain Genomic Stability in Spermatogonial Stem Cells via NHEJ Repair pathway
SIRT1 mediates KU70 to maintain Genomic Stability in Spermatogonial Stem Cells via NHEJ Repair pathway Open
Background Male infertility is closely related to DNA double-strand breaks in spermatogonial stem cells (SSCs); however, the precise mechanism still remains to be fully elucidated. While SIRT1 is a key regulator of DNA damage response and …
View article: After Ovulation Induction, Women of Childbearing Age Stopped Their Menstruation for 50 days, Was Occured Double Chorionic Biamniotic Sac for Pregnancy in the Interstitial Part of the Tubal: A Case Report
After Ovulation Induction, Women of Childbearing Age Stopped Their Menstruation for 50 days, Was Occured Double Chorionic Biamniotic Sac for Pregnancy in the Interstitial Part of the Tubal: A Case Report Open
Ectopic pregnancy is a dangerous gynecological acute abdomen, its incidence is about 1%-2% of clinical pregnancy, and in the case of assisted reproductive technology intervention, the incidence increased to about twice. The probability of …
View article: Mitochondria-driven inflammation: a new frontier in ovarian ageing
Mitochondria-driven inflammation: a new frontier in ovarian ageing Open
View article: Targeting programmed cell death with natural products: a potential therapeutic strategy for diminished ovarian reserve and fertility preservation
Targeting programmed cell death with natural products: a potential therapeutic strategy for diminished ovarian reserve and fertility preservation Open
The depletion of ovarian reserve is a major factor contributing to the decline in female fertility. It is characterized by a simultaneous reduction in the quantity and quality of oocytes and the follicular pools. The cyclic recruitment of …
View article: Comparative analysis of hCG and dual-trigger protocols in IVF for advanced maternal age women: a single‑center retrospective cohort study based on propensity score matching
Comparative analysis of hCG and dual-trigger protocols in IVF for advanced maternal age women: a single‑center retrospective cohort study based on propensity score matching Open
View article: Ovarian Torsion at 8 weeks of Gestation in a Woman with Threatened Abortion After Frozen-Thawed Embryo Transfer: A Case Report
Ovarian Torsion at 8 weeks of Gestation in a Woman with Threatened Abortion After Frozen-Thawed Embryo Transfer: A Case Report Open
The use of clomiphene citrate during endometrium preparation for frozen-thawed embryo transfer cycles may elevate the risk of ovarian torsion. Laparoscopic ovarian repositioning after ovarian torsion in pregnant women, even those with thre…
View article: Combining single-cell RNA sequencing and network pharmacology to explore the target of cangfu daotan decoction in the treatment of obese polycystic ovary syndrome from an immune perspective
Combining single-cell RNA sequencing and network pharmacology to explore the target of cangfu daotan decoction in the treatment of obese polycystic ovary syndrome from an immune perspective Open
Background Polycystic ovary syndrome (PCOS) is a heterogeneous gynecological endocrine disorder linked to immunity. Cangfu Daotan Decoction (CFDT), a classic Chinese medicine prescription, is particularly effective in treating PCOS, specif…
View article: Mechanisms of mitochondrial dysfunction in ovarian aging and potential interventions
Mechanisms of mitochondrial dysfunction in ovarian aging and potential interventions Open
Mitochondria plays an essential role in regulating cellular metabolic homeostasis, proliferation/differentiation, and cell death. Mitochondrial dysfunction is implicated in many age-related pathologies. Evidence supports that the dysfuncti…
View article: miR-6881-3p contributes to diminished ovarian reserve by regulating granulosa cell apoptosis by targeting SMAD4
miR-6881-3p contributes to diminished ovarian reserve by regulating granulosa cell apoptosis by targeting SMAD4 Open
View article: Cangfu Daotan Wan alleviates polycystic ovary syndrome with phlegm-dampness syndrome via disruption of the PKP3/ERCC1/MAPK axis
Cangfu Daotan Wan alleviates polycystic ovary syndrome with phlegm-dampness syndrome via disruption of the PKP3/ERCC1/MAPK axis Open
View article: Endometrial compaction is associated with the outcome of artificial frozen-thawed embryo transfer cycles: a retrospective cohort study
Endometrial compaction is associated with the outcome of artificial frozen-thawed embryo transfer cycles: a retrospective cohort study Open
Introduction The relationships between the outcome of frozen-thaw embryo transfer (FET) cycle and endometrial compaction were not quite consistent. Objective To analyze the relationship between the outcome of FET cycle and endometrial comp…
View article: Analysis of Relative Importance of Factors Affecting the Chance of Admission of Applying to Graduate Students
Analysis of Relative Importance of Factors Affecting the Chance of Admission of Applying to Graduate Students Open
The conceptualization of statistical model: the initial characteristic of linear regression revealed by Karl Pearson lay the foundation for the exploration of Sir Francis Galton. The article discusses the concept of the linear regression m…
View article: The effect of adding exogenous LH to IVF/ICSI cycles on pregnancy outcomes in elderly women with PCOS: a retrospective cohort study
The effect of adding exogenous LH to IVF/ICSI cycles on pregnancy outcomes in elderly women with PCOS: a retrospective cohort study Open
Background Current findings on the necessity of adding exogenous luteinizing hormone (LH) to IVF/ICSI cycles in elderly women(≥ 35 years) with Polycystic ovary syndrome（PCOS）are controversial. This study investigated the clinical efficacy …
View article: The effect of adding exogenous LH to IVF/ICSI cycles on pregnancy outcomes in elderly women with PCOS: a retrospective cohort study
The effect of adding exogenous LH to IVF/ICSI cycles on pregnancy outcomes in elderly women with PCOS: a retrospective cohort study Open
Background Polycystic ovary syndrome (PCOS) patients have more sinus follicular reserve than normal women. However, deteriorating oocyte quality with advancing age is a major problem in PCOS patients undergoing in vitro fertilization (IVF)…