Wen‐Hsing Cheng
YOU?
Author Swipe
View article: Ruminococcus torques Administration Modestly Alleviates Dietary Selenium Deficiency- Induced Glucose Intolerance in Mature Female Mice
Ruminococcus torques Administration Modestly Alleviates Dietary Selenium Deficiency- Induced Glucose Intolerance in Mature Female Mice Open
We previously found that dietary selenium (Se) deficiency and age increase the fecal abundance of Lachnospiraceae in aged telomere-humanized mice in a sexually dimorphic manner. Although Lachnospiraceae are key contributors of short-chain …
View article: Evaluation of different DNA extraction methods for the detection of Clostridium perfringens by loop-mediated isothermal amplification (LAMP) assay
Evaluation of different DNA extraction methods for the detection of Clostridium perfringens by loop-mediated isothermal amplification (LAMP) assay Open
SUMMARY: Clostridium perfringens (C. perfringens) is a gram-positive bacterium that causes necrotic enteritis in poultry, resulting in significant economic losses. The development of a reliable and cost-effective diagnostic assay is crucia…
View article: Using Integrated Bioinformatics Analysis to Identify Saponin Formosanin C as a Ferroptosis Inducer in Colorectal Cancer with p53 and Oncogenic KRAS
Using Integrated Bioinformatics Analysis to Identify Saponin Formosanin C as a Ferroptosis Inducer in Colorectal Cancer with p53 and Oncogenic KRAS Open
Ferroptosis, a form of cell death, is characterized by lipid peroxidation and is dependent on iron and reactive oxygen species (ROS). Here, through bioinformatics analysis, formosanin C was predicted to be a ferroptosis inducer in colorect…
View article: Dietary Selenium Deficiency Accelerates the Onset of Aging‐Related Gut Microbial Changes in Aged Telomere‐Humanized Mice, With <scp><i>Akkermansia muciniphila</i></scp> Being the Most Prominent and Alleviating Selenium Deficiency‐Induced Type 2 Diabetes
Dietary Selenium Deficiency Accelerates the Onset of Aging‐Related Gut Microbial Changes in Aged Telomere‐Humanized Mice, With <span><i>Akkermansia muciniphila</i></span> Being the Most Prominent and Alleviating Selenium Deficiency‐Induced Type 2 Diabetes Open
Previous studies have shown that dietary selenium (Se) deficiency in mice reshapes gut microbiota, exacerbates healthspan deterioration (e.g., type 2 diabetes), and paradoxically activates beneficial longevity pathways. This study demonstr…
View article: Ursodeoxycholic Acid Exhibits Greater Inhibitory Effects on Cancerous HCT116 Colon Cells than on Noncancerous NCM460 Colon Cells
Ursodeoxycholic Acid Exhibits Greater Inhibitory Effects on Cancerous HCT116 Colon Cells than on Noncancerous NCM460 Colon Cells Open
Background/Objectives: Ursodeoxycholic acid (UDCA), a hydrophilic bile acid, exhibits anti-inflammatory effects and attenuates the process of colon carcinogenesis. Certain healthy diets increase colonic UDCA concentrations, but its antican…
View article: Optimization of a loop-mediated isothermal amplification (lamp) assay for the rapid detection of Clostridium perfringens
Optimization of a loop-mediated isothermal amplification (lamp) assay for the rapid detection of Clostridium perfringens Open
Summary: This study developed and optimized a loop-mediated isothermal amplification (LAMP) assay for the rapid, sensitive, and specific detection of Clostridium perfringens (C. perfringens), a key pathogen in necrotic enteritis in poultry…
View article: Editorial
Editorial Open
View article: P13-048-23 Ursodeoxycholic Acid Induces Cell Cycle Arrest and Apoptosis in Cancerous HCT116 Colon Cells but to a Lesser Extent in Noncancerous NCM460 Colon Cells
P13-048-23 Ursodeoxycholic Acid Induces Cell Cycle Arrest and Apoptosis in Cancerous HCT116 Colon Cells but to a Lesser Extent in Noncancerous NCM460 Colon Cells Open
View article: Development and Validation of Nutrition and Food Safety Educational Material for Fish Processors in Nigeria
Development and Validation of Nutrition and Food Safety Educational Material for Fish Processors in Nigeria Open
Introduction: fish can be an affordable and accessible animal-source food in many Low- and Middle-Income Countries (LMIC). Background: Traditional fish processing methods pose a risk of exposing fish to various contaminants that may reduce…
View article: Changes in the Fecal Metabolome Accompany an Increase in Aberrant Crypt Foci in the Colon of C57BL/6 Mice Fed with a High-Fat Diet
Changes in the Fecal Metabolome Accompany an Increase in Aberrant Crypt Foci in the Colon of C57BL/6 Mice Fed with a High-Fat Diet Open
High-fat diet (HFD)-induced obesity is a risk factor for colon cancer. Our previous data show that compared to an AIN-93 diet (AIN), a HFD promotes azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) formation and microbial dysbio…
View article: Selenium status and type 2 diabetes risk
Selenium status and type 2 diabetes risk Open
View article: Food Insecurity and Depression among US Adults: NHANES 2005–2016
Food Insecurity and Depression among US Adults: NHANES 2005–2016 Open
A growing body of evidence suggests that food insecurity is associated with adverse mental health outcomes such as depression and anxiety. In this study, the relationship between food insecurity and depression was examined using data from …
View article: Prevalence, Antimicrobial Resistance, and Molecular Characterization of <i>Campylobacter</i> Isolated from Broilers and Broiler Meat Raised without Antibiotics
Prevalence, Antimicrobial Resistance, and Molecular Characterization of <i>Campylobacter</i> Isolated from Broilers and Broiler Meat Raised without Antibiotics Open
Campylobacter is one of the main bacterial pathogens that cause campylobacteriosis in the United States. Poultry is considered a major reservoir for the transmission of Campylobacter to humans.
View article: Vulnerability of Triple-Negative Breast Cancer to Saponin Formosanin C-Induced Ferroptosis
Vulnerability of Triple-Negative Breast Cancer to Saponin Formosanin C-Induced Ferroptosis Open
Targeting ferritin via autophagy (ferritinophagy) to induce ferroptosis, an iron- and reactive oxygen species (ROS)-dependent cell death, provides novel strategies for cancer therapy. Using a ferroptosis-specific inhibitor and iron chelato…
View article: Deoxycholic Acid Modulates Cell-Junction Gene Expression and Increases Intestinal Barrier Dysfunction
Deoxycholic Acid Modulates Cell-Junction Gene Expression and Increases Intestinal Barrier Dysfunction Open
Diet-related obesity is associated with increased intestinal hyperpermeability. High dietary fat intake causes an increase in colonic bile acids (BAs), particularly deoxycholic acid (DCA). We hypothesize that DCA modulates the gene express…
View article: Identification of Selenoprotein H Isoforms and Impact of Selenoprotein H Overexpression on Protein But Not mRNA Levels of 2 Other Selenoproteins in 293T Cells
Identification of Selenoprotein H Isoforms and Impact of Selenoprotein H Overexpression on Protein But Not mRNA Levels of 2 Other Selenoproteins in 293T Cells Open
View article: Deoxycholic Acid Modulates Cell-Junction Gene Expression and Increases Intestinal Barrier Dysfunction in Caco-2 Cell Monolayers
Deoxycholic Acid Modulates Cell-Junction Gene Expression and Increases Intestinal Barrier Dysfunction in Caco-2 Cell Monolayers Open
View article: Low-Level Tolerance to Fluoroquinolone Antibiotic Ciprofloxacin in QAC-Adapted Subpopulations of Listeria monocytogenes
Low-Level Tolerance to Fluoroquinolone Antibiotic Ciprofloxacin in QAC-Adapted Subpopulations of Listeria monocytogenes Open
There was a development of low-level tolerance to fluoroquinolone antibiotic ciprofloxacin in Listeria monocytogenes after sublethal adaptation to quaternary ammonium compound (QAC). Using eight L. monocytogenes strains, we determined the …
View article: Dietary Selenium Requirement for the Prevention of Glucose Intolerance and Insulin Resistance in Middle-Aged Mice
Dietary Selenium Requirement for the Prevention of Glucose Intolerance and Insulin Resistance in Middle-Aged Mice Open
View article: Superior Inhibitory Efficacy of Butyrate over Propionate and Acetate Against Human Colon Cancer Cell Proliferation via Cell Cycle Arrest and Apoptosis
Superior Inhibitory Efficacy of Butyrate over Propionate and Acetate Against Human Colon Cancer Cell Proliferation via Cell Cycle Arrest and Apoptosis Open
View article: Minimum Dietary Selenium Requirement to Prevent Type 2 Diabetes in Mice
Minimum Dietary Selenium Requirement to Prevent Type 2 Diabetes in Mice Open
View article: Selenoprotein T Promotes Proliferation and G1-to-S Transition in SK-N-SH Cells: Implications in Parkinson's Disease
Selenoprotein T Promotes Proliferation and G1-to-S Transition in SK-N-SH Cells: Implications in Parkinson's Disease Open
View article: Green Tea: An Ancient Antioxidant Drink for Optimal Health?
Green Tea: An Ancient Antioxidant Drink for Optimal Health? Open
View article: Genome Maintenance by Selenoprotein H in the Nucleolus (OR11-03-19)
Genome Maintenance by Selenoprotein H in the Nucleolus (OR11-03-19) Open
OBJECTIVES: Selenoprotein H (SELENOH) was found to localize in the nucleolus and is a member of the thioredoxin-like family of selenoproteins carrying the redox-regulatory CXXU domain. The presence of an AT-hook motif also entitles SELENOH…
View article: Issue Information
Issue Information Open
View article: Selenium Status Influences Selenoprotein H Interactions with Other Selenoproteins in the Response to Oxidative Stress (P24-026-19)
Selenium Status Influences Selenoprotein H Interactions with Other Selenoproteins in the Response to Oxidative Stress (P24-026-19) Open
View article: Advanced Liver Steatosis Accompanies an Increase in the Level of Colonic Pro-inflammatory Bile Acids and Hepatic Inflammation in C57BL/6 Mice Fed a High-fat Diet (P15-027-19)
Advanced Liver Steatosis Accompanies an Increase in the Level of Colonic Pro-inflammatory Bile Acids and Hepatic Inflammation in C57BL/6 Mice Fed a High-fat Diet (P15-027-19) Open
View article: Issue Information
Issue Information Open
View article: Issue Information
Issue Information Open
View article: Issue Information
Issue Information Open