Wenjin Hao
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View article: Self-assembled magnesium peroxide supramolecular hydrogel for oxidants neutralization and chemical burn management
Self-assembled magnesium peroxide supramolecular hydrogel for oxidants neutralization and chemical burn management Open
Supramolecular hydrogels have emerged as a transformative strategy for burn wound management due to their dynamic adaptability and bio-interfacial responses. Herein, a self-assembled magnesium peroxide (MPO) supramolecular hydrogel was eng…
View article: An egg parasitoid assesses host egg quality from afar using oviposition-induced plant volatiles
An egg parasitoid assesses host egg quality from afar using oviposition-induced plant volatiles Open
Parasitoids of herbivores exploit inducible plant volatiles to find plants with potential hosts from a distance, whereas at close range they typically use host-derived cues to pinpoint and identify suitable hosts. Here, we show, however, t…
View article: Molecular and cellular basis of life cycle transition provides new insights into ecological adaptation in jellyfish
Molecular and cellular basis of life cycle transition provides new insights into ecological adaptation in jellyfish Open
Jellyfish are renowned for their complex life cycles and important ecological and evolutionary position. The unique transition from the sessile polyp to motile medusa stages is a key process determining a switch in jellyfish behaviour and …
View article: Marine Bacterial Communities in the Xisha Islands, South China Sea
Marine Bacterial Communities in the Xisha Islands, South China Sea Open
Oligotrophic marine environments are ecological funnels in marine ecosystems and are essential for maintaining the health and balance of the entire marine ecosystem. Bacterial communities are one of the most important biological population…
View article: Luteolin induces apoptosis by impairing mitochondrial function and targeting the intrinsic apoptosis pathway in gastric cancer cells
Luteolin induces apoptosis by impairing mitochondrial function and targeting the intrinsic apoptosis pathway in gastric cancer cells Open
Gastric cancer is one of the most lethal cancers worldwide. Research has focused on exploring natural medicines to improve the systematic chemotherapy for gastric cancer. Luteolin, a natural flavonoid, possesses anticancer activities. Neve…
View article: Single-cell transcriptomic analyses reveal the cellular and genetic basis of aquatic locomotion in scyphozoan jellyfish
Single-cell transcriptomic analyses reveal the cellular and genetic basis of aquatic locomotion in scyphozoan jellyfish Open
The authors have withdrawn their manuscript because the authors need to re-organize the data and writing. More experimental evidence from whole-mount ISH assay and RNAi assays will be added to support the viewpoints. Therefore, the authors…
View article: Composition and Potential Functions of Bacterial Communities Associated With Aurelia Polyps
Composition and Potential Functions of Bacterial Communities Associated With Aurelia Polyps Open
Jellyfish and their associated microbes form an ecological unit called the holobiont. Changes in the composition of dominant microbial assemblages may influence the environmental resilience and function of the holobionts. Differentiating t…
View article: Luteolin potentiates low‑dose oxaliplatin‑induced inhibitory effects on cell proliferation in gastric cancer by inducing G2/M cell cycle arrest and apoptosis
Luteolin potentiates low‑dose oxaliplatin‑induced inhibitory effects on cell proliferation in gastric cancer by inducing G2/M cell cycle arrest and apoptosis Open
Although the reduction of oxaliplatin doses may alleviate deleterious side effects of gastrointestinal and gynecological cancer treatment, it also limits the anticancer therapeutic effects. As a high-efficient and low-priced herbal medicin…
View article: Bacterial Communities Associated With Four Blooming Scyphozoan Jellyfish: Potential Species-Specific Consequences for Marine Organisms and Humans Health
Bacterial Communities Associated With Four Blooming Scyphozoan Jellyfish: Potential Species-Specific Consequences for Marine Organisms and Humans Health Open
Cnidarians have large surface areas available for colonization by microbial organisms, which serve a multitude of functions in the environment. However, relatively few studies have been conducted on scyphozoan-associated microbial communit…
View article: Biomass Cellulose Nanoparticles Display Considerable Neurotoxicity in Zebrafish
Biomass Cellulose Nanoparticles Display Considerable Neurotoxicity in Zebrafish Open
BackgroundThe widespread use of nanomaterials poses a great threat to human living environments. Among them, biomass cellulose nanoparticle (CN) is one of the widely used nanomaterials. To date, the toxicity of CNs during embryonic develop…
View article: Expression analysis of Rab11 during zebrafish embryonic development
Expression analysis of Rab11 during zebrafish embryonic development Open
Background: Rab proteins are GTPases responsible for intracellular vesicular trafficking regulation. Rab11 proteins, members of the Rab GTPase family, are known to regulate vesicular recycling during embryonic development. In zebrafish, th…
View article: Expression analysis of Rab11 during zebrafish embryonic development
Expression analysis of Rab11 during zebrafish embryonic development Open
Background: Rab proteins are GTPases responsible for intracellular vesicular trafficking regulation. Rab11 proteins, members of the Rab GTPase family, are known to regulate vesicular recycling during embryonic development. In zebrafish, th…
View article: Bufotalin induces cell cycle arrest and cell apoptosis in human malignant melanoma A375 cells
Bufotalin induces cell cycle arrest and cell apoptosis in human malignant melanoma A375 cells Open
Venenum bufonis has been used as an antitumor drug in China for many years. Bufotalin, as an active component of Venenum bufonis, has been proven to exhibit antitumor effects in cancer types. In the present study, the effect of bufotalin o…
View article: Isoliquiritigenin Induces Mitochondrial Dysfunction and Apoptosis by Inhibiting mitoNEET in a Reactive Oxygen Species-Dependent Manner in A375 Human Melanoma Cells
Isoliquiritigenin Induces Mitochondrial Dysfunction and Apoptosis by Inhibiting mitoNEET in a Reactive Oxygen Species-Dependent Manner in A375 Human Melanoma Cells Open
The mitochondrial protein mitoNEET is a type of iron-sulfur protein localized to the outer membrane of mitochondria and is involved in a variety of human pathologies including cystic fibrosis, diabetes, muscle atrophy, and neurodegeneratio…
View article: Licochalcone�D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells
Licochalcone�D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells Open
The aim of the present study was to determine the effects of Licochalcone D (LD) on the apoptosis and migration and invasion in human melanoma A375 cells. Cell proliferation was determined by sulforhodamine B assay. Apoptosis was assessed …
View article: Eriodictyol Attenuates Myocardial Ischemia-Reperfusion Injury through the Activation of JAK2
Eriodictyol Attenuates Myocardial Ischemia-Reperfusion Injury through the Activation of JAK2 Open
Myocardial ischemia-reperfusion (I/R) injury remains the leading risk factor of disability and mortality worldwide. In this study, the myocardial protective effect of eriodictyol (EDT) and the underlying mechanism in an ex vivo model of gl…
View article: Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2-p38-JNK-dependent pathway
Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2-p38-JNK-dependent pathway Open
Icariin (ICA) is a major component isolated from Epimedium brevicornum. Emerging evidence shows that ICA can inhibit tumor cell proliferation, invasion and migration. However, the anti-cancer effect of ICA on B16 cells has not been fully i…
View article: Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma
Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma Open
The cardiac ischemia-reperfusion (I/R) injury greatly influences the therapeutic effect and remains an urgent challenge in clinical therapy. Polypharmacology opens a new therapeutic opportunity to design drugs with a specific target for im…
View article: Kaempferide Protects against Myocardial Ischemia/Reperfusion Injury through Activation of the PI3K/Akt/GSK-3<i>β</i> Pathway
Kaempferide Protects against Myocardial Ischemia/Reperfusion Injury through Activation of the PI3K/Akt/GSK-3<i>β</i> Pathway Open
The aim of this study is to investigate both the efficacy and mechanism of action of kaempferide (Kae) as a therapy for the treatment of cardiovascular disease. A rat model of myocardial ischemia/reperfusion (I/R) injury was established by…
View article: Alternol inhibits the proliferation and induces the differentiation of the mouse melanoma B16F0 cell line
Alternol inhibits the proliferation and induces the differentiation of the mouse melanoma B16F0 cell line Open
High malignant potential and low susceptibility to treatment are characteristics of malignant melanoma. Alternol, a novel compound purified from microbial fermentation products obtained from the bark of the yew tree, exhibits a variety of …