Wenjing Ji
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View article: Allergy-unrelated eosinophil activation in the peripheral blood of children with neurodevelopmental disorders
Allergy-unrelated eosinophil activation in the peripheral blood of children with neurodevelopmental disorders Open
Background Neurodevelopmental disorders (NDDs) are increasingly associated with immune dysregulation, but eosinophil activation independent of allergic diseases remains unexplored in this population. Methods Peripheral-blood eosinophil cat…
View article: Economic evaluation of prenatal GBS immunization in China: A modeling analysis
Economic evaluation of prenatal GBS immunization in China: A modeling analysis Open
Invasive Group B Streptococcus (GBS) infection is a fatal disease that causes a significant disease burden in young infants worldwide. GBS vaccines being developed are a potential means of preventing GBS; however, their cost-effecti…
View article: Social determinants of health and progression to cardio–renal–metabolic multimorbidity and mortality in people with prediabetes: A prospective cohort study
Social determinants of health and progression to cardio–renal–metabolic multimorbidity and mortality in people with prediabetes: A prospective cohort study Open
Aims Social determinants of health (SDHs) have been increasingly recognised as upstream drivers of preventable health disparities. However, it is unclear what the role of SDHs is in the whole progression of prediabetes. We aimed to delinea…
View article: Determining the impact of the COVID-19 pandemic on the consumption of antibiotics in Shaanxi province, China: an interrupted time-series analysis
Determining the impact of the COVID-19 pandemic on the consumption of antibiotics in Shaanxi province, China: an interrupted time-series analysis Open
Background The COVID-19 pandemic, as well as associated prevention and control measures, have impacted the entire healthcare system, including the use patterns of medicine. However, the impact of COVID-19 on the use of antibiotics has not …
View article: WITHDRAWN: Allergy-unrelated eosinophil activation in the peripheral blood of children with neurodevelopmental disorders
WITHDRAWN: Allergy-unrelated eosinophil activation in the peripheral blood of children with neurodevelopmental disorders Open
View article: Insights into Application Research of the Density Functional Theory in Iron Sulfur Compounds: A Bibliometric Mapping Analysis
Insights into Application Research of the Density Functional Theory in Iron Sulfur Compounds: A Bibliometric Mapping Analysis Open
To more accurately grasp the current status and trends in the density functional theory (DFT) study of iron sulfur compounds, this paper presents a bibliometric analysis of 821 documents from 2000 to 2023. The literature source is the Web …
View article: Primary Healthcare Physicians’ Insufficient Knowledge Is Associated with Antibiotic Overprescribing for Acute Upper Respiratory Tract Infections in China: A Cross-Sectional Study
Primary Healthcare Physicians’ Insufficient Knowledge Is Associated with Antibiotic Overprescribing for Acute Upper Respiratory Tract Infections in China: A Cross-Sectional Study Open
Objectives: Overuse of antibiotics in healthcare remains prevalent and requires urgent attention in China, particularly in primary healthcare (PHC) facilities. This study aimed to describe the patterns of antibiotic prescriptions for acute…
View article: Automated classification of group B Streptococcus into different clonal complexes using MALDI-TOF mass spectrometry
Automated classification of group B Streptococcus into different clonal complexes using MALDI-TOF mass spectrometry Open
Objectives To evaluate the performance of Matrix-Assisted Laser Desorption/Ionization Time-of Flight Mass Spectra (MALDI-TOF MS) for automated classification of GBS (Group B Streptococcus ) into five major CCs (clonal complexes) during rou…
View article: Dispensing of antibiotics for tuberculosis patients using standardized patient approach at community pharmacies: results from a cross-sectional study in Pakistan
Dispensing of antibiotics for tuberculosis patients using standardized patient approach at community pharmacies: results from a cross-sectional study in Pakistan Open
Background Pakistan is among top countries for antibiotic consumption around the globe and patients often receive antibiotics directly from community pharmacies. Thus, our aim was to assess the drug dispensing practices of pharmacies for p…
View article: Preferences of pregnant women toward a future maternal Group B Streptococcus vaccine in China: A cross-sectional survey with a discrete choice experiment
Preferences of pregnant women toward a future maternal Group B Streptococcus vaccine in China: A cross-sectional survey with a discrete choice experiment Open
Group B streptococcus (GBS) is a major cause of neonatal death worldwide. A GBS vaccine for pregnant women is under development and is expected to be available in the near future. The perceptions and preferences of pregnant women in China …
View article: Insights into the Application of Machine Learning in Industrial Risk Assessment: A Bibliometric Mapping Analysis
Insights into the Application of Machine Learning in Industrial Risk Assessment: A Bibliometric Mapping Analysis Open
Risk assessment is of great significance in industrial production and sustainable development. Great potential is attributed to machine learning in industrial risk assessment as a promising technology in the fields of computer science and …
View article: Molecular characteristics and antibiotic resistance mechanisms of clindamycin-resistant Streptococcus agalactiae isolates in China
Molecular characteristics and antibiotic resistance mechanisms of clindamycin-resistant Streptococcus agalactiae isolates in China Open
Streptococcus agalactiae (Group B Streptococcus , GBS) is a major cause of neonatal infections with high morbidity and mortality, and clindamycin is the main antibiotic used to treat GBS infections in patients allergic to penicillin. We ai…
View article: Serotype Distribution, Virulence Determinants and Antimicrobial Susceptibility of Streptococcus agalactiae Isolated from Young Infants
Serotype Distribution, Virulence Determinants and Antimicrobial Susceptibility of Streptococcus agalactiae Isolated from Young Infants Open
Background: Streptococcus agalactiae (Group B Streptococcus, GBS) is the most common cause of serious infections in the first 3 months of life worldwide. The pathogenicity of GBS is closely related to serotypes, surface proteins and virule…
View article: Current situation and future development of the biopharmaceutical industry in China: A mixed-method study
Current situation and future development of the biopharmaceutical industry in China: A mixed-method study Open
Introduction: The biomedical industry has grown significantly both globally and in China; however, there are still challenges. This study aimed at evaluating the biopharmaceutical sector of China, in terms of ability to innovate, current s…
View article: Ultra-Short-Course Antibiotics for Suspected Pneumonia With Preserved Oxygenation
Ultra-Short-Course Antibiotics for Suspected Pneumonia With Preserved Oxygenation Open
Background Suspected pneumonia is the most common indication for antibiotics in hospitalized patients but is frequently overdiagnosed. We explored whether normal oxygenation could be used as an indicator to support early discontinuation of…
View article: Knowledge on Multi-Drug Resistant Pathogens, Antibiotic Use and Self-Reported Adherence to Antibiotic Intake: A Population-Based Cross Sectional Survey From Pakistan
Knowledge on Multi-Drug Resistant Pathogens, Antibiotic Use and Self-Reported Adherence to Antibiotic Intake: A Population-Based Cross Sectional Survey From Pakistan Open
Objective: Surveying public awareness of antibiotic use and antibiotics can identify factors relevant to the design of effective educational campaigns. The aim of this study was to evaluate the knowledge, attitudes, and practices related t…
View article: Investigating intention to receive the COVID-19 vaccine and willingness to pay among the general public in Pakistan
Investigating intention to receive the COVID-19 vaccine and willingness to pay among the general public in Pakistan Open
The Study of Evaluation of Drug Use by Using WHO’S Prescribing, Patient Care and Health Facility Indicators in Selected Health Facilities in Province Punjab, PakistanMuhammad Saeed Akram, Awais Qamar, Usman javid, Abdul Rehman, Farah Bano …
View article: Natural Compound Shikonin Is a Novel PAK1 Inhibitor and Enhances Efficacy of Chemotherapy against Pancreatic Cancer Cells
Natural Compound Shikonin Is a Novel PAK1 Inhibitor and Enhances Efficacy of Chemotherapy against Pancreatic Cancer Cells Open
Shikonin is the main component of root extracts from the Chinese herbal medicine Lithospermum erythrorhizon, which is commonly used for the treatment of various diseases including cancer. Previous research showed that shikonin suppressed p…
View article: Access to Insulin Products in Pakistan: A National Scale Cross-Sectional Survey on Prices, Availability, and Affordability
Access to Insulin Products in Pakistan: A National Scale Cross-Sectional Survey on Prices, Availability, and Affordability Open
Background: Diabetes is among the top ten most prevalent diseases in Pakistan, and the availability of medicines to treat the disease is vital for a great percentage of the country’s population. Insulin was discovered a century ago; howeve…
View article: Analysis of the efficacy and safety of paclitaxel (albumin-bound) combined with S-1 and oxaliplatin combined with S-1 in the first-line treatment of advanced gastric cancer: a cohort study
Analysis of the efficacy and safety of paclitaxel (albumin-bound) combined with S-1 and oxaliplatin combined with S-1 in the first-line treatment of advanced gastric cancer: a cohort study Open
Both regimens can be applied to advanced gastric cancer patients. Albumin-bound paclitaxel showed a higher ORR and could effectively prolong PFS.
View article: The Impact of a National Stewardship Policy on the Usage Patterns of Key Monitoring Drugs in a Tertiary Teaching Hospital: An Interrupted Time Series Analysis
The Impact of a National Stewardship Policy on the Usage Patterns of Key Monitoring Drugs in a Tertiary Teaching Hospital: An Interrupted Time Series Analysis Open
Background: The management of Key Monitoring Drugs has become one of important aspects to control the growth of pharmaceutical expenditures in China. The first batch of the China National Key Monitoring Drugs (NKMDs) policy was released in…
View article: Impact of the Expert Consensus on Carbapenem Consumption Trends and Patterns in Public Healthcare Institutes: An Interrupted Time Series Analysis, 2017–2020
Impact of the Expert Consensus on Carbapenem Consumption Trends and Patterns in Public Healthcare Institutes: An Interrupted Time Series Analysis, 2017–2020 Open
Background: Carbapenems are considered the last line of defence against bacterial infections, but their high consumption and the resulting antibacterial resistance are an increasing global concern. In this context, the Chinese health autho…
View article: Improved efficacy and safety of low-dose oxaliplatin/pegylated liposomal doxorubicin/S-1 regimen in advanced gastric cancer: a cohort study
Improved efficacy and safety of low-dose oxaliplatin/pegylated liposomal doxorubicin/S-1 regimen in advanced gastric cancer: a cohort study Open
Low-dose oxaliplatin combined with S-1 and pegylated liposomal doxorubicin (PLD) regimen improved OS and PFS, while exhibiting better toxicity profile as compared with standard SOX regimen for AGC.
View article: Antimicrobial Stewardship Programs in Northwest China: A Cross-Sectional Survey of Perceptions, Involvement, and Perceived Barriers Among Hospital Pharmacists
Antimicrobial Stewardship Programs in Northwest China: A Cross-Sectional Survey of Perceptions, Involvement, and Perceived Barriers Among Hospital Pharmacists Open
Background: Antimicrobial stewardship (AMS) is a key prevention strategy in addressing the global concern of increasing antimicrobial resistance (AMR). Pharmacists are one of the integral members of AMS hospital teams around the world. Tow…
View article: Rapid Classification of Multilocus Sequence Subtype for Group B Streptococcus Based on MALDI-TOF Mass Spectrometry and Statistical Models
Rapid Classification of Multilocus Sequence Subtype for Group B Streptococcus Based on MALDI-TOF Mass Spectrometry and Statistical Models Open
Group B Streptococcus (GBS) is an important etiological agent of maternal and neonatal infections as well as postpartum women and individuals with impaired immunity. We developed and evaluated a rapid classification method for sequence typ…
View article: Impact of video-led educational intervention on the uptake of influenza vaccine among adults aged 60 years and above in China: a study protocol for a randomized controlled trial
Impact of video-led educational intervention on the uptake of influenza vaccine among adults aged 60 years and above in China: a study protocol for a randomized controlled trial Open
Background Influenza is a global health threat to older adults, and the influenza vaccine is the most effective approach to prevent influenza infection. However, influenza vaccination coverage among Chinese older adults is far less than in…
View article: Access to Essential Cardiovascular Medicines in Pakistan: A National Survey on the Availability, Price, and Affordability, Using WHO/HAI Methodology
Access to Essential Cardiovascular Medicines in Pakistan: A National Survey on the Availability, Price, and Affordability, Using WHO/HAI Methodology Open
Objective: This national survey was aimed at measuring the access to cardiovascular disease (CVD) medicines in terms of their availability, price, and affordability in Pakistan. This was done by using the standard WHO/Health Action Interna…
View article: Predominance of III/ST19 and Ib/ST10 Lineages With High Multidrug Resistance in Fluoroquinolone-Resistant Group B Streptococci Isolates in Which a New Integrative and Conjugative Element Was Identified
Predominance of III/ST19 and Ib/ST10 Lineages With High Multidrug Resistance in Fluoroquinolone-Resistant Group B Streptococci Isolates in Which a New Integrative and Conjugative Element Was Identified Open
Fluoroquinolone (FQ)-resistant Group B Streptococcus (GBS) has been reported with considerable cross-resistance, worsening the crisis of multidrug-resistant (MDR) GBS in clinical settings. However, national epidemiological data on FQ-resis…
View article: Trends in Consumption of Quinolones in Chinese Healthcare Institutions: Results of National Procurement Data Analysis (2015–2018)
Trends in Consumption of Quinolones in Chinese Healthcare Institutions: Results of National Procurement Data Analysis (2015–2018) Open
Background There is widespread use of quinolones to treat various infectious diseases due to their broad-spectrum nature and optimal pharmacokinetic characteristics. Nevertheless, the risk of bacterial resistance has also amplified as a co…
View article: Antibiotics (Macrolides and Lincosamides) Consumption Trends and Patterns in China’s Healthcare Institutes. Based on a 3 Year Procurement Records, 2015–2017
Antibiotics (Macrolides and Lincosamides) Consumption Trends and Patterns in China’s Healthcare Institutes. Based on a 3 Year Procurement Records, 2015–2017 Open
In this study, we investigated the trends and patterns of antibiotic consumption (macrolides and lincosamides) in China’s healthcare institutions from 2015 to 2017. The China Drug Supply Information Platform (CDSIP) was officially launched…