Wenjuan Yan
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View article: Factors influencing stigma in Chinese postoperative breast cancer patients: a systematic review and meta-analysis
Factors influencing stigma in Chinese postoperative breast cancer patients: a systematic review and meta-analysis Open
Objective To systematically evaluate stigma levels and its influencing factors among Chinese postoperative breast cancer patients, providing evidence for culturally adapted interventions. Methods Chinese and English databases, such as Chin…
View article: Comparable immune escape capacity between KP.2 and other SARS-CoV-2 variants in the central Chinese population after the first COVID-19 booster
Comparable immune escape capacity between KP.2 and other SARS-CoV-2 variants in the central Chinese population after the first COVID-19 booster Open
The neutralisation ability of homologous and heterologous booster vaccinations against the KP.2 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. Therefore, we aimed to evaluate the neutralisation of the O…
View article: Biomimetic Microstructured Scaffold with Release of Re‐Modified Teriparatide for Osteoporotic Tendon‐to‐Bone Regeneration via Balancing Bone Homeostasis
Biomimetic Microstructured Scaffold with Release of Re‐Modified Teriparatide for Osteoporotic Tendon‐to‐Bone Regeneration via Balancing Bone Homeostasis Open
Osteoporotic tendon‐to‐bone interface healing is challenging, with a high surgical repair failure rate of up to 68%. Conventional tissue engineering approaches have primarily focused on promoting interface healing by stimulating regenerati…
View article: Nanotherapies Based on ROS Regulation in Oral Diseases
Nanotherapies Based on ROS Regulation in Oral Diseases Open
Oral diseases rank among the most prevalent clinical conditions globally, typically involving detrimental factors such as infection, inflammation, and injury in their occurrence, development, and outcomes. The concentration of reactive oxy…
View article: Comparable Immune Escape Capacity Between KP.2 and Other SARS-CoV-2 Variants in the Central Chinese Population After the First COVID-19 Booster
Comparable Immune Escape Capacity Between KP.2 and Other SARS-CoV-2 Variants in the Central Chinese Population After the First COVID-19 Booster Open
The neutralisation ability of homologous and heterologous booster vaccinations against the KP.2 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. We evaluated Omicron variants (XBB.1, JN.1, and KP.2) neutr…
View article: Chinese dentists’ restorative preferences and choices for endodontically treated teeth: a representative survey
Chinese dentists’ restorative preferences and choices for endodontically treated teeth: a representative survey Open
Background The optimal restoration protocol for endodontically treated teeth (ETT) remains a subject of debate. This survey aims to assess the current level of awareness, knowledge, and prevailing opinions among dental practitioners in Chi…
View article: The Mechanisms and Application Value of Postbiotics in Caries Prevention and Management.
The Mechanisms and Application Value of Postbiotics in Caries Prevention and Management. Open
Dental caries, one of the most prevalent diseases globally, affects individuals throughout their lifetimes. Recently, researchers have increasingly focused on postbiotics for caries prevention. Postbiotics, comprising inanimate microorgani…
View article: Optimizing restorative procedure and material selection for pulpotomized primary molars: Mechanical characterization by 3D finite element analysis
Optimizing restorative procedure and material selection for pulpotomized primary molars: Mechanical characterization by 3D finite element analysis Open
View article: Injective Hydrogel Encapsulated with Liposomal MY-1 Promotes the Skin Wound Closure and Enhanced Tensile Strength by Accelerating Fibroblast Migration Via the PI3K/AKT-Rac1 Signaling Pathway
Injective Hydrogel Encapsulated with Liposomal MY-1 Promotes the Skin Wound Closure and Enhanced Tensile Strength by Accelerating Fibroblast Migration Via the PI3K/AKT-Rac1 Signaling Pathway Open
View article: Restorative preferences and choices for endodontically treated teeth: a representative survey in China
Restorative preferences and choices for endodontically treated teeth: a representative survey in China Open
Background The optimal protocol for restoring endodontically treated teeth (ETT) remains unclear due to various considerations such as coronal restoration type, and the amount of remaining coronal structure. This study aims to compare Chin…
View article: Correction: Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activation
Correction: Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activation Open
View article: Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activation
Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activation Open
Background Re-epithelialization is important in the process of wound healing. Various methods have been identified to expedite the process, but their clinical application remains limited. While parathyroid hormone (PTH) has shown promising…
View article: MY‐1‐Loaded Nano‐Hydroxyapatite Accelerated Bone Regeneration by Increasing Type III Collagen Deposition in Early‐Stage ECM via a Hsp47‐Dependent Mechanism (Adv. Healthcare Mater. 20/2023)
MY‐1‐Loaded Nano‐Hydroxyapatite Accelerated Bone Regeneration by Increasing Type III Collagen Deposition in Early‐Stage ECM via a Hsp47‐Dependent Mechanism (Adv. Healthcare Mater. 20/2023) Open
Osteogenesis In article 2300332 by Shao Longquan, Yang Dehong, Yan Wenjuan and co-workers, the peptide MY-1-loaded nHA can extend the MY-1 releasing period in a local bone defect. Then, MY-1 is endocytosed by parathyroid hormone 1 receptor…
View article: Impaired angiogenesis in ageing: the central role of the extracellular matrix
Impaired angiogenesis in ageing: the central role of the extracellular matrix Open
View article: Effect of virtual cement space and restorative materials on the adaptation of CAD-CAM endocrowns
Effect of virtual cement space and restorative materials on the adaptation of CAD-CAM endocrowns Open
View article: Effects of N-cadherin silencing on the proliferation and migration of human dental pulp stem cells
Effects of N-cadherin silencing on the proliferation and migration of human dental pulp stem cells Open
Objective To investigate the effects of N-cadherin silencing on the proliferation and migration of human dental pulp stem cells (DPSCs) and to provide experimental evidence for DPSCs-based dental pulp regeneration. Methods DPSCs were trans…
View article: Anti-Inflammatory and Mineralization Effects of an ASP/PLGA-ASP/ACP/PLLA-PLGA Composite Membrane as a Dental Pulp Capping Agent
Anti-Inflammatory and Mineralization Effects of an ASP/PLGA-ASP/ACP/PLLA-PLGA Composite Membrane as a Dental Pulp Capping Agent Open
Dental pulp is essential for the development and long-term preservation of teeth. Dental trauma and caries often lead to pulp inflammation. Vital pulp therapy using dental pulp-capping materials is an approach to preserving the vitality of…
View article: MiR-4268 suppresses gastric cancer genesis through inhibiting keratin 80
MiR-4268 suppresses gastric cancer genesis through inhibiting keratin 80 Open
Gastric cancer (GC) affects a large proportion of cancer patients worldwide, and the prediction of potential biomarkers can greatly improve its diagnosis and treatment. Here, miR-4268 and keratin 80 (KRT80) expression in GC tissues and cel…
View article: Retraction Note: Comparison of indirect pulp treatment and iRoot BP Plus pulpotomy in primary teeth with extremely deep caries: a prospective randomized trial
Retraction Note: Comparison of indirect pulp treatment and iRoot BP Plus pulpotomy in primary teeth with extremely deep caries: a prospective randomized trial Open
View article: Influence of margin design and restorative material on the stress distribution of endocrowns: a 3D finite element analysis
Influence of margin design and restorative material on the stress distribution of endocrowns: a 3D finite element analysis Open
Background This study aimed to evaluate the stress distributions in endocrown restorations as applied to endodontically treated teeth (ETT), according to the factors of “margin design” (four levels) and “restorative material” (six levels).…
View article: The Clinical Aspects and Prognostic Factors Concerning Survival in Patients With Recurrent Cervical Cancer After Radical Hysterectomy and Adjuvant Chemoradiotherapy
The Clinical Aspects and Prognostic Factors Concerning Survival in Patients With Recurrent Cervical Cancer After Radical Hysterectomy and Adjuvant Chemoradiotherapy Open
Purpose To investigate the recurrence patterns and prognostic factors of patients with recurrent cervical cancer after radical hysterectomy with node dissection (RHND) followed by adjuvant radiotherapy (RT)/concurrent chemoradiotherapy (CC…
View article: Influence of restorative material and cement on the stress distribution of endocrowns: 3D finite element analysis
Influence of restorative material and cement on the stress distribution of endocrowns: 3D finite element analysis Open
Purpose This study aimed to evaluate the influence of different types of restorative materials and resin cements on the stress distribution in the regions of the restoration, cement layer and dental remnant in endodontically treated poster…
View article: Effect of Heat Softening versus Ultrasonic Removal of Root-End Gutta-Percha on the Quality of Root-End Preparation for Endodontic Microsurgery
Effect of Heat Softening versus Ultrasonic Removal of Root-End Gutta-Percha on the Quality of Root-End Preparation for Endodontic Microsurgery Open
This study is aimed at comparing the efficacy of heat softening and ultrasonic removal of root-end gutta-percha during retrograde preparation for root apical microsurgery. Recently extracted single-rooted premolars ( n = 40 ) were prepar…
View article: Case Report: A Novel COL1A1 Missense Mutation Associated With Dentineogenesis Imperfecta Type I
Case Report: A Novel COL1A1 Missense Mutation Associated With Dentineogenesis Imperfecta Type I Open
Background: Osteogenesis imperfecta (OI) is a clinical and genetic disorder that results in bone fragility, blue sclerae and dentineogenesis imperfecta (DGI), which is mainly caused by a mutation in the COL1A1 or COL1A2 genes, which encode…
View article: Clinical Aspects and Prognostic Factors for Survival in Patients with Recurrent Cervical Cancer after Radical Hysterectomy and Adjuvant Radiochemotherapy
Clinical Aspects and Prognostic Factors for Survival in Patients with Recurrent Cervical Cancer after Radical Hysterectomy and Adjuvant Radiochemotherapy Open
Purpose To investigate the recurrence patterns and prognostic factors of patients with recurrent cervical cancer after radical hysterectomy with node dissection (RHND) followed by adjuvant radiotherapy (RT)/concurrent radiochemotherapy (CC…
View article: Whole Exome Sequencing Identifies a Novel COL1A1 Missense Mutation Causing Dentinogenesis Imperfecta Type I Without Skeletal Abnormalities
Whole Exome Sequencing Identifies a Novel COL1A1 Missense Mutation Causing Dentinogenesis Imperfecta Type I Without Skeletal Abnormalities Open
Background： Osteogenesis imperfecta (OI) is a genetic disorder characterized by bone fragility, blue sclerae and dentinogenesis imperfecta (DGI), which are mainly caused by a mutation of the COL1A1 or COL1A2 genes that encode type I procol…
View article: N-Cadherin Regulates the Odontogenic Differentiation of Dental Pulp Stem Cells via β-Catenin Activity
N-Cadherin Regulates the Odontogenic Differentiation of Dental Pulp Stem Cells via β-Catenin Activity Open
Dental pulp stem cell (DPSC) transplantation has shown new prospects in dental pulp regeneration, and is of great significance in the treatment of pulpitis and pulp necrosis. The fate and regenerative potential of stem cells are dependent,…
View article: [Clinical performance of rensin-bonded composite strip crowns in primary incisors].
[Clinical performance of rensin-bonded composite strip crowns in primary incisors]. Open
Strip crowns performed well for restoring primary incisors with large or multisurface caries for periods of over 18 months. The strip crowns can be a durable and aesthetic restoration for vital carious primary incisors with adequate tooth …
View article: Clinical efficacy of ceramic versus resin-based composite endocrowns in Chinese adults: study protocol for a randomized controlled trial
Clinical efficacy of ceramic versus resin-based composite endocrowns in Chinese adults: study protocol for a randomized controlled trial Open
View article: hPTH(3-34)(29-34) selectively activated PKC and mimicked osteoanabolic effects of hPTH(1-34)
hPTH(3-34)(29-34) selectively activated PKC and mimicked osteoanabolic effects of hPTH(1-34) Open
Teriparatide (hPTH(1-34)) exhibits both osteoanabolic and osteocatabolic effects. We generated a novel PTH analog by duplicating the PTH(29-34) domain to hPTH(3-34) (named MY-1), which was identified to activate PKC but not PLC and cAMP/PK…