Wei Hong
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View article: Non-antibiotic nanoplatform based CuS/AuNCs@Lip NPs for inhibition pneumonia caused by MRSA and its mechanism exploration
Non-antibiotic nanoplatform based CuS/AuNCs@Lip NPs for inhibition pneumonia caused by MRSA and its mechanism exploration Open
View article: Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot
Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot Open
Tumor immunotherapy has garnered significant attention, however, several notable challenges remain to be addressed, including: 1) enhancing active targeting, 2) effectively shielding immune checkpoints, and 3) inducing the transformation o…
View article: Feasibility, efficacy, and safety of ventral caudal artery access for transarterial chemoembolization in a rat hepatocellular carcinoma model
Feasibility, efficacy, and safety of ventral caudal artery access for transarterial chemoembolization in a rat hepatocellular carcinoma model Open
VCA access is feasible, effective, safe for TACE in rat HCC model.
View article: University-industry linkages in a changing policy environment: Regional knowledge flows in China.
University-industry linkages in a changing policy environment: Regional knowledge flows in China. Open
University-industry linkages in a changing policy environment: Regional knowledge flows in China.
View article: H2 Production from Pyrolysis-Steam Reforming of Municipal Solid Waste and Biomass: A Comparative Study When Using the Self-Derived Char-Based Catalysts
H2 Production from Pyrolysis-Steam Reforming of Municipal Solid Waste and Biomass: A Comparative Study When Using the Self-Derived Char-Based Catalysts Open
This study employed a two-stage fixed-bed pyrolysis-reforming reactor to investigate H2 production behaviors from municipal solid waste (MSW) and biomass with their self-derived catalysts under different operating parameters. The self-deri…
View article: pH/Hyal-responsive vancomycin-loaded chitooligosaccharide nanoparticles for intracellular MRSA infection treatment
pH/Hyal-responsive vancomycin-loaded chitooligosaccharide nanoparticles for intracellular MRSA infection treatment Open
View article: A randomized controlled trial to compare the effect of oxycodone and sufentanil on postoperative analgesia and immune function for laparoscopic resection of colorectal cancer
A randomized controlled trial to compare the effect of oxycodone and sufentanil on postoperative analgesia and immune function for laparoscopic resection of colorectal cancer Open
View article: The amplitude of low frequency fluctuation and spontaneous brain activity alterations in age-related macular degeneration
The amplitude of low frequency fluctuation and spontaneous brain activity alterations in age-related macular degeneration Open
Background Wet age-related macular degeneration (wAMD) is a vision-threatening eye disease worldwide. The amplitude of low-frequency fluctuation (ALFF) method was used to observe changes in spontaneous brain activity, which may help to inv…
View article: The salt crystal structure of etoricoxib hydrochloride, C<sub>18</sub>H<sub>16</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>2</sub>S
The salt crystal structure of etoricoxib hydrochloride, C<sub>18</sub>H<sub>16</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>2</sub>S Open
C 18 H 16 Cl 2 N 2 O 2 S, monoclinic, P 2 1 / c (no. 14), a = 10.915(2) Å, b = 11.801(2) Å, c = 14.059(3) Å, β = 90.10(3)°, V = 1810.9(6) Å 3 , Z = 4, R gt ( F ) = 0.0585, wR ref ( F 2 ) = 0.1532, T = 293(2) K.
View article: A randomized controlled trail to compare the effect of oxycodone and sufentanil on postoperative analgesia and immune function for laparoscopic resection of colorectal cancer
A randomized controlled trail to compare the effect of oxycodone and sufentanil on postoperative analgesia and immune function for laparoscopic resection of colorectal cancer Open
Background The purpose of this study is to evaluate the effect of oxycodone and sufentanil on postoperative analgesia and immune function in patients with laparoscopic resection of colorectal cancer (CRC), as well as the serum level of inf…
View article: Amphiphilic Janus Nanoparticles for Effective Treatment of Bacterial Pneumonia by Attenuating Inflammation and Targeted Bactericidal Capability
Amphiphilic Janus Nanoparticles for Effective Treatment of Bacterial Pneumonia by Attenuating Inflammation and Targeted Bactericidal Capability Open
In conclusion, our investigation introduced a promising approach to the treatment of pneumonia associated with PAO1.
View article: The dorsomedial prefrontal cortex promotes self-control by inhibiting the egocentric perspective
The dorsomedial prefrontal cortex promotes self-control by inhibiting the egocentric perspective Open
The dorsomedial prefrontal cortex (dmPFC) plays a crucial role in social cognitive functions, including perspective-taking. Although perspective-taking has been linked to self-control, the mechanism by which the dmPFC might facilitate self…
View article: The interaction of oxytocin and nicotine addiction on psychosocial stress: an fMRI study
The interaction of oxytocin and nicotine addiction on psychosocial stress: an fMRI study Open
View article: Photodynamic/photothermal pH-responsive mannose-based dimeric prodrug for synergistic overcoming the biological barriers to conquer multidrug resistance in MRSA
Photodynamic/photothermal pH-responsive mannose-based dimeric prodrug for synergistic overcoming the biological barriers to conquer multidrug resistance in MRSA Open
Methicillin-resistant Staphylococcus aureus (MRSA), recognized for its resistance, poses a formidable challenge to public health, primarily attributable to its biochemical resistant mechanisms, capacity to form protective biofilms, and cap…
View article: The association of back pain with physical inactivity and hypothyroidism in pregnant women
The association of back pain with physical inactivity and hypothyroidism in pregnant women Open
BACKGROUND: During pregnancy, structural and functional changes usually occur in the body, which has various consequences, including lower back pain (LBP) and hypothyroidism. One of the risk factors for these problems is physical inactivit…
View article: Study on the Influence of Defect Clusters Vh-Alk-Vh on Laser Damage Threshold of the Kdp Crystals
Study on the Influence of Defect Clusters Vh-Alk-Vh on Laser Damage Threshold of the Kdp Crystals Open
View article: Photodynamic Cationic Ultrasmall Copper Oxide Nanoparticles-Loaded Liposomes for Alleviation of MRSA Biofilms
Photodynamic Cationic Ultrasmall Copper Oxide Nanoparticles-Loaded Liposomes for Alleviation of MRSA Biofilms Open
Taken together, our findings suggest that photodynamic cationic ultrasmall copper oxide nanoparticles-loaded liposomes are a highly promising nano platform for combating antibiotic-resistant microbial pathogens and biofilms. The effective …
View article: Discovery of 2,4-diphenyl-substituted thiazole derivatives as PRMT1 inhibitors and investigation of their anti-cervical cancer effects
Discovery of 2,4-diphenyl-substituted thiazole derivatives as PRMT1 inhibitors and investigation of their anti-cervical cancer effects Open
View article: In Vivo Study of Biodegradable Pure Magnesium Membrane-Guided Bone Regeneration
In Vivo Study of Biodegradable Pure Magnesium Membrane-Guided Bone Regeneration Open
This study explored the use of a pure magnesium-shielding membrane combined with bone graft materials for repairing vertical bone defects in the mandibular canine.The samples were randomized into three groups, and a vertical box-shaped bon…
View article: The Anti-Multidrug-Resistant Acinetobacter baumannii Study on 1,3-diamino-7H-pyrrolo[3,2-f]quinazoline Compounds
The Anti-Multidrug-Resistant Acinetobacter baumannii Study on 1,3-diamino-7H-pyrrolo[3,2-f]quinazoline Compounds Open
As a major public health problem, the prevalence of Acinetobacter baumannii (A. baumannii) infections in hospitals due to the pathogen’s multiple-antibiotic resistance has attracted extensive attention. We previously reported a series of 1…
View article: Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor
Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor Open
Immune checkpoint inhibitors (ICIs) have successfully treated a number of different types of cancer, which is of great significance for cancer treatment. With the widespread use of ICIs in clinical practice, the increasing checkpoint inhib…
View article: Triclosan Loaded pH-sensitive Vehicles Spray Facilitate Infected Wound Healing by Eliminating Methicillin Resistant Staphylococcus Aureus in Biofilm
Triclosan Loaded pH-sensitive Vehicles Spray Facilitate Infected Wound Healing by Eliminating Methicillin Resistant Staphylococcus Aureus in Biofilm Open
The use of conventional antibiotics has rapidly declined due to the development of antibiotic resistance. Therefore, there is an urgent need for the development of novel vehicles to facilitate effective antibiotics delivery, especially for…
View article: Medical care of rare and undiagnosed diseases: Prospects and challenges
Medical care of rare and undiagnosed diseases: Prospects and challenges Open
Rare and undiagnosed diseases tend to be diverse, misdiagnosed, and difficult to diagnose. In some cases, the disease is progressive and life-threatening. Yet, to date, an estimated 95% of rare diseases have no approved therapy. Therefore,…
View article: Design and Synthesis of Novel PRMT1 Inhibitors and Investigation of Their Effects on the Migration of Cancer Cell
Design and Synthesis of Novel PRMT1 Inhibitors and Investigation of Their Effects on the Migration of Cancer Cell Open
Protein arginine methyltransferase 1 (PRMT1) can catalyze the protein arginine methylation by transferring the methyl group from S-adenosyl-L-methionine (SAM) to the guanidyl nitrogen atom of protein arginine, which influences a variety of…
View article: Smoking related attention alteration in chronic obstructive pulmonary disease-smoking comorbidity
Smoking related attention alteration in chronic obstructive pulmonary disease-smoking comorbidity Open
View article: Towards key scientific questions in the diagnosis and treatment of rare diseases: Summary from the 297th Meeting of the Shuangqing Forum
Towards key scientific questions in the diagnosis and treatment of rare diseases: Summary from the 297th Meeting of the Shuangqing Forum Open
View article: The Enhanced Performance of Ce-Cu/Tio2 Catalyst Synthesized by Ice Melting Method for Selective Catalytic Reduction of Nox with Nh3
The Enhanced Performance of Ce-Cu/Tio2 Catalyst Synthesized by Ice Melting Method for Selective Catalytic Reduction of Nox with Nh3 Open
View article: CCDC 2052960: Experimental Crystal Structure Determination
CCDC 2052960: Experimental Crystal Structure Determination Open
View article: CCDC 2052959: Experimental Crystal Structure Determination
CCDC 2052959: Experimental Crystal Structure Determination Open
View article: The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates
The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates Open