Wenqiang Tang
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View article: Exploring the mechanisms of protective effect of high-energy X-ray FLASH radiotherapy on intestine through multi omics analysis
Exploring the mechanisms of protective effect of high-energy X-ray FLASH radiotherapy on intestine through multi omics analysis Open
Background The aim of this study is to investigate the potential mechanisms underlying the protective effects of high-energy X-ray FLASH radiotherapy (FLASH-RT) on intestine through multi-omics analysis. Methods This study utilized syngene…
View article: Exploring the role of intestinal microbiota in mitigating acute radiation-induced intestinal injury through high-energy X-ray FLASH radiotherapy via metagenomic analysis
Exploring the role of intestinal microbiota in mitigating acute radiation-induced intestinal injury through high-energy X-ray FLASH radiotherapy via metagenomic analysis Open
Objectives This study preliminarily examines the potential correlation between the gut microbiome and the protective effects of FLASH radiotherapy (FLASH-RT) on intestinal tissue using metagenomic analysis. Methods Compact single high-ener…
View article: FLASH Radiation Therapy Using High-Energy x Rays: Validation of the Flash Effect Triggered by a Compact Device
FLASH Radiation Therapy Using High-Energy x Rays: Validation of the Flash Effect Triggered by a Compact Device Open
View article: Integrating network pharmacology, molecular docking, and molecular dynamics simulations to explore potential compounds and mechanisms of <i>Coptis chinensis</i> in treating streptococcal infections
Integrating network pharmacology, molecular docking, and molecular dynamics simulations to explore potential compounds and mechanisms of <i>Coptis chinensis</i> in treating streptococcal infections Open
Background Coptis chinensis , a prominent herb in traditional Chinese medicine, is widely utilized for its therapeutic effects against Streptococcus infections, though its precise mechanisms of action remain insufficiently understood. This…
View article: Risk prediction models for depression in cancer survivors: A systematic review and meta-analysis
Risk prediction models for depression in cancer survivors: A systematic review and meta-analysis Open
Background: To systematically evaluate the risk prediction models for depression in cancer survivors, so as to provide guidance for establishing and improving models. Methods: CNKI, Wanfang Database, Sinmed, PubMed, Web of Science, The Coc…
View article: Characterization and enzymatic function of thioredoxin glutathione reductase in Orientobilharzia turkestanicum isolated from Xizang
Characterization and enzymatic function of thioredoxin glutathione reductase in Orientobilharzia turkestanicum isolated from Xizang Open
View article: Multi-modal radiomics model based on four imaging modalities for predicting pathological complete response to neoadjuvant treatment in breast cancer
Multi-modal radiomics model based on four imaging modalities for predicting pathological complete response to neoadjuvant treatment in breast cancer Open
Objective The radiomics model based on single imaging modality has been demonstrated as a promising approach for predicting the response to neoadjuvant treatment (NAT) in breast cancer. However, whether integrating multiple imaging modalit…
View article: Clinical significance of HER2 overexpression in biliary tract carcinoma ——a meta analysis
Clinical significance of HER2 overexpression in biliary tract carcinoma ——a meta analysis Open
Introduction Previous studies have been inconsistent on the correlation of human epidermal growth factor receptor 2 (HER2) overexpression in biliary tract carcinoma. The objective of this meta analysis was to assess its association with cl…
View article: Sintilimab‑induced acute erosive hemorrhagic gastritis as an adverse reaction of third‑line therapy in a nasopharyngeal carcinoma patient: A case report
Sintilimab‑induced acute erosive hemorrhagic gastritis as an adverse reaction of third‑line therapy in a nasopharyngeal carcinoma patient: A case report Open
Immune checkpoint inhibitors (ICIs) have become an important treatment option for patients with nasopharyngeal carcinoma. With the increasing use of such agents, immune-related adverse events (irAEs) have become a concern. Identifying and …
View article: The influence of beam parameters on FLASH effect
The influence of beam parameters on FLASH effect Open
Ultra-high dose rate radiotherapy (FLASH-RT) is typically defined as an external beam radiotherapy that utilizes a dose rate of 40 Gy/s or higher, compared with conventional dose rate radiotherapy (≤0.1 Gy/s). The primary advantage of FLAS…
View article: Prevalence and Molecular Characterization of Parasitic Lice in Tibetan Yaks, Pigs and Sheep
Prevalence and Molecular Characterization of Parasitic Lice in Tibetan Yaks, Pigs and Sheep Open
The infestation of ectoparasites poses a severe problem in animal breeding, severely affecting animal health and causing substantial economic losses. However, limited information is available regarding lice infestations in plateau livestoc…
View article: Reshaping epigenomic landscapes in facilitating the speciation of bread wheat
Reshaping epigenomic landscapes in facilitating the speciation of bread wheat Open
Summary Polyploidization is a driving force of wheat evolution and speciation, yet its impact on epigenetic regulation and gene expression remains unclear. Here, we constructed a high-resolution epigenetic landscape across leaves, spikes, …
View article: Efficacy and safety of anlotinib combined with S‑1 as a third‑ or later‑line treatment for advanced non‑small cell lung cancer in China: A systematic review and meta‑analysis
Efficacy and safety of anlotinib combined with S‑1 as a third‑ or later‑line treatment for advanced non‑small cell lung cancer in China: A systematic review and meta‑analysis Open
Anlotinib is presently used as a third-line treatment for non-small cell lung cancer. However, it is not yet reported whether combining anlotinib with S-1 as a third- or later-line treatment offers superior outcomes compared with anlotinib…
View article: Rice Varieties Intercropping Induced Soil Metabolic and Microbial Recruiting to Enhance the Rice Blast (Magnaporthe Oryzae) Resistance
Rice Varieties Intercropping Induced Soil Metabolic and Microbial Recruiting to Enhance the Rice Blast (Magnaporthe Oryzae) Resistance Open
[Background] Intercropping is considered an effective approach to defending rice disease. [Objectives/Methods] This study aimed to explore the resistance mechanism of rice intraspecific intercropping by investigating soil metabolites and t…
View article: Changes in the Microbiome in Yak Mastitis: Insights Based on Full-Length 16S rRNA Sequencing
Changes in the Microbiome in Yak Mastitis: Insights Based on Full-Length 16S rRNA Sequencing Open
Mastitis is an inflammation of the mammary gland that can be caused by various factors, including biological, chemical, mechanical, or physical. Microbiological culture, DNA techniques, and high-throughput next-generation sequencing have b…
View article: The impact of metal implants on the dose and clinical outcome of radiotherapy (Review)
The impact of metal implants on the dose and clinical outcome of radiotherapy (Review) Open
Radiotherapy (RT) is one of the most widely used and effective cancer treatments. With the increasing need for organ reconstruction and advancements in material technology, an increasing number of patients with cancer have metallic implant…
View article: Molecular characterization of Cryptosporidium spp. in Bactrian camels (Camelus bactrianus) from Yili Kazak Autonomous Prefecture of Xinjiang, China
Molecular characterization of Cryptosporidium spp. in Bactrian camels (Camelus bactrianus) from Yili Kazak Autonomous Prefecture of Xinjiang, China Open
Introduction Cryptosporidium spp. is a significant zoonotic parasite. The prevalence and infection characteristics of Cryptosporidium spp. in Bactrian camels in Yili Kazak Autonomous Prefecture have yet to be fully understood. Thus, the mo…
View article: Proteomic investigation reveals molecular mechanisms of plant height regulation in foxtail millet
Proteomic investigation reveals molecular mechanisms of plant height regulation in foxtail millet Open
Plant height is an essential characteristic of agronomic traits, and an ideal plant height is essential for high crop yield. Foxtail millet (Setaria italica) has been regarded as a novel diploid C4 model crop. The proteomic profiles of the…
View article: Detection of Parasites in the Field: The Ever-Innovating CRISPR/Cas12a
Detection of Parasites in the Field: The Ever-Innovating CRISPR/Cas12a Open
The rapid and accurate identification of parasites is crucial for prompt therapeutic intervention in parasitosis and effective epidemiological surveillance. For accurate and effective clinical diagnosis, it is imperative to develop a nucle…
View article: Combination of radiotherapy and flap reconstruction for cancer treatments (Review)
Combination of radiotherapy and flap reconstruction for cancer treatments (Review) Open
Flaps are commonly used to repair large tissue defects caused by tumor resection and are often combined with radiotherapy. Relevant explanations for the mechanism underlying the effect of radiotherapy on flaps and the selection of the sequ…
View article: Characterization of the complete mitochondrial genome and phylogenetic analyses of Haemaphysalis tibetensis Hoogstraal, 1965 (Acari: Ixodidae)
Characterization of the complete mitochondrial genome and phylogenetic analyses of Haemaphysalis tibetensis Hoogstraal, 1965 (Acari: Ixodidae) Open
Ticks are specialized ectoparasites that feed on blood, causing physical harm to the host and facilitating pathogen transmission. The genus Haemaphysalis contains vectors for numerous infectious agents. These agents cause various diseases …
View article: Orbital Controls and Threshold Effects on Carbon Isotope Excursions During the Toarcian Oceanic Anoxic Event
Orbital Controls and Threshold Effects on Carbon Isotope Excursions During the Toarcian Oceanic Anoxic Event Open
View article: Detection of Parasites in the Field: The Ever-Innovating CRISPR-Cas12a
Detection of Parasites in the Field: The Ever-Innovating CRISPR-Cas12a Open
The rapid and accurate detection of parasites is crucial for timely curative intervention in parasitosis and for epidemiological surveillance. To meet the needs of clinical diagnosis, it is imperative to develop a diagnostic tool based on …
View article: Characterization of the Complete Mitochondrial Genome and Phylogenetic Analyses of Eurytrema coelomaticum (Trematoda: Dicrocoeliidae)
Characterization of the Complete Mitochondrial Genome and Phylogenetic Analyses of Eurytrema coelomaticum (Trematoda: Dicrocoeliidae) Open
Eurytrema coelomaticum, a pancreatic fluke, is recognized as a causative agent of substantial economic losses in ruminants. This infection, commonly referred to as eurytrematosis, is a significant concern due to its detrimental impact on l…
View article: Key changes in the future clinical application of ultra-high dose rate radiotherapy
Key changes in the future clinical application of ultra-high dose rate radiotherapy Open
Ultra-high dose rate radiotherapy (FLASH-RT) is an external beam radiotherapy strategy that uses an extremely high dose rate (≥40 Gy/s). Compared with conventional dose rate radiotherapy (≤0.1 Gy/s), the main advantage of FLASH-RT is that …
View article: An E2-E3 pair contributes to seed size control in grain crops
An E2-E3 pair contributes to seed size control in grain crops Open
Understanding the molecular mechanisms that regulate grain yield is important for improving agricultural productivity. Protein ubiquitination controls various aspects of plant growth but lacks understanding on how E2-E3 enzyme pairs impact…
View article: Boosting wheat functional genomics via an indexed EMS mutant library of KN9204
Boosting wheat functional genomics via an indexed EMS mutant library of KN9204 Open
A better understanding of wheat functional genomics can improve targeted breeding for better agronomic traits and environmental adaptation. However, the lack of gene-indexed mutants and the low transformation efficiency of wheat limit in-d…
View article: Exosomes: The Role in Tumor Tolerance and the Potential Strategy for Tumor Therapy
Exosomes: The Role in Tumor Tolerance and the Potential Strategy for Tumor Therapy Open
Drug and radiotherapy resistance is the primary cause of treatment failure and poor prognosis in patients with tumors. Exosomes are extracellular vesicles loaded with substances such as nucleic acids, lipids, and proteins that transmit inf…
View article: Genetic diversity and haplotype analysis of yak and sheep echinococcal cysts isolates from the mitochondrial cox1 gene in parts of Tibet, China
Genetic diversity and haplotype analysis of yak and sheep echinococcal cysts isolates from the mitochondrial cox1 gene in parts of Tibet, China Open
Echinococcosis, also known as hydatid disease, is caused by the metacestode stage of the species cluster Echinococcus granulosus sensu lato ( E. granulosus s.l.). It is almost widespread worldwide, especially in countries and regions domin…
View article: Spatial clustering for echinococcosis of Yak in China based on ArcGIS during the past 4 decades
Spatial clustering for echinococcosis of Yak in China based on ArcGIS during the past 4 decades Open
Background: Objective The study on the infection of hydatid disease in yaks in China provides the general epidemiological information of hydatid disease infection in yaks, which is of great value for the formulation of prevention and contr…