Wenru Zhang
YOU?
Author Swipe
View article: Targeting VPS18 hampers retromer trafficking of PD-L1 and augments immunotherapy
Targeting VPS18 hampers retromer trafficking of PD-L1 and augments immunotherapy Open
Immune checkpoint inhibitors targeting programmed cell death 1 (PD-1) or programmed cell death-ligand 1 (PD-L1) have achieved impressive antitumor clinical outcomes. However, the limited response rates suggest the incomplete understanding …
View article: RETRACTED: Relationships between depression level and serum inflammatory factors and thyroxine levels in patients with malignant bone tumors associated with depression
RETRACTED: Relationships between depression level and serum inflammatory factors and thyroxine levels in patients with malignant bone tumors associated with depression Open
Depression degree in patients with malignant bone tumors correlates with serum inflammatory factors and thyroxine levels. Measurement of serum inflammatory factors and thyroxine levels can assess the progression and prognosis of depressed …
View article: Macrophage polarization in the tumor microenvironment: Emerging roles and therapeutic potentials
Macrophage polarization in the tumor microenvironment: Emerging roles and therapeutic potentials Open
The tumor microenvironment (TME) is a combination of tumor cells and indigenous host stroma, which consists of tumor-infiltrating immune cells, endothelial cells, fibroblasts, pericytes, and non-cellular elements. Tumor-associated macropha…
View article: Ligand recognition and activation of neuromedin U receptor 2
Ligand recognition and activation of neuromedin U receptor 2 Open
View article: High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors Open
The global COVID-19 coronavirus pandemic has infected over 109 million people, leading to over 2 million deaths up to date and still lacking of effective drugs for patient treatment. Here, we screened about 1.8 million small molecules agai…
View article: The Genus Broussonetia: An Updated Review of Phytochemistry, Pharmacology and Applications
The Genus Broussonetia: An Updated Review of Phytochemistry, Pharmacology and Applications Open
The Broussonetia genus (Moraceae), recognized for its value in many Chinese traditional herbs, mainly includes Broussonetia papyrifera (L.) L’Hér. ex Vent. (BP), Broussonetia kazinoki Siebold (BK), and Broussonetia luzonica (Blanco) Bureau…
View article: Structural insights into ligand recognition and selectivity of somatostatin receptors
Structural insights into ligand recognition and selectivity of somatostatin receptors Open
View article: Numerical Modeling of Rock Panels Subjected to Blast Loadings
Numerical Modeling of Rock Panels Subjected to Blast Loadings Open
In rock engineering problems, the rock is usually subjected to dynamic loads induced by drill, blast and rockburst. Therefore, understanding the dynamic response of rock benefit the safety and productivity of excavation activities. In this…
View article: Research on Distribution Planning of Electric Vehicle Charging Station Based on Discrete Location Model
Research on Distribution Planning of Electric Vehicle Charging Station Based on Discrete Location Model Open
For both environmental and economic factors, an increasing of countries begins to focus on electric vehicles (EV). As the EV industry continues to evolve, how to establish enough vehicle charging stations in the right locations is a critic…
View article: Research on Data Collection Design Based on Zigbee Wireless Technology Smart Home System
Research on Data Collection Design Based on Zigbee Wireless Technology Smart Home System Open
In order to decrease the shortcomings of traditional smart home control system, we take a new smart home management system by using microprocessor control technology and wireless networking technology. This system uses ARM9 processor as th…
View article: Two disparate ligand-binding sites in the human P2Y1 receptor
Two disparate ligand-binding sites in the human P2Y1 receptor Open
View article: Peripheral adipose tissue insulin resistance alters lipid composition and function of hippocampal synapses
Peripheral adipose tissue insulin resistance alters lipid composition and function of hippocampal synapses Open
Compelling evidence indicates that type 2 diabetes mellitus, insulin resistance ( IR ), and metabolic syndrome are often accompanied by cognitive impairment. However, the mechanistic link between these metabolic abnormalities and CNS dysfu…
View article: Study about the Goal and Key Tasks for the 13th Five-year Transportation Development Planning
Study about the Goal and Key Tasks for the 13th Five-year Transportation Development Planning Open
The paper clears the transportation development direction and the key construction field of the 13th five-year planning, establishs the evaluation system of the main mode of transport capacity in various fields and the evaluation system ar…