Wenwen Huang
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View article: Network Analysis of Autistic Traits in Children with Autism and Their Parents: Validation through Follow-up Data and Eye-Tracking Technology
Network Analysis of Autistic Traits in Children with Autism and Their Parents: Validation through Follow-up Data and Eye-Tracking Technology Open
Owing to the influence of genetic and environmental factors, complex associations exist between autistic traits in children with autism spectrum disorder (ASD) and their parents. However, little is known about the structure and temporal st…
View article: Metabolomics navigates natural variation in pathogen-induced secondary metabolism across soybean cultivar populations
Metabolomics navigates natural variation in pathogen-induced secondary metabolism across soybean cultivar populations Open
Phytophthora soja e-induced root rot poses a major threat to soybean production. While the molecular mechanisms underlying soybean– P. sojae interactions have been extensively studied, their biochemical basis remains largely unexplored. Pr…
View article: An UPLC-MS/MS method for determination of karacoline in mice and its pharmacokinetics study
An UPLC-MS/MS method for determination of karacoline in mice and its pharmacokinetics study Open
In this experiment, ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was employed to quantify karacoline in mouse plasma following both intravenous and oral administration, thereby elucidating the pharmacokinet…
View article: Transmembrane nanogold energy transfer ruler enables <i>in situ</i> synchronized projecting of receptor dimerization–phosphorylation signaling
Transmembrane nanogold energy transfer ruler enables <i>in situ</i> synchronized projecting of receptor dimerization–phosphorylation signaling Open
The T-Nanoruler regulates Met receptor distance (0–8.6 nm) via ss- n -FAM DNA, with G 5 @P-Met detecting phosphorylation levels inversely correlated to spacing by FCM.
View article: Glycosaminoglycans in Tissue Regeneration: Insights Into Glycobiology and Their Biomedical Application
Glycosaminoglycans in Tissue Regeneration: Insights Into Glycobiology and Their Biomedical Application Open
View article: Response of soil biochemical properties and ecosystem function to microplastics pollution
Response of soil biochemical properties and ecosystem function to microplastics pollution Open
Microplastics (MPs)-induced changes in soil nutrient cycling and microbial activity may pose a potential risk to soil ecosystem. Although some studies have explored these topics, there is still a large space for exploration and a relative …
View article: Effects of emodin on the physiological responses and antioxidant gene expression of Wuchang bream infected with <i>Aeromonas hydrophila</i>
Effects of emodin on the physiological responses and antioxidant gene expression of Wuchang bream infected with <i>Aeromonas hydrophila</i> Open
This experiment aimed to investigate the effects of emodin on the physiological responses and antioxidant gene expression of Wuchang bream infected with Aeromonas hydrophila . The experimental diets were prepared with supplementing 0, 30, …
View article: Molecular prevalence, subtype distribution, and zoonotic potential of Blastocystis sp. in wild rodents and shrews inhabiting Zhejiang province of China
Molecular prevalence, subtype distribution, and zoonotic potential of Blastocystis sp. in wild rodents and shrews inhabiting Zhejiang province of China Open
Introduction Globally, rodents and shrew populations constitute crucial elements of diverse environments and animal communities. It is imperative to study their population dynamics to mitigate any potential negative impact on humans, as th…
View article: Hydroxychloroquine improves manifestation of PE rats under oxidative stress by regulating the PI3K/AKT/mTOR signaling pathway to inhibit autophagy
Hydroxychloroquine improves manifestation of PE rats under oxidative stress by regulating the PI3K/AKT/mTOR signaling pathway to inhibit autophagy Open
Preeclampsia is the leading cause of maternal and fetal morbidity and mortality worldwide. Oxidative stress involved in the development of preeclampsia. Hydroxychloroquine, an antimalarial drug, has a variety of drug properties, one of whi…
View article: Factors associated with postoperative efficacy evaluation in patients with morbid obesity
Factors associated with postoperative efficacy evaluation in patients with morbid obesity Open
View article: Comparative proteomics analysis of Shiraia bambusicola revealed a variety of regulatory systems on conidiospore formation
Comparative proteomics analysis of Shiraia bambusicola revealed a variety of regulatory systems on conidiospore formation Open
Shiraia bambusicola is a typical parasitic medicinal fungus of the family Shiraiaceae. The fruiting bodies of S. bambusicola cannot be cultivated artificially, and active substances can be effectively produced via fermentation. The mechani…
View article: Development and validation of a risk assessment model for seizure recurrence during anti-seizure medications withdrawal
Development and validation of a risk assessment model for seizure recurrence during anti-seizure medications withdrawal Open
This study is mainly to develop a risk assessment model for seizure recurrence during anti-seizure medications(ASMs) withdrawal in children and to evaluate and validate the model. Retrospective collection of children with epilepsy from Jan…
View article: Endothelial anthrax toxin receptor 2 plays a protective role in liver fibrosis
Endothelial anthrax toxin receptor 2 plays a protective role in liver fibrosis Open
Hepatocellular carcinoma is one of the leading cancers worldwide and is a potential consequence of fibrosis. Therefore, the identification of key cellular and molecular mechanisms involved in liver fibrosis is an important goal for the dev…
View article: Corrigendum to ’ 5-Aza-dC promotes T-cell acute lymphoblastic leukemia cell invasion via downregulation of DNMT1 and upregulation of MMP-2 and MMP-9’ [Volume 114, October 2022, Pages 43-53.e2]
Corrigendum to ’ 5-Aza-dC promotes T-cell acute lymphoblastic leukemia cell invasion via downregulation of DNMT1 and upregulation of MMP-2 and MMP-9’ [Volume 114, October 2022, Pages 43-53.e2] Open
View article: P1252: THE ROLE OF PALMITOLEIC ACID IN REGULATING INTESTINAL FLORA TO IMPROVE ACUTE GRAFT-VERSUS-HOST DISEASE AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION
P1252: THE ROLE OF PALMITOLEIC ACID IN REGULATING INTESTINAL FLORA TO IMPROVE ACUTE GRAFT-VERSUS-HOST DISEASE AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION Open
Topic: 21. Stem cell transplantation - Experimental Background: Acute graft-versus-host disease (aGVHD) has limited therapeutic options, and thus restricts the development of allogeneic hematopoietic stem-cell transplantation (allo-HSCT). …
View article: TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
View article: Integrated analyses of single-cell transcriptomics identify metastasis-associated myeloid subpopulations in breast cancer lung metastasis
Integrated analyses of single-cell transcriptomics identify metastasis-associated myeloid subpopulations in breast cancer lung metastasis Open
Lung metastasis of breast cancer is closely associated with patient morbidity and mortality, which correlates with myeloid cells in the lung microenvironment. However, the heterogeneity and specificity of metastasis-associated myeloid cell…
View article: Thermal Discharge Temperature Retrieval and Monitoring of NPPs Based on SDGSAT-1 Images
Thermal Discharge Temperature Retrieval and Monitoring of NPPs Based on SDGSAT-1 Images Open
High-accuracy sea surface temperature (SST) retrieval near nuclear power plants (NPPs) is one of the most significant indicators for evaluating marine ecological environment quality, monitoring the real-time situation of thermal discharge,…
View article: Clinicopathological characteristics, local treatment, and prognostic factors in IE/IIE primary breast lymphoma: a retrospective study of 67 patients
Clinicopathological characteristics, local treatment, and prognostic factors in IE/IIE primary breast lymphoma: a retrospective study of 67 patients Open
View article: Update on Chemoresistance Mechanisms to First-Line Chemotherapy for Gallbladder Cancer and Potential Reversal Strategies
Update on Chemoresistance Mechanisms to First-Line Chemotherapy for Gallbladder Cancer and Potential Reversal Strategies Open
Objective: Gallbladder cancer (GBC) mortality remains high and chemoresistance is increasing. This review consolidates what is known about the mechanisms of chemoresistance to inform and accelerate the development of novel GBC-specific che…
View article: Antifungal Activities of a Novel Triazole Fungicide, Mefentrifluconazole, Against the Major Maize Pathogen Fusarium Verticillioides
Antifungal Activities of a Novel Triazole Fungicide, Mefentrifluconazole, Against the Major Maize Pathogen Fusarium Verticillioides Open
View article: Additional file 3 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 3 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 3:ELISA kits information.
View article: Additional file 6 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 6 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 6:(A) qRT-PCR verifies that the mRNA expression of FAP in OEFAP-HFFs is significantly higher than in NCFAP-HFFs and T24 cells. (B, C) WB indicates that the protein expression of FAP in OEFAP-HFFs is significantly higher tha…
View article: Additional file 2 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 2 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 2: Antibodies information of Western blotting.
View article: Additional file 10 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 10 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 10: (A) BLCA with lymphovascular invasion expressed more FAP and VCAN than without lymphovascular invasion. In OS (B) and DSS (C) events, FAP, VCAN, N-cadherin, and Vimentin expression in the deceased group is higher than i…
View article: Additional file 8 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 8 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 8: (A) Immunofluorescence shows that the fluorescence intensity of VCAN in HFFs is markedly enhanced under the induction of TGF-β1; TGF-β1 neutralizing antibody significantly reduces this enhanced fluorescence intensity. (B…
View article: Additional file 4 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 4 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 4:Antibodies information of Immunofluorescence.
View article: Additional file 7 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 7 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 7: (A) VCAN expression is significantly higher in BLCA tissues than in adjacent normal tissues. (B) Immunofluorescence shows that the fluorescence intensity of VCAN in CAFs is notably brighter than in NFs, and in OEFAP-HFFs…
View article: Additional file 1 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 1 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 1: Primer sequences of quantitative real-time.
View article: Additional file 5 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 5 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells Open
Additional file 5:Antibodies information of Immunochemistry.