Explanipedia

In-plane waveguide optical orbital angular momentum mode generators using subwavelength metamaterials Open

Yanxia Zhang, Bojian Shi, Xiaoxin Li, Yanyu Gao, Wenya Gao , et al. · 2025

Optical orbital angular momentum (OAM) beams have gained significant attention for their potential to enhance the transmission capacity of optical communication systems, in which OAM generators play a critical role. Traditionally, light fi…

Efficient coupling of topological photonic crystal waveguides based on transverse spin matching mechanism Open

Bojian Shi, Qi Jia, Xiaoxin Li, Yanxia Zhang, Hang Li , et al. · 2025

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response (Adv. Sci. 15/2025) Open

Ninan Zhang, Ruifan Lin, Wenya Gao, Honglin Xu, Yuejia Li , et al. · 2025

Curcuma aromatica This frontispiece features Curcuma aromatica (Yu Jin), a traditional Chinese medicine used for over 2000 years in China to treat epilepsy and other diseases. In article number 2405263, Wenxiang Meng, Qi Xie, and co‐worker…

Diffractive Metasurface‐Enabled Single‐Shot Characterization of Hybrid‐Order Poincaré Beams Open

Xiaoxin Li, Bojian Shi, Qi Jia, Yanxia Zhang, Yanyu Gao , et al. · 2025

Hybrid‐order Poincaré beams (HyOPBs) with complex transverse polarization states hold significant potential in optical communication and quantum information. Fully characterizing the Poincaré parameters of HyOPBs is a key task to accelerat…

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response Open

Ninan Zhang, Ruifan Lin, Wenya Gao, Honglin Xu, Yuejia Li , et al. · 2025

Neuroinflammation is often characterized by an overactive microglial response. Curcumin, known for its anti‐inflammatory and antioxidant properties, can mitigate microglial hyperactivity following epileptic seizures. The study delves into …

Jianwei Xiaoshi oral liquid attenuates high-calorie diet-induced dyspepsia in immature rats via regulating the pancreatic secretion pathway and maintaining the homeostasis of intestinal microbiota Open

Yan Zhang, Xiaolu Wei, Shan Jiang, Wenya Gao, Kun Wang , et al. · 2025

Background Jianwei Xiaoshi oral liquid (JWXS), a classical traditional prescription comprising various edible medicinal plants, has demonstrated significant efficacy in treating paediatric indigestion. It originates from Jianpi Pill, which…

Bilayer Metasurface-Enabled High Sensitivity Near-Infrared Computational Spectrometer Open

Juntong Chen, Xiaoxin Li, Bojian Shi, Qi Jia, Yanxia Zhang , et al. · 2025

Intestinal endogenous metabolites affect neuroinflammation in 5×FAD mice by mediating “gut-brain” axis and the intervention with Chinese Medicine Open

Xinru Gu, Miao-Xuan Fan, Yanyan Zhou, Yan Zhang, Linna Wang , et al. · 2024

Ultra-Compact Reflective Waveguide Mode Converter Based on Slanted-Surface and Subwavelength Metamaterials Open

Yanxia Zhang, Rui Feng, Bojian Shi, Xiaoxin Li, Yanyu Gao , et al. · 2024

Mode converter (MC) is an indispensable element in the mode multiplexing and demultiplexing system. Most previously reported mode converters have been of the transmission type, while reflective mode converters are significantly lacking. In…

Integrated Phytochemical Analysis Based on Ultra-high-performance Liquid Chromatography-mass Spectrometry and Network Pharmacology Approaches to Explore the Bioactive Constituents and Potential Targets of Jiangtang Qingre Formula Open

Wenya Gao, Yan Zhang, Lijuan Zhou, Min Li, Tao Li , et al. · 2024

Objective: This study aims to elucidate and quantify the composition of Jiangtang Qingre formula (JQF), delineate the absorbed components in the bloodstream, predict the major biologically active components, and identify potential targets …

Simultaneous sorting of arbitrary vector structured beams with spin-multiplexed diffractive metasurfaces Open

Xiaoxin Li, Rui Feng, Fangkui Sun, Yanxia Zhang, Qi Jia , et al. · 2024

Vector structured beams (VSBs) offer infinite eigenstates and open up new possibilities for high-capacity optical and quantum communications by the multiplexing of the states. Therefore, the sorting and measuring of VSBs are extremely impo…

The Protective Effects of Acteoside and Total Glycosides of the Leaves of Rehmannia on Three Types of Glomerular Structural Cells Under High Glucose and Inflammatory Stimulation Open

Yuyang Liu, Wenya Gao, Mengxiao Wang, Baolin Bian, Yanyan Zhou , et al. · 2024

Background: The challenge of chronic glomerulonephritis necessitates innovative strategies for preventing renal function deterioration. Acteoside (ACT), the primary bioactive compound of total glycosides of the leaves of Rehmannia (DHYZG),…

Engineering the electronic structure of sub-nanometric Ru clusters <i>via</i> Pt single-atom modification for highly efficient electrocatalytic hydrogen evolution Open

Yuzhuang Song, Yaowen Zhang, Wenya Gao, Chengzhong Yu, Jun Xing , et al. · 2024

We report herein an environmentally friendly and pyrolysis-free synthesis strategy to prepare an efficient supported catalyst with Pt single-atom modified sub-nanometric Ru clusters for all-pH HER.

Stable Acoustic Pulling in Two-Dimensional Phononic Crystal Waveguides Based on Mode Manipulation Open

Yanyu Gao, Yongyin Cao, Tongtong Zhu, Donghua Tang, Bojian Shi , et al. · 2023

Acoustic manipulation is a set of versatile platforms with excellent manipulation capabilities. In recent years, researchers have increasingly achieved specific manipulations beyond the translation and capture of particles. Here, we focus …

Superimposition of topological charges between vortex beams and singular points of photonic crystal slabs Open

Wenya Gao, Ziyi Liu, Xiangning Li, Xu Wang, Guanqu Hu , et al. · 2023

The bound state in the continuum (BIC) is a singular point of polarization in the momentum space of a periodic structure. It has been demonstrated that vortex beams can be generated by utilizing the polarization vortex around BIC based on …

Arenobufagin-loaded PEG-PLA nanoparticles for reducing toxicity and enhancing cancer therapy Open

Jia-Ying Yang, Bo Sun, Xiaolu Wei, Yanyan Zhou, Wang Hong-jie , et al. · 2023

Arenobufagin (ArBu) is a natural anticancer drug with good anti-tumor effects, but its clinical applications and drug development potential are limited due to its toxicity. The purpose of this study is to reduce the toxic side effects of A…

Bound states in the continuum in asymmetric one-dimensional photonic crystal systems guided by anisotropy Open

Ziyi Liu, Xiangning Li, Chen Chen, Xu Wang, Wenya Gao , et al. · 2023

Bound states in the continuum (BICs) have been widely observed in many symmetric geometries in the optical system during the last decade. Here, we consider a scenario in which the structure is designed asymmetrically with anisotropic biref…

Design and Implementation of High Sensitivity Microwave Radiometer Open

Jie Liu, Ruiqi Zhang, Guangmin Sun, Yuxuan Zhu, Wenya Gao , et al. · 2023

Study on the Mechanism of Chinese Classical Formula Qingxin Lianzi Yin Decoction on Diabetic Nephropathy Based on Network Pharmacology and Metabolomics Open

Wenya Gao, Mengyao Tian, Mingli Li, Shuangrong Gao, Yanyan Zhou , et al. · 2023

Altered Metabolic Profiles and Targets Relevant to the Protective Effect of Acteoside on Diabetic Nephropathy in Db/Db Mice Based on Metabolomics and Network Pharmacology Studies Open

Wenya Gao, Yan Zhang, Shuangrong Gao, Yanyan Zhou, Mengxiao Wang , et al. · 2023

Intestinal endogenous metabolites affect neuroinflammation in 5 ×FAD mice by mediating "gut-brain" axis and the intervention with Chinese Medicine Open

Xinru Gu, Yanyan Zhou, Yan Zhang, Linna Wang, Wenya Gao , et al. · 2022

Emerging evidence suggested the association between gut dysbiosis and Alzheimer’s disease (AD) progression. However, it remains unclear how the gut microbiome and neuroinflammation in the brain mutually interact or how these interactions a…

An integrative analysis of Qingfei Paidu Decoction for its anti-HCoV-229E mechanism in cold and damp environment based on the pharmacokinetics, metabolomics and molecular docking technology Open

Yan Zhang, Xinru Gu, Yanyan Zhou, Nan Si, Wenya Gao , et al. · 2022

A multi-network comparative analysis of whole-transcriptome and translatome reveals the effect of high-fat diet on APP/PS1 mice and the intervention with Chinese medicine Open

Wenya Gao, Junyi Zhou, Xinru Gu, Yanyan Zhou, Linna Wang , et al. · 2022

Different studies on the effects of high-fat diet (HFD) on Alzheimer’s disease (AD) pathology have reported conflicting findings. Our previous studies showed HFD could moderate neuroinflammation and had no significant effect on amyloid-β l…

Cardioprotection effect of Yiqi–Huoxue–Jiangzhuo formula in a chronic kidney disease mouse model associated with gut microbiota modulation and NLRP3 inflammasome inhibition Open

Tong‐Tong Liu, Xiaoguang Lu, Wenya Gao, Yuanyuan Zhai, Han Li , et al. · 2022

Treatment with YHJF effectively protected the heart function of 5/6 Nx mice; this effect was attributed to inhibition of NLRP3 inflammasome activation and regulation of intestinal microbial composition and derived metabolites. YHJF has pot…

The Comprehensive Investigation of Panax Notoginseng Quality Assessment Under the Guidance of Traditional Grading Experience Using Untargeted Metabolomics and Anti-Myocardial Ischemia Activity of Zebrafish Open

Mingli Li, Wenya Gao, Huijun Wang, Jiaying Yang, Yong Zhang , et al. · 2022

MicroRNA-2187 Modulates the NF-κB and IRF3 Pathway in Teleost Fish by Targeting TRAF6 Open

Wenya Gao, Renjie Chang, Yuena Sun, Tianjun Xu · 2021

The innate immune organs and cells detect the invasion of pathogenic microorganisms, which trigger the innate immune response. A proper immune response can protect the organisms from pathogen invasion. However, excessive immunity can destr…

Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer’s disease progression based on the “brain-gut” axis through multiple integrated omics Open

Xinru Gu, Junyi Zhou, Yanyan Zhou, Hongjie Wang, Nan Si , et al. · 2021

Background In recent years, excellent results have suggested an association between the “brain-gut” axis and Alzheimer’s disease (AD) progression, yet the role of the “brain-gut” axis in AD pathogenesis still remains obscure. Herein, we pr…

Circular RNA circPIKfyve Acts as a Sponge of miR-21-3p To Enhance Antiviral Immunity through Regulation of MAVS in Teleost Fish Open

Hui Su, Qing Chu, Weiwei Zheng, Renjie Chang, Wenya Gao , et al. · 2021

Here, we identified a novel circRNA, namely, circPIKfyve, that can act as a key regulator of the innate immune response in teleost fish. circPIKfyve acts as a molecular sponge by competitive adsorbing of miR-21-3p, thereby increasing the a…

A Highly Conserved Circular RNA, circRasGEF1B, Enhances Antiviral Immunity by Regulating the miR-21-3p/MITA Pathway in Lower Vertebrates Open

Qing Chu, Weiwei Zheng, Hui Su, Lei Zhang, Renjie Chang , et al. · 2021

Siniperca chuatsi rhabdovirus (SCRV) is a typical fish RNA rhabdovirus, which is one of the most significant viral pathogens in teleost fish and can cause severe hemorrhagic septicemia in freshwater and marine fishes. Here, we discovered a…

Additional file 2 of Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer’s disease progression based on the “brain-gut” axis through multiple integrated omics Open

Xinru Gu, Junyi Zhou, Yanyan Zhou, Hongjie Wang, Nan Si , et al. · 2021

Additional file 2: Table S1. Levels and ratios of Bile acids measured in the Tg mice (n = 5). Table S2. Peak areas of three main compounds in HLJDD. Table S3. The selected detecting ions, Declustering potential (DP), and collision energy (…

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