Explanipedia

A dual-triggered re-crosslinkable preformed particle gels (RC-PPGs) for enhanced fracture plugging in fractured low-permeability reservoirs Open

Zhilin Sun, Wenyu Cui, Li Chen, Bai Wang, Jianjun Cao , et al. · 2025

Experience-induced NPAS4 reduces dendritic inhibition from CCK+ inhibitory neurons and enhances plasticity Open

Daniel A Heinz, Wenyu Cui, Kimberly L. Cooper, Brenda L. Bloodgood · 2025

How does an inducible transcription factor affect neuronal and circuit function? Here we show that housing mice in an enriched environment induces NPAS4 expression in CA1 pyramidal neurons, leading to a reduction in dendritic inhibition sp…

Biotinylated fusion protein-streptavidin-peroxidase complex based non-competitive magnetic immunoassay for rapid detection of organophosphorus pesticides Open

Ruirui Shi, J LI, Wen‐Li Yu, Tengfei Yin, Haiyan Lin , et al. · 2025

Cyclic cell-penetrating peptide-engineered ceria nanoparticles for non-invasive alleviation of ultraviolet radiation-induced cataract Open

Luyang Jiang, Jinxia Liu, Silong Chen, Wenyu Cui, Jiarui Guo , et al. · 2025

Oxidative stress, which results from the accumulation of free radicals, plays a substantial role in cataract formation. Antioxidants have shown promise in mitigating or even preventing this process. However, delivering antioxidants noninva…

Think on your feet: Seamless Transition between Human-like Locomotion in Response to Changing Commands Open

Huaxing Huang, Wenyu Cui, Tonghe Zhang, Shengtao Li, J. L. Han , et al. · 2025

While it is relatively easier to train humanoid robots to mimic specific locomotion skills, it is more challenging to learn from various motions and adhere to continuously changing commands. These robots must accurately track motion instru…

Individual connectivity-based parcellations reflect functional properties of human auditory cortex Open

Maria Hakonen, Louisa Dahmani, Kaisu Lankinen, Jianxun Ren, Julianna Barbaro , et al. · 2025

Neuroimaging studies of the functional organization of human auditory cortex have focused on group-level analyses to identify tendencies that represent the typical brain. Here, we mapped auditory areas of the human superior temporal cortex…

Diammonium Hydrogen Citrate-Assisted Spray Pyrolysis Synthesis of Nanostructured LiCoPO4 Microspheres as High-Voltage Cathode Material for Lithium-Ion Batteries Open

Ayaulym Belgibayeva, Takeru Nagashima, Wenyu Cui, Daiki Sueyoshi, Izumi Taniguchi · 2024

Nanostructured LiCoPO₄ (LCP) microspheres were successfully synthesized by one-step spray pyrolysis, adding an appropriate amount of diammonium hydrogen citrate (DHC) additive to the precursor solution. Comprehensive physical ch…

Vertical MSM-type CsPbBr3 thin film photodetectors with fast response speed and low dark current Open

Xueming Cheng, Wenyu Cui, L. Y. Zhu, Xia Wang, Zongming Liu , et al. · 2024

Halide perovskites exhibit excellent electrical and optical properties and are ideal candidates for active layers in optoelectronic devices, especially in the field of high-performance photodetection, where they demonstrate a competitive a…

Polymerization Behavior and Rheological Properties of a Surfactant-Modified Reactive Hydrophobic Monomer Open

Xin Wen, Lei Wang, Xiaojuan Lai, Guiru Liu, Wenwen Yang , et al. · 2023

The structures and properties of hydrophobic association polymers can be controlled using micelles. In this work, we synthesize a reactive hydrophobic surfactant monomer, KS-3, from oleic acid, N,N-dimethylpropylenediamine, and allyl chlor…

A 3D‐Printed Dual Driving Forces Scaffold with Self‐Promoted Cell Absorption for Spinal Cord Injury Repair Open

Chen Qiu, Yuan Sun, Jinying Li, Jiayi Zhou, Yuchen Xu , et al. · 2023

Stem cells play critical roles in cell therapies and tissue engineering for nerve repair. However, achieving effective delivery of high cell density remains a challenge. Here, a novel cell delivery platform termed the hyper expansion scaff…

The Impact of mNGS Technology in the Etiological Diagnosis of Severe Pneumonia in Children During the Epidemic of COVID-19 Open

Changjiang Yu, Wei Guo, Zhulai Zhang, Yuting Ma, Xiaobei Cao , et al. · 2023

Compared with traditional methods, mNGS has a higher etiological detection rate and can comprehensively detect various pathogens of severe pneumonia. Therefore, mNGS of bronchoalveolar lavage fluid should be performed in children with seve…

MAPK4 silencing in gastric cancer drives liver metastasis by positive feedback between cancer cells and macrophages Open

Shuang Li, Dongyang Guo, Qiang Sun, Lu Zhang, Yun Cui , et al. · 2023

Liver metastasis is a major cause of death in gastric cancer patients, but the underlying mechanisms are poorly understood. Through a combination of in vivo screening and transcriptome profiling followed by quantitative RT-PCR and tissue a…

Repair of Retinal Degeneration by Human Amniotic Epithelial Stem Cell–Derived Photoreceptor–like Cells Open

Jinying Li, Chen Qiu, Jiayi Zhou, Yang Wei, Weixin Yuan , et al. · 2022

The loss of photoreceptors is a major event of retinal degeneration that accounts for most cases of untreatable blindness globally. To date, there are no efficient therapeutic approaches to treat this condition. In the present study, we ai…

One-pot preparation of nano-scaled magnetic-pectin particles (Fe3O4@pectin NPs): cytotoxicity, antioxidant, and anti-liver cancer properties Open

Qiao Zhang, Wenyu Cui, Honglin Guo, Baoqing Wang, He Wang , et al. · 2022

This work described the one-pot synthesis of orange pectin encapsulated Fe3O4 nanoparticles (Fe3O4@Pectin NPs) which is prepared by co-precipitation of Fe(II/(III) ions in alkaline solution mediated by pectin. This process led to formation…

Human Amniotic Epithelial Stem Cell-Derived Retinal Pigment Epithelium Cells Repair Retinal Degeneration Open

Jinying Li, Chen Qiu, Yang Wei, Weixin Yuan, Jia Liu , et al. · 2021

Age-related macular degeneration (AMD), featured with dysfunction and loss of retinal pigment epithelium (RPE), is lacking efficient therapeutic approaches. According to our previous studies, human amniotic epithelial stem cells (hAESCs) m…

Circ_0004018 suppresses cell proliferation and migration in hepatocellular carcinoma via miR-1197/PTEN/PI3K/AKT signaling pathway Open

He Wang, Qiao Zhang, Wenyu Cui, Wenlan Li, Jimei Zhang · 2021

Hepatocellular carcinoma (HCC) is a common type of primary liver cancer. Circular RNAs (circRNAs) have been demonstrated to be a crucial player in multiple cancers. However, a large number of circRNAs remain to be explored. Our study focus…

Screening‐based identification of xanthone as a novel NLRP3 inflammasome inhibitor via metabolic reprogramming Open

Wenyu Cui, Sheng Chen, Zhexu Chi, Xingchen Guo, Xiaobo Zhang , et al. · 2021

The NLRP3 inflammasome is an intracellular surveillance multimolecule platform that senses broad ranges of pathogen-derived, environmental, and endogenous stress-induced factors,1 and aberrant NLRP3 inflammasome activation is associated wi…

Enhanced expression of miR-889 forecasts an unfavorable prognosis and facilitates cell progression in hepatocellular carcinoma Open

He Wang, Huiwen Wang, Wenyu Cui, Qiao Zhang, Jing Li , et al. · 2021

Circ_0004018 suppresses cell proliferation and migration in hepatocellular carcinoma via miR-1197/PTEN/PI3K/AKT signaling pathway Open

He Wang, Qiao Zhang, Wenyu Cui, Wenlan Li, Jimei Zhang · 2021

Hepatocellular carcinoma (HCC) is a common type of primary liver cancer. Circular RNAs (circRNAs) have been demonstrated to be a crucial player in multiple cancers. However, a large number of circRNAs remain to be explored. Our study focus…

Adjacency effect correction of optical satellite image with sub-meter spatial resolution Open

Tao Wang, Nan Zhou, Weining Yi, Jin Hong, Xiao Liu , et al. · 2021

The adjacency effect, the contribution of the neighboring pixels to the radiance of the line of sight pixel, is caused by the Rayleigh scattering of atmospheric molecules and Mie scattering of aerosol particles. The adjacency effect will c…

Judicious use of low-dosage corticosteroids for non-severe COVID-19: A case report Open

Jian Zhang, Zigang Tian, Lina Feng, Zhongming Yang, Bo Zou , et al. · 2021

Inflammation-mediated lung injury in severe cases of infection with SARS-CoV-2, the aetiological agent of Coronavirus disease 2019 (COVID-19), can lead to respiratory failure and death, and therapies that block or ameliorate lung injury-as…

Sex differences in patients with COVID-19: a retrospective cohort study and meta-analysis Open

Zhijun Li, Lina Feng, Wenyu Cui, Jian Zhang, Yingxin Huang , et al. · 2020

BACKGROUND: Accumulated evidence revealed that male was much more likely to higher severity and fatality by SARS-CoV-2 infection than female patients, but few studies and meta-analyses have evaluated the sex differences of the infection an…

Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3 Open

Jian Li, Lijun Yan, Jianghan Luo, Tong Li, Yuan Gao , et al. · 2020

Exploring key genes associated with non-small cell lung carcinoma (NSCLC) may lead to targeted therapies for NSCLC patients. The protein kinase MAP4K3 has been established as an important modulator of cell growth and autophagy in mammals. …

Human Amniotic Epithelial Stem Cells: A Promising Seed Cell for Clinical Applications Open

Chen Qiu, Zhen Ge, Wenyu Cui, Luyang Yu, Jinying Li · 2020

Perinatal stem cells have been regarded as an attractive and available cell source for medical research and clinical trials in recent years. Multiple stem cell types have been identified in the human placenta. Recent advances in knowledge …

The epidemiology and association rules of concurrent pulmonary tuberculosis and extrapulmonary tuberculosis (PTB-EPTB) in China: a large-scale multi- center observational study Open

Wanli Kang, Jian Du, Yunqing Chang, Hongyan Chen, Jianxiong Liu , et al. · 2020

Background Tuberculosis (TB) is a multi-systemic disease with a protean presentation and remains a major global health problem. Concurrent pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) are common in clinical practice.…

Upregulation of BCAM and its sense lncRNA BAN are associated with gastric cancer metastasis and poor prognosis Open

Juan Jin, Shanshan Xie, Qiang Sun, Huang Zhenxia, Kang‐Hua Chen , et al. · 2020

Patients with metastatic gastric cancer (GC) have a poor prognosis; however, the molecular mechanism of GC metastasis remains unclear. Here, we employed bioinformatics to systematically screen the metastasis‐associated genes and found that…

Emerging roles of lncRNA in cancer and therapeutic opportunities. Open

Mingchun Jiang, Jiaojiao Ni, Wenyu Cui, Boya Wang, Wei Zhuo · 2019

Cancer is difficult to cure due to frequent metastasis, and developing effective therapeutic approaches to treat cancer is urgently important. Long non-coding RNAs (lncRNAs) have diverse roles in regulating gene expression at both the tran…

Pharmacological evidence: a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells Open

Shang Wang, Chao-Liang Long, Jun Chen, Wenyu Cui, Yanfang Zhang , et al. · 2016

Differential modulation of GABAA and NMDA receptors by α7-nicotinic receptor desensitization in cultured rat hippocampal neurons Open

Lei Shen, Wenyu Cui, Ruzhu Chen, Hai Wang · 2016

Sensitivity of KATP channels to cellular metabolic disorders and the underlying structural basis Open

Chun-gang Li, Wenyu Cui, Hai Wang · 2016

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