Explanipedia

Low-Velocity Impact Response of a Protection Plate with a Composite Asymmetrical Sandwich Structure: Models and Experiments Open

Fengqiang Zhang, Jun Zhou, Yinghai Jin, Yu Wang, Weiliang Liao · 2025

This study examines the response of a composite material protection plate with an asymmetrical sandwich structure under low-velocity impact. The protection plate with an asymmetrical sandwich structure is constructed with materials such as…

Efficacy and Safety of Direct Oral Anticoagulants versus Standard Anticoagulation for Thromboprophylaxis in Nephrotic Syndrome: A Systematic Review and Meta-analysis. Open

Lihua Shi, Xiaoying Zhang, Congyao Wang, Yu Wang · 2025

Author Correction: Histone tyrosine sulfation by SULT1B1 regulates H4R3me2a and gene transcription Open

Weixing Yu, Runxin Zhou, Nan Li, Zhi‐Chao Lei, Dingyuan Guo , et al. · 2025

Research progress on natural plant metabolites targeting apoptosis for endometriosis prevention and treatment: a systematic review Open

Yang Yu, Yufei Zhu, Mengyao Gao, Yu Wang, Shiying Li , et al. · 2025

Endometriosis (EMs) is a prevalent benign gynecological disorder characterized by dysmenorrhea and infertility, significantly impacting women’s health and quality of life. Currently, the pathogenesis of EMs remains incompletely elucidated.…

Research on the Impact Resistance of Sandwich-Structured Battery Pack Protective Plates Open

Jun Zhou, Changjie Luo, Ruilin Shen, Fengqiang Zhang, Yu Wang , et al. · 2025

With the continuous development of the new energy vehicle industry, in order to further improve the safety and range of electric vehicles, vehicle lightweighting has been a key focus of major car companies. However, research on lightweight…

Effects of Simiao Pill on rheumatoid arthritis complicated with interstitial lung disease via the ATX/LPA/LPA1 and RhoA/ROCK2 signaling pathways Open

Jiahui Yan, Liang Han, Xin Ba, Pan Shen, Weiji Lin , et al. · 2025

Background: In Traditional Chinese Medicine theory, Simiao Pill represents a traditional herbal formulation used for rheumatoid arthritis (RA) management. Initial research indicates that Simiao Pill might have therapeutic benefits for RA l…

Multi-omics analyses unveil dual genetic loci governing four distinct watermelon flesh color phenotypes Open

Na Li, Shilai Xing, Gaofei Sun, Jianli Shang, Jia‐Long Yao , et al. · 2025

Watermelon fruit flesh displays various colors. Although genetic loci underlying these variations are identified, the molecular mechanism remains elusive. Here, we assembled a chromosome-scale reference genome of an elite watermelon and de…

Breathable core–shell microneedle patches for diabetic wound treatment Open

Lu Fan, Yu Wang, Li Wang, Xiang Lin, Xiaoju Wang , et al. · 2025

Microneedles have demonstrated valuable applications in diabetic wound management. Many endeavors are devoted to developing microneedles with well-designed structures and enhanced functions. Herein, we present an elaborate microneedle patc…

Bidirectional causal association between type 1 diabetes and autoimmune diseases: a Mendelian randomization study Open

Liang Han, Youpeng Su, Hua Huang, Jiahui Yan, Tingting Li , et al. · 2025

Introduction It has been reported that individuals with type 1 diabetes (T1D) are at a higher risk of concomitant occurrence of other autoimmune diseases (AIDs). Currently, there is a lack of research investigating the causal relationship …

A case of collagenous gastritis: endoscopic and endocytoscopic features Open

Yu Wang, Heng Zhang, Xi Chen · 2025

Multiparameter diagnostic model using S100A9, CCL5 and blood biomarkers for nasopharyngeal carcinoma Open

Lu Long, Ya Tao, Yu Wang, Qizhuo Hou, Yunlai Liang , et al. · 2025

Dual physiological responsive structural color hydrogel particles for wound repair Open

Li Wang, Lu Fan, Anne M. Filppula, Yu Wang, Feika Bian , et al. · 2025

Hydrogel-based patches have demonstrated their values in diabetic wounds repair, particularly those intelligent dressings with continuous repair promoting and monitoring capabilities. Here, we propose a type of dual physiological responsiv…

Neutrophil extracellular traps promote MASH fibrosis by metabolic reprogramming of HSC Open

Yujia Xia, Yu Wang, Qi Xiong, Jiayi He, Han Wang , et al. · 2024

Background and Aims: Metabolic dysfunction–associated steatohepatitis (MASH) fibrosis is a reversible stage of liver disease accompanied by inflammatory cell infiltration. Neutrophils extrude a meshwork of chromatin fibers to establish neu…

Antibiotic Resistance Genes are Transferred from Manure-Improved Water Bodies to the Gut Microbiota of Animals in the Food Chain Open

Ce Wang, Yuzi Song, Jingxuan Liang, Yu Wang, Di Zhang , et al. · 2024

The 5-HT1a  Receptor Mediates the Anxiolytic-Like Effects Of Cannabidiol But Does Not Mediate its Effects on the Negative Symptoms of Schizophrenia In Mice Models Open

Guangzhao Shu, Jingshan Shen, He Yang, Jin Suo, Chunhui Wu , et al. · 2024

Author Correction: Histone tyrosine sulfation by SULT1B1 regulates H4R3me2a and gene transcription Open

Weixing Yu, Runxin Zhou, Nan Li, Zhi‐Chao Lei, Dingyuan Guo , et al. · 2023

Merchant Guild Culture and Cash Holdings: Evidence from China Open

Yu Wang, Sophia Chao · 2023

Phosphomolybdic Acid Clusters and Carbon Nitride Coloading on Nh2-N-Rgo for Photocatalytic Oxidation Desulfurization Open

Lei Wang, zehui hu, chenchen deng, Yu Wang, guoxian ma , et al. · 2023

N6-Methyladenosine Regulators Promote Malignant Progression of Gastric Adenocarcinoma Open

Yibin Zhao, Xiao Yan, Yu Wang, Juan Zhou, Yu Yang · 2022

N6-methyladenosine (m6A) RNA methylation is dynamically and reversibly regulated by methyltransferases, binding proteins, and demethylases. The restoration of m6A to adenosine could result in demethylation modifications. Abnormalities in m…

The novel circular RNA HIPK3 accelerates the proliferation and invasion of hepatocellular carcinoma cells by sponging the micro RNA-124 or micro RNA-506/pyruvate dehydrogenase kinase 2 axis Open

Qiangfeng Yu, Wen-Xiang Chen, Yiming Li, Jun He, Yu Wang , et al. · 2022

Circular RNAs (circRNAs) have been confirmed to be associated with the progression of various cancers, including hepatocellular carcinoma (HCC). However, the role and mechanism of circHIPK3 in HCC are still unclear. To investigate its func…

Lansoprazole-induced osteoporosis via the IP3R- and SOCE-mediated calcium signaling pathways Open

Ziping Cheng, Yangjie Liu, Mengyuan Ma, Shiyu Sun, Zengqing Ma , et al. · 2022

Programmable Hybridization Assemble Nicked Displacement Amplification for Detecting Ricin Toxin Open

Yu Wang, Peng Yuan, Jialei Bai, Shuang Li, Dianpeng Han , et al. · 2022

Neutrophils Extracellular Traps Inhibition Improves PD-1 Blockade Immunotherapy in Colorectal Cancer Open

Hongji Zhang, Yu Wang, Amblessed E. Onuma, Jiayi He, Han Wang , et al. · 2021

Immune checkpoint inhibitors can improve the prognosis of patients with advanced malignancy; however, only a small subset of advanced colorectal cancer patients in microsatellite-instability-high or mismatch-repair-deficient colorectal can…

Corrigendum: Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting the PI3K–AKT Pathway and Activating the AMPK–ROS Pathway Open

Xuan Wei, Juanjuan Shi, Qianhan Lin, Xiaoxue Ma, Yingxin Pang , et al. · 2021

Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting the PI3K-AKT Pathway and Activating the AMPK-ROS Pathway [email protected] the original article, there was a mistake in "FIGURE 5B" a…

Pre-operative exercise therapy triggers anti-inflammatory trained immunity of Kupffer cells through metabolic reprogramming Open

Hongji Zhang, Tianmeng Chen, Jinghua Ren, Yujia Xia, Amblessed E. Onuma , et al. · 2021

Functional Polymorphism in the NFE2L2 Gene Associated With Tuberculosis Susceptibility Open

Guiyi Ji, Miaomiao Zhang, Qianqian Liu, Shouquan Wu, Yu Wang , et al. · 2021

Background Nuclear transcription factor erythroid 2 p45-related factor 2 (Nrf2), encoded by NFE2L2 , functions as a key transcription factor and regulates expression of antioxidant genes. Our study aimed to investigate the association of s…

Pharmacokinetics of Levornidazole Tablet in Healthy Chinese Subjects and Proposed Dosing Regimen Based on Pharmacokinetic/Pharmacodynamic Analysis Open

Hailan Wu, Zhiqiang Wang, Yu Wang, Jicheng Yu, Yaxin Fan , et al. · 2021

Trial registration number CTR20160786 at http://www.chinadrugtrials.org.cn/ .

Circulating microRNAs as candidate biomarkers for the ovarian response during in vitro fertilization Open

Hongjuan Zhao, Liyan Wang, Yu Wang · 2021

MicroRNAs (miRNAs) in the let-7 family have established regulatory roles in pregnancy; in this study, we evaluated whether miRNAs detectable in the circulation are associated with the ovarian response to stimulation. In total, 25 patients …

Si Miao San Attenuates Inflammation and Oxidative Stress in Rats with CIA via the Modulation of the Nrf2/ARE/PTEN Pathway Open

Pan Shen, Yao Huang, Xin Ba, Weiji Lin, Kai Qin , et al. · 2021

Objective. Si Miao San (SMS) is a traditional Chinese formula used in China to treat rheumatic diseases. To date, its mechanism in rheumatoid arthritis (RA) treatment is uncertain. Our study aims to assess the antiarthritic effects of SMS …

Nursing management in allogeneic hematopoietic stem cell transplantation for children with Fanconi anemia Open

Yu Wang, Xiaolin LIU, Le LIN, Ling JI, Le Zhang , et al. · 2021

This paper reviewed the clinical data of 15 children undergoing allogeneic hematopoietic stem cell transplantation (HSCT) for Fanconi anemia. All the children received comprehensive nursing measures including overall environmental protecti…

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