Wenzheng Chen
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View article: MK8722 alleviates osteoarthritis by activating Sesn2 and transcriptionally upregulating BNIP3 to promote mitophagy and inhibit chondrocyte ferroptosis
MK8722 alleviates osteoarthritis by activating Sesn2 and transcriptionally upregulating BNIP3 to promote mitophagy and inhibit chondrocyte ferroptosis Open
This study underscores the role of Sesn2 as a novel protein that maintains chondrocyte metabolic homeostasis and redox balance, and demonstrates that MK8722, which activates Sesn2, may serve as a promising therapeutic approach for OA.
View article: Hydrogel-Based Microspheres for Intra-Articular Osteoarthritis Therapy: Multifunctional Carriers for Drug Delivery and Cartilage Repair: A Comprehensive Review
Hydrogel-Based Microspheres for Intra-Articular Osteoarthritis Therapy: Multifunctional Carriers for Drug Delivery and Cartilage Repair: A Comprehensive Review Open
Intra-articular therapy has long been a key focus in the treatment of osteoarthritis (OA), with both intra-articular drug injection and cell therapy offering significant advantages over systemic administration due to their superior local t…
View article: The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy
The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy Open
SO adversely affects short-term weight loss outcomes after LSG. However, the effect of SO on postoperative recurrent weight gain was not statistically significant, indicating that further research is needed. Furthermore, diabetes is an ind…
View article: Design and performance analysis of a slotted blade impeller for electrical submersible pumps
Design and performance analysis of a slotted blade impeller for electrical submersible pumps Open
View article: Dive3D: Diverse Distillation-based Text-to-3D Generation via Score Implicit Matching
Dive3D: Diverse Distillation-based Text-to-3D Generation via Score Implicit Matching Open
Distilling pre-trained 2D diffusion models into 3D assets has driven remarkable advances in text-to-3D synthesis. However, existing methods typically rely on Score Distillation Sampling (SDS) loss, which involves asymmetric KL divergence--…
View article: Tailor-made 3D printing TPU/PLA composites for damping and energy absorption
Tailor-made 3D printing TPU/PLA composites for damping and energy absorption Open
Commercially available thermoplastic polyurethane (TPU) materials for 3D printing often exhibit inadequate damping properties, limiting their application in damping scenarios. However, 3D printing TPU filaments specifically engineered for …
View article: The impact of metabolic syndrome on hepatocellular carcinoma: a mendelian randomization study
The impact of metabolic syndrome on hepatocellular carcinoma: a mendelian randomization study Open
View article: Research trends and major developments in 3D vision in 2024
Research trends and major developments in 3D vision in 2024 Open
View article: A Novel Fault Diagnosis Method for Electric Submersible Progressing Cavity Pumps: Addressing Imbalanced Mixed-Domain Datasets
A Novel Fault Diagnosis Method for Electric Submersible Progressing Cavity Pumps: Addressing Imbalanced Mixed-Domain Datasets Open
View article: GeoSplatting: Towards Geometry Guided Gaussian Splatting for Physically-based Inverse Rendering
GeoSplatting: Towards Geometry Guided Gaussian Splatting for Physically-based Inverse Rendering Open
Recent 3D Gaussian Splatting (3DGS) representations have demonstrated remarkable performance in novel view synthesis; further, material-lighting disentanglement on 3DGS warrants relighting capabilities and its adaptability to broader appli…
View article: Thermal Responsive Polyurethane/Brominated Isobutylene Isoprene Rubber Co-Continuous Ipns Elastomer: From Tunable Shape Memory Behavior to High Damping Properties
Thermal Responsive Polyurethane/Brominated Isobutylene Isoprene Rubber Co-Continuous Ipns Elastomer: From Tunable Shape Memory Behavior to High Damping Properties Open
View article: Corrosion Behavior of Pre-Oxidized Gh4169 Alloy with Solid Nacl Deposited in a Wet Oxygen Flow at 600 °C
Corrosion Behavior of Pre-Oxidized Gh4169 Alloy with Solid Nacl Deposited in a Wet Oxygen Flow at 600 °C Open
View article: Emulsions synergistic-stabilized by a hydroxyl sulfobetaine surfactant and SiO<sub>2</sub> nanoparticles and their potential application for enhanced oil recovery
Emulsions synergistic-stabilized by a hydroxyl sulfobetaine surfactant and SiO<sub>2</sub> nanoparticles and their potential application for enhanced oil recovery Open
The emulsion synergistic-stabilized by LHSB and SiO 2 nanoparticles through electrostatic repulsion has excellent stability under high temperature and salinity conditions.
View article: Relightable Neural Human Assets from Multi-view Gradient Illuminations
Relightable Neural Human Assets from Multi-view Gradient Illuminations Open
Human modeling and relighting are two fundamental problems in computer vision and graphics, where high-quality datasets can largely facilitate related research. However, most existing human datasets only provide multi-view human images cap…
View article: HumanGen: Generating Human Radiance Fields with Explicit Priors
HumanGen: Generating Human Radiance Fields with Explicit Priors Open
Recent years have witnessed the tremendous progress of 3D GANs for generating view-consistent radiance fields with photo-realism. Yet, high-quality generation of human radiance fields remains challenging, partially due to the limited human…
View article: High Multi-Environmental Mechanical Stability and Adhesive Transparent Ionic Conductive Hydrogels Used as Smart Wearable Devices
High Multi-Environmental Mechanical Stability and Adhesive Transparent Ionic Conductive Hydrogels Used as Smart Wearable Devices Open
Ionic conductive hydrogels used as flexible wearable sensor devices have attracted considerable attention because of their easy preparation, biocompatibility, and macro/micro mechanosensitive properties. However, developing an integrated c…
View article: Nerve-spring technique could achieve a functional trifecta outcome of robotic intracorporeal studer’s orthotopic neobladder in the male
Nerve-spring technique could achieve a functional trifecta outcome of robotic intracorporeal studer’s orthotopic neobladder in the male Open
Objectives: To summarize some key steps of functional improvement in robotic intracorporeal studer’s orthotopic neobladder (RISON) of males, especially for nerve-spring technique. We also presented the result of 1-year follow-up aime…
View article: The m7G-Related Long Noncoding RNA Signature Predicts Prognosis and Indicates Tumour Immune Infiltration in Colon Cancer
The m7G-Related Long Noncoding RNA Signature Predicts Prognosis and Indicates Tumour Immune Infiltration in Colon Cancer Open
With high morbidity and mortality, colon cancer (CC) is considered as one of the most often diagnosed cancers around the world. M7G-related lncRNA may provide a regulatory function in the formation of CC, but the principle of regulation is…
View article: Removal of Per- and Polyfluoroalkyl Substances by Electron Beam and Plasma Irradiation: A Mini-Review
Removal of Per- and Polyfluoroalkyl Substances by Electron Beam and Plasma Irradiation: A Mini-Review Open
The global prevalence and environmental risks of per- and polyfluoroalkyl substances (PFASs) have caused increasing concern regarding their strategic elimination from aqueous environments. It has recently been recognized that advanced oxid…
View article: Comprehensive Analysis of Necroptosis-Related Long Noncoding RNA Immune Infiltration and Prediction of Prognosis in Patients With Colon Cancer
Comprehensive Analysis of Necroptosis-Related Long Noncoding RNA Immune Infiltration and Prediction of Prognosis in Patients With Colon Cancer Open
Colon cancer (CC) is one of the most frequent malignancies in the world, with a high rate of morbidity and death. In CC, necroptosis and long noncoding RNA (lncRNAs) are crucial, but the mechanism is not completely clear. The goal of this …
View article: Comprehensive Analysis of Immune Implications and Prognostic Value of SPI1 in Gastric Cancer
Comprehensive Analysis of Immune Implications and Prognostic Value of SPI1 in Gastric Cancer Open
Background The transcription factor Spi-1 proto-oncogene (SPI1, also known as PU.1) is a key regulator of signal communication in the immune system and is essential for the development of myeloid cells and lymphocytes. However, the potenti…
View article: Identification of Circular RNA-Based Immunomodulatory Networks in Colorectal Cancer
Identification of Circular RNA-Based Immunomodulatory Networks in Colorectal Cancer Open
Background Circular RNAs (circRNAs) have been recently proposed as hub molecules in various diseases, especially in tumours. We found that circRNAs derived from ribonuclease P RNA component H1 (RPPH1) were highly expressed in colorectal ca…
View article: Comprehensive Analysis of Pyroptosis-Related Long Noncoding RNA Immune Infiltration and Prediction of Prognosis in Patients with Colon Cancer
Comprehensive Analysis of Pyroptosis-Related Long Noncoding RNA Immune Infiltration and Prediction of Prognosis in Patients with Colon Cancer Open
Colon cancer (CC) is one of the most prevalent malignant tumours of the alimentary canal. It is unclear whether pyroptosis-related lncRNA expression is correlated with CC prognosis. We discovered 20 pyroptosis-related lncRNAs that were exp…
View article: <i>RNF114</i> Silencing Inhibits the Proliferation and Metastasis of Gastric Cancer
<i>RNF114</i> Silencing Inhibits the Proliferation and Metastasis of Gastric Cancer Open
RNF114 (E3 ubiquitin ligase RING finger protein 114) was first identified as a zinc-binding protein that promotes psoriasis development; however, its role in gastric cancer is still unclear. We explored the relationship between RNF114
View article: Comprehensive Analysis and Prognosis Prediction of N6-methyladenosine-related Lncrnas in Immune Microenvironment Infiltration of Gastric Cancer
Comprehensive Analysis and Prognosis Prediction of N6-methyladenosine-related Lncrnas in Immune Microenvironment Infiltration of Gastric Cancer Open
BackgroundN6-methyladenosine (m6A) RNA modification plays an important role in regulating tumor microenvironment (TME) infiltration. However, the relationship between the expression pattern of m6A-related long non-coding RNAs (lncRNAs) and…
View article: The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2 Open
Worldwide, the incidence rate of gastric cancer ranks fifth, and the mortality rate of gastric cancer ranks third among all malignant tumors. However, the pathogenesis of gastric cancer remains poorly understood. In this study, we demonstr…
View article: Effect of Aging Time on the Microstructural Characterization and Corrosion Resistance of Al-4.5Cu-1Li-0.4Mg-0.4Ag-0.4Mn-0.5Zn Alloys
Effect of Aging Time on the Microstructural Characterization and Corrosion Resistance of Al-4.5Cu-1Li-0.4Mg-0.4Ag-0.4Mn-0.5Zn Alloys Open
Alloying based on Al-Li alloys plays an important factor for an adjustment of microstructure as well as corrosion behavior. In this study, we mainly focus on microstructural evolution of Al-4.5Cu-1Li-0.4Mg-0.4Ag-0.4Mn-0.5Zn alloy during ho…
View article: Identification of a Tumor Microenvironment‐Related Gene Signature Indicative of Disease Prognosis and Treatment Response in Colon Cancer
Identification of a Tumor Microenvironment‐Related Gene Signature Indicative of Disease Prognosis and Treatment Response in Colon Cancer Open
Background . The tumor microenvironment (TME) is associated with disease outcomes and treatment response in colon cancer. Here, we constructed a TME‐related gene signature that is prognosis of disease survival and may predict response to i…
View article: Microstructure of Al-5Cu-1Li-0.6Mg-0.5Ag-0.5Mn Alloys
Microstructure of Al-5Cu-1Li-0.6Mg-0.5Ag-0.5Mn Alloys Open
Microstructural optimization of Al-Li alloys plays a key role in the adjustment of mechanical properties as well as corrosion behavior. In this work, Al-5Cu-1Li-0.6Mg-0.5Ag-0.5Mn alloy was homogenized at different temperatures and holding …
View article: Area-Aware Routing and Spectrum Allocation for the Tidal Traffic Pattern in Metro Optical Networks
Area-Aware Routing and Spectrum Allocation for the Tidal Traffic Pattern in Metro Optical Networks Open
With the increasing bandwidth requirements for people and the development of urbanization, the movement of the population in the city (especially the supercity) has an increasing influence on the traffic distribution in both space and time…