W. Kŕause
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View article: Current treatment of HIV and prospects for cure
Current treatment of HIV and prospects for cure Open
HIV/AIDS has changed from a deadly disease in the early 1990s to a chronic treatment following huge research efforts. HIV had a great impact due to the long period until its fatal consequences in the form of AIDS appeared. As a consequence…
View article: The Covid-19 Recession in Germany: A Macro-Epidemiological Analysis
The Covid-19 Recession in Germany: A Macro-Epidemiological Analysis Open
What is the contribution of containment policies to output fluctuations in Germany during the COVID-19 pandemic? We extend a macro-epidemiological model based on the evidence that efficiency and labor wedges are the key distortions in the …
View article: Multiverse/Hyperverse Models: (4 + 1)-Dimensional Landscape (Black Saturns, Bousso-Hawking Nucleation, Gogberashvili Multiverses, Schwarzschild-De Sitter Nurseries) and a (3 + 1)-Dimensional Model for Dark Energy
Multiverse/Hyperverse Models: (4 + 1)-Dimensional Landscape (Black Saturns, Bousso-Hawking Nucleation, Gogberashvili Multiverses, Schwarzschild-De Sitter Nurseries) and a (3 + 1)-Dimensional Model for Dark Energy Open
International audience
View article: mRNA—From COVID-19 Treatment to Cancer Immunotherapy
mRNA—From COVID-19 Treatment to Cancer Immunotherapy Open
This review provides an overview covering mRNA from its use in the COVID-19 pandemic to cancer immunotherapy, starting from the selection of appropriate antigens, tumor-associated and tumor-specific antigens, neoantigens, the basics of opt…
View article: Multiverse Model: External Universe(s) as Source of Dark Energy
Multiverse Model: External Universe(s) as Source of Dark Energy Open
The Lambda Cold Dark Matter (ΛCDM) model is currently the best model to describe the development of the Universe from the Big Bang to the present time. It is composed of six parameters, two of them, Dark Energy (DE) and CDM, with unknown p…
View article: Resistance to anti-tubulin agents: From vinca alkaloids to epothilones
Resistance to anti-tubulin agents: From vinca alkaloids to epothilones Open
This review describes the mechanism of action - inhibition of microtubules - and the most important mechanisms of resistance for vinca alkaloids, taxanes and epothilones. Resistance is a major problem in vinca and taxane chemotherapy and a…