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View article: Iterative and data-driven development of a digital measure of motivation, impulsivity, and risk-taking (Preprint)
Iterative and data-driven development of a digital measure of motivation, impulsivity, and risk-taking (Preprint) Open
BACKGROUND Basal ganglia (BG) dysfunction is the hallmark of several neurological and neuropsychiatric disorders. BG dysfunction impairs cost-benefit decision-making, a brain computational process of trading off between reward and costs, …
View article: Exploratory Sensor-based Outcome Measures Show Divergent Slopes of Motor Sign Progression in Parkinson’s Disease Patients Treated with Prasinezumab
Exploratory Sensor-based Outcome Measures Show Divergent Slopes of Motor Sign Progression in Parkinson’s Disease Patients Treated with Prasinezumab Open
Digital health technology (DHT) tools for Parkinson’s disease (PD) such as smartphones and wearable sensors enable remote and frequent measurement of motor signs which may facilitate research on novel treatments for PD. Here, we report the…
View article: Accelerated Muscle Deoxygenation in Aerobically Fit Subjects During Exhaustive Exercise Is Associated With the ACE Insertion Allele
Accelerated Muscle Deoxygenation in Aerobically Fit Subjects During Exhaustive Exercise Is Associated With the ACE Insertion Allele Open
Introduction The insertion/deletion (I/D) polymorphism in the gene for the major regulator of vascular tone, angiotensin-converting enzyme-insertion/deletion (ACE-I/D) affects muscle capillarization and mitochondrial biogenesis with endura…
View article: Remote monitoring of progression in early Parkinson’s disease: reliability and validity of the Roche PD Mobile Application v2
Remote monitoring of progression in early Parkinson’s disease: reliability and validity of the Roche PD Mobile Application v2 Open
Digital health technologies (DHTs) enable remote and therefore frequent measurement of motor signs, potentially providing reliable and valid estimates of motor sign severity and progression in Parkinson’s disease (PD). The Roche PD Mobile …
View article: Age-Dependent Asymmetry of Wrist Position Sense Is Not Influenced by Stochastic Tactile Stimulation
Age-Dependent Asymmetry of Wrist Position Sense Is Not Influenced by Stochastic Tactile Stimulation Open
Stochastic stimulation has been shown to improve movement, balance, the sense of touch, and may also improve position sense. This stimulation can be non-invasive and may be a simple technology to enhance proprioception. In this study, we i…
View article: Wearable Sensors in Ambulatory Individuals With a Spinal Cord Injury: From Energy Expenditure Estimation to Activity Recommendations
Wearable Sensors in Ambulatory Individuals With a Spinal Cord Injury: From Energy Expenditure Estimation to Activity Recommendations Open
Inappropriate physical inactivity is a global health problem increasing the risk of cardiometabolic diseases. Wearable sensors show great potential to promote physical activity and thus a healthier lifestyle. While commercial activity trac…
View article: Does electrical stimulation in the lower urinary tract increase urine production? A randomised comparative proof-of-concept study in healthy volunteers
Does electrical stimulation in the lower urinary tract increase urine production? A randomised comparative proof-of-concept study in healthy volunteers Open
Urine production is increased during electrical stimulation with a bigger impact of higher frequencies. This might be relevant for methodological aspects in the assessment of lower urinary tract afferent function and for patients with impa…
View article: Concentric and Eccentric Pedaling-Type Interval Exercise on a Soft Robot for Stable Coronary Artery Disease Patients: Toward a Personalized Protocol
Concentric and Eccentric Pedaling-Type Interval Exercise on a Soft Robot for Stable Coronary Artery Disease Patients: Toward a Personalized Protocol Open
ClinicalTrials.gov NCT02845063; https://clinicaltrials.gov/ct2/show/NCT02845063.
View article: Concentric and eccentric pedaling-type interval exercise on a soft robot for stable coronary artery disease patients: Toward a personalized protocol
Concentric and eccentric pedaling-type interval exercise on a soft robot for stable coronary artery disease patients: Toward a personalized protocol Open
Background: Cardiovascular diseases are the leading causes of death worldwide, and coronary artery disease (CAD) is one of the most common causes of death in Europe. Leading cardiac societies recommend exercise as an integral part of cardi…
View article: Reliability of Wearable-Sensor-Derived Measures of Physical Activity in Wheelchair-Dependent Spinal Cord Injured Patients
Reliability of Wearable-Sensor-Derived Measures of Physical Activity in Wheelchair-Dependent Spinal Cord Injured Patients Open
Physical activity (PA) has been shown to have a positive influence on functional recovery in patients after a spinal cord injury (SCI). Hence, it can act as a confounder in clinical intervention studies. Wearable sensors are used to quanti…
View article: Estimation of Energy Expenditure in Wheelchair-Bound Spinal Cord Injured Individuals Using Inertial Measurement Units
Estimation of Energy Expenditure in Wheelchair-Bound Spinal Cord Injured Individuals Using Inertial Measurement Units Open
A healthy lifestyle reduces the risk of cardio-vascular disease. As wheelchair-bound individuals with spinal cord injury (SCI) are challenged in their activities, promoting and coaching an active lifestyle is especially relevant. Although …
View article: Concentric and Eccentric Pedaling-Type Interval Exercise on a Soft Robot for Stable Coronary Artery Disease Patients: Toward a Personalized Protocol (Preprint)
Concentric and Eccentric Pedaling-Type Interval Exercise on a Soft Robot for Stable Coronary Artery Disease Patients: Toward a Personalized Protocol (Preprint) Open
BACKGROUND Cardiovascular diseases are the leading causes of death worldwide, and coronary artery disease (CAD) is one of the most common causes of death in Europe. Leading cardiac societies recommend exercise as an integral part of cardi…
View article: MP09-07 DOES ELECTRICAL STIMULATION IN THE LOWER URINARY TRACT INDUCE DIURESIS?
MP09-07 DOES ELECTRICAL STIMULATION IN THE LOWER URINARY TRACT INDUCE DIURESIS? Open
You have accessJournal of UrologyBladder & Urethra: Anatomy, Physiology & Pharmacology I1 Apr 2018MP09-07 DOES ELECTRICAL STIMULATION IN THE LOWER URINARY TRACT INDUCE DIURESIS? Stéphanie van der Lely, Martina D. Liechti, Werner L. Popp, T…
View article: Method for Improving Psychophysical Threshold Estimates by Detecting Sustained Inattention
Method for Improving Psychophysical Threshold Estimates by Detecting Sustained Inattention Open
Psychophysical procedures are applied in various fields to assess sensory thresholds. During experiments, sampled psychometric functions are usually assumed to be stationary. However, perception can be altered, for example by loss of atten…
View article: Monitoring Upper Limb Recovery after Cervical Spinal Cord Injury: Insights beyond Assessment Scores
Monitoring Upper Limb Recovery after Cervical Spinal Cord Injury: Insights beyond Assessment Scores Open
Tracking day-to-day UL activity is necessary to gain insights into the real impact of a patient's impairments on their UL movements during therapy and during their leisure time. In the future, this novel methodology may be used to reliably…
View article: Reliable and Rapid Robotic Assessment of Wrist Proprioception Using a Gauge Position Matching Paradigm
Reliable and Rapid Robotic Assessment of Wrist Proprioception Using a Gauge Position Matching Paradigm Open
Quantitative assessments of position sense are essential for the investigation of proprioception, as well as for diagnosis, prognosis and treatment planning for patients with somatosensory deficits. Despite the development and use of vario…
View article: Design and Evaluation of a Fiber-Optic Grip Force Sensor with Compliant 3D-Printable Structure for (f)MRI Applications
Design and Evaluation of a Fiber-Optic Grip Force Sensor with Compliant 3D-Printable Structure for (f)MRI Applications Open
Grip force sensors compatible with magnetic resonance imaging (MRI) are used in human motor control and decision-making research, providing objective and sensitive behavioral outcome measures. Commercial sensors are expensive, cover limite…