Widya N. Insani
YOU?
Author Swipe
View article: Comparative Effectiveness of Mycophenolate Mofetil and Tacrolimus as a Second-Line Therapy for Autoimmune Hepatitis: A Systematic Review and Meta-Analysis
Comparative Effectiveness of Mycophenolate Mofetil and Tacrolimus as a Second-Line Therapy for Autoimmune Hepatitis: A Systematic Review and Meta-Analysis Open
Objective: Autoimmune hepatitis (AIH) is a chronic immune-mediated liver disease that usually responds to corticosteroids ± azathioprine (AZA). However, some patients are intolerant or refractory to first-line therapy and require second-li…
View article: Unintended Medication Discrepancies (UMD) Pada Saat Rekonsiliasi Transfer dalam Konteks Negara Berpenghasilan Rendah dan Menengah : Tinjauan Naratif
Unintended Medication Discrepancies (UMD) Pada Saat Rekonsiliasi Transfer dalam Konteks Negara Berpenghasilan Rendah dan Menengah : Tinjauan Naratif Open
Unintended medication discrepancies (UMD) sering terjadi selama transisi perawatan, terutama di negara berpenghasilan rendah dan menengah (LMICs), yang masih memiliki berbagai keterbatasan sistem seperti ketiadaan protokol standar, sistem …
View article: Pharmacist-Led Digital Health Interventions to Improve Treatment Outcomes in Patients with Hypertension - A Systematic Review
Pharmacist-Led Digital Health Interventions to Improve Treatment Outcomes in Patients with Hypertension - A Systematic Review Open
With the advancement of digital technologies, pharmacist-led digital health interventions (DHI) have emerged as a promising strategy to improve hypertension management. This systematic review evaluated randomized controlled trials (RCTs) p…
View article: Factors Influencing Medication Non-Adherence in Patients with Chronic Diseases and Disabilities: Insights from a National Survey in Indonesia
Factors Influencing Medication Non-Adherence in Patients with Chronic Diseases and Disabilities: Insights from a National Survey in Indonesia Open
More than half of the patients (66.3%) with chronic diseases and disabilities were non-adherent to their medication. Therefore, interventions designed to improve medication adherence in this population should consider specific patient-rela…
View article: Digital Health Technology Interventions for Improving Medication Safety: Systematic Review of Economic Evaluations
Digital Health Technology Interventions for Improving Medication Safety: Systematic Review of Economic Evaluations Open
Background Medication-related harm, including adverse drug events (ADEs) and medication errors, represents a significant iatrogenic burden in clinical care. Digital health technology (DHT) interventions can significantly enhance medication…
View article: Clinical Presentations and Characteristics of NSAIDs Hypersensitivity in a Tertiary Care Hospital in Indonesia: A Case Series
Clinical Presentations and Characteristics of NSAIDs Hypersensitivity in a Tertiary Care Hospital in Indonesia: A Case Series Open
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely administered in all age groups due to their effectiveness in reducing fever, relieving pain, and reducing inflammation. However, they have also been identified as the second most co…
View article: Pharmacist-Led Digital Health Interventions for Patients with Diabetes: A Systematic Review
Pharmacist-Led Digital Health Interventions for Patients with Diabetes: A Systematic Review Open
Digital health interventions have emerged as a promising approach for patient care. The aim of this study was to conduct a systematic review of pharmacist-led digital health interventions for patients with diabetes. The PubMed database was…
View article: Interventions to improve pharmacists’ competency in chronic disease management: a systematic review of randomized controlled trials
Interventions to improve pharmacists’ competency in chronic disease management: a systematic review of randomized controlled trials Open
Introduction Effective chronic disease management (CDM) is vital for addressing chronic disease challenges. Given the importance of ensuring pharmacists’ competence in CDM, interventions targeting knowledge, skills, and attitudes are essen…
View article: Exploring the association of adverse drug reactions with medication adherence and quality of life among hypertensive patients: a cross-sectional study
Exploring the association of adverse drug reactions with medication adherence and quality of life among hypertensive patients: a cross-sectional study Open
View article: Prevalence of cardiovascular drug-related adverse drug reactions consultations in UK primary care: A cross-sectional study
Prevalence of cardiovascular drug-related adverse drug reactions consultations in UK primary care: A cross-sectional study Open
Background Adverse drug reactions (ADRs) represent a significant barrier to achieve optimal treatment outcomes. Cardiovascular drugs, including antihypertensive drugs, lipid-lowering drugs, and antithrombotic drugs, are among the most pres…
View article: Impact of ACEIs and ARBs-related adverse drug reaction on patients’ clinical outcomes: a cohort study in UK primary care
Impact of ACEIs and ARBs-related adverse drug reaction on patients’ clinical outcomes: a cohort study in UK primary care Open
Background Adverse drug reaction (ADR) related to angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) may negatively affect patients’ treatment outcomes. Aim To investigate the impact of ACEIs/ARBs-rel…
View article: Statin‐related adverse drug reactions in UK primary care consultations: A retrospective cohort study to evaluate the risk of cardiovascular events and all‐cause mortality
Statin‐related adverse drug reactions in UK primary care consultations: A retrospective cohort study to evaluate the risk of cardiovascular events and all‐cause mortality Open
Aims To investigate the risk of cardiovascular disease (CVD) events and all‐cause mortality in patients with statin‐related adverse drug reaction (ADR) consultation in primary care and examine whether different treatments following the ADR…
View article: Genetic variation of ABCB1 (rs1128503, rs1045642) and CYP2E1 rs3813867 with the duration of tuberculosis therapy: a pilot study among tuberculosis patients in Indonesia
Genetic variation of ABCB1 (rs1128503, rs1045642) and CYP2E1 rs3813867 with the duration of tuberculosis therapy: a pilot study among tuberculosis patients in Indonesia Open
Objective The risk of contracting tuberculosis (TB) and the efficacy of TB therapy are affected by several factors, including genetic variation among populations. In the Indonesian population, data on the genes involved in drug transport a…
View article: Effectiveness and Safety Profile of Alternative Tobacco and Nicotine Products for Smoking Reduction and Cessation: A Systematic Review
Effectiveness and Safety Profile of Alternative Tobacco and Nicotine Products for Smoking Reduction and Cessation: A Systematic Review Open
CRD42020205830.
View article: Prevalence of adverse drug reactions in the primary care setting: A systematic review and meta-analysis
Prevalence of adverse drug reactions in the primary care setting: A systematic review and meta-analysis Open
Background Adverse drug reactions (ADRs) represent a major cause of iatrogenic morbidity and mortality in patient care. While a substantial body of work has been undertaken to characterise ADRs in the hospital setting, the overall burden o…
View article: Lack of Awareness of the Impact of Improperly Disposed Of Medications and Associated Factors: A Cross-Sectional Survey in Indonesian Households
Lack of Awareness of the Impact of Improperly Disposed Of Medications and Associated Factors: A Cross-Sectional Survey in Indonesian Households Open
Introduction: Disposal of unused medications through environmentally unsafe routes is common in Indonesia. The lack of awareness of the impact of improperly disposed of medications is a significant contributing factor. The objectives of th…
View article: Pneumococcal Vaccination for Children in Asian Countries: A Systematic Review of Economic Evaluation Studies
Pneumococcal Vaccination for Children in Asian Countries: A Systematic Review of Economic Evaluation Studies Open
Background: Evidence on costs and health benefits of pneumococcal conjugate vaccine (PCV) for children in Asian countries is limited but growing. As a region with a considerably high burden of pneumococcal disease, it is prominent to have …
View article: Improper disposal practice of unused and expired pharmaceutical products in Indonesian households
Improper disposal practice of unused and expired pharmaceutical products in Indonesian households Open
Disposal of unwanted pharmaceutical products through environmentally unsafe route was prevalent among the respondents. There is also a lack of awareness of the impact of improperly disposed of medicines for the ecosystem. These findings ca…
View article: Assessment of Health-Related Quality of Life among Tuberculosis Patients in a Public Primary Care Facility in Indonesia
Assessment of Health-Related Quality of Life among Tuberculosis Patients in a Public Primary Care Facility in Indonesia Open
Background and Objectives: Evaluation of health-related quality of life (HRQoL) among tuberculosis (TB) patients could improve understanding about the burden associated with the diseases. There is a paucity of research regarding evaluation…
View article: <p>Pattern of medication use in geriatric patients at primary healthcare facilities in Karawang, Indonesia</p>
Pattern of medication use in geriatric patients at primary healthcare facilities in Karawang, Indonesia Open
Our findings highlight that polypharmacy and prescription of essential drugs remain subjects of concern in geriatric health care. Regular medication review and promoting the use of the essential drug list among health care professionals ar…
View article: Polypharmacy leads to increased prevalence of potentially inappropriate medication in the Indonesian geriatric population visiting primary care facilities
Polypharmacy leads to increased prevalence of potentially inappropriate medication in the Indonesian geriatric population visiting primary care facilities Open
PIM is a concern in the Indonesian geriatric population. Health care professionals are encouraged to review the medications of their geriatric patients using updated safety guidelines to prevent risks associated with PIM.
View article: Characteristics of drugs safety signals that predict safety related product information update
Characteristics of drugs safety signals that predict safety related product information update Open
Purpose Investigation of drug safety signals is one of the major tasks in pharmacovigilance. Among many potential signals identified, only a few reflect adverse drug reactions requiring regulatory actions, such as product information (PI) …
View article: Identification of Dysbiosis Related Bacteria from New Zealand’s White Rabbit Intestinal Treated With Lactobacillus plantarum IS-10506 as Probiotics Food Supplementation
Identification of Dysbiosis Related Bacteria from New Zealand’s White Rabbit Intestinal Treated With Lactobacillus plantarum IS-10506 as Probiotics Food Supplementation Open
The gastrointestinal microoganisms encompass thousands of bacterial species that constitute a relatively stable ecosystem inside human body. Dysbiosis is an imbalance condition of beneficiary microbacteria cause by newer microorganism. Thi…
View article: Recent Strategies and Patients Preferences of Community Pharmacists Asthma Service
Recent Strategies and Patients Preferences of Community Pharmacists Asthma Service Open
Asthma control depends on the accessibility of effective medicines and its appropriate use. Given that many issues in the asthma management are related to inappropriate use of medication, community pharmacists are in the excellent position…
View article: Methods of defining the non-inferiority margin in randomized, double-blind controlled trials: a systematic review
Methods of defining the non-inferiority margin in randomized, double-blind controlled trials: a systematic review Open