William S. Ball
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View article: A targeted cell lysis mechanism facilitates toxin release in Clostridioides difficile
A targeted cell lysis mechanism facilitates toxin release in Clostridioides difficile Open
Clostridioides difficile infection is associated with the production of two large toxins, TcdA and TcdB. The toxins are encoded in a pathogenicity locus along with a phage-like holin protein, TcdE, the remnants of a phage endolysin, TcdL, …
View article: 1113 Evaluating the Referral Pathway for Colonoscopy in a District General Hospital
1113 Evaluating the Referral Pathway for Colonoscopy in a District General Hospital Open
Objectives We aim to evaluate: Method, urgency and appropriateness of colonoscopy referrals. Colonoscopies repeated within two years. Reasoning behind procedure modification or cancellation on the day Method Data was collected between 5/1/…
View article: 470 Colorectal Cancer Mortality Rates in UK Shropshire County
470 Colorectal Cancer Mortality Rates in UK Shropshire County Open
Aim Evaluate outcomes of patients dying within 12 months from diagnosis of colorectal cancer in Shropshire County. Method Single-centre retrospective review of patients who died within 12 months of diagnosis between 2020-2024.Each patient’…
View article: DIVERT-Ca: unveiling the hidden link between acute diverticulitis and colorectal cancer risk—multicentre retrospective study
DIVERT-Ca: unveiling the hidden link between acute diverticulitis and colorectal cancer risk—multicentre retrospective study Open
Introduction Colorectal cancer (CRC) is the third most common cancer worldwide, accounting for approximately 10% of all malignancies. Emerging trends of association with risk factors such as diverticulitis highlight the need for updated sc…
View article: 1289 Rare Case of a Patient with Simultaneous Incarcerated Epigastric Hernia and De Garengeot Hernia: A Case Report
1289 Rare Case of a Patient with Simultaneous Incarcerated Epigastric Hernia and De Garengeot Hernia: A Case Report Open
Case Presentation 66-year-old lady presents to surgical unit with main complaint of epigastric pain and swelling. She noticed lump in both groins. She had no previous abdominal surgery and has no past medical history. Examination and blood…
View article: Modeling Stratospheric Polar Vortex Variation and Identifying Vortex Extremes Using Explainable Machine Learning
Modeling Stratospheric Polar Vortex Variation and Identifying Vortex Extremes Using Explainable Machine Learning Open
The winter stratospheric polar vortex (SPV) exhibits considerable variability in magnitude and structure, which can result in extreme SPV events. These extremes can subsequently influence weather in the troposphere from weeks to months and…
View article: Comment on egusphere-2022-701
Comment on egusphere-2022-701 Open
Abstract. There is evidence that the ozone layer has begun to recover owing to the ban on the production of halogen-containing ozone-depleting substances (hODS) accomplished by the Montreal Protocol and its Amendments (MPA). However, recen…
View article: The clinically extremely vulnerable to COVID: Identification and changes in healthcare while self-isolating (shielding) during the coronavirus pandemic.
The clinically extremely vulnerable to COVID: Identification and changes in healthcare while self-isolating (shielding) during the coronavirus pandemic. Open
ObjectiveIn March 2020, Scottish government identified people clinically extremely vulnerable to COVID due to pre-existing health conditions. These people were advised to strictly self-isolate (shield) at home. We examined who was identifi…
View article: “All about communication" - a perspective on our public involvement practices in the Networked Data Lab in Grampian.
“All about communication" - a perspective on our public involvement practices in the Networked Data Lab in Grampian. Open
ObjectivesThe Networked Data Lab (NDL) in Grampian has been embedding evidence-informed practices of working in active partnership with the public in producing insights on population health care. We aim to describe and explain our experien…