William Beardall
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View article: Absorb & Escape: Overcoming Single Model Limitations in Generating Genomic Sequences
Absorb & Escape: Overcoming Single Model Limitations in Generating Genomic Sequences Open
Recent advances in immunology and synthetic biology have accelerated the development of deep generative methods for DNA sequence design. Two dominant approaches in this field are AutoRegressive (AR) models and Diffusion Models (DMs). Howev…
View article: Predicting cell type-specific epigenomic profiles accounting for distal genetic effects
Predicting cell type-specific epigenomic profiles accounting for distal genetic effects Open
Understanding genetic variants effects on the epigenome is crucial for interpreting genome-wide association studies (GWAS) results, yet profiling these effects across the non-coding genome remains challenging due to the scalability limits …