Explanipedia

Response to Commentary on “Prevalence of Local IgE Elevation and Its Effect on Intranasal Capsaicin Therapy in the Nonallergic Rhinitis Population” Open

Kunal Shetty, Salman Hasan, Christopher Bankston, Dylan G. Vance, Elaijah Islam , et al. · 2025

Prevalence of Local IgE Elevation and Its Effect on Intranasal Capsaicin Therapy in the Nonallergic Rhinitis Population Open

Kunal Shetty, Salman Hasan, Christopher Bankston, Dylan G. Vance, Elaijah Islam , et al. · 2025

Three‐Year Outcomes After Temperature‐Controlled Radiofrequency Treatment of Nasal Airway Obstruction Open

William C. Yao, Randall A. Ow, Michael J. Sillers, Nathan E. Nachlas, Curtis D. Johnson , et al. · 2025

Objective To evaluate the long‐term safety and effectiveness of temperature‐controlled radiofrequency (TCRF) treatment of nasal valve collapse (NVC) in patients with nasal airway obstruction (NAO). Study Design This is an extended follow‐u…

Temperature‐controlled radiofrequency treatment of the nasal valve in nasal airway obstruction patients with septal deviation Open

Dennis M. Tang, Philip G. Chen, Arthur W. Wu, William C. Yao · 2024

Key points Nasal valve treatment with TCRF results in NAO symptom improvement in the presence of septal deviation. Severe septal deviation does not impact the beneficial effect of TCRF nasal valve treatment. Symptoms improve with TCRF nasa…

Semi-Automated Virtual Endoscopy of the Frontal Recess Open

Jafar Ali, William C. Yao, Martin J. Citardi · 2024

Introduction: Virtual endoscopy (VE) is the computer-based reprocessing of diagnostic imaging to simulate endoscopy of an anatomic region of interest. VE of the Frontal Sinus Outflow Tract (FSOT) may assist surgical planning and education.…

Two‐year outcomes of temperature‐controlled radiofrequency device treatment of the nasal valve for patients with nasal airway obstruction Open

William C. Yao, Jordan Pritikin, Michael J. Sillers, Henry P. Barham · 2023

Background The objective of this study was to evaluate long‐term symptom improvements in patients with nasal airway obstruction (NAO) secondary to nasal valve collapse (NVC) following minimally invasive temperature‐controlled radiofrequenc…

Dural sinus narrowing in patients with spontaneous anterior skull base cerebrospinal fluid leak Open

Karim Asi, Brian Cameron, Elliot R. Friedman, Jeffrey Paul Radabaugh, Martin J. Citardi , et al. · 2023

Objectives Current evidence suggests a link between idiopathic intracranial hypertension (IIH) and spontaneous cerebrospinal fluid (sCSF) leak, as well as between IIH and dural venous sinus (DVS) narrowing. However, there are limited data …

Neurofibroma of the internal carotid artery cavernous sympathetic plexus: illustrative case Open

Duncan J. Trimble, Bryden H. Dawes, Hussein A. Zeineddine, Katie B. Guttenberg, William C. Yao , et al. · 2023

BACKGROUND Intracranial carotid sympathetic plexus (CSP) nerve sheath tumors have rarely been reported in the literature. This study describes the first reported case of a CSP neurofibroma and the first case of a CSP nerve sheath tumor tre…

Determinants of physician assessment of chronic rhinosinusitis disease control using EPOS 2020 criteria and the importance of incorporating patient perspectives of disease control Open

Ahmad R. Sedaghat, David S. Caradonna, Rakesh K. Chandra, Christine B. Franzese, Stacey T. Gray , et al. · 2023

Background We identify chronic rhinosinusitis (CRS) manifestations associated with how rhinologists assess CRS control, with a focus on patient perspectives (patient‐reported CRS control). Methods Fifteen rhinologists were provided with re…

Antiplatelet and Anticoagulation Therapy and the Risk of Pituitary Apoplexy in Pituitary Adenoma Patients Open

Bronson Ciavarra, Timothy McIntyre, Matthew J. Kole, Wen Li, William C. Yao , et al. · 2023

Purpose Pituitary apoplexy can be a life threatening and vision compromising event. Antiplatelet and anticoagulation use has been reported as a contributing factor in pituitary apoplexy (PA). Utilizing one of the largest cohorts in the lit…

Three-Dimensional Printed Models to Accelerate Resident Surgical Learning Curve for Standard Endoscopic Sinus Surgery Techniques Open

Jumah G. Ahmad, Alexander J. Citardi, Amber Luong, William C. Yao · 2022

Background : Endoscopic sinus surgery presents significant visuospatial challenges to surgical trainees. We tested the utility of novel 3D printed models to simulate sinus surgery tasks to improve endoscopic skillsets in resident trainees.…

Hydraulic dissection technique during endoscopic sinus surgery using a novel balloon sinus dilation device Open

Isaac L. Schmale, William C. Yao, Martin J. Citardi · 2021

Background More than a decade after its introduction, some rhinologic surgeons have incorporated the technique of balloon sinus dilation (BSD) technology into “hybrid” endoscopic sinus surgery (ESS) procedures. A novel BSD device which can…

Revisiting the controversy: The role of fungi in chronic rhinosinusitis Open

Matthew A. Tyler, Kent Lam, Michael J. Marino, William C. Yao, Isaac L. Schmale , et al. · 2021

In the last two decades, the development of culture‐independent genomic techniques has facilitated an increased appreciation of the microbiota‐immunity interactions and their role in a multitude of chronic inflammatory diseases such as chr…

N95 respirator reuse, decontamination methods, and microbial burden: A randomized controlled trial Open

Zi Yang Jiang, Zhen Huang, Isaac L. Schmale, Eric L. Brown, Michael Lorenz , et al. · 2021

Characterizing the complexity of frontal endoscopic sinus surgery: a multi‐institutional, prospective, observational trial Open

Philip G. Chen, Joshua M. Levy, Garret Choby, Kristine A. Smith, William C. Yao , et al. · 2020

Full Remission of Long-Term Premenstrual Dysphoric Disorder-Like Symptoms Following Resection of a Pituitary Adenoma: Case Report Open

Guangrong Lu, Tiana M. Shiver, Spiros Blackburn, William C. Yao, Meenakshi B. Bhattacharjee , et al. · 2020

BACKGROUND Few case reports exist in the literature of patients with pituitary adenoma presenting with premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD). Complete remission of persistent PMDD symptoms after surgical rem…

Aerosol generation with common rhinologic devices: cadaveric study conducted in a surgical suite Open

Bailey LeConte, Garren M. I. Low, Martin J. Citardi, William C. Yao, Arturo Eguia , et al. · 2020

To the Editor: Adding to the understanding of aerosol generation of rhinologic instruments in recently published data, we evaluated additional instruments typically used for in-office procedures and analyzed generation of submicron-sized a…

Image-Guided Surgery and Intraoperative Imaging in Rhinology: Clinical Update and Current State of the Art Open

Isaac L. Schmale, Laura J. Vandelaar, Amber Luong, Martin J. Citardi, William C. Yao · 2020

Introduction: Image-guided surgery (IGS) has gained widespread acceptance in otorhinolaryngology for its applications in sinus and skull base surgery. Although the core concepts of IGS have not changed, advances in image guidance technolog…

Using Motion Sensors to Understand Collaborative Interactions in Digital Fabrication Labs Open

Edwin Chng, Mohamed Raouf Seyam, William C. Yao, Bertrand Schneider · 2020

Evaluating the endometabolic and bone health effects of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukaemia: a systematic review protocol Open

Janatani Balakumaran, Tanisha Birk, Breanne Golemiec, Wryan Helmeczi, Jeyanth Inkaran , et al. · 2019

Introduction Chronic Myeloid Leukaemia (CML) constitutes 15% of new adult leukaemia cases as well as 2%–3% of leukaemia in children under 15% and 9% of leukaemias in adolescents 15–19 years of age annually. The introduction of Tyrosine Kin…

Analysis of Sinonasal Microbiota in Exacerbations of Chronic Rhinosinusitis Subgroups Open

Laura J. Vandelaar, Blake Hanson, Michael J. Marino, William C. Yao, Amber Luong , et al. · 2019

Objective Microbiome analyses now allow precise determination of the sinus microbiota of patients with exacerbations of chronic rhinosinusitis (CRS). The aim of this report is to describe the sinus microbiota of acute exacerbations in CRS …

Author Index Open

Klaus Aktories, Mohammad Ali, Claudia Angelini, B Baglivo, Eli Bar , et al. · 2019

International assessment of inter‐ and intrarater reliability of the International Frontal Sinus Anatomy Classification system Open

Ricardo Villarreal, Bozena Wrobel, Luis Macias‐Valle, Greg E. Davis, Thomas J. Prihoda , et al. · 2018

Background Inconsistencies in the nomenclature of structures of the frontal sinus have impeded the development of a validated “reference standard” classification system that surgeons can reliably agree upon. The International Frontal Sinus…

A Case of Mistaken Inflammatory Pseudotumor Open

Steven K. Dennis, Kevin J Caceres, William C. Yao · 2018

Aim: Inflammatory myofibroblastic pseudotumor (IMT), part of the inflammatory pseudotumor (IPT) family, shares many presenting features with more common expansile sinonasal masses and is unlikely to be diagnosed without clinical suspicion.…

Cutting‐edge endonasal surgical approaches to thyroid ophthalmopathy Open

Matthew A. Tyler, Caroline C. Zhang, Alok T. Saini, William C. Yao · 2018

Objective Thyroid orbitopathy is a poorly understood extrathyroidal manifestation of Graves' disease that can cause disfiguring proptosis and vision loss. Orbital decompression surgery for Graves' orbitopathy (GO) can address both cosmetic…

Laser-generated shockwaves enhance antibacterial activity against biofilms<i>in vitro</i> Open

William C. Yao, Edward C. Kuan, Nathan C. Francis, Maie A. St. John, Warren S. Grundfest , et al. · 2017

LGS enhances the efficacy of topical antibiotics in an in vitro model. This has significant implications for clinical applications in the management of chronic soft tissue infections and recalcitrant chronic rhinosinusitis. Lasers Surg. Me…

Laser Generated Shockwave Therapy of Bacterial Biofilms: From Benchtop to Pre-Clinical Studies Open

William C. Yao · 2017

The presence of bacterial biofilms in wounds presents a major complication in wound treatments, significantly increasing morbidity and mortality. Biofilms delay wound healing, promote the growth of bacteria, and are a persistent source of …

Flexible Microsensor Technology for Real-Time Navigation Tracking in Balloon Sinus Ostial Dilation Open

Kent Lam, Jo‐Lawrence Bigcas, Amber Luong, William C. Yao, Martin J. Citardi · 2017

Background Microsensor navigation has the potential to aid balloon sinus ostial dilation by providing real-time tracking of balloon devices within the complex anatomy of the sinonasal cavities. Objective This feasibility study evaluated th…

Laser-Generated Shockwaves as a Treatment to Reduce Bacterial Load and Disrupt Biofilm Open

Nathan C. Francis, William C. Yao, Warren S. Grundfest, Zachary Taylor · 2016

LGS therapy is a new treatment for infected wounds, allowing rapid disruption of biofilm to 1) remove bacteria and 2) increase susceptibility of remaining biofilm to topical antibiotics. This can lead to improved wound healing times, reduc…

Nasal Mucosal Melanosis may act as a Harbinger of Melanoma: A Case Report Open

William C. Yao, Kevin S. Emerick, Stefan Kraft, Eric H. Holbrook · 2016

Background The progression from a benign pigmented lesion on the skin to cutaneous melanoma is better understood, and it could be presumed that a similar progression occurs with mucosal lesions. However, to our knowledge, there has never b…

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