William E. Trick
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View article: Epidemiology of Colon Cancer Screening in a Safety-Net Setting
Epidemiology of Colon Cancer Screening in a Safety-Net Setting Open
Maintaining a colon cancer registry was complex owing to the dynamic nature of screening status and unstable primary care attendance. Regional integration of electronic health records could substantially reduce manual effort.
View article: Incarceration is a key driver of racial disparities in community-associated methicillin-resistant Staphylococcus aureus infections in Cook County, IL
Incarceration is a key driver of racial disparities in community-associated methicillin-resistant Staphylococcus aureus infections in Cook County, IL Open
High risks of MRSA infection and colonization have consistently been documented among incarcerated and recently incarcerated individuals. Our results suggest that incarceration may also drive infections among non-incarcerated individuals l…
View article: Variations in Acceptance of American Society of Addiction Medicine (ASAM) Continuum Levels of Care for Substance Use Disorder Treatment in an Urban Safety Net Primary Care Health Setting: A Qualitative and Quantitative Analysis and Implications for Health Equity
Variations in Acceptance of American Society of Addiction Medicine (ASAM) Continuum Levels of Care for Substance Use Disorder Treatment in an Urban Safety Net Primary Care Health Setting: A Qualitative and Quantitative Analysis and Implications for Health Equity Open
Objectives: To assess patients’ demographic factors associated with declination of recommended American Society of Addiction Medicine (ASAM) Continuum levels of care and analyze patients’ self-reported reasons for declination. Methods: Thi…
View article: Indication-based electronic prescribing intervention reduces unnecessary meropenem use in a safety-net hospital: a quasi-experimental study
Indication-based electronic prescribing intervention reduces unnecessary meropenem use in a safety-net hospital: a quasi-experimental study Open
This quasi-experimental before-and-after intervention study evaluated an indication-based electronic prescribing alert in a 450-bed tertiary care hospital. Implementation reduced meropenem use by 41% without compromising patient safety, de…
View article: Linkja: Open Source Privacy-Preserving Record Linkage Tool
Linkja: Open Source Privacy-Preserving Record Linkage Tool Open
ObjectiveTo introduce Linkja, an open-source, certified, Privacy-Preserving Record Linkage (PPRL) tool with the primary objective of facilitating secure and efficient record linkage across diverse datasets, while preserving individual priv…
View article: Accuracy of <i>ICD-10</i> Diagnostic Codes for Identifying Housing Instability
Accuracy of <i>ICD-10</i> Diagnostic Codes for Identifying Housing Instability Open
This cohort study assesses the performance of International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) Z59 codes for identifying housing instability during health care encounters.
View article: Preventive Service Usage and New Chronic Disease Diagnoses: Using PCORnet Data to Identify Emerging Trends, United States, 2018–2022
Preventive Service Usage and New Chronic Disease Diagnoses: Using PCORnet Data to Identify Emerging Trends, United States, 2018–2022 Open
Among over 30 million patients receiving care during 2018 through 2022, use of preventive services and new diagnoses of chronic disease declined in 2020 and then rebounded, with some remaining health debt. These data highlight opportunitie…
View article: A Comparison of Variable Input Strategies used for Risk-adjustment Models of Antimicrobial Use
A Comparison of Variable Input Strategies used for Risk-adjustment Models of Antimicrobial Use Open
Background: External comparisons of antimicrobial use (AU) may be more informative if adjusted for encounter characteristics. Optimal methods to define input variables for encounter-level risk-adjustment models of AU are not established. M…
View article: Application of a Model Using Prior Healthcare Information to Predict Multidrug-Resistant Organism (MDRO) Carriage
Application of a Model Using Prior Healthcare Information to Predict Multidrug-Resistant Organism (MDRO) Carriage Open
Background: Early identification of patients colonized with MDROs can help healthcare facilities improve infection control and treatment. We evaluated whether a model previously validated to predict carbapenem-resistant Enterobacterales (C…
View article: Using Social Vulnerability Indices to Predict Priority Areas for Prevention of Sudden Unexpected Infant Death in Cook County, IL: Cross-Sectional Study
Using Social Vulnerability Indices to Predict Priority Areas for Prevention of Sudden Unexpected Infant Death in Cook County, IL: Cross-Sectional Study Open
Background The incidence of sudden unexpected infant death (SUID) in the United States has persisted at roughly the same level since the mid-2000s, despite intensive prevention efforts around safe sleep. Disparities in outcomes across raci…
View article: Association Between Hypertension and Diabetes Control and COVID‐19 Severity: National Patient‐Centered Clinical Research Network, United States, March 2020 to February 2022
Association Between Hypertension and Diabetes Control and COVID‐19 Severity: National Patient‐Centered Clinical Research Network, United States, March 2020 to February 2022 Open
Background Hypertension and diabetes are associated with increased COVID‐19 severity. The association between level of control of these conditions and COVID‐19 severity is less well understood. Methods and Results This retrospective cohort…
View article: Evolving availability and standardization of patient attributes for matching
Evolving availability and standardization of patient attributes for matching Open
Variation in availability, format, and standardization of patient attributes across health care organizations impacts patient-matching performance. We report on the changing nature of patient-matching features available from 2010–2020 acro…
View article: Layered Screening and Contact-Limiting Interventions Are Necessary to Reduce SARS-Cov-2 Outbreak Risks in Large Urban Jails
Layered Screening and Contact-Limiting Interventions Are Necessary to Reduce SARS-Cov-2 Outbreak Risks in Large Urban Jails Open
Highly transmissible infections with short serial intervals, such as SARS-Cov-2 and influenza, can quickly overwhelm healthcare resources in institutional settings such as jails. We assessed the impact of intake screening measures on the r…
View article: Using Social Vulnerability Indices to Predict Priority Areas for Prevention of Sudden Unexpected Infant Death in Cook County, IL: Cross-Sectional Study (Preprint)
Using Social Vulnerability Indices to Predict Priority Areas for Prevention of Sudden Unexpected Infant Death in Cook County, IL: Cross-Sectional Study (Preprint) Open
BACKGROUND Incidence of Sudden Unexpected Infant Death (SUID) in the United States has persisted at roughly the same level since the mid-2000’s despite intensive prevention efforts. Disparities in outcomes across racial/socioeconomic line…
View article: Author response: Quantifying healthcare-acquired coronavirus disease 2019 (COVID-19) in hospitalized patients: A closer look
Author response: Quantifying healthcare-acquired coronavirus disease 2019 (COVID-19) in hospitalized patients: A closer look Open
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View article: Racial and Ethnic Disparities in Outpatient Treatment of COVID-19 ― United States, January–July 2022
Racial and Ethnic Disparities in Outpatient Treatment of COVID-19 ― United States, January–July 2022 Open
In December 2021 and early 2022, four medications received emergency use authorization (EUA) by the Food and Drug Administration for outpatient treatment of mild-to-moderate COVID-19 in patients who are at high risk for progressing to seve…
View article: Computing antimicrobial use/antimicrobial resistance ratios: A novel way to assess inpatient antimicrobial utilization using current National Healthcare Safety Network metrics
Computing antimicrobial use/antimicrobial resistance ratios: A novel way to assess inpatient antimicrobial utilization using current National Healthcare Safety Network metrics Open
Background Current methods for benchmarking inpatient antimicrobial use (AU) could benefit from combining AU with antimicrobial resistance (AR) information to provide metrics benchmarked to microbiological data; this may yield more instruc…
View article: Preliminary comparison of gun homicide deaths for non-probation and probation clients.
Preliminary comparison of gun homicide deaths for non-probation and probation clients. Open
ObjectiveTo measure a baseline rate of gun homicide deaths for adults on probation in Cook County, Illinois, USA. To compare this rate to the rates for the population of the City of Chicago and for all of Cook County, which includes Chicag…
View article: Hospital-acquired coronavirus disease 2019 (COVID-19) among patients of two acute-care hospitals: Implications for surveillance
Hospital-acquired coronavirus disease 2019 (COVID-19) among patients of two acute-care hospitals: Implications for surveillance Open
Objectives: We quantified hospital-acquired coronavirus disease 2019 (COVID-19) during the early phases of the pandemic, and we evaluated solely temporal determinations of hospital acquisition. Design: Retrospective observational study dur…
View article: Genomic Epidemiology Suggests Community Origins of Healthcare-Associated USA300 Methicillin-Resistant <i>Staphylococcus aureus</i>
Genomic Epidemiology Suggests Community Origins of Healthcare-Associated USA300 Methicillin-Resistant <i>Staphylococcus aureus</i> Open
Background Hospital-onset (HO) methicillin-resistant Staphylococcus aureus (MRSA) infections have declined over the past decade due to infection control strategies; community-onset (CO) and healthcare-associated community-onset (HACO) MRSA…
View article: Prevalence of Select New Symptoms and Conditions Among Persons Aged Younger Than 20 Years and 20 Years or Older at 31 to 150 Days After Testing Positive or Negative for SARS-CoV-2
Prevalence of Select New Symptoms and Conditions Among Persons Aged Younger Than 20 Years and 20 Years or Older at 31 to 150 Days After Testing Positive or Negative for SARS-CoV-2 Open
In this cohort study, among persons hospitalized after a positive SARS-CoV-2 test result, diagnoses of certain symptoms and conditions were higher than among those with a negative test result. Health care professionals should be aware of s…
View article: Stopping Hospital Infections With Environmental Services (SHINE): A Cluster-randomized Trial of Intensive Monitoring Methods for Terminal Room Cleaning on Rates of Multidrug-resistant Organisms in the Intensive Care Unit
Stopping Hospital Infections With Environmental Services (SHINE): A Cluster-randomized Trial of Intensive Monitoring Methods for Terminal Room Cleaning on Rates of Multidrug-resistant Organisms in the Intensive Care Unit Open
Background Multidrug-resistant organisms (MDROs) frequently contaminate hospital environments. We performed a multicenter, cluster-randomized, crossover trial of 2 methods for monitoring of terminal cleaning effectiveness. Methods Six inte…
View article: Racial and Ethnic Disparities in Receipt of Medications for Treatment of COVID-19 — United States, March 2020–August 2021
Racial and Ethnic Disparities in Receipt of Medications for Treatment of COVID-19 — United States, March 2020–August 2021 Open
The COVID-19 pandemic has magnified longstanding health care and social inequities, resulting in disproportionately high COVID-19-associated illness and death among members of racial and ethnic minority groups (1). Equitable use of effecti…
View article: 399. Epidemiology of Laboratory-identified Late-onset SARS-CoV-2 Positivity in Two Large, Urban, Acute-Care Hospitals: Implications for Surveillance of Hospital-Acquired COVID-19
399. Epidemiology of Laboratory-identified Late-onset SARS-CoV-2 Positivity in Two Large, Urban, Acute-Care Hospitals: Implications for Surveillance of Hospital-Acquired COVID-19 Open
Background Laboratory identification (Lab-ID) of late-onset SARS-CoV-2 positive tests during a hospital stay is a potential public health surveillance approach for hospital-acquired COVID-19. However, prolonged RNA fragment shedding and in…
View article: 3. Stopping Hospital Infections with Environmental Services (SHINE): A Cluster-Randomized Trial of Intensive Monitoring Methods for Terminal Room Cleaning on Rates of Multidrug-Resistant Organisms (MDROs) in the Intensive Care Unit (ICU)
3. Stopping Hospital Infections with Environmental Services (SHINE): A Cluster-Randomized Trial of Intensive Monitoring Methods for Terminal Room Cleaning on Rates of Multidrug-Resistant Organisms (MDROs) in the Intensive Care Unit (ICU) Open
Background MDROs frequently contaminate hospital environments. We performed a multicenter cluster-randomized, crossover trial of two methods for intensive monitoring of terminal cleaning effectiveness at reducing infection and colonization…
View article: Disparities and Temporal Trends in COVID-19 Exposures and Mitigating Behaviors Among Black and Hispanic Adults in an Urban Setting
Disparities and Temporal Trends in COVID-19 Exposures and Mitigating Behaviors Among Black and Hispanic Adults in an Urban Setting Open
In this survey study of adults in a large US city, public health messaging improved preventive behaviors over time but lagged among Hispanic participants; messaging tailored to Hispanic communities, especially for mask use, should be prior…
View article: Spatial, Ecologic, and Clinical Epidemiology of Community-Onset, Ceftriaxone-Resistant <i>Enterobacteriaceae</i>, Cook County, Illinois, USA
Spatial, Ecologic, and Clinical Epidemiology of Community-Onset, Ceftriaxone-Resistant <i>Enterobacteriaceae</i>, Cook County, Illinois, USA Open
We performed a spatial and mixed ecologic study of community-onset Enterobacteriaceae isolates collected from a public healthcare system in Cook County, Illinois, USA. Individual-level data were collected from the electronic medical record…
View article: Joining Health Care and Homeless Data Systems Using Privacy-Preserving Record-Linkage Software
Joining Health Care and Homeless Data Systems Using Privacy-Preserving Record-Linkage Software Open
Joining Health Care and Homeless Data Systems Using Privacy-Preserving Record-Linkage Software William E. TrickMD, Jennifer C. HillMCP, Peter ToepferMS, Fred RachmanMD, Beth HorwitzMA, and Abel KhoMD, MS Affiliation William E. Trick is wit…
View article: Effect of the Affordable Care Act on diabetes care at major health centers: newly detected diabetes and diabetes medication management
Effect of the Affordable Care Act on diabetes care at major health centers: newly detected diabetes and diabetes medication management Open
The adoption of the Affordable Care Act (ACA)1 in the USA expanded health insurance for low-income Americans and took two main forms: Medicaid expansion in some states and subsidized private health insurance through insurance exchanges ava…