William F. McIntyre
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View article: Recurrence of Postoperative Atrial Fibrillation After Cardiac Surgery: Insights from a Tertiary Follow-Up Clinic
Recurrence of Postoperative Atrial Fibrillation After Cardiac Surgery: Insights from a Tertiary Follow-Up Clinic Open
View article: Monitoring time-to-detection of recurrent atrial fibrillation in patients with transient new-onset atrial fibrillation detected initially during hospitalization for noncardiac surgery or medical illness
Monitoring time-to-detection of recurrent atrial fibrillation in patients with transient new-onset atrial fibrillation detected initially during hospitalization for noncardiac surgery or medical illness Open
In patients with transient new-onset AF during hospitalization for another reason, the rate of detection of recurrent AF increased with longer monitoring durations. Approximately 80 % of diagnoses were made after 2 days of monitoring; the …
View article: Association Between Electrocardiographic Changes and Myocardial Injury or Death after Cardiac Surgery
Association Between Electrocardiographic Changes and Myocardial Injury or Death after Cardiac Surgery Open
After cardiac surgery, potential ischemic ECG changes are common and have divergent associations with mortality. ST depression was associated with a higher risk of death, whereas new Q waves and T-wave inversions were associated with a low…
View article: Cost-effectiveness of apixaban vs. aspirin for the reduction of thrombo-embolism in high-risk patients with device-detected atrial fibrillation: insights from the ARTESiA trial
Cost-effectiveness of apixaban vs. aspirin for the reduction of thrombo-embolism in high-risk patients with device-detected atrial fibrillation: insights from the ARTESiA trial Open
Aims Apixaban was superior to aspirin for the prevention of stroke or systemic embolism in participants with subclinical atrial fibrillation (SCAF) in the Apixaban for the Reduction of Thromboembolism in Patients With Device-Detected Subcl…
View article: Variation in Availability of Continuous Ambulatory Electrocardiographic Monitors Across Canadian Provinces
Variation in Availability of Continuous Ambulatory Electrocardiographic Monitors Across Canadian Provinces Open
View article: Comparison of total event analysis and first event analysis in relation to heterogeneity in cardiovascular trials
Comparison of total event analysis and first event analysis in relation to heterogeneity in cardiovascular trials Open
ORIGIN (NCT00069784), COMPASS (NCT01776424), TRANSCEND (NCT00153101).
View article: Alcohol Intake and Cardiovascular Outcomes in Patients With Atrial Fibrillation: <scp>RE</scp>‐<scp>LY AF</scp> Registry Analysis
Alcohol Intake and Cardiovascular Outcomes in Patients With Atrial Fibrillation: <span>RE</span>‐<span>LY AF</span> Registry Analysis Open
Background Alcohol intake increases recurrence of atrial fibrillation (AF), but its relationship with cardiovascular outcomes is less well characterized. We aimed to study the association between different levels of alcohol intake and card…
View article: Polygenic risk scores for risk prediction of atrial fibrillation in cardiac surgery patients: Insights from the prospective, multinational VISION cardiac surgery cohort
Polygenic risk scores for risk prediction of atrial fibrillation in cardiac surgery patients: Insights from the prospective, multinational VISION cardiac surgery cohort Open
Background New-onset postoperative atrial fibrillation (POAF) complicates 1 in 3 cardiac surgeries and is associated with morbidity, mortality and clinical AF in long-term follow-up. Clinical risk scores have modest performance for predict…
View article: Early recurrence of atrial arrhythmia and healthcare utilization during the 8-week blanking period following catheter ablation of atrial fibrillation
Early recurrence of atrial arrhythmia and healthcare utilization during the 8-week blanking period following catheter ablation of atrial fibrillation Open
Background The 2024 EHRA/HRS/APHRS/LAHRS expert consensus statement proposed an 8-week "blanking period" for clinical trials involving catheter ablation of atrial fibrillation (AF), in which recurrences are not seen as a failure of treatme…
View article: Incidence and predictors of major bleeding among patients receiving apixaban or aspirin for subclinical atrial fibrillation: insights from the ARTESiA sub-analysis
Incidence and predictors of major bleeding among patients receiving apixaban or aspirin for subclinical atrial fibrillation: insights from the ARTESiA sub-analysis Open
Background ARTESiA (Apixaban for the Reduction of Thrombo-Embolism in Patients with Device-Detected Sub-Clinical Atrial Fibrillation) was a randomized double-blind, double-dummy trial which showed that apixaban, compared with aspirin, redu…
View article: Reliability of resting heart rate measurements in atrial fibrillation
Reliability of resting heart rate measurements in atrial fibrillation Open
Background Resting heart rate in atrial fibrillation (AF) is a commonly used therapeutic target, but no studies have evaluated whether resting heart rates in AF are reliable over repeated measurements. We aimed to determine the reliability…
View article: Detailed analysis of PAC characteristics in ambulatory ECG data can improve atrial fibrillation risk prediction
Detailed analysis of PAC characteristics in ambulatory ECG data can improve atrial fibrillation risk prediction Open
Introduction Premature atrial complexes (PACs) are associated with atrial fibrillation (AF) risk, but also common in the general population. The origin and mechanism through which PACs arise lead to different electrocardiographic presentat…
View article: Smoking, Colchicine and Postoperative Outcomes in Thoracic Surgery: Post Hoc Analysis of the COP-AF Randomized Controlled Trial
Smoking, Colchicine and Postoperative Outcomes in Thoracic Surgery: Post Hoc Analysis of the COP-AF Randomized Controlled Trial Open
NCT03310125.
View article: Polygenic Risk Scores in Myocardial Injury After Noncardiac Surgery
Polygenic Risk Scores in Myocardial Injury After Noncardiac Surgery Open
View article: Reply to García-Villarreal
Reply to García-Villarreal Open
View article: Association of Frailty With Clinical Outcomes in Patients Receiving Primary Prevention Implantable Cardioverter Defibrillators: A Prospective Cohort Study
Association of Frailty With Clinical Outcomes in Patients Receiving Primary Prevention Implantable Cardioverter Defibrillators: A Prospective Cohort Study Open
Background Frailty predisposes individuals to morbidity and mortality. Increasing numbers of elderly and comorbid individuals are undergoing primary prevention implantable cardioverter defibrillator (ICD) device placement. Little is known …
View article: Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography
Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography Open
View article: Detection and management of postoperative atrial fibrillation after coronary artery bypass grafting or non-cardiac surgery: a survey by the AF-SCREEN International Collaboration
Detection and management of postoperative atrial fibrillation after coronary artery bypass grafting or non-cardiac surgery: a survey by the AF-SCREEN International Collaboration Open
We developed a survey to describe current practice on the detection and management of new-onset postoperative atrial fibrillation (POAF) occurring after coronary artery bypass grafting (CABG) or non-cardiac surgery. We e-mailed an online a…
View article: Author's Reply to “Digital Devices for Arrhythmia Detection: What Is Still Missing?”
Author's Reply to “Digital Devices for Arrhythmia Detection: What Is Still Missing?” Open
View article: Rhythm vs Rate Control Strategies for Perioperative Atrial Fibrillation After Noncardiac Surgery: A Systematic Review and Meta-analysis
Rhythm vs Rate Control Strategies for Perioperative Atrial Fibrillation After Noncardiac Surgery: A Systematic Review and Meta-analysis Open
A rhythm control strategy was associated with greater success rates for conversion to sinus rhythm compared with a rate control or no treatment strategy. However, the observational studies were of low quality and only 1 small RCT was ident…
View article: Clinical significance of a new diagnosis of atrial fibrillation in patients with vascular disease
Clinical significance of a new diagnosis of atrial fibrillation in patients with vascular disease Open
In patients with vascular disease, a new diagnosis of AF was associated with a marked increase in risk of adverse outcomes, especially hospitalization for heart failure.
View article: Prophylactic ablation during cardiac surgery in patients without atrial fibrillation: a systematic review and meta-analysis of randomized trials
Prophylactic ablation during cardiac surgery in patients without atrial fibrillation: a systematic review and meta-analysis of randomized trials Open
OBJECTIVES Atrial fibrillation is the most common complication of cardiac surgery and occurs frequently in patients without a history of the arrhythmia. We conducted a systematic review and meta-analysis of randomized controlled trials to …
View article: Physician Preferences in Using Novel Digital Devices for the Management of Atrial Fibrillation—A DAS‐CAM III Survey
Physician Preferences in Using Novel Digital Devices for the Management of Atrial Fibrillation—A DAS‐CAM III Survey Open
Aim A recent European Heart Rhythm Association (EHRA) practical guide provides guidance on the use of novel digital devices for heart rhythm analysis using either electrocardiogram (ECG) or photoplethysmography (PPG) technology for the dia…
View article: Research priorities for the study of atrial fibrillation during acute and critical illness: recommendations from the Symposium on Atrial Fibrillation in Acute and Critical Care
Research priorities for the study of atrial fibrillation during acute and critical illness: recommendations from the Symposium on Atrial Fibrillation in Acute and Critical Care Open
View article: A sub-study of the POISE-3 randomized trial examined effects of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of acute kidney injury
A sub-study of the POISE-3 randomized trial examined effects of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of acute kidney injury Open
In this pre-specified sub-study of the POISE-3 trial, we examined the effect of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of postoperative acute kidney injury (AKI). Altogether, 730…
View article: Mineralocorticoid receptor antagonists for atrial fibrillation prevention: effective solution or empty promise?
Mineralocorticoid receptor antagonists for atrial fibrillation prevention: effective solution or empty promise? Open
View article: Risk of stroke with reduced dose direct oral anticoagulants vs standard dose anticoagulation after cardioversion of atrial fibrillation: A systematic review and meta-analysis
Risk of stroke with reduced dose direct oral anticoagulants vs standard dose anticoagulation after cardioversion of atrial fibrillation: A systematic review and meta-analysis Open
View article: Anticoagulation in device-detected atrial fibrillation with or without vascular disease: a combined analysis of the NOAH-AFNET 6 and ARTESiA trials
Anticoagulation in device-detected atrial fibrillation with or without vascular disease: a combined analysis of the NOAH-AFNET 6 and ARTESiA trials Open
Background and Aims The optimal antithrombotic therapy in patients with device-detected atrial fibrillation (DDAF) is unknown. Concomitant vascular disease can modify the benefits and risks of anticoagulation. Methods These pre-specified a…
View article: A Systematic Review of Ongoing Registered Research Studies on Post-Operative Atrial Fibrillation after Cardiac Surgery
A Systematic Review of Ongoing Registered Research Studies on Post-Operative Atrial Fibrillation after Cardiac Surgery Open
Background/Objectives: New-onset atrial fibrillation (AF) after cardiac surgery is associated with patient-important outcomes. Uncertainty persists regarding its prevention, detection, and management. This review seeks to identify, compile…
View article: Temporal Trends in the Management Practices of Clinically Important Perioperative Atrial Fibrillation After Noncardiac Surgery
Temporal Trends in the Management Practices of Clinically Important Perioperative Atrial Fibrillation After Noncardiac Surgery Open