William J. Panenka
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View article: Concussion Recognition: A Guide for Parents and Coaches
Concussion Recognition: A Guide for Parents and Coaches Open
View article: Diffusion tensor imaging after COVID-19 infection: A systematic review
Diffusion tensor imaging after COVID-19 infection: A systematic review Open
A review of the literature indicates that the heterogeneity of findings regarding dMRI metrics after the resolution of the acute phase of COVID-19 illness may be due in part to the severity of COVID-19 illness and the time between COVID-19…
View article: Quantitative brain volume differences between COVID-19 patients and non-COVID-19 volunteers: A systematic review
Quantitative brain volume differences between COVID-19 patients and non-COVID-19 volunteers: A systematic review Open
A systematic review of the literature indicates that COVID-19 illness severity may explain some of the heterogeneity in brain volume differences between COVID-19 patients and healthy volunteers. More longitudinal follow-up studies are need…
View article: Metabolomic in severe traumatic brain injury: exploring primary, secondary injuries, diagnosis, and severity
Metabolomic in severe traumatic brain injury: exploring primary, secondary injuries, diagnosis, and severity Open
View article: Pilot feasibility randomised controlled trial of cognitive–behavioural therapy for functional cognitive disorder after concussion
Pilot feasibility randomised controlled trial of cognitive–behavioural therapy for functional cognitive disorder after concussion Open
Background Functional cognitive disorder (FCD) may be common after a concussion, and no evidence-based treatment options are available. The current study evaluated the feasibility of a novel cognitive–behavioural therapy (CBT) protocol tai…
View article: Differences in brain structure and cognitive performance between patients with long-COVID and those with normal recovery
Differences in brain structure and cognitive performance between patients with long-COVID and those with normal recovery Open
Differences in diffusivity between long-COVID and normal recovery groups were found on only one DTI metric. This could represent subtle areas of pathology such as gliosis or edema, but the small effect sizes and non-specific nature of the …
View article: Post-discharge health-related quality of life, cognitive function, disability, risk of post-traumatic stress disorder, and depression amongst the survivors of veno-venous extracorporeal membrane oxygenation (VV-ECMO) during the COVID-19 pandemic: a nested cohort study protocol
Post-discharge health-related quality of life, cognitive function, disability, risk of post-traumatic stress disorder, and depression amongst the survivors of veno-venous extracorporeal membrane oxygenation (VV-ECMO) during the COVID-19 pandemic: a nested cohort study protocol Open
Background Veno-venous extra-corporeal membrane oxygenation (VV-ECMO) is a form of mechanical respiratory support for critically ill patients with severe acute respiratory distress syndrome (ARDS). Using a large intravenous line in a close…
View article: Diagnostic Accuracy of Mental Health Screening Tools After Mild Traumatic Brain Injury
Diagnostic Accuracy of Mental Health Screening Tools After Mild Traumatic Brain Injury Open
Importance Mental health disorders are common after mild traumatic brain injury (mTBI) and likely exacerbate postconcussive symptoms and disability. Early detection could improve clinical outcomes, but the accuracy of mental health screeni…
View article: Predicting Outcomes in Patients with Diffuse Axonal Injury: External Validation of the Widely Used Prognostic Instruments
Predicting Outcomes in Patients with Diffuse Axonal Injury: External Validation of the Widely Used Prognostic Instruments Open
AIM: Accurate prognosis of diffuse axonal injury (DAI) is important in directing clinical care, allocating resources appropriately, and communicating with families and surrogate decision-makers. METHODS: A study was conducted on patients w…
View article: A scoping review of the effects of mushroom and fungus extracts in rodent models of depression and tests of antidepressant activity
A scoping review of the effects of mushroom and fungus extracts in rodent models of depression and tests of antidepressant activity Open
One of the most important developments in psychopharmacology in the past decade has been the emergence of novel treatments for mood disorders, such as psilocybin for treatment-resistant depression. Psilocybin is most commonly found in diff…
View article: Graded Exposure Therapy for Fear Avoidance Behaviour After Concussion (GET FAB): protocol for a multisite Canadian randomised controlled trial
Graded Exposure Therapy for Fear Avoidance Behaviour After Concussion (GET FAB): protocol for a multisite Canadian randomised controlled trial Open
Introduction Persistent symptoms after mild traumatic brain injury (mTBI) negatively affect daily functioning and quality of life. Fear avoidance behaviour, a coping style in which people avoid or escape from activities or situations that …
View article: The connection between homelessness and dementia
The connection between homelessness and dementia Open
Homelessness, a worldwide concern, reflects societal inequalities. Social, structural, cultural, and economic disadvantages contribute to poorer health and earlier mortality in homeless populations.1Fazel S Geddes JR Kushel M The health of…
View article: Clinical practice guideline recommendations to improve the mental health of adult trauma patients: protocol for a systematic review
Clinical practice guideline recommendations to improve the mental health of adult trauma patients: protocol for a systematic review Open
Introduction Mental disorders are common in adult patients with traumatic injuries. To limit the burden of poor psychological well-being in this population, recognised authorities have issued recommendations through clinical practice guide…
View article: Heterogeneous neuroimaging findings across substance use disorders localize to a common brain network
Heterogeneous neuroimaging findings across substance use disorders localize to a common brain network Open
Substance use disorders are associated with neuroimaging abnormalities, but results are heterogeneous across studies and vary across substances, and the causal interpretation of these abnormalities is unknown. We have used network mapping …
View article: Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months
Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months Open
Background Prognostication is very important to clinicians and families during the early management of severe traumatic brain injury (sTBI), however, there are no gold standard biomarkers to determine prognosis in sTBI. As has been demonst…
View article: Exploring medical cannabis use in individuals with a traumatic brain injury
Exploring medical cannabis use in individuals with a traumatic brain injury Open
Aim: Traumatic brain injury (TBI) is a common neurological condition, which can present with a wide range of neuropsychological symptoms. Treating this broad spectrum of symptoms represents a significant medical challenge. In part because …
View article: The American Congress of Rehabilitation Medicine Diagnostic Criteria for Mild Traumatic Brain Injury
The American Congress of Rehabilitation Medicine Diagnostic Criteria for Mild Traumatic Brain Injury Open
View article: Are Younger Medical Cannabis Users at Risk? Comparing Patterns of Use and Mental Health in Younger and Older Medical Cannabis Dispensary Users
Are Younger Medical Cannabis Users at Risk? Comparing Patterns of Use and Mental Health in Younger and Older Medical Cannabis Dispensary Users Open
While there has been a considerable amount of research on recreational cannabis use in youth to date, much less is known about patterns of medical cannabis use in youth. Adult medical versus recreational cannabis users may differ in how th…
View article: Metabolomic profiles in serum predict global functional neurological outcome at 3 and 12 months and death at 3 months following severe traumatic brain injury
Metabolomic profiles in serum predict global functional neurological outcome at 3 and 12 months and death at 3 months following severe traumatic brain injury Open
Background Prognostication is very important to clinicians and families during the early management of severe traumatic brain injury (sTBI), however, there are no gold standard biomarkers to determine prognosis in sTBI. As has been demonst…
View article: Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared with the general population
Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared with the general population Open
Background Homeless or precariously housed individuals live with poor health and experience premature mortality compared with the general population, yet little is known about age-related brain changes among these individuals. We evaluated…
View article: The Utility of Blood Based Biomarkers in Detecting Neurological Complications of COVID‐19 in Critically Ill Patients
The Utility of Blood Based Biomarkers in Detecting Neurological Complications of COVID‐19 in Critically Ill Patients Open
Background Neurological and neuropsychiatric complications have been documented in patients with COVID‐19. This study aims to investigate the utility of two neurological blood‐based biomarkers to predict neurological complications and mort…
View article: Factors Associated with Problematic Cannabis Use in a Sample of Medical Cannabis Dispensary Users
Factors Associated with Problematic Cannabis Use in a Sample of Medical Cannabis Dispensary Users Open
The prevalence of problematic cannabis use in the community dispensary was higher than expected. Specific risk factors for problematic cannabis use may represent important areas for future intervention to ensure safer consumption for medic…
View article: Effectiveness of a guideline implementation tool for supporting management of mental health complications after mild traumatic brain injury in primary care: protocol for a randomised controlled trial
Effectiveness of a guideline implementation tool for supporting management of mental health complications after mild traumatic brain injury in primary care: protocol for a randomised controlled trial Open
Introduction Mental health problems frequently interfere with recovery from mild traumatic brain injury (mTBI) but are under-recognised and undertreated. Consistent implementation of clinical practice guidelines for proactive detection and…
View article: Chronic Treatment With Psilocybin Decreases Changes in Body Weight in a Rodent Model of Obesity
Chronic Treatment With Psilocybin Decreases Changes in Body Weight in a Rodent Model of Obesity Open
Background There are currently relatively few effective pharmacological treatments for obesity, and existing ones may be associated with limiting side-effects. In the search for novel anti-obesity agents, drugs that modify central serotone…
View article: Traumatic brain injury in precariously housed persons: Incidence and risks
Traumatic brain injury in precariously housed persons: Incidence and risks Open
View article: Criterion validity of the brief test of adult cognition by telephone (BTACT) for mild traumatic brain injury
Criterion validity of the brief test of adult cognition by telephone (BTACT) for mild traumatic brain injury Open
There is a growing demand for remote assessment options for measuring cognition after mild traumatic brain injury (mTBI). The current study evaluated the criterion validity of the Brief Test of Adult Cognition by Telephone (BTACT) in disti…
View article: Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared to the general population
Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared to the general population Open
Importance Homeless or precariously housed individuals live with poor health and experience premature mortality compared to the general population. With an increasing average age among this demographic, syndromes associated with neurogener…
View article: Longitudinal changes in brain parenchyma due to mild traumatic brain injury during the first year after injury
Longitudinal changes in brain parenchyma due to mild traumatic brain injury during the first year after injury Open
Chronic gray matter (GM) atrophy is a known consequence of moderate and severe traumatic brain injuries but has not been consistently shown in mild traumatic brain injury (mTBI). The aim of this study was to investigate the longitudinal ef…
View article: Author response for "Longitudinal changes in brain parenchyma due to mild traumatic brain injury during the first year after injury"
Author response for "Longitudinal changes in brain parenchyma due to mild traumatic brain injury during the first year after injury" Open
View article: Psychometric properties and correlates of the Beck Depression Inventory in a community-based and homeless or precariously housed sample
Psychometric properties and correlates of the Beck Depression Inventory in a community-based and homeless or precariously housed sample Open
Background: Although homeless or precariously housed populations have a high prevalence of depression, the suitability of existing symptom measurement tools remains unknown. The present study explores the psychometric properties and correl…