William Peppard
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View article: Opioid Prescribing in Opioid-Naïve and Opioid-Exposed Mechanically Ventilated Medically Critically Ill Patients
Opioid Prescribing in Opioid-Naïve and Opioid-Exposed Mechanically Ventilated Medically Critically Ill Patients Open
Objective: Characterize opioid prescribing patterns in the ICU and post-hospital discharge in invasively mechanically ventilated (IMV) opioid-naïve and opioid-exposed patients. Design: Single-center, retrospective cohort study. Setting: Te…
View article: Clinical Impact of an Expanded MOUD Access Initiative for Patients Hospitalized With Infections From Intravenous Opioid Use
Clinical Impact of an Expanded MOUD Access Initiative for Patients Hospitalized With Infections From Intravenous Opioid Use Open
The EMAI was associated with increased MOUD uptake, reduced PDD, and fewer 30-day re-hospitalizations despite the lack of addiction medicine consultation.
View article: Pharmacogenetic Evaluation of Hospitalized Patients Requiring Naloxone for Reversal of Acute Opioid Toxicity
Pharmacogenetic Evaluation of Hospitalized Patients Requiring Naloxone for Reversal of Acute Opioid Toxicity Open
Background: Opioids are utilized for acute pain in hospitalized patients and carry the risk of unintentional toxicity. The relationship between unintentional toxicity within a hospital setting and genetic polymorphisms has not been fully e…
View article: PHarmacist Avoidance or Reductions in Medical Costs Considering Board of Pharmacy Specialties Certification (PHARM-BPS)
PHarmacist Avoidance or Reductions in Medical Costs Considering Board of Pharmacy Specialties Certification (PHARM-BPS) Open
Introduction: Clinical pharmacists bring unparalleled medication expertise, but quantifying their impact on a health system’s bottom line remains unestablished. Objective: To classify interventions by pharmacists with and without board cer…
View article: Multicenter Retrospective Review of Ketamine Use in Pediatric Intensive Care Units (Ketamine‐PICU Study)
Multicenter Retrospective Review of Ketamine Use in Pediatric Intensive Care Units (Ketamine‐PICU Study) Open
Objective . Describe continuous infusion (CI) ketamine practices in pediatric intensive care units (PICUs) and evaluate its effect on pain/sedation scores, exposure to analgesics/sedatives, and adverse effects (AEs). Methods . Multicenter,…
View article: <scp>PHarmacist</scp> avoidance or reductions in medical costs in <scp>CRITically</scp> ill adults rounding with one <scp>SERVICE</scp> compared to two or more services: <scp>PHARM‐CRIT‐SERVICE</scp>
<span>PHarmacist</span> avoidance or reductions in medical costs in <span>CRITically</span> ill adults rounding with one <span>SERVICE</span> compared to two or more services: <span>PHARM‐CRIT‐SERVICE</span> Open
Introduction Intensive care unit (ICU) pharmacists are integral members of the interdisciplinary health care team. Pharmacy staffing models vary by ICU and hospital, and clinical pharmacists may cover one ICU service or multiple services. …
View article: 1408. Increasing Access to Medications for Opioid Use Disorder in Patients Hospitalized with Severe Injection Related Infections: A Single Center Experience
1408. Increasing Access to Medications for Opioid Use Disorder in Patients Hospitalized with Severe Injection Related Infections: A Single Center Experience Open
Background Hospitalizations for severe injection related infections (SIRI) amongst persons who inject drugs (PWID) are often complicated by patient directed discharge (PDD), incomplete antibiotic treatment and 90-day readmission. Despite a…
View article: PHarmacist Avoidance or Reductions in Medical Costs in Patients Presenting the EMergency Department: PHARM-EM Study
PHarmacist Avoidance or Reductions in Medical Costs in Patients Presenting the EMergency Department: PHARM-EM Study Open
Objectives: To comprehensively classify interventions performed by emergency medicine clinical pharmacists and quantify cost avoidance generated through their accepted interventions. Design: A multicenter, prospective, observational study …
View article: Inpatient Perioperative Formulary Restriction of Intravenous Acetaminophen at Vizient Partner Hospitals: A National Survey of Pharmacists
Inpatient Perioperative Formulary Restriction of Intravenous Acetaminophen at Vizient Partner Hospitals: A National Survey of Pharmacists Open
Purpose: Despite potential benefits of intravenous (i.v.) administration of acetaminophen (APAP), consistent outcome data are lacking. This, combined with the higher acquisition cost of the drug, has led to variation in i.v. APAP managemen…
View article: Continuous Etomidate Infusion for the Management of Severe Cushing Syndrome: Validation of a Standard Protocol
Continuous Etomidate Infusion for the Management of Severe Cushing Syndrome: Validation of a Standard Protocol Open
Objective Demonstrate the safety and efficacy of a standardized intravenous etomidate infusion protocol in normalizing cortisol levels in patients with severe and life-threatening hypercortisolism. Methods A retrospective case series of se…
View article: Abstract: Prolonged Antibiotic Duration Does Not Affect Surgical Site Infection Rates in Traumatic Mandible Fracture
Abstract: Prolonged Antibiotic Duration Does Not Affect Surgical Site Infection Rates in Traumatic Mandible Fracture Open
INTRODUCTION: The appropriate duration of antibiotic (Abx) therapy for surgical site infection (SSI) prevention in traumatic mandibular fracture repair is unknown. Data regarding the appropriate duration of therapy are lacking in this pati…
View article: Association between Pre-Operative Cefazolin Dose and Surgical Site Infection in Obese Patients
Association between Pre-Operative Cefazolin Dose and Surgical Site Infection in Obese Patients Open
In otherwise similar obese surgical patients weighing ≥100 kg, the administration of a pre-operative cefazolin two gram dose is associated with a similar rate of SSI compared with patients who received a three gram dose.
View article: CLINICALLY SIGNIFICANT REMOVAL OF LEVETIRACETAM IN A PATIENT ON CONTINUOUS VENOVENOUS HEMOFILTRATION
CLINICALLY SIGNIFICANT REMOVAL OF LEVETIRACETAM IN A PATIENT ON CONTINUOUS VENOVENOUS HEMOFILTRATION Open
International audience
View article: New developments in the treatment of acute bacterial skin and skin structure infections: considerations for the effective use of dalbavancin
New developments in the treatment of acute bacterial skin and skin structure infections: considerations for the effective use of dalbavancin Open
Dalbavancin, an intravenous glycopeptide, was approved by the US Food and Drug Administration in May 2014 for use in adult patients with acute bacterial skin and skin structure infections. The recommended dosing regimen for effective use o…