Rogério Agenor de Araújo
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View article: Dynamic study of multi-planets in binary systems
Dynamic study of multi-planets in binary systems Open
Exoplanets are common in binary systems. There are 140 known exoplanets in these systems, about 10 of which orbit binary systems containing an evolved star, such as a white dwarf (WD) or subdwarf (see the NASA Exoplanet Archive at http://e…
View article: Circulating chemokines and leukocytes and their impact on breast cancer prognosis
Circulating chemokines and leukocytes and their impact on breast cancer prognosis Open
Risk stratification in BC patients is grounded in tumor staging and immunohistochemistry. However, systemic inflammatory responses, including cytokine- and chemokine-mediated signaling of neutrophils and lymphocytes, play a critical role i…
View article: Survival differences between women and men in the non-reproductive cancers: Results from a matched analysis of the surveillance, epidemiology, and end-results program
Survival differences between women and men in the non-reproductive cancers: Results from a matched analysis of the surveillance, epidemiology, and end-results program Open
Background Men with non-reproductive cancers have a discrepant outcome compared to women. However, they differ significantly in the incidence of cancer type and characteristics. Methods Patients with single primary cancer who were 18 years…
View article: Epidermal growth factor receptor (EGFR) expression in the serum of patients with triple-negative breast carcinoma: prognostic value of this biomarker
Epidermal growth factor receptor (EGFR) expression in the serum of patients with triple-negative breast carcinoma: prognostic value of this biomarker Open
Increased sEGFR expression in patients with TN tumours is a significant predictor of lower OS and its quantification is inexpensive and straightforward.
View article: A hierarchical approach to combine histological grade and immunohistochemical factors to identify high-risk luminal breast cancers
A hierarchical approach to combine histological grade and immunohistochemical factors to identify high-risk luminal breast cancers Open
The semi-quantitative expression of both cHR, Ki-67 proliferation index and histological grade can identify luminal breast cancer patients at greater risk of developing metastasis and death when combined in a hierarchical fashion, and coul…
View article: Prognosis value of lymphovascular invasion in patients with invasive ductal breast carcinoma according to lymph node metastasis status
Prognosis value of lymphovascular invasion in patients with invasive ductal breast carcinoma according to lymph node metastasis status Open
The presence of lymphovascular invasion is a predictor of worse prognosis in patients with invasive ductal carcinoma of the breast, even with metastatic lymph node disease (N1-N3).
View article: The benefits of trastuzumab in the treatment of HER2+ breast cancer as a function of exposure time
The benefits of trastuzumab in the treatment of HER2+ breast cancer as a function of exposure time Open
Despite showing some benefits, the protective effect derived from a suboptimal time of trastuzumab exposure is inferior to the standard course of 1 year.
View article: Corrigendum: Decreased Survival of Invasive Ductal Breast Cancer Patients With Two Macrometastatic Lymph Nodes Among Few Resected Ones: Should Current Sentinel-Lymph-Node Guidelines Be Revised?
Corrigendum: Decreased Survival of Invasive Ductal Breast Cancer Patients With Two Macrometastatic Lymph Nodes Among Few Resected Ones: Should Current Sentinel-Lymph-Node Guidelines Be Revised? Open
[This corrects the article DOI: 10.3389/fonc.2021.669890.].
View article: Decreased Survival of Invasive Ductal Breast Cancer Patients With Two Macrometastatic Lymph Nodes Among Few Resected Ones: Should Current Sentinel-Lymph-Node Guidelines Be Revised?
Decreased Survival of Invasive Ductal Breast Cancer Patients With Two Macrometastatic Lymph Nodes Among Few Resected Ones: Should Current Sentinel-Lymph-Node Guidelines Be Revised? Open
Purpose Sentinel-lymph-node (SLN) biopsy (SLB) is an efficient and safe axillary surgical approach with decreased morbidity than total axillary lymph node dissection (ALND) in initial patients (T1–T2). Current guidelines strongly suggest a…
View article: High-Grade Pleomorphic Sarcoma of the Left Atrium after Incomplete Resection and Adjuvant Chemotherapy
High-Grade Pleomorphic Sarcoma of the Left Atrium after Incomplete Resection and Adjuvant Chemotherapy Open
Introduction Primary cardiac tumors are extremely rare, found in only 0.02% of all autopsies. These tumors are malignant in only 25% of the cases, 75% of which are sarcomas, frequently affecting young people with no risk factors.² The medi…
View article: EGF (epidermal growth factor) receptor expression in blood: Prognostic biomarker in overall survival (OS) of patients with non-metastatic triple negative (TN) breast carcinoma.
EGF (epidermal growth factor) receptor expression in blood: Prognostic biomarker in overall survival (OS) of patients with non-metastatic triple negative (TN) breast carcinoma. Open
e14518 Background: EGF acts on tumor progression and its receptor can be measured by immunohistochemistry, or in the blood by immunoenzymatic method. This study quantified the expression of blood EGF receptors (bEGFR) in the molecular subt…
View article: Splicing Factors in Breast Cancer: Drivers of the Breast Tumor Fate
Splicing Factors in Breast Cancer: Drivers of the Breast Tumor Fate Open
Splicing is a critical step in gene expression, responsible for the excision of introns, producing the mature form of mRNA. Also, the possible arrangements of exons enlarge the proteome in 80%, enabling one gene to encode more than one pro…
View article: Shorter Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia: The Experience of the Prospective, Randomized Brazilian GBTLI ALL-93 Protocol
Shorter Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia: The Experience of the Prospective, Randomized Brazilian GBTLI ALL-93 Protocol Open
Six-month reduction of maintenance therapy in ALL children treated according to the GBTLI ALL-93 protocol provided the same overall outcome as 2-year duration regimen.