William Raynor
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View article: The advancement and utility of multimodal imaging in the diagnosis of degenerative disc disease
The advancement and utility of multimodal imaging in the diagnosis of degenerative disc disease Open
Degenerative disc disease (DDD) is a common spinal condition characterized by the deterioration of intervertebral discs, leading to chronic back pain and reduced mobility. While magnetic resonance imaging (MRI) has long been the standard f…
View article: PSMA PET/CT Incidental Detection of Tumor Thrombus From Unsuspected Renal Cell Carcinoma and Comparison with FDG PET/CT
PSMA PET/CT Incidental Detection of Tumor Thrombus From Unsuspected Renal Cell Carcinoma and Comparison with FDG PET/CT Open
Clear cell renal cell carcinoma (ccRCC) is typically prostate‐specific membrane antigen (PSMA)‐avid, likely related to PSMA expression in the tumor neovasculature, suggesting a potential role for evaluation by PSMA PET/CT. We describe a 77…
View article: Maxillary sinus inflammation assessment using FDG-PET/CT in head and neck cancer patients with photon, proton, and combined radiation therapy
Maxillary sinus inflammation assessment using FDG-PET/CT in head and neck cancer patients with photon, proton, and combined radiation therapy Open
Our findings demonstrate that photon RT leads to significant increases in maxillary sinus SUVmean as measured by FDG-PET/CT, while proton and mixed photon/proton RT do not show statistically significant changes. These preliminary results s…
View article: Metastatic Merkel Cell Carcinoma Incidentally Detected on PSMA PET/CT in a Patient With Metastatic Prostate Cancer
Metastatic Merkel Cell Carcinoma Incidentally Detected on PSMA PET/CT in a Patient With Metastatic Prostate Cancer Open
Positron emission tomography (PET) radiotracers targeting prostate‐specific membrane antigen (PSMA) are now widely used in the evaluation of prostate cancer. However, PSMA activity has also been described in several nonprostatic malignanci…
View article: Carcinoid crisis in Lutetium-177-Dotatate therapy of neuroendocrine tumors: an overview of pathophysiology, risk factors, recognition, and treatment
Carcinoid crisis in Lutetium-177-Dotatate therapy of neuroendocrine tumors: an overview of pathophysiology, risk factors, recognition, and treatment Open
Purpose Lutetium-177-Dotatate (Lutathera ® ) is a combined radionuclide-peptide that is FDA-approved for the treatment of well-differentiated, somatostatin receptor-positive, gastroenteropancreatic neuroendocrine tumors. Carcinoid crisis i…
View article: FDG-PET in the diagnosis of primary progressive aphasia: a systematic review
FDG-PET in the diagnosis of primary progressive aphasia: a systematic review Open
Primary progressive aphasia (PPA) is a disease known to affect the frontal and temporal regions of the left hemisphere. PPA is often an indication of future development of dementia, specifically semantic dementia (SD) for frontotemporal de…
View article: FDG altered biodistribution in white adipose tissue, a rare entity: case report and review of the literature
FDG altered biodistribution in white adipose tissue, a rare entity: case report and review of the literature Open
Purpose Altered 18 F-fluorodeoxyglucose (FDG) biodistribution due to patient factors such as exercise and inadequate fasting are well established causes of limited diagnostic efficacy. In addition, medications such as G-CSF are known to af…
View article: Brain FDG-PET imaging in long COVID patients
Brain FDG-PET imaging in long COVID patients Open
International audience
View article: Intraoperative OCT-Guided Volumetric Measurements of Subretinal Therapy Delivery in Humans
Intraoperative OCT-Guided Volumetric Measurements of Subretinal Therapy Delivery in Humans Open
Purpose: To evaluate a recently developed technique using intraoperative optical coherence tomography (OCT) to measure subretinal tissue plasminogen activator (tPA) volumes in patients with submacular hemorrhage secondary to exudative age-…
View article: Role of PET/CT in diagnosing and monitoring disease activity in rheumatoid arthritis: a review
Role of PET/CT in diagnosing and monitoring disease activity in rheumatoid arthritis: a review Open
Rheumatoid Arthritis (RA) is a systemic inflammatory disorder that commonly presents with polyarthritis but can have multisystemic involvement and complications, leading to increased morbidity and mortality. The diagnosis of RA continues t…
View article: Somatostatin Receptor PET Imaging of Physiologic and Benign Processes: Implications for Image Interpretation, Avoiding Pitfalls, and Clinical Applications
Somatostatin Receptor PET Imaging of Physiologic and Benign Processes: Implications for Image Interpretation, Avoiding Pitfalls, and Clinical Applications Open
View article: Current uses and understanding of PET imaging in cardiac sarcoidosis
Current uses and understanding of PET imaging in cardiac sarcoidosis Open
Sarcoidosis is a systemic disease with unclear etiology characterized by the accumulation of noncaseating, immune granulomas in affected tissues. In cardiac sarcoidosis (CS), white blood cells build up within the heart muscles, causing car…
View article: 18F-FDG-PET and other imaging modalities in the diagnosis and management of inflammatory bowel disease
18F-FDG-PET and other imaging modalities in the diagnosis and management of inflammatory bowel disease Open
Inflammatory bowel disease (IBD), which encompasses ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory condition of the gastrointestinal (GI) tract that presents complex diagnostic and management challenges. Early …
View article: Abstract 015: Pioneering NaF‐PET/CT Imaging for Early Detection of Atherosclerosis: Potential Implications for Neurointerventional Surgery
Abstract 015: Pioneering NaF‐PET/CT Imaging for Early Detection of Atherosclerosis: Potential Implications for Neurointerventional Surgery Open
Introduction Cerebrovascular disease (CVD), particularly carotid artery atherosclerosis, contributes substantially to global morbidity and mortality. The ability to precisely detect atherosclerosis is crucial, as it directly influences pat…
View article: Methods for real-time feature-guided image fusion of intrasurgical volumetric optical coherence tomography with digital microscopy: publisher’s note
Methods for real-time feature-guided image fusion of intrasurgical volumetric optical coherence tomography with digital microscopy: publisher’s note Open
This publisher’s note contains a correction to [ Biomed. Opt. Express 14 , 3308 ( 2023 ) 10.1364/BOE.488975 ].
View article: The Emerging Role of NaF-PET/CT in Detecting Vascular Microcalcification in the Pathogenesis of Neurological Dysfunction
The Emerging Role of NaF-PET/CT in Detecting Vascular Microcalcification in the Pathogenesis of Neurological Dysfunction Open
Cerebrovascular disease (CVD) is a global health concern, and early detection is crucial for effective intervention. This case report presents a 31-year-old male patient with multiple cardiac risk factors who underwent positron emission to…
View article: Longitudinal Choroidal Development in Preterm Infants
Longitudinal Choroidal Development in Preterm Infants Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
View article: 18F-FDG and 18F-NaF PET/CT Global Assessment of Large Joint Inflammation and Bone Turnover in Rheumatoid Arthritis
18F-FDG and 18F-NaF PET/CT Global Assessment of Large Joint Inflammation and Bone Turnover in Rheumatoid Arthritis Open
Rheumatoid arthritis (RA) involves chronic inflammation of synovial joints, causing pain, stiffness, and limited mobility. 18F-sodium fluoride (NaF) is a PET tracer whose uptake reflects bone turnover, while 18F-fludeoxyglucose (FDG) shows…
View article: Visualization of surgical maneuvers using intraoperative real-time volumetric optical coherence tomography
Visualization of surgical maneuvers using intraoperative real-time volumetric optical coherence tomography Open
Ophthalmic microsurgery is traditionally performed using stereomicroscopes and requires visualization and manipulation of sub-millimeter tissue structures with limited contrast. Optical coherence tomography (OCT) is a non-invasive imaging …
View article: Methods for real-time feature-guided image fusion of intrasurgical volumetric optical coherence tomography with digital microscopy
Methods for real-time feature-guided image fusion of intrasurgical volumetric optical coherence tomography with digital microscopy Open
4D-microscope-integrated optical coherence tomography (4D-MIOCT) is an emergent multimodal imaging technology in which live volumetric OCT (4D-OCT) is implemented in tandem with standard stereo color microscopy. 4D-OCT provides ophthalmic …
View article: Predicting the Efficacy of SBRT for Lung Cancer with 18F-FDG PET/CT Radiogenomics
Predicting the Efficacy of SBRT for Lung Cancer with 18F-FDG PET/CT Radiogenomics Open
Purpose: to develop a radiogenomic model on the basis of 18F-FDG PET/CT radiomics and clinical-parameter EGFR for predicting PFS stratification in lung-cancer patients after SBRT treatment. Methods: A total of 123 patients with lung cancer…
View article: The Utility of 18F-NaF-Positron Emission Tomography/Computed Tomography in Measuring the Metabolic Activity of the Aging Spine
The Utility of 18F-NaF-Positron Emission Tomography/Computed Tomography in Measuring the Metabolic Activity of the Aging Spine Open
Study Design. Cross-sectional; observational. Objectives. To determine whether sodium fluoride (NaF) positron emission tomography/computed tomography (PET/CT) can be used to monitor decreased bone turnover with aging in the spine. Backgrou…
View article: Is Imaging Bacteria with PET a Realistic Option or an Illusion?
Is Imaging Bacteria with PET a Realistic Option or an Illusion? Open
The application of [18F]-fluorodeoxyglucose ([18F]FDG) as a radiotracer to detect sites of inflammation (either due to bacterial infection or primary inflammation) has led to exploring the role of PET in visualizing bacteria directly at si…
View article: The emerging role of positron emission tomography (PET) in the management of photon radiotherapy-induced vasculitis in head and neck cancer patients
The emerging role of positron emission tomography (PET) in the management of photon radiotherapy-induced vasculitis in head and neck cancer patients Open
View article: Emerging PET Tracers in Cardiac Molecular Imaging
Emerging PET Tracers in Cardiac Molecular Imaging Open
18F-fluorodeoxyglucose (FDG) and 18F-sodium fluoride (NaF) represent emerging PET tracers used to assess atherosclerosis-related inflammation and molecular calcification, respectively. By localizing to sites with high…
View article: Effects of chimeric antigen receptor T-cell therapy on pulmonary and hepatic FDG uptake in patients with non-Hodgkin lymphoma
Effects of chimeric antigen receptor T-cell therapy on pulmonary and hepatic FDG uptake in patients with non-Hodgkin lymphoma Open
View article: Chimeric antigen receptor T-cell treatment for non-Hodgkin lymphoma: A comprehensive bone marrow evaluation with FDG PET/CT
Chimeric antigen receptor T-cell treatment for non-Hodgkin lymphoma: A comprehensive bone marrow evaluation with FDG PET/CT Open
View article: Variations in hepatic FDG uptake and its association with patient characteristics and blood chemistry
Variations in hepatic FDG uptake and its association with patient characteristics and blood chemistry Open
View article: Novel technique of detecting inflammatory and osseous changes in the glenohumeral joint associated with patient age and weight using FDG- and NaF-PET imaging.
Novel technique of detecting inflammatory and osseous changes in the glenohumeral joint associated with patient age and weight using FDG- and NaF-PET imaging. Open
Our study demonstrates the varying effect of limb laterality and BMI on FDG and NaF uptake at the GH joint. Adoption of molecular imaging will require future studies that correlate tracer uptake with relevant medical and illness history as…
View article: Role of 18F-FDG PET/CT to evaluate the effects of chimeric antigen receptor T-cell therapy on lymph node involvement in patients with non-Hodgkin lymphoma
Role of 18F-FDG PET/CT to evaluate the effects of chimeric antigen receptor T-cell therapy on lymph node involvement in patients with non-Hodgkin lymphoma Open