William St Clair
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View article: Feasibility of treatment planning with HyperArc stereotactic radiosurgery methods for ocular tumors
Feasibility of treatment planning with HyperArc stereotactic radiosurgery methods for ocular tumors Open
Purpose/objectives Currently, ocular disease is primarily managed with COMS plaque brachytherapy. Various stereotactic radiosurgery (SRS) platforms have also been employed, yet widespread access remains a challenge. Herein, we demonstrate …
View article: Demonstration of an enhanced dosing pattern for debulking large and bulky unresectable tumors via differential hole‐size spatially fractionated radiotherapy
Demonstration of an enhanced dosing pattern for debulking large and bulky unresectable tumors via differential hole‐size spatially fractionated radiotherapy Open
Purpose/objective We propose a novel lattice deployment for spatially fractionated radiotherapy (SFRT) treatments. In this approach, a larger diameter high‐dose sphere is centrally placed in the bulky tumor mass and surrounded by smaller d…
View article: An investigation into the feasibility and efficacy of stereotactic radiosurgery for 1–3 cm single brain lesions on the ring‐mounted Halcyon LINAC
An investigation into the feasibility and efficacy of stereotactic radiosurgery for 1–3 cm single brain lesions on the ring‐mounted Halcyon LINAC Open
Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐hou…
View article: A knowledge‐based planning model to identify fraction‐reduction opportunities in brain stereotactic radiotherapy
A knowledge‐based planning model to identify fraction‐reduction opportunities in brain stereotactic radiotherapy Open
Objective To develop and validate a HyperArc‐based RapidPlan (HARP) model for three‐fraction brain stereotactic radiotherapy (SRT) plans to then use to replan previously treated five‐fraction SRT plans. Demonstrating the possibility of red…
View article: In Vitro α/β Ratio Variations in Cervical Cancer, with Consequent Effects on Equivalent Dose in 2 Gy Fraction in High-Dose-Rate Brachytherapy
In Vitro α/β Ratio Variations in Cervical Cancer, with Consequent Effects on Equivalent Dose in 2 Gy Fraction in High-Dose-Rate Brachytherapy Open
There was large variation in in vitro α/β values which presented as a right-skewed log-normal distribution with a most probable value of ∼4.3 Gy for cervical cancer. Adenocarcinoma showed somewhat lower average α/β values compared with squ…
View article: Replacing 2 Gy Per Fraction Equivalent Dose with Fractionation-Specific Biological Equivalent Dose for Normal Tissues
Replacing 2 Gy Per Fraction Equivalent Dose with Fractionation-Specific Biological Equivalent Dose for Normal Tissues Open
The 2 Gy per fraction equivalent dose (EQD2) is an important quantity used in determining equivalent prescription doses for different fractionation regimens and evaluating different fractionation regimens, but it does not match its definit…
View article: Automated hippocampal sparing whole brain radiotherapy with simultaneous integrated boost for multiple brain metastases: Halcyon, HyperArc on TrueBeam, and coplanar TrueBeam
Automated hippocampal sparing whole brain radiotherapy with simultaneous integrated boost for multiple brain metastases: Halcyon, HyperArc on TrueBeam, and coplanar TrueBeam Open
Purpose To demonstrate the ease and feasibility that hippocampal sparing whole brain (WB) simultaneous integrated boost (HSWB‐SIB) plans can be generated using knowledge‐based planning and Eclipse Scripting Application Programming Interfac…
View article: Dosimetric impact of intrafraction patient motion on MLC‐based 3D‐conformal spatially fractionated radiation therapy treatment of large and bulky tumors
Dosimetric impact of intrafraction patient motion on MLC‐based 3D‐conformal spatially fractionated radiation therapy treatment of large and bulky tumors Open
Purpose To evaluate the dosimetric impact on spatially fractionated radiation therapy (SFRT) plan quality due to intrafraction patient motion via multi‐field MLC‐based method for treating large and bulky (≥8 cm) unresectable tumors. Method…
View article: 4. Poets and Travellers
4. Poets and Travellers Open
Chapter 4, ‘Poets and Travellers’ (1998), explores various aspects of Lord Byron’s literary and political engagements, beginning by focusing on his satirical work ‘English Bards and Scotch Reviewers.’ William St Clair details the poem’s tu…
View article: Stereotactic radiotherapy of intracranial tumor beds on a ring‐mounted Halcyon LINAC
Stereotactic radiotherapy of intracranial tumor beds on a ring‐mounted Halcyon LINAC Open
Purpose This study sought to evaluate the feasibility and efficacy of the Halcyon Ring Delivery System (RDS) for delivering stereotactic radiotherapy (SRT) treatments for intracranial tumors beds. Methods Ten previously treated brain SRT p…
View article: Weighted mean difference statistics for paired data in the presence of missing values
Weighted mean difference statistics for paired data in the presence of missing values Open
Missing data is a common issue in many biomedical studies. Under a paired design, some subjects may have missing values in either one or both of the conditions due to loss of follow-up, insufficient biological samples, etc. Such partially …
View article: 4. A New Answer to an Old Question
4. A New Answer to an Old Question Open
Complementing Who Saved the Parthenon? this companion volume sets aside more recent narratives surrounding the Athenian Acropolis, supposedly ‘the very symbol of democracy itself’, instead asking if we can truly access an ancient past impu…
View article: 5. ‘On the Temple dedicated to the Divine Minerva, vulgarly called the Parthenon’
5. ‘On the Temple dedicated to the Divine Minerva, vulgarly called the Parthenon’ Open
Complementing Who Saved the Parthenon? this companion volume sets aside more recent narratives surrounding the Athenian Acropolis, supposedly ‘the very symbol of democracy itself’, instead asking if we can truly access an ancient past impu…
View article: 3. Looking at the Parthenon in Classical Athens
3. Looking at the Parthenon in Classical Athens Open
Complementing Who Saved the Parthenon? this companion volume sets aside more recent narratives surrounding the Athenian Acropolis, supposedly ‘the very symbol of democracy itself’, instead asking if we can truly access an ancient past impu…
View article: The Classical Parthenon
The Classical Parthenon Open
Complementing Who Saved the Parthenon? this companion volume sets aside more recent narratives surrounding the Athenian Acropolis, supposedly ‘the very symbol of democracy itself’, instead asking if we can truly access an ancient past impu…
View article: Preface
Preface Open
Complementing Who Saved the Parthenon? this companion volume sets aside more recent narratives surrounding the Athenian Acropolis, supposedly ‘the very symbol of democracy itself’, instead asking if we can truly access an ancient past impu…
View article: 1. Recovering the Strangeness
1. Recovering the Strangeness Open
Complementing Who Saved the Parthenon? this companion volume sets aside more recent narratives surrounding the Athenian Acropolis, supposedly ‘the very symbol of democracy itself’, instead asking if we can truly access an ancient past impu…
View article: 2. ‘How do we set straight our sacred city?’
2. ‘How do we set straight our sacred city?’ Open
Complementing Who Saved the Parthenon? this companion volume sets aside more recent narratives surrounding the Athenian Acropolis, supposedly ‘the very symbol of democracy itself’, instead asking if we can truly access an ancient past impu…
View article: 6. Heritage
6. Heritage Open
Complementing Who Saved the Parthenon? this companion volume sets aside more recent narratives surrounding the Athenian Acropolis, supposedly ‘the very symbol of democracy itself’, instead asking if we can truly access an ancient past impu…
View article: Clinical validation of novel lightning dose optimizer for gamma knife radiosurgery of irregular‐shaped arteriovenous malformations and pituitary adenomas
Clinical validation of novel lightning dose optimizer for gamma knife radiosurgery of irregular‐shaped arteriovenous malformations and pituitary adenomas Open
Purpose To demonstrate the clinical feasibility of a novel treatment planning algorithm via lightning dose optimizer (LDO) on Leksell Gamma Knife (LGK) GammaPlan with significantly faster planning times for stereotactic radiosurgery (SRS) …
View article: The RelB-BLNK Axis Determines Cellular Response to a Novel Redox-Active Agent Betamethasone during Radiation Therapy in Prostate Cancer
The RelB-BLNK Axis Determines Cellular Response to a Novel Redox-Active Agent Betamethasone during Radiation Therapy in Prostate Cancer Open
Aberrant levels of reactive oxygen species (ROS) are potential mechanisms that contribute to both cancer therapy efficacy and the side effects of cancer treatment. Upregulation of the non-canonical redox-sensitive NF-kB family member, RelB…
View article: 23. Whose Parthenon?
23. Whose Parthenon? Open
In this magisterial book, William St Clair unfolds the history of the Parthenon throughout the modern era to the present day, with special emphasis on the period before, during, and after the Greek War of Independence of 1821–32.
View article: 4. The Encounter
4. The Encounter Open
In this magisterial book, William St Clair unfolds the history of the Parthenon throughout the modern era to the present day, with special emphasis on the period before, during, and after the Greek War of Independence of 1821–32.
View article: 19. The Silence
19. The Silence Open
In this magisterial book, William St Clair unfolds the history of the Parthenon throughout the modern era to the present day, with special emphasis on the period before, during, and after the Greek War of Independence of 1821–32.
View article: Who Saved the Parthenon?
Who Saved the Parthenon? Open
In this magisterial book, William St Clair unfolds the history of the Parthenon throughout the modern era to the present day, with special emphasis on the period before, during, and after the Greek War of Independence of 1821–32. Focusing …
View article: 24. The Parthenon in our Time
24. The Parthenon in our Time Open
In this magisterial book, William St Clair unfolds the history of the Parthenon throughout the modern era to the present day, with special emphasis on the period before, during, and after the Greek War of Independence of 1821–32.