Wilson W. K. Yip
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View article: Long-Term Evaluation of Ocular Surface and Meibomian Gland Function after Laser-Assisted in situ Keratomileusis Surgery
Long-Term Evaluation of Ocular Surface and Meibomian Gland Function after Laser-Assisted in situ Keratomileusis Surgery Open
Introduction: Laser-assisted in situ keratomileusis (LASIK) is a common refractive surgery. But it may lead to temporary dry eye due to reversible damage to the corneal subbasal nerve plexus. However, evidence on chronic ocular surface cha…
View article: Successful corneal endothelium preservation in the management of epithelial downgrowth with 5-fluorouracil injections and membranectomy
Successful corneal endothelium preservation in the management of epithelial downgrowth with 5-fluorouracil injections and membranectomy Open
A 74-year-old Chinese man underwent extracapsular cataract extraction in his right eye and developed a translucent iris membrane 4 months later. He was treated with two intracameral 5-FU injections and membranectomy at 2 weeks apart. At on…
View article: Successful Corneal Endothelium Preservation in the Management of Epithelial Downgrowth with 5-Fluorouracil injections and membranectomy
Successful Corneal Endothelium Preservation in the Management of Epithelial Downgrowth with 5-Fluorouracil injections and membranectomy Open
A 74-year-old Chinese man underwent extracapsular cataract extraction in his right eye and developed a translucent iris membrane 4 months later. He was treated with two intracameral 5-FU injections and membranectomy at 2 weeks apart. At on…
View article: Epidemiology of thyroid-stimulating immunoglobulin in recent-onset symptomatic thyroid eye disease
Epidemiology of thyroid-stimulating immunoglobulin in recent-onset symptomatic thyroid eye disease Open
Purpose This study aims to report correlations between thyroid-stimulating immunoglobulin (TSI) and both clinical and radiological parameters in recent-onset symptomatic thyroid eye disease (TED) patients. Methods A prospective cohort stud…
View article: Orbital radiotherapy with combined intravenous methylprednisolone and mycophenolate mofetil in moderate-to-severe thyroid eye disease
Orbital radiotherapy with combined intravenous methylprednisolone and mycophenolate mofetil in moderate-to-severe thyroid eye disease Open
To report the clinical outcomes of Orbital Radiotherapy (ORT) with combined Intravenous methylprednisolone (IVMP) and Mycophenolate mofetil (MMF) in Thyroid Eye Disease (TED) patients with restrictive myopathy. Prospective comparative case…
View article: Successful Corneal Endothelium Preservation in the Management of an Iris Membrane with repeated 5- Fluorouracil injections and membranectomy
Successful Corneal Endothelium Preservation in the Management of an Iris Membrane with repeated 5- Fluorouracil injections and membranectomy Open
A 74-year-old Chinese man underwent extracapsular cataract extraction in his right eye and developed a translucent iris membrane 4 months later. He was treated with two intracameral 5-FU injections and membranectomy at 2 weeks apart. At on…
View article: Cost-effectiveness of virtual reality and wet laboratory cataract surgery simulation
Cost-effectiveness of virtual reality and wet laboratory cataract surgery simulation Open
Purpose: To evaluate the cost-effectiveness of phacoemulsification simulation training in virtual reality simulator and wet laboratory on operating theater performance. Methods: Residents were randomized to a combination of virtual reality…
View article: Association of Polymorphisms in <i>ZFHX1B</i> and <i>PAX6</i> With Anisometropia in Chinese Children: The Hong Kong Children Eye Genetics Study
Association of Polymorphisms in <i>ZFHX1B</i> and <i>PAX6</i> With Anisometropia in Chinese Children: The Hong Kong Children Eye Genetics Study Open
This study identified two susceptible gene variants, ZFHX1B rs13382811 and PAX6 rs644242, for anisometropia development in Hong Kong Chinese children, implicating their role in imbalanced refractive change and axial elongation between both…
View article: Efficacy and Safety of 6-Weekly versus 12-Weekly Intravenous Methylprednisolone in Moderate-to-Severe Active Thyroid-Associated Ophthalmopathy
Efficacy and Safety of 6-Weekly versus 12-Weekly Intravenous Methylprednisolone in Moderate-to-Severe Active Thyroid-Associated Ophthalmopathy Open
Purpose: To compare the efficacy and safety of 6-weekly and 12-weekly intravenous methylprednisolone (IVMP) regimens in moderate-to-severe, active thyroid-associated orbitopathy (TAO) patients. Basic Procedures: Retrospective comparative s…
View article: Effect of Low-Concentration Atropine Eyedrops vs Placebo on Myopia Incidence in Children
Effect of Low-Concentration Atropine Eyedrops vs Placebo on Myopia Incidence in Children Open
Importance Early onset of myopia is associated with high myopia later in life, and myopia is irreversible once developed. Objective To evaluate the efficacy of low-concentration atropine eyedrops at 0.05% and 0.01% concentration for delayi…
View article: Radiological Determinants of Complicated Immunoglobulin G4–Related Ophthalmic Disease: A Territory-Wide Cohort Study
Radiological Determinants of Complicated Immunoglobulin G4–Related Ophthalmic Disease: A Territory-Wide Cohort Study Open
In this IgG4-ROD cohort, most patients had bilateral enlarged lacrimal glands, and the lateral rectus is the most frequently involved EOM. For the first time, unique radiological patterns associated with the development of IgG4-RON and IgG…
View article: Three-Dimensional Multi-Task Deep Learning Model to Detect Glaucomatous Optic Neuropathy and Myopic Features From Optical Coherence Tomography Scans: A Retrospective Multi-Centre Study
Three-Dimensional Multi-Task Deep Learning Model to Detect Glaucomatous Optic Neuropathy and Myopic Features From Optical Coherence Tomography Scans: A Retrospective Multi-Centre Study Open
Purpose We aim to develop a multi-task three-dimensional (3D) deep learning (DL) model to detect glaucomatous optic neuropathy (GON) and myopic features (MF) simultaneously from spectral-domain optical coherence tomography (SDOCT) volumetr…
View article: Malignancies in Immunoglobulin G4-Related Ophthalmic Disease
Malignancies in Immunoglobulin G4-Related Ophthalmic Disease Open
Purpose: Clinical phenotypes in Immunoglobulin G4-related disease (IgG4-RD) according to the affected organs affected have different risks of malignancies. We attempt to determine the association of malignances with IgG4-related ophthalmic…
View article: A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis
A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis Open
Objective: Diabetic macular edema (DME) is the primary cause of vision loss among individuals with diabetes mellitus (DM). We developed, validated, and tested a deep-learning (DL) system for classifying DME using images from three common c…
View article: A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis
A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis Open
Objective: Diabetic macular edema (DME) is the primary cause of vision loss among individuals with diabetes mellitus (DM). We developed, validated, and tested a deep-learning (DL) system for classifying DME using images from three common c…
View article: A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis
A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis Open
OBJECTIVE Diabetic macular edema (DME) is the primary cause of vision loss among individuals with diabetes mellitus (DM). We developed, validated, and tested a deep learning (DL) system for classifying DME using images from three common co…
View article: Prevalence of strabismus and its risk factors among school aged children: The Hong Kong Children Eye Study
Prevalence of strabismus and its risk factors among school aged children: The Hong Kong Children Eye Study Open
The study aims to determine the prevalence of strabismus and its risk factors among school children in Hong Kong. This is a cross-sectional study involving 6–8 year old children from different districts in Hong Kong. 4273 children received…
View article: Paediatric glaucoma in Hong Kong: a multicentre retrospective analysis of epidemiology, presentation, clinical interventions, and outcomes
Paediatric glaucoma in Hong Kong: a multicentre retrospective analysis of epidemiology, presentation, clinical interventions, and outcomes Open
Primary congenital glaucoma was most prevalent, followed by juvenile open-angle glaucoma and aphakic glaucoma. Most eyes with primary glaucoma required surgical treatment. Parental concerns were important clinical presentations. Basic asse…
View article: A Six-Year Review of the Latest Oculoplastic Surgical Development
A Six-Year Review of the Latest Oculoplastic Surgical Development Open
The recent trend of periocular surgical rejuvenation focuses on preserving soft tissue volume, avoiding skin or use hidden incision, taking the eyebrow and midface position into account, and measures to minimize iatrogenic eyelid malpositi…
View article: Association of<i>WNT7B</i>and<i>RSPO1</i>with Axial Length in School Children
Association of<i>WNT7B</i>and<i>RSPO1</i>with Axial Length in School Children Open
This study revealed that the RSPO1 SNP rs12144790 was associated with AL, whereas WNT7B rs10453441 was associated with AL, CC, and CCT in children. A novel association between ZNRF3 rs12321 and CC was discovered. Our data suggest that the …