Wireko Andrew Awuah
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View article: Chiari Malformation I and abducens nerve palsy: an overview of the documented cases
Chiari Malformation I and abducens nerve palsy: an overview of the documented cases Open
Introduction Chiari malformation (CM) type I is commonly distinguished by the caudal displacement of the cerebellar tonsils via the foramen magnum, leading to the compression of the brainstem and spinal cord. Lower cranial nerve palsies ar…
View article: The Artery of Desproges-Gotteron: Anatomical, Pathological and Neurosurgical Significance
The Artery of Desproges-Gotteron: Anatomical, Pathological and Neurosurgical Significance Open
Background: In 1955, the pioneering work of Robert Desproges-Gotteron greatly improved our understanding of the anatomy of the human vasculature, in particular the discovery of the Artery of Desproges-Gotteron (ADG). The aim of this study …
View article: Voclosporin: A comprehensive review of its role as a novel calcineurin inhibitor in the management of systemic lupus erythematosus
Voclosporin: A comprehensive review of its role as a novel calcineurin inhibitor in the management of systemic lupus erythematosus Open
Systemic lupus erythematosus is an autoimmune disease with diverse clinical manifestations, including lupus nephritis. Calcineurin inhibitors (CNIs) are a treatment option, but traditional CNIs have limitations. Voclosporin, a novel oral C…
View article: 646 Exploring the Future of Transcatheter Tricuspid Valve Replacement: Short-, Mid-, and Long-Term Outcomes and Complications Across Innovative Valve Systems
646 Exploring the Future of Transcatheter Tricuspid Valve Replacement: Short-, Mid-, and Long-Term Outcomes and Complications Across Innovative Valve Systems Open
Aim This study compares the clinical outcomes and complications of three transcatheter tricuspid valve replacement (TTVR) systems—EVOQUE, LuX valve, and NaviGate—focusing on short-, mid-, and long-term results. Method A comprehensive liter…
View article: 792 Communication and Collaboration Between Anaesthetists and Surgeons: A Systematic Review and Dynamic Network Analysis of Intraoperative Team Dynamics
792 Communication and Collaboration Between Anaesthetists and Surgeons: A Systematic Review and Dynamic Network Analysis of Intraoperative Team Dynamics Open
Aim This study aims to comprehensively assess the impact of communication and collaboration between anaesthetists and surgeons on intraoperative team dynamics and patient safety. By combining a systematic review with dynamic network analys…
View article: Microgravity-induced alterations in the molecular and cellular characteristics of brain tumors: a systematic review
Microgravity-induced alterations in the molecular and cellular characteristics of brain tumors: a systematic review Open
Background: Microgravity profoundly impacts various biological functions, including those crucial to tumorigenesis. Investigating the effects of microgravity on brain tumors is pivotal for understanding tumor biology and developing novel t…
View article: Cardio-oncology care in Africa: current trends and disparities
Cardio-oncology care in Africa: current trends and disparities Open
The emerging discipline of cardio-oncology addresses the cardiovascular complications associated with cancer therapies. In sub-Saharan Africa (SSA), where both cardiovascular disease (CVD) and cancer-related mortality are increasing, the d…
View article: Recent advances in 3D printing applications for CNS tumours
Recent advances in 3D printing applications for CNS tumours Open
Three-dimensional printing (3DP) has emerged as a transformative technology in the field of central nervous system (CNS) tumours, offering innovative advancements in various aspects of diagnosis, treatment and education. By precisely repli…
View article: Pericallosal artery aneurysms: an evidence-based analysis of clinical presentations, therapeutic approaches, and outcome
Pericallosal artery aneurysms: an evidence-based analysis of clinical presentations, therapeutic approaches, and outcome Open
View article: Retention of HIV clients in care: A comparative study to highlight the benefit of HIV clinical mentorship program in Nasarawa State, Nigeria
Retention of HIV clients in care: A comparative study to highlight the benefit of HIV clinical mentorship program in Nasarawa State, Nigeria Open
Background: Retention in care is a critical indicator of the quality of HIV care and a cornerstone for achieving epidemic control. Interruption in treatment (IIT) poses a significant threat to achieving the global 95-95-95 targets and lead…
View article: A comprehensive review of the clinical presentation, diagnosis, and treatment of calcineurin inhibitor-induced pain syndrome
A comprehensive review of the clinical presentation, diagnosis, and treatment of calcineurin inhibitor-induced pain syndrome Open
View article: The role of advocacy and policy in advancing global neurosurgery
The role of advocacy and policy in advancing global neurosurgery Open
Global neurosurgery has witnessed transformative developments in advocacy and policy aimed at overcoming the barriers that hinder equitable access to neurosurgical care. This paper reveals the stark disparities faced by low- and middle-inc…
View article: Predicting survival in malignant glioma using artificial intelligence
Predicting survival in malignant glioma using artificial intelligence Open
Malignant gliomas, including glioblastoma, are amongst the most aggressive primary brain tumours, characterised by rapid progression and a poor prognosis. Survival analysis is an essential aspect of glioma management and research, as most …
View article: Improving diagnostics and surveillance of malaria among displaced people in Africa
Improving diagnostics and surveillance of malaria among displaced people in Africa Open
View article: The 100 most-cited papers on esthesioneuroblastoma: a bibliometric analysis
The 100 most-cited papers on esthesioneuroblastoma: a bibliometric analysis Open
Objective: Esthesioneuroblastoma (ENB) or olfactory neuroblastoma, an infrequent neuroectodermal tumor primarily affecting the nasal cavity, manifests sporadically or in various clinical contexts. Bibliometric analyses have become a techni…
View article: The Clinical Presentation, Treatment Modalities, and Outcomes Associated with Interhemispheric Subdural Hematomas
The Clinical Presentation, Treatment Modalities, and Outcomes Associated with Interhemispheric Subdural Hematomas Open
Interhemispheric subdural hematoma (ISH) poses significant challenges in neurosurgical practice owing to its deep localization within the cerebral hemispheres. Despite widespread adoption of advanced neurosurgical technologies, adverse pat…
View article: Current status of neurotrauma management in resource-limited settings
Current status of neurotrauma management in resource-limited settings Open
Over the last several decades neurotrauma has become recognized as a significant contributor to poor health outcomes, with growing physical, cognitive, social, and economic burdens. Although it serves as a significant contributor globally,…
View article: Advances in chromosomal microarray analysis: Transforming neurology and neurosurgery
Advances in chromosomal microarray analysis: Transforming neurology and neurosurgery Open
View article: The transformative power of telemedicine in delivering effective neurosurgical care in low and middle-income countries: A review
The transformative power of telemedicine in delivering effective neurosurgical care in low and middle-income countries: A review Open
View article: Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications
Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications Open
View article: Exploring the current provision of pancreatic transplantations in low- and middle-income countries: Current landscape, challenges, future prospects
Exploring the current provision of pancreatic transplantations in low- and middle-income countries: Current landscape, challenges, future prospects Open
This comprehensive review addresses the global health challenge of disparities in pancreas transplant access, particularly in low- and middle-income countries (LMICs) compared to high-income countries. Despite advancements in surgical tech…
View article: Genes to therapy: a comprehensive literature review of whole-exome sequencing in neurology and neurosurgery
Genes to therapy: a comprehensive literature review of whole-exome sequencing in neurology and neurosurgery Open
View article: Dandy–Walker syndrome: a bibliometric analysis of the most 100 cited articles
Dandy–Walker syndrome: a bibliometric analysis of the most 100 cited articles Open
Introduction: Dandy–Walker syndrome (DWS), a complex neurodevelopmental disorder, has intrigued clinicians and researchers since its description by physicians Walter Dandy and Arthur Walker. Despite its recognition for nearly a century, un…
View article: Soft Tissue Sarcoma in Sub‐Saharan Africa: Surgical Management Outcomes, Gaps, and Future Prospects: A Narrative Review
Soft Tissue Sarcoma in Sub‐Saharan Africa: Surgical Management Outcomes, Gaps, and Future Prospects: A Narrative Review Open
Background and Aims The diagnosis and management of soft tissue sarcoma (STS) in sub‐Saharan Africa (SSA) present significant challenges. Positive outcomes in STS treatment include achieving negative margins, improved quality of life, and …
View article: Pericallosal Artery Aneurysms: An Evidence-Based Analysis of Clinical Presentations, Therapeutic Approaches, and Outcome
Pericallosal Artery Aneurysms: An Evidence-Based Analysis of Clinical Presentations, Therapeutic Approaches, and Outcome Open
Background: Pericallosal artery aneurysms (PCAA) are relatively rare intracranial aneurysms that present unique challenges in diagnosis and management. This study provides a comprehensive review of the literature to assess demographic patt…
View article: Beyond the operating room: addressing the “second-victim” phenomenon in surgical practice
Beyond the operating room: addressing the “second-victim” phenomenon in surgical practice Open
Complications are plausible events during surgical operations. Surgical complications profoundly impact surgeons, often called "second victims" of adverse events. These complications trigger a range of emotional and psychological responses…
View article: Addressing abdominal trauma from conflict and warfare in under‐resourced regions: A critical narrative review
Addressing abdominal trauma from conflict and warfare in under‐resourced regions: A critical narrative review Open
Introduction The prevalence of abdominal injuries in war and conflict zones, particularly in low‐ and middle‐income countries (LMICs), presents a significant healthcare challenge. These injuries, often resulting from explosive devices, fir…
View article: Exoscope-assisted spine surgery: Current applications and future directions–A short review
Exoscope-assisted spine surgery: Current applications and future directions–A short review Open
Spine surgery is a critical field that seeks to alleviate pain and restore function in patients with various spinal pathologies. Over the years, spine surgery has seen advancements such as minimally invasive techniques with operative micro…
View article: Cancer stem cells in meningiomas: novel insights and therapeutic implications
Cancer stem cells in meningiomas: novel insights and therapeutic implications Open
Meningiomas (MGs), which arise from meningothelial cells of the dura mater, represent a significant proportion of primary tumours of the central nervous system (CNS). Despite advances in treatment, the management of malignant meningioma (M…
View article: Novel insights into the role of TREM2 in cerebrovascular diseases
Novel insights into the role of TREM2 in cerebrovascular diseases Open
Cerebrovascular diseases (CVDs) include conditions such as stroke, cerebral amyloid angiopathy (CAA) and cerebral small vessel disease (CSVD), which contribute significantly to global morbidity and healthcare burden. The pathophysiology of…