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View article: Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi <i>Malassezia furfur</i>
Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi <i>Malassezia furfur</i> Open
Malassezia is the dominant genus of fungi residing on human skin and is associated with both healthy skin and many dermatological conditions. Among these skin diseases, pityriasis versicolor (PV) has strong etiological connections with Mal…
View article: Non-synonymous ERG11 mutations in <i>M. restricta</i> and <i>M. arunalokei</i> : impact on azole susceptibility
Non-synonymous ERG11 mutations in <i>M. restricta</i> and <i>M. arunalokei</i> : impact on azole susceptibility Open
Malassezia are commensal lipid-dependent yeasts and opportunistic pathogens that cause superficial mycoses and systemic infection. Azole antifungals target cell wall ergosterol synthesis and are the first line of antifungal treatment. ERG1…
View article: Detection of Bacterial Neutral Ceramidase in Diabetic Foot Ulcers with an Optimized Substrate and Chemoenzymatic Probes
Detection of Bacterial Neutral Ceramidase in Diabetic Foot Ulcers with an Optimized Substrate and Chemoenzymatic Probes Open
Ceramidases (CDases) are important in controlling skin barrier integrity by regulating ceramide composition and affording downstream signal molecules. While the functions of epidermal CDases are known, roles of neutral CDases secreted by s…
View article: A wireless and battery-free wound infection sensor based on DNA hydrogel
A wireless and battery-free wound infection sensor based on DNA hydrogel Open
A wireless sensor based on bioresponsive DNA hydrogel provides smartphone-based detection of wound infection.
View article: Secretory Proteases of the Human Skin Microbiome
Secretory Proteases of the Human Skin Microbiome Open
The human skin is our outermost layer and serves as a protective barrier against external insults. Advances in next-generation sequencing have enabled the discoveries of a rich and diverse community of microbes—bacteria, fungi, and viruses…
View article: Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation
Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation Open
Malassezia is the most abundant eukaryotic microbial genus on human skin. Similar to many human-residing fungi, Malassezia has high metabolic potential and secretes a plethora of hydrolytic enzymes that can potentially modify and structure…