Wissam Farhat
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View article: Development and Characterization of a Photocrosslinkable, Chitosan-Based, Nerve Growth Factor–Eluting Hydrogel for the Ocular Surface
Development and Characterization of a Photocrosslinkable, Chitosan-Based, Nerve Growth Factor–Eluting Hydrogel for the Ocular Surface Open
Az-Ch hydrogels may be used to enhance rhNGF therapy in patients with NK.
View article: Topical Sustained Delivery of Miltefosine Via Drug-Eluting Contact Lenses to Treat Acanthamoeba Keratitis
Topical Sustained Delivery of Miltefosine Via Drug-Eluting Contact Lenses to Treat Acanthamoeba Keratitis Open
This study aimed to develop a miltefosine-eluting contact lens (MLF-CL) device that would allow sustained and localized miltefosine release for the treatment of Acanthamoeba keratitis. MLF-CLs were produced in three different miltefosine d…
View article: Doxorubicin-Loaded Extracellular Vesicles Enhance Tumor Cell Death in Retinoblastoma
Doxorubicin-Loaded Extracellular Vesicles Enhance Tumor Cell Death in Retinoblastoma Open
Chemotherapy is often used to treat retinoblastoma; however, this treatment method has severe systemic adverse effects and inadequate therapeutic effectiveness. Extracellular vesicles (EVs) are important biological information carriers tha…
View article: Extracellular Vesicles in Corneal Fibrosis/Scarring
Extracellular Vesicles in Corneal Fibrosis/Scarring Open
Communication between cells and the microenvironment is a complex, yet crucial, element in the development and progression of varied physiological and pathological processes. Accumulating evidence in different disease models highlights rol…
View article: Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography
Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography Open
Cholangiocytes, biliary epithelial cells, are known to spontaneously self-organize into spherical cysts with a central lumen. In this work, we explore a promising biocompatible stereolithographic approach to encapsulate cholangiocytes into…
View article: Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography
Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography Open
Cholangiocytes, biliary epithelial cells, are known to spontaneously self-organize into spherical cysts with a central lumen. In this work, we explore a promising biocompatible stereolithographic approach to encapsulate cholangiocytes into…
View article: Trends in 3D bioprinting for esophageal tissue repair and reconstruction
Trends in 3D bioprinting for esophageal tissue repair and reconstruction Open
In esophageal pathologies, such as esophageal atresia, cancers, caustic burns, or post-operative stenosis, esophageal replacement is performed by using parts of the gastrointestinal tract to restore nutritional autonomy. However, this surg…
View article: Lactone monomers obtained by enzyme catalysis and their use in reversible thermoresponsive networks
Lactone monomers obtained by enzyme catalysis and their use in reversible thermoresponsive networks Open
Enzyme‐catalyzed transformations have a great potential in both the pharmaceutical and chemical industry to achieve complex and (stereo)selective synthesis under mild reaction conditions. Still, the implementation of biocatalysis in the pr…
View article: Biocatalysis for terpene-based polymers
Biocatalysis for terpene-based polymers Open
Accelerated generation of bio-based materials is vital to replace current synthetic polymers obtained from petroleum with more sustainable options. However, many building blocks available from renewable resources mainly contain unreactive …
View article: Investigation of hemicellulose biomaterial approaches : the extraction and modification of hemicellulose and its use in value-added applications
Investigation of hemicellulose biomaterial approaches : the extraction and modification of hemicellulose and its use in value-added applications Open
The increased use of renewable materials is considered as one of the key issue of the sustainable development. Carbohydrates are readily biodegradable and tend to degrade in biologically active environments. Hemicelluloses (HC) are one of …
View article: Cigarette Smoking-Induced Cardiac Hypertrophy, Vascular Inflammation and Injury Are Attenuated by Antioxidant Supplementation in an Animal Model
Cigarette Smoking-Induced Cardiac Hypertrophy, Vascular Inflammation and Injury Are Attenuated by Antioxidant Supplementation in an Animal Model Open
Background: Cardiovascular diseases are the leading causes of morbidity and mortality worldwide. Cigarette smoking remains a global health epidemic with associated detrimental effects on the cardiovascular system. In this work, we investig…