Richard Lee
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View article: International consensuses and guidelines on managing ocular Behçet’s disease by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-Retina Society (APVRS), the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII) and the Academia Retina Internationalis (ARI)
International consensuses and guidelines on managing ocular Behçet’s disease by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-Retina Society (APVRS), the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII) and the Academia Retina Internationalis (ARI) Open
Behçet's disease remains a complex and challenging form of uveitis, marked by a high rate of relapse, significant inflammation, and a long-term risk of visual acuity loss. The introduction of biologics, especially anti-tumour necrosis fact…
View article: MedSR-Impact: Transformer-Based Super-Resolution for Lung CT Segmentation, Radiomics, Classification, and Prognosis
MedSR-Impact: Transformer-Based Super-Resolution for Lung CT Segmentation, Radiomics, Classification, and Prognosis Open
High-resolution volumetric computed tomography (CT) is essential for accurate diagnosis and treatment planning in thoracic diseases; however, it is limited by radiation dose and hardware costs. We present the Transformer Volumetric Super-R…
View article: Prenatal exposure to extreme ambient heat may amplify the adverse impact of Superstorm Sandy on basal ganglia volume among school-aged children
Prenatal exposure to extreme ambient heat may amplify the adverse impact of Superstorm Sandy on basal ganglia volume among school-aged children Open
Background Weather-related stressors on healthy brain development has become an important topic in recent years. Notably, prenatal stress exposure to natural disasters may disrupt child neurodevelopment, with recent research exploring its …
View article: Validated machine learning tools to distinguish immune checkpoint inhibitor, radiotherapy, COVID-19 and other infective pneumonitis
Validated machine learning tools to distinguish immune checkpoint inhibitor, radiotherapy, COVID-19 and other infective pneumonitis Open
Our results demonstrate the potential utility of such tools as a second or concurrent reader to support oncologists, radiologists, and chest physicians in cases of diagnostic uncertainty. Further research is required for patients with expo…
View article: Determining the impact of an artificial intelligence tool on the management of pulmonary nodules detected incidentally on CT (DOLCE) study protocol: a prospective, non-interventional multicentre UK study
Determining the impact of an artificial intelligence tool on the management of pulmonary nodules detected incidentally on CT (DOLCE) study protocol: a prospective, non-interventional multicentre UK study Open
Introduction In a small percentage of patients, pulmonary nodules found on CT scans are early lung cancers. Lung cancer detected at an early stage has a much better prognosis. The British Thoracic Society guideline on managing pulmonary no…
View article: Transcatheter endomyocardial alginate-hydrogel injection for treatment of heart failure
Transcatheter endomyocardial alginate-hydrogel injection for treatment of heart failure Open
Background and Aim Intramyocardial injection of alginate-hydrogel, an emerging and promising strategy for patients with advanced heart failure (HF), is limited by the paucity of commercially available intramyocardial delivery methods. This…
View article: Systemic immunosuppression depletes peripheral blood regulatory B cells in patients with immune thrombocytopenia
Systemic immunosuppression depletes peripheral blood regulatory B cells in patients with immune thrombocytopenia Open
Summary Regulatory B (Breg) cells are potentially implicated in the pathogenesis of immune thrombocytopenia (ITP). We analysed a prospective cohort of newly diagnosed steroid naïve ITP patients enrolled in the multicentre FLIGHT trial and …
View article: Evaluating the consistency between OCO-2 and OCO-3 XCO <sub>2</sub> estimates derived from the NASA ACOS version 10 retrieval algorithm
Evaluating the consistency between OCO-2 and OCO-3 XCO <sub>2</sub> estimates derived from the NASA ACOS version 10 retrieval algorithm Open
The version 10 (v10) Atmospheric Carbon Observations from Space (ACOS) Level 2 full-physics (L2FP) retrieval algorithm has been applied to multiyear records of observations from NASA's Orbiting Carbon Observatory 2 and 3 sensors (OCO-2 and…
View article: Kawasaki Disease in Children
Kawasaki Disease in Children Open
Kawasaki Disease (KD), previously defined as mucocutaneous lymph node syndrome, is a febrile illness caused by inflammation of the body's medium-sized blood vessels. Tomisaku Kawasaki first described it in 1967 as a self-limited acute vasc…
View article: The lung cancers: staging and response, CT, <sup>18</sup>F-FDG PET/CT, MRI, DWI: review and new perspectives
The lung cancers: staging and response, CT, <sup>18</sup>F-FDG PET/CT, MRI, DWI: review and new perspectives Open
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in both sexes combined. Recent years have seen major advances in the diagnostic and treatment options for patients with non-small-cell lung cancer (NS…
View article: Supplementary Table 2 from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Supplementary Table 2 from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment Open
Supplementary table 2
View article: Supplementary Figures from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Supplementary Figures from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment Open
Supplementary Figures
View article: Supplementary Information from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Supplementary Information from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment Open
1-Supplementary methods 2-Supplementary Figure legends 3-Supplementary references
View article: Supplementary Table 2 from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Supplementary Table 2 from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment Open
Supplementary table 2
View article: Supplementary Table 3 from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Supplementary Table 3 from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment Open
Supplementary table 3
View article: Data from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Data from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment Open
Lipid metabolism rearrangements in nonalcoholic fatty liver disease (NAFLD) contribute to disease progression. NAFLD has emerged as a major risk for hepatocellular carcinoma (HCC), where metabolic reprogramming is a hallmark. Identificatio…
View article: Supplementary Data from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Supplementary Data from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment Open
Full unedited blots
View article: Supplementary Data from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Supplementary Data from E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment Open
Full unedited blots
View article: Factors Predicting Long-term Outcome and the Need for Surgery in Graves Orbitopathy: Extended Follow-up From the CIRTED Trial
Factors Predicting Long-term Outcome and the Need for Surgery in Graves Orbitopathy: Extended Follow-up From the CIRTED Trial Open
Graves orbitopathy is both disabling and disfiguring. Medical therapies to reduce inflammation are widely used, but there is limited trial data beyond 18 months of follow-up. Methods Three-year follow-up of a subset of the CIRTED trial (N …