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View article: TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice
TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice Open
Acute systemic inflammation critically alters the function of the immune system, often promoting myelopoiesis at the expense of lymphopoiesis. In the thymus, systemic inflammation results in acute thymic atrophy and, consequently, impaired…
View article: Type 1 immunity enables neonatal thymic ILC1 production
Type 1 immunity enables neonatal thymic ILC1 production Open
Acute thymic atrophy occurs following type 1 inflammatory conditions such as viral infection and sepsis, resulting in cell death and disruption of T cell development. However, the impact type 1 immunity has on thymic-resident innate lympho…
View article: Type 1 immunity enables neonatal thymic ILC1 production
Type 1 immunity enables neonatal thymic ILC1 production Open
Thymic atrophy occurs following type 1 inflammatory conditions like viral infection and sepsis, resulting in cell death and disruption of T-cell development. However, it remains undetermined whether the thymus actively contributes to the i…