Kyungwon Lee
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View article: Prevalence and Molecular Epidemiology of Extended-Spectrum β-Lactamase–Producing <i>Escherichia coli</i> and Effects of Antimicrobial Use in Multiple Pig Industry Sectors in Korea
Prevalence and Molecular Epidemiology of Extended-Spectrum β-Lactamase–Producing <i>Escherichia coli</i> and Effects of Antimicrobial Use in Multiple Pig Industry Sectors in Korea Open
The findings highlight the significance of elucidating AMR networks among humans, animals, and the environment. Prudent antimicrobial usage and continuous AMR monitoring in the pig industry are crucial to safeguard food safety.
View article: Increasing Antimicrobial Resistance Profile Diversity of Colonizing Group B <i>Streptococcus</i> in Reproductive-aged Women in Korea
Increasing Antimicrobial Resistance Profile Diversity of Colonizing Group B <i>Streptococcus</i> in Reproductive-aged Women in Korea Open
The acquisition of diverse resistance genes has expanded AMR profiles in colonized GBS, emphasizing the need for sustained nationwide surveillance.
View article: Incidental Findings on Abdominopelvic CT in Young Korean Soldiers: Prevalence, Clinical Relevance, and Healthcare System Implications
Incidental Findings on Abdominopelvic CT in Young Korean Soldiers: Prevalence, Clinical Relevance, and Healthcare System Implications Open
Background: This retrospective case series examines incidental findings (IFs) detected on abdominopelvic CT (APCT) among young Korean soldiers presenting with acute abdominal pain. APCT is a frontline test for acute abdominal pain but freq…
View article: Characterization of Antimicrobial Resistance and Hypervirulent Traits of Klebsiella variicola Isolates Collected in South Korea
Characterization of Antimicrobial Resistance and Hypervirulent Traits of Klebsiella variicola Isolates Collected in South Korea Open
Introduction: Klebsiella variicola, a member of Klebsiella pneumoniae complex, has emerged as an opportunistic pathogen for human infection; however, antimicrobial resistance and hypervirulent characteristics of K. variicola have rarely be…
View article: Harnessing Induced Pluripotent Stem Cells for Cardiac-Related Pain: Advances, Models, and Therapeutic Prospects
Harnessing Induced Pluripotent Stem Cells for Cardiac-Related Pain: Advances, Models, and Therapeutic Prospects Open
Cardiac pain is difficult to diagnose and treat in part because existing models fail to capture human neuro-cardiac signaling. This review examines how iPSC-derived cardiomyocytes and sensory neurons in co-culture and organoid systems mode…
View article: Incidental Findings on Abdominopelvic CT in Young Korean Soldiers: Prevalence, Clinical Relevance, and Healthcare System Implications
Incidental Findings on Abdominopelvic CT in Young Korean Soldiers: Prevalence, Clinical Relevance, and Healthcare System Implications Open
Background Abdominopelvic computed tomography (APCT) is a frontline diagnostic modality for acute abdominal pain, but it often reveals incidental findings (IFs) that are unrelated to the presenting complaint. While many IFs are benign, som…
View article: <i>In-vitro</i> Activities of Zoliflodacin and Solithromycin Against <i>Neisseria gonorrhoeae</i> Isolates from Korea
<i>In-vitro</i> Activities of Zoliflodacin and Solithromycin Against <i>Neisseria gonorrhoeae</i> Isolates from Korea Open
Novel antimicrobial agents are continually developed to address the global threat of multidrug-resistant Neisseria gonorrhoeae. Promising candidates include zoliflodacin and, possibly, solithromycin. We evaluated their in-vitro activities …
View article: Acceleration of Modeling Capability for GDI Spray by Machine-Learning Algorithms
Acceleration of Modeling Capability for GDI Spray by Machine-Learning Algorithms Open
Cold start causes a high amount of unburned hydrocarbon and particulate matter emissions in gasoline direct injection (GDI) engines. Therefore, it is necessary to understand the dynamics of spray during a cold start and develop a predictiv…
View article: Biochemical, structural, and single-molecule characterization of LIG1 active site mutants demonstrate role of F635 and F872 residues for faithful ligation
Biochemical, structural, and single-molecule characterization of LIG1 active site mutants demonstrate role of F635 and F872 residues for faithful ligation Open
Human DNA ligase 1 (LIG1) finalizes DNA repair pathways by an ultimate ligation step and discriminates against nicks containing unusual ends, yet the contribution of the conserved active site residues for faithful end joining remains unkno…
View article: Biosensor for integrin inhibition of mammalian cell adhesion and migration using micropatterned cell culture substrate and retroreflective optical signaling
Biosensor for integrin inhibition of mammalian cell adhesion and migration using micropatterned cell culture substrate and retroreflective optical signaling Open
Integrins are a family of transmembrane receptors that play a crucial role in cell adhesion and migration. Integrins can uniquely transduce biochemical signals bidirectionally across the membrane and physically link the cell-cell and cell-…
View article: Preclinical evaluation of NG101, a potential AAV gene therapy for wet age-related macular degeneration
Preclinical evaluation of NG101, a potential AAV gene therapy for wet age-related macular degeneration Open
Age-related macular degeneration (AMD) is a leading cause of vision loss in individuals over the age of 55. Approximately 10%-15% of AMD patients develop choroidal neovascularization (CNV), leading to wet AMD (wAMD), which accounts for nea…
View article: Clinically Probable Multiple System Atrophy Presenting Ptosis as an Early Manifestation
Clinically Probable Multiple System Atrophy Presenting Ptosis as an Early Manifestation Open
Many ocular features were found in patients with multiple system atrophy (MSA), which include dry eye, blepharospasm, eye movement problems, and blink reflex dysfunction. Some of these symptoms are associated with autonomic dysfunctions se…
View article: Clinical Outcomes and Molecular Characteristics of <i>Bacteroides fragilis</i> Infections
Clinical Outcomes and Molecular Characteristics of <i>Bacteroides fragilis</i> Infections Open
Bacteroides fragilis is the most common opportunistic anaerobic pathogen. In the absence of appropriate antimicrobial therapy, mortality rates associated with B. fragilis group infections can reach as high as 50%. Therefore, we aimed to el…
View article: Mutagenic ligation of polβ mismatch insertion products during 8-oxoG bypass by LIG1 and LIG3α at the downstream steps of base excision repair pathway
Mutagenic ligation of polβ mismatch insertion products during 8-oxoG bypass by LIG1 and LIG3α at the downstream steps of base excision repair pathway Open
Base excision repair (BER) maintains genome integrity by fixing oxidized bases that could be formed when reactive oxygen species attack directly on the DNA. We previously reported the importance of a proper coordination at the downstream s…
View article: Evaluation of the Disk Diffusion Test for <i>Bacteroides fragilis</i> Group Clinical Isolates
Evaluation of the Disk Diffusion Test for <i>Bacteroides fragilis</i> Group Clinical Isolates Open
The DDT can be a useful alternative antimicrobial susceptibility test for BFG isolates when using the ATU zone to reduce errors.
View article: <i>Pasteurella</i> Infections in South Korea and Systematic Review and Meta-analysis of <i>Pasteurella</i> Bacteremia
<i>Pasteurella</i> Infections in South Korea and Systematic Review and Meta-analysis of <i>Pasteurella</i> Bacteremia Open
Pasteurella spp. can cause fatal zoonotic infections in humans. We performed a multicenter study to investigate the prevalence and clinical features of Pasteurella infections in South Korea during 2018‒2022. We also conducted a collaborati…
View article: Reversible Lesion in the Splenium of the Corpus Callosum due to Thermogenic Dietary Supplements
Reversible Lesion in the Splenium of the Corpus Callosum due to Thermogenic Dietary Supplements Open
The use of thermogenic dietary supplements has led to growing concerns about potential adverse health effects. A 19-year-old female patient experienced recurrent blurred vision after consuming thermogenic dietary supplements for 5 weeks an…
View article: Prevalence and Molecular Characterization of Pharyngeal Gonorrhea in Korean Men With Urethritis
Prevalence and Molecular Characterization of Pharyngeal Gonorrhea in Korean Men With Urethritis Open
The prevalence of pharyngeal gonorrhea in Korean men with gonococcal urethritis is as high as 30.5%, highlighting the need for pharyngeal screening in high-risk groups. Ceftriaxone is the recommended treatment for pharyngeal gonorrhea.
View article: Anisotropic regularization for sparsely sampled and noise-robust Fourier ptychography
Anisotropic regularization for sparsely sampled and noise-robust Fourier ptychography Open
Fourier ptychography (FP) is a powerful computational imaging technique that provides super-resolution and quantitative phase imaging capabilities by scanning samples in Fourier space with angle-varying illuminations. However, the image re…
View article: 40‐2: A Novel Gamma Prediction Algorithm for AMOLED Display Based on Residual Network Model
40‐2: A Novel Gamma Prediction Algorithm for AMOLED Display Based on Residual Network Model Open
To ensure the uniformity of display image quality, it's necessary to gamma‐tuning, which is particularly time‐consuming, resulting in lower production efficiency. In order to reduce gamma TT (Tack Time), this paper proposes a novel AI mode…
View article: Antihypertensive Effect of Milk Fermented by Lactiplantibacillus plantarum K79 on Spontaneously Hypertensive Rats
Antihypertensive Effect of Milk Fermented by Lactiplantibacillus plantarum K79 on Spontaneously Hypertensive Rats Open
The aim of this study is to investigate whether milk fermented by Lactiplantibacillus plantarum K79, which exhibits angiotensin-converting enzyme inhibitory activity, has an effect on lowering the blood pressure of hypertensive rats and to…
View article: Fuel temperature and injection pressure influence on the cold start GDI sprays
Fuel temperature and injection pressure influence on the cold start GDI sprays Open
Cold start in gasoline direct injection engines (GDI) is a critical issue that significantly impacts fuel consumption and emissions. Therefore, it is essential to investigate and improve the spray and air-fuel mixing processes during cold …