Won Sub Kang
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View article: Association Between Gene Polymorphisms of RSPO2 of the Wnt Signaling Pathway and Schizophrenia in the Korean Population
Association Between Gene Polymorphisms of RSPO2 of the Wnt Signaling Pathway and Schizophrenia in the Korean Population Open
Objective The study aimed to investigate whether RSPO2 gene polymorphisms are associated with schizophrenia susceptibility, focusing on five specific single nucleotide polymorphisms (SNPs). Additionally, the study evaluated the expression …
View article: ASSOCIATION BETWEEN GENETIC POLYMORPHISMS OF WNT SIGNALING GENES AND SCHIZOPHRENIA IN A KOREAN POPULATION
ASSOCIATION BETWEEN GENETIC POLYMORPHISMS OF WNT SIGNALING GENES AND SCHIZOPHRENIA IN A KOREAN POPULATION Open
Background The disruption of the Wnt/β-catenin pathway has been involved in the pathogenesis of schizophrenia, dysregulating of brain development. R-spondin 2 (Rspo2), encoded by the RSPO2 gene, is a secreted ligand enhancing Wnt signaling…
View article: Awareness of Psychosomatic Medicine in Korea: Results From an Online Survey Conducted With Doctors and the General Public
Awareness of Psychosomatic Medicine in Korea: Results From an Online Survey Conducted With Doctors and the General Public Open
Doctors identified more PM-specific terms, whereas the general public had a vaguer understanding of PM. Even a brief education intervention significantly helped align the perceptions of both groups with current PM theory, highlighting the …
View article: Development of a Clinical Guideline for Suicide Prevention in Psychiatric Patients Based on the ADAPTE Methodology
Development of a Clinical Guideline for Suicide Prevention in Psychiatric Patients Based on the ADAPTE Methodology Open
The developed guidelines provide a structured, evidence-based approach to reducing suicide rates among psychiatric patients in Korea. Future research will focus on expanding these guidelines to include screening protocols for high-risk gro…
View article: Can Pre-Transplant Psychometric Testing Predict Tacrolimus Intrapatient Variability After Living Kidney Transplantation?
Can Pre-Transplant Psychometric Testing Predict Tacrolimus Intrapatient Variability After Living Kidney Transplantation? Open
Objective Tacrolimus intrapatient variability (Tac IPV) has been considered a marker for post-graft risk. We investigated pre-transplant psychometric testing to predict Tac IPV after living kidney transplantation.Methods Minnesota Multipha…
View article: Psychotropic Medications Promote Time-Dependent Reduction of Suicidal Ideation in Mood Disorder: A Prospective Cohort Study
Psychotropic Medications Promote Time-Dependent Reduction of Suicidal Ideation in Mood Disorder: A Prospective Cohort Study Open
Adequate psychotropic medication may reduce suicidal ideation in patients with mood disorders aged 25 years and older. Additional research on psychotropic drugs is needed to effectively reduce the risk of suicide among children and adolesc…
View article: Development of a Guideline for Antipsychotic-induced Hyperprolactinemia in Korea Using the ADAPTE Process
Development of a Guideline for Antipsychotic-induced Hyperprolactinemia in Korea Using the ADAPTE Process Open
The development and dissemination of the adapted guideline is expected to increase the certainty of medical decision making and improve the quality of medical care. Further studies on the effectiveness and applicability of the developed gu…
View article: Empyema in a Patient with Schizophrenia Using Clozapine: A Case Report
Empyema in a Patient with Schizophrenia Using Clozapine: A Case Report Open
Schizophrenia is associated with a high risk of thoracic infections and pneumonia. The use of atypical antipsychotics clozapine may also increase the risk of pulmonary infection. However, psychotic patients are less likely to report physic…
View article: Effect of Multimodal Intervention Care on Cachexia in Patients with Advanced Cancer Compared To Conventional Management (MIRACLE): An Open-Label, Parallel, Randomized, Phase 2 Trial
Effect of Multimodal Intervention Care on Cachexia in Patients with Advanced Cancer Compared To Conventional Management (MIRACLE): An Open-Label, Parallel, Randomized, Phase 2 Trial Open
Background: the context and purpose of the studyCancer cachexia (CC) is a multifactorial process characterized by progressive weight loss, muscle mass, and fat tissue wasting, which adversely affects the quality of life and survival of pat…
View article: Identification of Brain Damage after Seizures Using an MR-Based Electrical Conductivity Imaging Method
Identification of Brain Damage after Seizures Using an MR-Based Electrical Conductivity Imaging Method Open
Previous imaging studies have shown the morphological malformation and the alterations of ionic mobility, water contents, electrical properties, or metabolites in seizure brains. Magnetic resonance electrical properties tomography (MREPT) …
View article: Early-Life Stress Modulates Gut Microbiota and Peripheral and Central Inflammation in a Sex-Dependent Manner
Early-Life Stress Modulates Gut Microbiota and Peripheral and Central Inflammation in a Sex-Dependent Manner Open
Recent studies have reported that changes in gut microbiota composition could induce neuropsychiatric problems. In this study, we investigated alterations in gut microbiota induced by early-life stress (ELS) in rats subjected to maternal s…
View article: Economic burden of eating disorders in South Korea
Economic burden of eating disorders in South Korea Open
Background Few studies have investigated the epidemiology of eating disorders using national representative data. In this study, we investigated the prevalence and economic burden of eating disorders in South Korea. Methods The aim of this…
View article: Depression, Anxiety, Related Risk Factors and Cognitive Distortion in Korean Patients with Inflammatory Bowel Disease
Depression, Anxiety, Related Risk Factors and Cognitive Distortion in Korean Patients with Inflammatory Bowel Disease Open
Objective To evaluate the severity of depression, anxiety, associated risk factors, and cognitive distortion in Korean patients with ulcerative colitis (UC) and Crohn’s disease (CD).Methods This study included 369 patients with inflammator…
View article: Economic burden of Eating disorders in South Korea
Economic burden of Eating disorders in South Korea Open
Objective Few studies have investigated the epidemiology of eating disorders using national representative data. In this study, we investigated the prevalence and economic burden of eating disorders in South Korea.Method The aim of this st…
View article: Association of the Promoter Haplotype of IFN-γ-Inducible Protein 16 Gene with Schizophrenia in a Korean Population
Association of the Promoter Haplotype of IFN-γ-Inducible Protein 16 Gene with Schizophrenia in a Korean Population Open
Objective Viral infections play an important role in the development of schizophrenia, inducing the faulty immunological responses and aberrant inflammation. IFN-γ-inducible protein 16 (IFI16) is an immunological DNA sensor against viral i…
View article: Differences in Personality, Defense Styles, and Coping Strategies in Individuals with Depressive Disorder According to Age Groups Across the Lifespan
Differences in Personality, Defense Styles, and Coping Strategies in Individuals with Depressive Disorder According to Age Groups Across the Lifespan Open
In the young age group associations with lower Agreeableness and Conscientiousness, as well as higher Neuroticism than the late middle age group were observed. Moreover, the young age group had a higher usage of immature defense style, and…
View article: The Development of Evidence-Based Guideline for Diagnosis and Management of Headache in Korea
The Development of Evidence-Based Guideline for Diagnosis and Management of Headache in Korea Open
Recommendations should be applied to actual clinical sites to achieve the ultimate goal of this guideline; therefore, follow-up activities, such as monitoring of guideline usage and assessment of applicability of the recommendations, shoul…
View article: Gray Matter Volume Reductions Were Associated with TPH1 Polymorphisms in Depressive Disorder Patients with Suicidal Attempts
Gray Matter Volume Reductions Were Associated with TPH1 Polymorphisms in Depressive Disorder Patients with Suicidal Attempts Open
These findings show the possibility that both GMV reductions and TPH1 rs1800532/rs1799913 A allele may be involved in the pathogenesis of depressive disorder patients with SA.
View article: [P2–119]: THE ASSOCIATION BETWEEN <i>CACNA1C</i> GENE POLYMORPHISM AND LATE‐ONSET ALZHEIMER's DISEASE IN THE KOREAN POPULATION
[P2–119]: THE ASSOCIATION BETWEEN <i>CACNA1C</i> GENE POLYMORPHISM AND LATE‐ONSET ALZHEIMER's DISEASE IN THE KOREAN POPULATION Open
Synaptic calcium dysregulation appears to play an important role in synaptic loss in Alzheimer's disease (AD). Previous studies implicated that the pathological cascade of Alzheimer's disease may be modified by interactions in the amyloid-…
View article: Factors Related to Noncompliance in Screening and Tracking Mild Cognitive Impairment Patients in a Single Community
Factors Related to Noncompliance in Screening and Tracking Mild Cognitive Impairment Patients in a Single Community Open
Considering the low dementia detection rate of the group who revisited only after contact and the reasons they gave for noncompliance, there appears to be a need for ongoing outreach and education regarding the course and prognosis of MCI.