L.C. Wong
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Author Swipe
View article: Promoter methylation of death-associated protein kinase and its role in irradiation response in cervical cancer
Promoter methylation of death-associated protein kinase and its role in irradiation response in cervical cancer Open
This study was aimed at investigating the death-associated protein kinase (DAPK) promoter methylation and its clinical relevance in cervical cancer. The DAPK promoter methylation was detected by methylation-specific PCR (MSP) and correlate…
View article: Effect of Individual Psychological Intervention in Chinese Women With Gynecologic Malignancy: A Randomized Controlled Trial
Effect of Individual Psychological Intervention in Chinese Women With Gynecologic Malignancy: A Randomized Controlled Trial Open
Purpose To evaluate the effectiveness of psychological intervention in the care of cancer patients and to determine whether routine use of individual psychological therapies is indicated. Patients and Methods Patients with newly diagnosed …
View article: High frequency of mitochondrial genome instability in human endometrial carcinomas
High frequency of mitochondrial genome instability in human endometrial carcinomas Open
To investigate the occurrence of somatic mitochondrial DNA (mtDNA) mutations in human primary endometrial carcinomas, we sequenced the D-loop region, the 12S and 16S rRNA genes of mtDNA of cancer tissues and their matched normal controls. …
View article: Wide local excision (WLE) for vaginal intraepithelial neoplasia (VAIN)
Wide local excision (WLE) for vaginal intraepithelial neoplasia (VAIN) Open
Ablative therapy for VAIN 3 is unsafe as occult invasive foci can be missed by biopsy. WLE is efficacious in treating high grade VAIN 3. Long term surveillance of the lower genital tract is needed to diagnose metachronous lesions.
View article: p21WAF1/CIP1 expression in gestational trophoblastic disease: correlation with clinicopathological parameters, and Ki67 and p53 gene expression.
p21WAF1/CIP1 expression in gestational trophoblastic disease: correlation with clinicopathological parameters, and Ki67 and p53 gene expression. Open
BACKGROUND: The p21WAF1/CIP1 gene mediates growth arrest by inhibiting G1 cyclin dependent kinases and has been considered as a downstream effector of the tumour suppressor gene p53. AIM: To analyse the role of p21WAF1/CIP1 in gestational …
View article: 4-epidoxorubicin in recurrent cervical cancer
4-epidoxorubicin in recurrent cervical cancer Open
Thirty-eight patients with histologically proven recurrent cervical cancer were treated with epirubicin, an analogue of anthracycline. There were eight complete responders and ten partial responders. The overall response rate was 47.8%. Th…
View article: Primary oral etoposide therapy in gestational trophoblastic disease: An update
Primary oral etoposide therapy in gestational trophoblastic disease: An update Open
Sixty patients who developed persistent or metastatic gestational trophoblastic disease (GTD) received primary oral etoposide therapy (VP 16-213). Twelve patients had metastatic GTD. Fifty-nine patients achieved biochemical remission. One …