Xiuming Wu
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View article: OTC-NET: A Multimodal Method for Accurate Diagnosis of Ovarian Cancer in O-RADS Category 4 Masses
OTC-NET: A Multimodal Method for Accurate Diagnosis of Ovarian Cancer in O-RADS Category 4 Masses Open
Background: Ovarian cancer is the deadliest female reproductive malignancy. Accurate preoperative differentiation of benign and malignant ovarian masses is critical for appropriate treatment. O-RADS category 4 lesions present a wide range …
View article: Heterologous Production of Forskolin in Tobacco ( <scp> <i>Nicotiana tabacum</i> </scp> ) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection
Heterologous Production of Forskolin in Tobacco ( <span> <i>Nicotiana tabacum</i> </span> ) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection Open
Plants are promising bioreactor for the sustainable and scalable production of high‐value natural bioactive compounds, because they can synthesise phytochemicals from CO 2 , light, water and minerals through their innate photosynthetic car…
View article: Ultrasound-based deep learning model as an assistant improves the diagnosis of ovarian tumors: a multicenter study
Ultrasound-based deep learning model as an assistant improves the diagnosis of ovarian tumors: a multicenter study Open
Background Deep learning (DL) models based on ultrasound (US) images can enhance the ability of radiologists to diagnose ovarian tumors. Materials and methods This retrospective study included 916 women with ovarian tumors in southeast Chi…
View article: Development and validation of a nomogram for diabetic tibial neuropathy based on ultrasound radiomics: a multicenter study
Development and validation of a nomogram for diabetic tibial neuropathy based on ultrasound radiomics: a multicenter study Open
Objective Diabetic tibial nerve neuropathy (DTN), a severe subtype of diabetic peripheral neuropathy, is often underdiagnosed in the early stages. This significantly raises the risks of foot ulcers and amputations. This study aims to devel…
View article: Risk factors for new vertebral fractures after percutaneous vertebroplasty or percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fractures
Risk factors for new vertebral fractures after percutaneous vertebroplasty or percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fractures Open
Object This study aims to conduct a prospective analysis of patients with osteoporotic vertebral compression fractures (OVCF) who underwent percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP), and further analyze the risk f…
View article: Heterologous biosynthesis of betanin triggers metabolic reprogramming in tobacco
Heterologous biosynthesis of betanin triggers metabolic reprogramming in tobacco Open
Engineering of a specialized metabolic pathway in plants is a promising approach to produce high-value bioactive compounds to address the challenges of climate change and population growth. Understanding the interaction between the heterol…
View article: MRI-based assessment paraspinal extensor muscle fatty infiltration in acute cervical spinal cord injury patients - a retrospective study
MRI-based assessment paraspinal extensor muscle fatty infiltration in acute cervical spinal cord injury patients - a retrospective study Open
View article: Multiplex Expression Cassette Assembly: A flexible and versatile method for building complex genetic circuits in conventional vectors
Multiplex Expression Cassette Assembly: A flexible and versatile method for building complex genetic circuits in conventional vectors Open
Summary The manipulation of multiple transcription units for simultaneous and coordinated expression is not only key to building complex genetic circuits to accomplish diverse functions in synthetic biology, but is also important in crop b…
View article: Transcriptomic profiling of dynamic alternative splicing during the early response to Ralstonia solanacearum infection in tobacco roots
Transcriptomic profiling of dynamic alternative splicing during the early response to Ralstonia solanacearum infection in tobacco roots Open
The pathogenic bacterium, Ralstonia solanacearum , causes bacterial wilt disease in many crops, which leads to significant yield losses worldwide. Although genes associated with resistance to this pathogen have been isolated and characteri…
View article: Chinese expert consensus on fetal ultrasound anatomical examination at 11 +0 to 13 +6 gestational weeks: results of the Delphi procedure
Chinese expert consensus on fetal ultrasound anatomical examination at 11 +0 to 13 +6 gestational weeks: results of the Delphi procedure Open
Background This study aimed to develop a standardized expert consensus on anatomical examination of first-trimester fetal ultrasound. Methods Based on the Delphi procedure, 122 experts from 27 grades of medical institutions throughout Chin…
View article: Transcriptome Analysis and Genome-Wide Gene Family Identification Enhance Insights into Bacterial Wilt Resistance in Tobacco
Transcriptome Analysis and Genome-Wide Gene Family Identification Enhance Insights into Bacterial Wilt Resistance in Tobacco Open
Bacterial wilt, caused by the Ralstonia solanacearum species complex, is one of the most damaging bacterial diseases in tobacco and other Solanaceae crops. In this study, we conducted an analysis and comparison of transcriptome landscape c…
View article: Identification and characterization of sub-group 4 R2R3-MYB members and their functions in phenylpropanoid and flavonoid regulation in tobacco
Identification and characterization of sub-group 4 R2R3-MYB members and their functions in phenylpropanoid and flavonoid regulation in tobacco Open
Sub-group 4 R2R3-type MYB transcription factors (TFs) are involved in repression of the phenylpropanoid pathway. In this study, we identified and characterized three MYB transcriptional repressors in common tobacco, named NtMYB1, NtMYB2, a…
View article: Comprehensive transcriptome and WGCNA analysis reveals the potential function of anthocyanins in low-temperature resistance of a red flower mutant tobacco
Comprehensive transcriptome and WGCNA analysis reveals the potential function of anthocyanins in low-temperature resistance of a red flower mutant tobacco Open
The anthocyanin is a protective substance in various plants, and plays important roles in resisting to low-temperature. Here, we explored transcriptome analysis of pink flower (as CK) and the natural mutant red flower (as research objects)…
View article: Detection of fetal facial anatomy in standard ultrasonographic sections based on real‐time target detection network
Detection of fetal facial anatomy in standard ultrasonographic sections based on real‐time target detection network Open
At present, prenatal ultrasound is one of the important means for screening fetal malformations. In the process of prenatal ultrasound diagnosis, the accurate recognition of fetal facial ultrasound standard plane is crucial for facial malf…
View article: Genome-wide analysis of UDP-glycosyltransferases family and identification of UGT genes involved in abiotic stress and flavonol biosynthesis in Nicotiana tabacum
Genome-wide analysis of UDP-glycosyltransferases family and identification of UGT genes involved in abiotic stress and flavonol biosynthesis in Nicotiana tabacum Open
Background Uridine disphosphate (UDP) glycosyltransferases (UGTs) act upon a huge variety of highly diverse and complex substrates, such as phytohormones and specialized metabolites, to regulate plant growth, development, disease resistanc…
View article: The Atomic Oxygen Resistant Study of a Transparent Polyimide Film Containing Phosphorus and Fluorine
The Atomic Oxygen Resistant Study of a Transparent Polyimide Film Containing Phosphorus and Fluorine Open
View article: Transcriptomic Analysis of the Molecular Mechanism of Low-Temperature Resistance in a Red Flower Mutant of Tobacco
Transcriptomic Analysis of the Molecular Mechanism of Low-Temperature Resistance in a Red Flower Mutant of Tobacco Open
View article: Bromoperoxidase Mimicry Based on Bi2o2.33 Nanosheets for Aptasensing
Bromoperoxidase Mimicry Based on Bi2o2.33 Nanosheets for Aptasensing Open
View article: Development and Application of a Novel Simple Sequence Repeat Mining Algorithm Based on Regular Expression
Development and Application of a Novel Simple Sequence Repeat Mining Algorithm Based on Regular Expression Open
Simple sequence repeats (SSRs) are molecular genetic markers that are powerful tools in genomics studies; SSR markers are routinely mined as a part of genetic workflows. Here, we developed a novel SSR mining algorithm based on regular expr…
View article: Comprehensive Analysis Reveals the Genetic and Pathogenic Diversity of Ralstonia solanacearum Species Complex and Benefits Its Taxonomic Classification
Comprehensive Analysis Reveals the Genetic and Pathogenic Diversity of Ralstonia solanacearum Species Complex and Benefits Its Taxonomic Classification Open
Ralstonia solanacearum species complex (RSSC) is a diverse group of plant pathogens that attack a wide range of hosts and cause devastating losses worldwide. In this study, we conducted a comprehensive analysis of 131 RSSC strains to detec…
View article: Toward Hydrogen‐Free and Dendrite‐Free Aqueous Zinc Batteries: Formation of Zincophilic Protective Layer on Zn Anodes
Toward Hydrogen‐Free and Dendrite‐Free Aqueous Zinc Batteries: Formation of Zincophilic Protective Layer on Zn Anodes Open
Rechargeable aqueous Zn‐ion batteries (ZIBs) are regarded as one of the most promising devices for the next‐generation energy storage system. However, the uncontrolled dendrite growth on Zn metal anodes and the side hydrogen evolution reac…
View article: Comparative evaluation of 19 reverse transcription loop-mediated isothermal amplification assays for detection of SARS-CoV-2
Comparative evaluation of 19 reverse transcription loop-mediated isothermal amplification assays for detection of SARS-CoV-2 Open
View article: A Benign and Malignant Breast Tumor Classification Method via Efficiently Combining Texture and Morphological Features on Ultrasound Images
A Benign and Malignant Breast Tumor Classification Method via Efficiently Combining Texture and Morphological Features on Ultrasound Images Open
The classification of benign and malignant based on ultrasound images is of great value because breast cancer is an enormous threat to women’s health worldwide. Although both texture and morphological features are crucial representations o…
View article: Comparative Evaluation of 19 Reverse Transcription Loop-Mediated Isothermal Amplification Assays for Detection of SARS-CoV-2
Comparative Evaluation of 19 Reverse Transcription Loop-Mediated Isothermal Amplification Assays for Detection of SARS-CoV-2 Open
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has caused a global pandemics. To facilitate the detection of SARS-CoV-2 infection, various RT-LAMP assays using 19 sets of primers had been developed, but never been compared. We pe…
View article: Epidemiological and clinical characteristics of COVID-19 patients in Nantong, China
Epidemiological and clinical characteristics of COVID-19 patients in Nantong, China Open
Introduction: COVID-19 is a newly emerging life-threatening respiratory disease caused by a newly identified coronavirus SARS-CoV-2.
Methodology: We included 28 COVID-19 patients admitted to Nantong Third Hospital from January 23 to Febru…
View article: Correction to: Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2
Correction to: Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2 Open
View article: A Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2
A Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2 Open
COVID-19 has become a major global public health burden, currently causing a rapidly growing number of infections and significant morbidity and mortality around the world. Early detection with fast and sensitive assays and timely intervent…
View article: Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2
Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2 Open
Jiang and Shi 2020).Similar to severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), the new coronavirus also belongs to Betacoronavirus, and shares highest sequence identity …
View article: Optically Transparent and Thermal‐Stable Polyimide Films Derived from a Semi‐Aliphatic Diamine: Synthesis and Properties
Optically Transparent and Thermal‐Stable Polyimide Films Derived from a Semi‐Aliphatic Diamine: Synthesis and Properties Open
A novel semi‐aliphatic diamine with bulky cyclohexyl and ortho ‐substituted tertiary butyl groups (4,4'‐(cyclohexylmethylene)bis(2‐( tert ‐butyl)aniline), CHMBTBA) is synthesized via Mannich and rearrangement reactions of cyclohexanecarbox…
View article: In Situ Enzymatically Generated Photoswitchable Oxidase Mimetics and Their Application for Colorimetric Detection of Glucose Oxidase
In Situ Enzymatically Generated Photoswitchable Oxidase Mimetics and Their Application for Colorimetric Detection of Glucose Oxidase Open
In this study, a simple and amplified colorimetric assay is developed for the detection of the enzymatic activity of glucose oxidase (GOx) based on in situ formation of a photoswitchable oxidase mimetic of PO43−-capped CdS quantum dots (QD…