Yongning Wu
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View article: What Are the Drivers Triggering Antimicrobial Resistance Emergence and Spread? Outlook from a One Health Perspective
What Are the Drivers Triggering Antimicrobial Resistance Emergence and Spread? Outlook from a One Health Perspective Open
Antimicrobial resistance (AMR) has emerged as a critical global public health threat, exacerbating healthcare burdens and imposing substantial economic costs. Currently, AMR contributes to nearly five million deaths annually worldwide, sur…
View article: Exploring Single-Atom Nanozymes Toward Environmental Pollutants: Monitoring and Control
Exploring Single-Atom Nanozymes Toward Environmental Pollutants: Monitoring and Control Open
View article: NDM-5-carried outer membrane vesicles impair the efficacy of antibiotics against bacterial infections
NDM-5-carried outer membrane vesicles impair the efficacy of antibiotics against bacterial infections Open
The intensifying use of antimicrobials in the rapidly growing livestock industry has heightened concerns over the proliferation of antibiotic resistance, particularly among Enterobacteriaceae producing β-lactamase. Elucidating the role of …
View article: Mitigation of Zearalenone-induced Hepatocyte Toxicity by Peroxidase and Laccase: Insights from Enzymatic Detoxification Study
Mitigation of Zearalenone-induced Hepatocyte Toxicity by Peroxidase and Laccase: Insights from Enzymatic Detoxification Study Open
View article: Morphological variability of Escherichia coli colonizing human wounds: a case report
Morphological variability of Escherichia coli colonizing human wounds: a case report Open
View article: Editorial: Global excellence in toxicology: Asia, Australia and New Zealand
Editorial: Global excellence in toxicology: Asia, Australia and New Zealand Open
View article: A High-Throughput Biosensing Approach for Rapid Screening of Compounds Targeting the hNav1.1 Channel: Marine Toxins as a Case Study
A High-Throughput Biosensing Approach for Rapid Screening of Compounds Targeting the hNav1.1 Channel: Marine Toxins as a Case Study Open
Voltage-gated sodium (Nav) channels play a crucial role in initiating and propagating action potentials throughout the heart, muscles and nervous systems, making them targets for a number of drugs and toxins. While patch-clamp electrophysi…
View article: Toxicological mechanisms of carbon polymers in accelerating cognitive decline in Alzheimer’s disease
Toxicological mechanisms of carbon polymers in accelerating cognitive decline in Alzheimer’s disease Open
View article: Regional antimicrobial resistance gene flow among the One Health sectors in China
Regional antimicrobial resistance gene flow among the One Health sectors in China Open
View article: Molecular Epidemiology of Type F <i>Clostridium perfringens</i> Among Diarrheal Patients and Virulence-Resistance Dynamics — 11 Provinces, China, 2024
Molecular Epidemiology of Type F <i>Clostridium perfringens</i> Among Diarrheal Patients and Virulence-Resistance Dynamics — 11 Provinces, China, 2024 Open
This investigation predominantly identified Type F C. perfringens in human clinical cases, with sporadic detection in pets and food products. These findings highlight the emergence of Type F C. perfringens outbreaks among dia…
View article: Chemical and Functional Heterogeneity in Ginger-Derived Exosome-Like Nanovesicles Across Cultivars: Toward Quality Standardization
Chemical and Functional Heterogeneity in Ginger-Derived Exosome-Like Nanovesicles Across Cultivars: Toward Quality Standardization Open
View article: The Genomic Characteristics of Dominant Salmonella Enterica Serovars from Retail Pork in Sichuan Province, China
The Genomic Characteristics of Dominant Salmonella Enterica Serovars from Retail Pork in Sichuan Province, China Open
View article: A Milk Extracellular Vesicle‐Based Nanoplatform Enhances Combination Therapy Against Multidrug‐Resistant Bacterial Infections
A Milk Extracellular Vesicle‐Based Nanoplatform Enhances Combination Therapy Against Multidrug‐Resistant Bacterial Infections Open
The increasing occurrence of infections caused by multidrug‐resistant (MDR) bacteria drives the need for new antibacterial drugs. Due to the current lack of antibiotic discovery and development, new strategies to fight MDR bacteria are urg…
View article: An interpretable machine learning model for precise prediction of biomarkers for intermittent fasting pattern
An interpretable machine learning model for precise prediction of biomarkers for intermittent fasting pattern Open
View article: Benchmark Dose Estimation from Transcriptomics Data for Methylimidazolium Ionic Liquid Hepatotoxicity: Implications for Health Risk Assessment of Green Solvents
Benchmark Dose Estimation from Transcriptomics Data for Methylimidazolium Ionic Liquid Hepatotoxicity: Implications for Health Risk Assessment of Green Solvents Open
Ionic liquids (ILs), traditionally considered environmentally benign solvents, have shown potential toxicity to organisms, raising concerns about their safety. Among them, 1-octyl-3-methylimidazolium (M8OI) has been detected at high concen…
View article: Preparation of sulfonic acid functionalized metal organic frameworks and their application in the online solid phase extraction of parabens and sulfonamides in pre-cooked foods
Preparation of sulfonic acid functionalized metal organic frameworks and their application in the online solid phase extraction of parabens and sulfonamides in pre-cooked foods Open
View article: High carriage and possible hidden spread of multidrug-resistant Salmonella among asymptomatic workers in Yulin, China
High carriage and possible hidden spread of multidrug-resistant Salmonella among asymptomatic workers in Yulin, China Open
Food workers have frequent contact with unprocessed foods, but their carriage of Salmonella and potential influence on public health have not been comprehensively assessed. We investigated Salmonella carriage among food workers compared wi…
View article: WITHDRAWN: Fungi-metabolites production and networking analysis in saprophytes and pathogens fungi
WITHDRAWN: Fungi-metabolites production and networking analysis in saprophytes and pathogens fungi Open
Fungi are important parasitic microorganism of plants, which mainly include saprophytes and pathogens species. However, differences of mycotoxins production by different fungi still remain challenging. To address this bottleneck, saprophyt…
View article: 9330 Atumelnant (crn04894) Induces Rapid And Sustained Reductions In Serum And Urine Cortisol In Patients With Acth-Dependent Cushing Syndrome During A Phase 1b/2a, Single Center, 10-day, Inpatient, Open-Label Study
9330 Atumelnant (crn04894) Induces Rapid And Sustained Reductions In Serum And Urine Cortisol In Patients With Acth-Dependent Cushing Syndrome During A Phase 1b/2a, Single Center, 10-day, Inpatient, Open-Label Study Open
Disclosure: H. Elenius: Grant Recipient; Self; Crinetics Pharmaceuticals, Inc. R. McGlotten: Grant Recipient; Self; Crinetics Pharmaceuticals, Inc. C. Moore: Grant Recipient; Self; Crinetics Pharmaceuticals, Inc. Y.B. Omotosho: Grant Recip…
View article: Innovative 3D microfluidic intestinal organoid model for assessing cadmium bioavailability in food: implications for enhanced exposure risk assessment
Innovative 3D microfluidic intestinal organoid model for assessing cadmium bioavailability in food: implications for enhanced exposure risk assessment Open
Given the severe toxicity and widespread presence of cadmium (Cd) in staple foods such as rice, accurate dietary exposure assessments are imperative for public health. In vitro bioavailability is commonly used to adjust dietary exposure le…
View article: Serum trace elements show association with thyroperoxidase autoantibodies in Thyroid Imaging Reporting and Data System (TI-RADS) 4 nodules
Serum trace elements show association with thyroperoxidase autoantibodies in Thyroid Imaging Reporting and Data System (TI-RADS) 4 nodules Open
Thyroid nodule (TN) has been becoming a great concern worldwide due to its high incidence. Although some studies have reported associations between trace elements exposure and the risk of TNs, the linkage was not inconclusive. The present …
View article: Impact of enniatins and beauvericin on lipid metabolism: Insights from a 3D HepaRG spheroid model
Impact of enniatins and beauvericin on lipid metabolism: Insights from a 3D HepaRG spheroid model Open
Emerging mycotoxins enniatins (ENNs) and beauvericin (BEA) pose potential health risks to humans through dietary exposure. However, research into their mechanisms of toxicity is limited, with a lack of comprehensive toxicological data. Thi…
View article: The Distribution and Pollution Pathway Analysis of Perfluoroalkyl Acids (PFAAs) in a Typical Agricultural Plastic Greenhouse for Cultivated Vegetables
The Distribution and Pollution Pathway Analysis of Perfluoroalkyl Acids (PFAAs) in a Typical Agricultural Plastic Greenhouse for Cultivated Vegetables Open
Plastic greenhouses play an important role in vegetable cultivation in China. While evaluations have attributed perfluoroalkyl acid contamination in greenhouse vegetables primarily to irrigation water, the potential contribution from green…
View article: Screening for compounds with bioaccumulation potential in breast milk using their retention behavior in two-dimensional gas chromatography
Screening for compounds with bioaccumulation potential in breast milk using their retention behavior in two-dimensional gas chromatography Open
Discovery of emerging pollutants in breast milk will be helpful for understanding the hazards to human health. However, it is difficult to identify key compounds among thousands present in complex samples. In this study, a method for scree…
View article: Improving physical stability of microalgae protein-based emulsions under acidic and neutral conditions via carboxymethyl chitosan complexation
Improving physical stability of microalgae protein-based emulsions under acidic and neutral conditions via carboxymethyl chitosan complexation Open
View article: A promising metabolite, 9-aminominocycline, restores the sensitivity of tigecycline against tet(X4)-positive Escherichia coli
A promising metabolite, 9-aminominocycline, restores the sensitivity of tigecycline against tet(X4)-positive Escherichia coli Open
The emergence and widespread of tigecycline resistance undoubtedly poses a serious threat to public health globally. The exploration of combination therapies has become preferred antibacterial strategies to alleviate this global burden. In…
View article: Benchmark Dose for Dioxin Based on Gestational Diabetes Mellitus Using Coexposure Statistical Methods and an Optimized Physiologically Based Toxicokinetic Model
Benchmark Dose for Dioxin Based on Gestational Diabetes Mellitus Using Coexposure Statistical Methods and an Optimized Physiologically Based Toxicokinetic Model Open
Dioxins are ubiquitous endocrine-disrupting substances, but determining the effects and benchmark doses in situations of coexposure is highly challenging. The objective of this study was to assess the relationship between dioxin andgestati…
View article: A Straightforward, Sensitive, and Reliable Strategy for Ethyl Carbamate Detection in By-Products from Baijiu Production by Enzyme-Linked Immunosorbent Assay
A Straightforward, Sensitive, and Reliable Strategy for Ethyl Carbamate Detection in By-Products from Baijiu Production by Enzyme-Linked Immunosorbent Assay Open
Baijiu is a renowned Chinese distilled liquor, notable for its distinctive flavor profile and intricate production process, which prominently involves fermentation and distillation. Ethyl carbamate (EC), a probable human carcinogen, can be…
View article: Correlations of IL-1 and IL-6 Gene polymorphisms with hypertrophiccardiomyopathy
Correlations of IL-1 and IL-6 Gene polymorphisms with hypertrophiccardiomyopathy Open
The purpose of this study was to explore the correlations of interleukin-1 (IL-1) and IL-6 gene polymorphisms with hypertrophic cardiomyopathy (HCM). A total of 200 patients with HCM were enrolled as disease group, and 200 healthy individu…
View article: New food sources and production systems: a comparison of international regulations and China’s advancements in novel foods with synthetic biology
New food sources and production systems: a comparison of international regulations and China’s advancements in novel foods with synthetic biology Open
The global shift towards sustainable food systems has sparked innovations in food sources and production systems, including cell-based meat, plant-based food products, precision fermentation, and 3D food printing. These advancements pose r…