Explanipedia

Robotic Needle Steering for Percutaneous Interventions: Sensing, Modeling, and Control Open

Fang-Jiao Zhao, Rui‐Xue Xu, Wujun Zhao, Xi‐Ming Sun, Yu Sun , et al. · 2025

Robotic needle steering plays a critical role in improving the precision and safety of percutaneous interventions across various clinical applications. However, manual needle steering remains challenged by operator‐dependent variability, p…

Commentary on “The role of phenotypic age acceleration in aneurysmal subarachnoid hemorrhage: analysis of retrospective data from two hospital-based cohorts and prospective UK Biobank cohort” Open

Chuanyi Zhang, Yongxu Zhang, Longbi Liu, Wujun Zhao · 2025

Commentary on “Radiomics and machine learning model for predicting overall survival in IDH wild-type glioblastoma after gross total resection: a multicenter study” Open

Chuanyi Zhang, Longbi Liu, Zhen Wang, Wujun Zhao · 2025

CTC-Race: Single-Cell Motility Assay of Circulating Tumor Cells from Metastatic Lung Cancer Patients Open

Yang Liu, Wujun Zhao, Jamie Hodgson, Mary G. Egan, Christen N. Cooper Pope , et al. · 2024

Distinctive subpopulations of circulating tumor cells (CTCs) with increased motility are considered to possess enhanced tumor-initiating potential and contribute to metastasis. Single-cell analysis of the migratory CTCs may increase our un…

Spatiotemporal dynamics of cellulose during enzymatic hydrolysis studied by infrared spectromicroscopy Open

Tina Jeoh, Jennifer Nill, Wujun Zhao, Sankar Raju Narayanasamy, Liang Chen , et al. · 2023

Spatial and temporal resolved mapping of infrared spectra of cellulose during enzymatic hydrolysis towards developing sustainable bioconversion processes to materials, fuels, and chemicals.

Focused ultrasound combined with miR-1208-equipped exosomes inhibits malignant progression of glioma Open

Ying Zhan, Yichen Song, Wei Qiao, Lu Sun, Xin Wang , et al. · 2023

Spatiotemporal Dynamics of Cellulose During Enzymatic Hydrolysis Studied by Infrared Spectromicroscopy Open

Tina Jeoh, Jennifer Nill, Wujun Zhao, Sankar Raju Narayanasamy, Liang Chen , et al. · 2023

AN OPEN-CHANEL MICROFLUIDIC MEMBRANE DEVICE FOR IN SITU HYPERSPECTRAL MAPPING OF ENZYMATIC CELLULOSE HYDROLYSIS Open

Hoi‐Ying N. Holman, Wujun Zhao, Jennifer Nill, Liang Chen, Sankar Raju Narayanasamy , et al. · 2021

Synchrotron infrared hyperspectral microscopy is a label-free and non-invasive technique well suited for imaging\nof chemical events in situ. It can track the spatial and temporal distributions of molecules of interests in a specimen\nin i…

An Open-channel Microfluidic Membrane Device for In situ Hyperspectral mapping of enzymatic cellulose hydrolysis Open

Hoi‐Ying N. Holman, Wujun Zhao, Jennifer D. Nill, Liang Chen, Sankar Raju Narayanasamy , et al. · 2021

Synchrotron infrared hyperspectral microscopy is a label-free and non-invasive technique well suited for imaging of chemical events in situ. It can track the spatial and temporal distributions of molecules of interests in a specimen in its…

CircRNA SRRM4 Regulates the Alternative Splicing of <i>PKM</i> and Promotes Aerobic Glycolysis via Deubiquitination of SRSF3 in Epilepsy Open

Wujun Zhao, Han Li, Miaomiao Li, Shuai wang, Li Zhuang , et al. · 2021

Fundamentals of integrated ferrohydrodynamic cell separation in circulating tumor cell isolation Open

Yang Liu, Wujun Zhao, Rui Cheng, Bryana N. Harris, Jonathan R. Murrow , et al. · 2021

We present the fundamental theory and experimental validations of an integrated ferrohydrodynamic cell separation (iFCS) method that can isolate circulating tumor cells with a high recovery rate.

Label-free ferrohydrodynamic separation of exosome-like nanoparticles Open

Yang Liu, Wujun Zhao, Rui Cheng, Meghan Logun, Maria del Mar Zayas-Viera , et al. · 2020

Particle ferrohydrodynamics and its device (FerroChip) enables label-free and size-dependent separation of exosome-like nanoparticles with high recovery rate and purity.

Surfen‐mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblastoma invasion Open

Meghan Logun, Kallie E. Wynens, Gregory Simchick, Wujun Zhao, Leidong Mao , et al. · 2019

Invasive spread of glioblastoma (GBM) is linked to changes in chondroitin sulfate (CS) proteoglycan (CSPG)‐associated sulfated glycosaminoglycans (GAGs) that are selectively up‐regulated in the tumor microenvironment (TME). We hypothesized…

Single Cell Manipulation: Manipulation of Single Cells Using a Ferromagnetic Nanorod Cluster Actuated by Weak AC Magnetic Fields (Adv. Biosys. 1/2019) Open

Lu Zhu, Weijie Huang, Fengchang Yang, Lei Yin, Shenxuan Liang , et al. · 2019

In article number 1800246, Yiping Zhao and co-workers demonstrate a unique non-contact single cell manipulation technique based on the actuation of magnetic nanorods or clusters by non-uniform alternating magnetic fields. This single cell …

Tumor antigen-independent and cell size variation-inclusive enrichment of viable circulating tumor cells Open

Wujun Zhao, Yang Liu, Brittany D. Jenkins, Rui Cheng, Bryana N. Harris , et al. · 2019

Integrated ferrohydrodynamic cell separation (iFCS) explores cell magnetization in biocompatible ferrofluids and enriches CTCs in an antigen-independent and cell size variation-inclusive manner.

Manipulation of Single Cells Using a Ferromagnetic Nanorod Cluster Actuated by Weak AC Magnetic Fields Open

Lu Zhu, Weijie Huang, Fengchang Yang, Lei Yin, Shenxuan Liang , et al. · 2018

A unique noncontact single cell manipulation technique based on the actuation of magnetic nanorods (MNRs) or clusters (MCs) by nonuniform alternating magnetic fields (nuAMFs) is demonstrated. Compared to the actuation of MNRs/MCs by conven…

Microfluidics in Malignant Glioma Research and Precision Medicine Open

Meghan Logun, Wujun Zhao, Leidong Mao, Lohitash Karumbaiah · 2018

Glioblastoma multiforme (GBM) is an aggressive form of brain cancer that has no effective treatments and a prognosis of only 12–15 months. Microfluidic technologies deliver microscale control of fluids and cells, and have aided cancer ther…

Label-free ferrohydrodynamic cell separation of circulating tumor cells Open

Wujun Zhao, Rui Cheng, Brittany D. Jenkins, Τao Zhu, Nneoma E. Okonkwo , et al. · 2017

A size-based ferrohydrodynamic cell separation (FCS) device capable of enriching intact circulating tumor cells with high throughput and high recovery rate.

Biocompatible and label-free separation of cancer cells from cell culture lines from white blood cells in ferrofluids Open

Wujun Zhao, Rui Cheng, So Hyun Lim, Joshua R. Miller, Weizhong Zhang , et al. · 2017

A biocompatible and label-free method for separation of low-concentration cancer cells from cell lines from white blood cells is developed.

Label‐Free Microfluidic Manipulation of Particles and Cells in Magnetic Liquids Open

Wujun Zhao, Rui Cheng, Joshua R. Miller, Leidong Mao · 2016

Manipulating particles and cells in magnetic liquids through “negative magnetophoresis” is a new research field. It has resulted in label‐free and low‐cost manipulation techniques in microfluidic systems and many exciting applications. It …

Glioma cell invasion is significantly enhanced in composite hydrogel matrices composed of chondroitin 4- and 4,6-sulfated glycosaminoglycans Open

Meghan Logun, Nicole S. Bisel, Emily A. Tanasse, Wujun Zhao, Bhagya Gunasekera , et al. · 2016

Glioblastoma multiforme (GBM) is the most aggressive form of astrocytoma accounting for a majority of primary malignant brain tumors in the United States.

Label‐Free and Continuous‐Flow Ferrohydrodynamic Separation of HeLa Cells and Blood Cells in Biocompatible Ferrofluids Open

Wujun Zhao, Taotao Zhu, Rui Cheng, Yufei Liu, Jian He , et al. · 2015

In this study, a label‐free, low‐cost, and fast ferrohydrodynamic cell separation scheme is demonstrated using HeLa cells (an epithelial cell line) and red blood cells. The separation is based on cell size difference, and conducted in a cu…

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