Explanipedia

Brain Perfusion Imaging of a Large Population: Arterial Spin Labelling MRI in UK Biobank Open

Thomas W. Okell, Xinyi Xu, Martin Craig, Fidel Alfaro‐Almagro, David L. Thomas , et al. · 2025

Blood flow to the brain is a sensitive marker of neuronal activity as well as of a number of diseases, including stroke, tumours and neurodegenerative conditions. Arterial spin labelling (ASL) is a non-invasive magnetic resonance imaging (…

Heterogeneous Neurophenotypes of Adolescent Sleep Insufficiency Stratify Natural Short Sleepers from Comorbidity or Environment Driven Insufficiency Open

Dan Wu, Yiwei Chen, Mingyang Li, Zhiyong Zhao, Xinyi Xu , et al. · 2025

Insufficient sleep has become an increasing public health issue in adolescents, which is associated with complex social-ecological factors and a wide range of neurodevelopmental outcomes. The highly heterogeneous determinants and outcomes …

Watching Positive Videos Facilitates Mental Fatigue Recovery: A Task fMRI Study Open

Xiaoyu Li, Kuijun Wu, Linze Qian, Sujie Wang, Xinyi Xu , et al. · 2025

Timely intervention for mental fatigue is necessary to mitigate adverse consequences and promote rapid recovery. As the mobile internet and new media platforms rapidly expand, people are increasingly watching videos during breaks. While po…

A Ship-Shaped Smart Microneedle Robot for Enhanced Gastric Drug Delivery Open

Jingjing Luo, Shuyue Deng, Shibo Zhang, Yanbing Zhao, Xinyi Xu , et al. · 2025

AtlasSeg: Atlas Prior Guided Dual-U-Net for Cortical Segmentation in Fetal Brain MRI Open

Haoan Xu, Tianshu Zheng, Xinyi Xu, Shen Yao, Jiwei Sun , et al. · 2024

Accurate automatic tissue segmentation in fetal brain MRI is a crucial step in clinical diagnosis but remains challenging, particularly due to the dynamically changing anatomy and tissue contrast during fetal development. Existing segmenta…

Age-dependent functional development pattern in neonatal brain: An fMRI-based brain entropy study Open

Zhiyong Zhao, Yifan Shuai, Yihan Wu, Xinyi Xu, Mingyang Li , et al. · 2024

The relationship between brain entropy (BEN) and early brain development has been established through animal studies. However, it remains unclear whether the BEN can be used to identify age-dependent functional changes in human neonatal br…

Development of the Fetal Brain Corticocortical Structural Network during the Second-to-Third Trimester Based on Diffusion MRI Open

Ruike Chen, Ruoke Zhao, Haotian Li, Xinyi Xu, Mingyang Li , et al. · 2024

During the second-to-third trimester, the neuronal pathways of the fetal brain experience rapid development, resulting in the complex architecture of the interwired network at birth. While diffusion MRI-based tractography has been employed…

Cognitive processing speed and accuracy are intrinsically different in genetic architecture and brain phenotypes Open

Mingyang Li, Xixi Dang, Yiwei Chen, Zhifan Chen, Xinyi Xu , et al. · 2024

Since the birth of cognitive science, researchers have used reaction time and accuracy to measure cognitive ability. The initial use of these two measures is probably a generalization from empiricism, but it also implies that most cognitiv…

Causal Relationships Between Screen Use, Reading, and Brain Development in Early Adolescents Open

Mingyang Li, Ruoke Zhao, Xixi Dang, Xinyi Xu, Ruike Chen , et al. · 2024

The rise of new media has greatly changed the lifestyles, leading to increased time on these platforms and less time spent reading. This shift has particularly profound impacts on early adolescents, who are in a critical stage of brain dev…

Site Effects in Multisite Fetal Brain MRI: Morphological Insights into Early Brain Development Open

Xinyi Xu, Cong Sun, Yu Hong, Guohui Yan, Qingqing Zhu , et al. · 2023

Background Multisite MRI studies have become prevalent given their advantage in revealing reliable biological or clinical findings. Adult and adolescent multisite studies have demonstrated inevitable site-related non-biological effects tha…

Developmental pattern of individual morphometric similarity network in the human fetal brain Open

Ruoke Zhao, Cong Sun, Xinyi Xu, Zhiyong Zhao, Mingyang Li , et al. · 2023

The development of the cerebral cortex during the fetal period is a complex yet well-coordinated process. MRI-based morphological brain network provides a powerful tool for describing this process at a network level. Due to the challenges …

The causal effect of screen uses versus reading on the brain development in early adolescents Open

Mingyang Li, Ruoke Zhao, Xinyi Xu, Ruike Chen, Yiwei Chen , et al. · 2023

The rise of new media has greatly changed our lifestyles, leading to increased time spent on these digital platforms and less time spent reading. This shift has a particularly profound impact on children and adolescents, who are in a criti…

Fetal brain tissue annotation and segmentation challenge results Open

Kelly Payette, Hongwei Li, Priscille de Dumast, Roxane Licandro, Hui Ji , et al. · 2023

Multi-modal multi-resolution atlas of the human neonatal cerebral cortex based on microstructural similarity Open

Mingyang Li, Xinyi Xu, Zuozhen Cao, Ruike Chen, Ruoke Zhao , et al. · 2023

The neonatal period is a critical window for the development of the human brain and may hold implications for the long-term development of cognition and disorders. Multi-modal connectome studies have revealed many important findings underl…

Multi-modal multi-resolution atlas of the human neonatal cerebral cortex based on microstructural similarity Open

Mingyang Li, Xinyi Xu, Zuozhen Cao, Ruike Chen, Ruoke Zhao , et al. · 2022

The neonatal period is a critical window for the development of the human brain and may hold implications for the long-term development of cognition and disorders. Multi-modal connectome studies have revealed many important findings underl…

Spatiotemporal Atlas of the Fetal Brain Depicts Cortical Developmental Gradient Open

Xinyi Xu, Cong Sun, Jiwei Sun, Wen Shi, Yao Shen , et al. · 2022

The fetal brains experience rapid and complex development in utero during the second and third trimesters. In utero MRI of the fetal brain in this period enables us to quantify normal fetal brain development in the spatiotemporal domain. I…

Development of visual cortex in human neonates is selectively modified by postnatal experience Open

Mingyang Li, Tingting Liu, Xinyi Xu, Qingqing Wen, Zhiyong Zhao , et al. · 2022

Experience-dependent cortical plasticity is a pivotal process of human brain development and essential for the formation of most cognitive functions. Although studies found that early visual experience could influence the endogenous develo…

AFFIRM: Affinity Fusion-Based Framework for Iteratively Random Motion Correction of Multi-Slice Fetal Brain MRI Open

Wen Shi, Haoan Xu, Cong Sun, Jiwei Sun, Yamin Li , et al. · 2022

Multi-slice magnetic resonance images of the fetal brain are usually contaminated by severe and arbitrary fetal and maternal motion. Hence, stable and robust motion correction is necessary to reconstruct high-resolution 3D fetal brain volu…

Spatiotemporal atlas of the fetal brain depicts cortical developmental gradient in Chinese population Open

Xinyi Xu, Cong Sun, Jiwei Sun, Wen Shi, Yao Shen , et al. · 2022

The fetal brains experience rapid and complex development in utero during the second and third trimesters. MRI atlas of the fetal brain in this period enables us to quantify the normal fetal brain development in the spatiotemporal domain. …

Development of visual cortex in human neonates are selectively modified by postnatal experience Open

Mingyang Li, Tingting Liu, Xinyi Xu, Qingqing Wen, Zhiyong Zhao , et al. · 2022

Experience-dependent cortical plasticity is a pivotal process of human brain development and essential for the formation of most cognitive functions. Although studies found that early visual experience could influence the endogenous develo…

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