Xavier Bugaut
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View article: Bifunctional Iodoazolium Salts: Searching for Cooperation Between Halogen Bonding and Hydrogen Bonding
Bifunctional Iodoazolium Salts: Searching for Cooperation Between Halogen Bonding and Hydrogen Bonding Open
Non‐covalent interactions play an important role in all sub‐fields of chemistry, including catalysis, where interactions of different natures can work together to improve reactivitiy and selectivity. Several families of molecules that inco…
View article: Enantioselective Synthesis of Atropisomers by Oxidative Aromatization with Central-to-Axial Conversion of Chirality
Enantioselective Synthesis of Atropisomers by Oxidative Aromatization with Central-to-Axial Conversion of Chirality Open
Atropisomers are fascinating objects of study by themselves for chemists but also find applications in various sub-fields of applied chemistry. Obtaining them in enantiopure form is far from being a solved challenge, and the past decades h…
View article: CCDC 2173781: Experimental Crystal Structure Determination
CCDC 2173781: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2173780: Experimental Crystal Structure Determination
CCDC 2173780: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2173779: Experimental Crystal Structure Determination
CCDC 2173779: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Energy‐Efficient Iodine Uptake by a Molecular Host⋅Guest Crystal
Energy‐Efficient Iodine Uptake by a Molecular Host⋅Guest Crystal Open
Recently, porous organic crystals (POC) based on macrocycles have shown exceptional sorption and separation properties. Yet, the impact of guest presence inside a macrocycle prior to adsorption has not been studied. Here we show that the i…
View article: Energy‐Efficient Iodine Uptake by a Molecular Host⋅Guest Crystal
Energy‐Efficient Iodine Uptake by a Molecular Host⋅Guest Crystal Open
Recently, porous organic crystals (POC) based on macrocycles have shown exceptional sorption and separation properties. Yet, the impact of guest presence inside a macrocycle prior to adsorption has not been studied. Here we show that the i…
View article: Enantiospecific Syntheses of Congested Atropisomers through Chiral Bis(aryne) Synthetic Equivalents
Enantiospecific Syntheses of Congested Atropisomers through Chiral Bis(aryne) Synthetic Equivalents Open
The synthetic equivalents of the enantiopure binaphthyl bis(aryne) atropisomers derived from BINOL (1,1′‐bi‐2,2′‐naphtol) featuring a stereogenic axis vicinal to the two reactive triple bonds can be generated for the first time in solution…
View article: Frustrated behavior of Lewis/Brønsted pairs inside molecular cages
Frustrated behavior of Lewis/Brønsted pairs inside molecular cages Open
Small changes in the cavity size and shape allow for modulating the level of frustration of endohedrally functionalized cages.
View article: Hemicryptophane Cages with a <i>C</i><sub>1</sub>-Symmetric Cyclotriveratrylene Unit
Hemicryptophane Cages with a <i>C</i><sub>1</sub>-Symmetric Cyclotriveratrylene Unit Open
International audience
View article: The Chloroazaphosphatrane Motif for Halogen Bonding in Solution
The Chloroazaphosphatrane Motif for Halogen Bonding in Solution Open
Chloroazaphosphatranes, the corresponding halogenophosphonium cations of the Verkade superbases, were evaluated as a new motif for halogen bonding (XB). Their modulable synthesis allowed for synthetizing chloroazaphosphatranes with various…
View article: On the Enantioselective Phosphoric-Acid-Catalyzed Hantzsch Synthesis of Polyhydroquinolines
On the Enantioselective Phosphoric-Acid-Catalyzed Hantzsch Synthesis of Polyhydroquinolines Open
A reinvestigation of a chiral phosphoric-acid-catalyzed four-component Hantzsch enantioselective synthesis of polyhydroquinolines reported in 2009 is presented. In our hands, when the reaction was performed with fidelity to the original re…
View article: Azaphosphatranes Catalyzed Strecker Reaction in the Presence of Water
Azaphosphatranes Catalyzed Strecker Reaction in the Presence of Water Open
Azaphosphatranes were found to act as efficient organocatalysts in the presence of water for the cyanation of differently substituted imines. A relatively safer source of cyanide, trimethylsilyl cyanide (TMSCN), was used, and excellent yie…
View article: Enantioselective Organocatalyzed Michael Additions of Nitroalkanes to 4‐Arylidenedihydrofuran‐2,3‐diones and 4‐Arylidenepyrrolidine‐2,3‐diones
Enantioselective Organocatalyzed Michael Additions of Nitroalkanes to 4‐Arylidenedihydrofuran‐2,3‐diones and 4‐Arylidenepyrrolidine‐2,3‐diones Open
Tremendous efforts have been devoted to the development of organocatalytic enantioselective Michael additions of nitroalkanes to α,β‐unsaturated carbonyl compounds. However, using highly substituted electrophiles remain challenging, since …
View article: Weinreb β-Ketoamides in Enantioselective Organocatalysis: A Balance between Reactivity and Selectivity
Weinreb β-Ketoamides in Enantioselective Organocatalysis: A Balance between Reactivity and Selectivity Open
β-Dicarbonyl compounds have established themselves as substrates of choice in enantioselective organocatalysis because of their easy activation. Among them, β-diketones, β-diesters, and β-ketoesters lead the dance and there has been only l…
View article: Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy
Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy Open
For the first time, enantiomerically enriched atropoisomeric furans have been accessed using a central-to-axial chirality conversion strategy. Hence, oxidation of the enantioenriched dihydrofuran precursors gave rise to axially chiral fura…
View article: CCDC 1505558: Experimental Crystal Structure Determination
CCDC 1505558: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1505557: Experimental Crystal Structure Determination
CCDC 1505557: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1505556: Experimental Crystal Structure Determination
CCDC 1505556: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1505555: Experimental Crystal Structure Determination
CCDC 1505555: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Organocatalytic Multicomponent Reactions of 1,3-Dicarbonyls for the Synthesis of Enantioenriched Heterocycles
Organocatalytic Multicomponent Reactions of 1,3-Dicarbonyls for the Synthesis of Enantioenriched Heterocycles Open
International audience
View article: From Simple Cyclic 1,3-Ketoamides to Complex Spirolactams by Supported Heterogeneous Organocatalysis with PS-BEMP
From Simple Cyclic 1,3-Ketoamides to Complex Spirolactams by Supported Heterogeneous Organocatalysis with PS-BEMP Open
The reaction between cyclic 1,3-ketoamides and Michael acceptors in the presence of a catalytic amount of a polymer-supported organobase PS-BEMP has been developed for a direct access to spirocyclic 1,3-ketolactams through a domino Michael…
View article: Addition of silylated nucleophiles to α-oxoketenes
Addition of silylated nucleophiles to α-oxoketenes Open
A general evaluation of silylated nucleophiles to intercept transient α-oxoketenes generated by microwave-assisted Wolff rearrangement of 2-diazo-1,3-dicarbonyl compounds is presented.
View article: CCDC 1430278: Experimental Crystal Structure Determination
CCDC 1430278: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1429887: Experimental Crystal Structure Determination
CCDC 1429887: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1429886: Experimental Crystal Structure Determination
CCDC 1429886: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1056472: Experimental Crystal Structure Determination
CCDC 1056472: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …