Muriel Mercier‐Bonin
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View article: Repeated in vitro exposure to PFOA impairs intestinal barrier integrity and leads to cytosolic accumulation as detected by subcellular chemical imaging
Repeated in vitro exposure to PFOA impairs intestinal barrier integrity and leads to cytosolic accumulation as detected by subcellular chemical imaging Open
Perfluorooctanoic acid (PFOA) is a persistent organic pollutant recognised for its environmental presence and bioaccumulation, despite regulatory restrictions under the Stockholm Convention. While systemic effects of PFOA have been studied…
View article: Plastics used in agriculture and for food: uses, properties and impacts. Summary report of the collective scientific assessment
Plastics used in agriculture and for food: uses, properties and impacts. Summary report of the collective scientific assessment Open
View article: Plastiques utilisés en agriculture et pour l’alimentation : usages, propriétés et impacts. Rapport d’ESCo
Plastiques utilisés en agriculture et pour l’alimentation : usages, propriétés et impacts. Rapport d’ESCo Open
View article: How scientific networks can help advancing both scientific knowledge and public policies: the case study of the “Plastics, Environment and Health” network
How scientific networks can help advancing both scientific knowledge and public policies: the case study of the “Plastics, Environment and Health” network Open
The “Plastics, Environment and Health” research network (groupement de recherche, GDR) created in 2019 gathers the French scientific community working on plastic pollution in all environments (soil, air, water) and their impact on ecosyste…
View article: Postbiotic potential of <i>Lactococcus lactis</i> <scp>CNCM</scp> I‐5388 in alleviating visceral pain in female rat through <scp>GABA</scp> production: The innovative concept of the “active‐ <scp>GAD</scp> bag”
Postbiotic potential of <i>Lactococcus lactis</i> <span>CNCM</span> I‐5388 in alleviating visceral pain in female rat through <span>GABA</span> production: The innovative concept of the “active‐ <span>GAD</span> bag” Open
Irritable bowel syndrome (IBS) is a multifactorial disorder of the gut‐brain axis, characterized by visceral hypersensitivity (VH). Psychobiotics, through GABA synthesis, are good candidates to alleviate gastrointestinal discomfort. Here, …
View article: Gender-Specific chemical exposure in arctic communities
Gender-Specific chemical exposure in arctic communities Open
This review explores the challenges Arctic populations face regarding contaminant exposure and its intricate relationship with traditional diets. Particular attention is given to the unique situation of northern women, whose dietary habits…
View article: Plastiques utilisés en agriculture et pour l’alimentation : usages, propriétés et impacts. Synthèse du rapport d’ESCo
Plastiques utilisés en agriculture et pour l’alimentation : usages, propriétés et impacts. Synthèse du rapport d’ESCo Open
Plastics used in agriculture and for food: uses, properties and impacts. Condensed report of the collecive scientific assessment.
View article: When subcellular chemical imaging enlightens our understanding on intestinal absorption, intracellular fate and toxicity of PFOA in vitro
When subcellular chemical imaging enlightens our understanding on intestinal absorption, intracellular fate and toxicity of PFOA in vitro Open
View article: Plastics used in agriculture and for food: uses, properties and impacts. Extended report
Plastics used in agriculture and for food: uses, properties and impacts. Extended report Open
View article: Addressing Microplastic Pollution via the Global Plastic Treaty
Addressing Microplastic Pollution via the Global Plastic Treaty Open
This policy brief addresses the issue of microplastic pollution and highlights the need for global policy interventions to reduce microplastic emissions and safeguard ecosystems and public health.
View article: Plastiques utilisés en agriculture et pour l'alimentation : usages, propriétés et impacts. Résumé du rapport de l'expertise scientifique collective
Plastiques utilisés en agriculture et pour l'alimentation : usages, propriétés et impacts. Résumé du rapport de l'expertise scientifique collective Open
View article: <i>Lactococcus lactis</i> <scp>CNCM</scp> I‐5388 versus <scp>NCDO2118</scp> by its <scp>GABA</scp> hyperproduction ability, counteracts faster stress‐induced intestinal hypersensitivity in rats
<i>Lactococcus lactis</i> <span>CNCM</span> I‐5388 versus <span>NCDO2118</span> by its <span>GABA</span> hyperproduction ability, counteracts faster stress‐induced intestinal hypersensitivity in rats Open
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by its main symptom, visceral hypersensitivity (VH), which is aggravated by stress. Gut–brain interactions and gut bacteria may alleviate IBS symptoms, …
View article: Natural diversity of lactococci in γ-aminobutyric acid (GABA) production and genetic and phenotypic determinants
Natural diversity of lactococci in γ-aminobutyric acid (GABA) production and genetic and phenotypic determinants Open
Background γ-aminobutyric acid (GABA) is a bioactive compound produced by lactic acid bacteria (LAB). The diversity of GABA production in the Lactococcus genus is poorly understood. Genotypic and phenotypic approaches were therefore combin…
View article: Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry Open
View article: Lipidomic Profiling of PFOA-Exposed Mouse Liver by Multi-Modal Mass Spectrometry Analysis
Lipidomic Profiling of PFOA-Exposed Mouse Liver by Multi-Modal Mass Spectrometry Analysis Open
Perfluorooctanoic acid (PFOA) is a synthetic perfluorinated chemical classified as a persistent organic pollutant. PFOA has been linked to many toxic effects, including liver injury. Many studies report that PFOA exposure alters serum and …
View article: <i>O</i>-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases
<i>O</i>-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases Open
Inflammatory bowel diseases (IBD) are modern diseases, with incidence rising around the world. They are associated with perturbation of the intestinal microbiota, and with alteration and crossing of the mucus barrier by the commensal bacte…
View article: Exposure to polyethylene microplastics alters immature gut microbiome in an infant in vitro gut model
Exposure to polyethylene microplastics alters immature gut microbiome in an infant in vitro gut model Open
View article: A child is not an adult: development of a new in vitro model of the toddler colon
A child is not an adult: development of a new in vitro model of the toddler colon Open
View article: Microplastics: What happens in the human digestive tract? First evidences in adults using in vitro gut models
Microplastics: What happens in the human digestive tract? First evidences in adults using in vitro gut models Open
View article: Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract
Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract Open
Gut disorders associated to irritable bowel syndrome (IBS) are combined with anxiety and depression. Evidence suggests that microbially produced neuroactive molecules, like γ-aminobutyric acid (GABA), can modulate the gut-brain axis. Two n…
View article: Author response: Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract
Author response: Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract Open
View article: Exposure to Polyethylene Microplastics Alters Immature Gut Microbiome in an Infant in Vitro Gut Model
Exposure to Polyethylene Microplastics Alters Immature Gut Microbiome in an Infant in Vitro Gut Model Open
View article: Modulation of hepatic xenobiotic metabolizing enzymes following chronic low-dose exposure to PFOA in mice
Modulation of hepatic xenobiotic metabolizing enzymes following chronic low-dose exposure to PFOA in mice Open
Meeting abstract56th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology of the Next Generation, 27septembre-1er octobre 2021
View article: In vitro models of gut digestion across childhood: current developments, challenges and future trends
In vitro models of gut digestion across childhood: current developments, challenges and future trends Open
View article: Microplastics in the human digestive environment: A focus on the potential and challenges facing in vitro gut model development
Microplastics in the human digestive environment: A focus on the potential and challenges facing in vitro gut model development Open
View article: Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses
Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses Open
View article: Structure and biological activities of a hexosamine-rich cell wall polysaccharide isolated from the probiotic Lactobacillus farciminis
Structure and biological activities of a hexosamine-rich cell wall polysaccharide isolated from the probiotic Lactobacillus farciminis Open
View article: Food-grade TiO2 is trapped by intestinal mucus in vitro but does not impair mucin O-glycosylation and short-chain fatty acid synthesis in vivo: implications for gut barrier protection
Food-grade TiO2 is trapped by intestinal mucus in vitro but does not impair mucin O-glycosylation and short-chain fatty acid synthesis in vivo: implications for gut barrier protection Open
Food-grade TiO2 is trapped by intestinal mucus in vitro but does not affect mucin O-glycosylation and short-chain fatty acid synthesis in vivo, suggesting the absence of a mucus barrier impairment under "healthy gut" conditions.
View article: Mucus: An Underestimated Gut Target for Environmental Pollutants and Food Additives
Mucus: An Underestimated Gut Target for Environmental Pollutants and Food Additives Open
Synthetic chemicals (environmental pollutants, food additives) are widely used for many industrial purposes and consumer-related applications, which implies, through manufactured products, diet, and environment, a repeated exposure of the …
View article: A Sensitive and Rapid Method to Determine the Adhesion Capacity of Probiotics and Pathogenic Microorganisms to Human Gastrointestinal Mucins
A Sensitive and Rapid Method to Determine the Adhesion Capacity of Probiotics and Pathogenic Microorganisms to Human Gastrointestinal Mucins Open
Mucus is the habitat for the microorganisms, bacteria and yeast that form the commensal flora. Mucins, the main macromolecules of mucus, and more specifically, the glycans that cover them, play essential roles in microbial gastrointestinal…