F. Xavier Gómez‐Olivé
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View article: Poor sleep health is associated with worse cardiometabolic risk among rural and urban schooled Nigerian adolescents
Poor sleep health is associated with worse cardiometabolic risk among rural and urban schooled Nigerian adolescents Open
There is limited evidence on the association between sleep health and cardio-metabolic risk (CMR) in Sub-Saharan African adolescents. Using a cross-sectional design, we assessed the association between sleep health and CMR, including 900 a…
View article: Concern for severe COVID-19 disease during the initial two years of pandemic in a rural South African community: A population-based study
Concern for severe COVID-19 disease during the initial two years of pandemic in a rural South African community: A population-based study Open
Background Globally, as of December 2023, over 700 million cases of COVID-19 were confirmed since the initial outbreak late in 2019, claiming around 7 million lives and fuelling widespread fear and anxiety. However, prospective patient-dat…
View article: Leveraging data science to understand and address multimorbidity in sub-Saharan Africa: the MADIVA protocol
Leveraging data science to understand and address multimorbidity in sub-Saharan Africa: the MADIVA protocol Open
Introduction Multimorbidity (MM), defined as two or more chronic diseases in an individual, is linked to adverse outcomes. MM is increasing in sub-Saharan Africa due to rapidly advancing epidemiological and social transitions. The Multimor…
View article: Trajectories and predictors of HIV care retention among individuals receiving ART in rural South Africa: a group-based trajectory modelling analysis
Trajectories and predictors of HIV care retention among individuals receiving ART in rural South Africa: a group-based trajectory modelling analysis Open
Five distinct retention trajectories were observed and associated with specific sociodemographic factors. Our study offers a data-driven approach to inform the design of targeted interventions to improve HIV care retention. Interventions a…
View article: A map of blood regulatory variation in South Africans enables GWAS interpretation
A map of blood regulatory variation in South Africans enables GWAS interpretation Open
Functional genomics resources are critical for interpreting human genetic studies, but currently they are predominantly from European-ancestry individuals. Here we present the South African Blood Regulatory (SABR) resource, a map of blood …
View article: Deterioration of sleep and mental health in individuals with insomnia during South Africa’s COVID-19 lockdown
Deterioration of sleep and mental health in individuals with insomnia during South Africa’s COVID-19 lockdown Open
Sleep and mental health difficulties have been observed in response to COVID-19 pandemic-induced lockdowns, but few studies have described the impact of lockdown on individuals with self-reported insomnia. The purpose of this study was to …
View article: Viral load dynamics among adults receiving HIV care in rural North-Eastern South Africa, 2015–2020: insights from a population-based record linkage study
Viral load dynamics among adults receiving HIV care in rural North-Eastern South Africa, 2015–2020: insights from a population-based record linkage study Open
Introduction The Joint United Nations Programme on HIV/AIDS set ambitious-but-reachable targets to have 95% of HIV-positive people diagnosed, 95% on ART, and 95% virally suppressed by 2030. To address the latter, post-2016, South Africa’s …
View article: Self-reported HIV testing and treatment among migrants from northeast South Africa: A cross-sectional, population-based analysis
Self-reported HIV testing and treatment among migrants from northeast South Africa: A cross-sectional, population-based analysis Open
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View article: Physical activity profile of hypertensive adults living in rural South Africa
Physical activity profile of hypertensive adults living in rural South Africa Open
Background: Understanding the physical activity behaviours of adults at risk of poor health is important to inform targeted interventions. We profiled the frequency, intensity, duration and domain (work or non-work) of self-reported physic…
View article: Examining the relationship between physical and sexual violence and psychosocial health in young people living with HIV in rural South Africa
Examining the relationship between physical and sexual violence and psychosocial health in young people living with HIV in rural South Africa Open
INTRODUCTION: Experiences of violence during youth contravene young people's rights and increase the risk of depression and poor human immunodeficiency virus (HIV) care outcomes among youth living with HIV (YLWH). Intervention targets for …
View article: Shifting gender norms to improve HIV service uptake: Qualitative findings from a large-scale community mobilization intervention in rural South Africa
Shifting gender norms to improve HIV service uptake: Qualitative findings from a large-scale community mobilization intervention in rural South Africa Open
BACKGROUND: Interventions to improve HIV service uptake are increasingly addressing inequitable and restrictive gender norms. Yet comparatively little is known about which gender norms are most salient for HIV testing and treatment and how…
View article: Perceptions about chronic health conditions, multimorbidity and self-management practices in rural northeast South Africa: findings from a qualitative study
Perceptions about chronic health conditions, multimorbidity and self-management practices in rural northeast South Africa: findings from a qualitative study Open
Introduction Chronic health conditions are the leading causes of morbidity and mortality worldwide, with a disproportionately high burden in low-income and middle-income countries. The burden arising from these conditions presents immense …
View article: The roles of pre-season immunity, age, viral shedding, and community exposures in shaping influenza household transmission dynamics
The roles of pre-season immunity, age, viral shedding, and community exposures in shaping influenza household transmission dynamics Open
Our understanding of influenza transmission remains imperfect due to the high prevalence of asymptomatic infections that often go undetected. To address this challenge, we leveraged uniquely resolved data from a household cohort study span…
View article: The prevalence, incidence, and sociodemographic risk factors of HIV among older adults in sub-Saharan Africa (AWI-Gen): a multicentre, longitudinal cohort study
The prevalence, incidence, and sociodemographic risk factors of HIV among older adults in sub-Saharan Africa (AWI-Gen): a multicentre, longitudinal cohort study Open
National Human Genome Research Institute, the National Institute of Environmental Health Sciences of the US National Institutes of Health, and the Department of Science and Innovation, South Africa.
View article: Changes in the provision and utilisation of health care services for chronic health conditions during the COVID-19 pandemic in rural northeast South Africa: an interrupted time series analysis
Changes in the provision and utilisation of health care services for chronic health conditions during the COVID-19 pandemic in rural northeast South Africa: an interrupted time series analysis Open
Although the increased adoption of the CCMDD programme can in part account for decreased medication collection visits which persisted well after lockdown measures were lifted, marked reductions in the number of newly diagnosed cases of hyp…
View article: Stress-responsive biomarkers and sexual behaviors among young women in rural South Africa
Stress-responsive biomarkers and sexual behaviors among young women in rural South Africa Open
Background Adolescence is a critical period when youth develop their decision-making skills and may engage in their first sexual encounters. Stress during this time can affect decision making; however, limited research has examined the rel…
View article: Intensity of care and the health status of caregivers to elderly rural South Africans
Intensity of care and the health status of caregivers to elderly rural South Africans Open
Objectives Informal caregivers play an indispensable role in and are often the sole source of care for older adults in low and middle-income settings worldwide. Intensive informal care predicts mortality and morbidity among caregivers in h…