Xavier Serfaty
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View article: Structural profiles of the full phagocyte NADPH oxidase unveiled by combining computational biology and experimental knowledge
Structural profiles of the full phagocyte NADPH oxidase unveiled by combining computational biology and experimental knowledge Open
View article: Combining computational biology and experimental knowledge to draw a structural profile of the active membrane-assembled NADPH oxidase complex
Combining computational biology and experimental knowledge to draw a structural profile of the active membrane-assembled NADPH oxidase complex Open
The phagocyte NADPH oxidase complex (NOX2) is activated by various intracellular stimuli, resulting in the generation of reactive oxygen species, which are responsible for many physiological processes, including innate immune defense. Stru…
View article: Role of the phospholipid binding sites, PX of p47phox and PB region of Rac1, in the formation of the phagocyte NADPH oxidase complex NOX2
Role of the phospholipid binding sites, PX of p47phox and PB region of Rac1, in the formation of the phagocyte NADPH oxidase complex NOX2 Open
View article: Splice variants of protein disulfide isomerase - identification, distribution and functional characterization in the rat
Splice variants of protein disulfide isomerase - identification, distribution and functional characterization in the rat Open
View article: Biomarkers Potency to Monitor Non-target Fauna Poisoning by Anticoagulant Rodenticides
Biomarkers Potency to Monitor Non-target Fauna Poisoning by Anticoagulant Rodenticides Open
The widespread use of pesticides to control agricultural pests is a hot topic on the public scene of environmental health. Selective pest control for minimum environmental impact is a major goal of the environmental toxicology field, notab…
View article: Impacts of vesicular environment on Nox2 activity measurements in vitro
Impacts of vesicular environment on Nox2 activity measurements in vitro Open
View article: Neutrophil NADPH oxidase enzyme (NOX2) activity measurements in compartmented system and development of giant proteoliposomes for the concerted study of its assembly and its function
Neutrophil NADPH oxidase enzyme (NOX2) activity measurements in compartmented system and development of giant proteoliposomes for the concerted study of its assembly and its function Open
La métalloenzyme multimérique membranaire NADPH oxydase du neutrophile (NOX2), est impliquée dans plusieurs fonctions physiologiques vitales incluant la réponse immunitaire, en contribuant fortement à la destruction des pathogènes ou autre…
View article: Mesures de l'activité de l'enzyme NADPH oxydase du neutrophile (NOX2) en système compartimenté et mise au point de protéoliposomes géants pour l'étude concertée de son assemblage et de sa fonction
Mesures de l'activité de l'enzyme NADPH oxydase du neutrophile (NOX2) en système compartimenté et mise au point de protéoliposomes géants pour l'étude concertée de son assemblage et de sa fonction Open
The membrane multimeric metalloenzyme NADPH oxidase (NOX2) from neutrophil is implied in several essential physiological functions including the immune response, by strongly contributing to the destruction of pathogens or other invaders of…
View article: Exploring the arachidonic acid‐induced structural changes in phagocyte NADPH oxidase p47<sup><i>phox</i></sup> and p67<sup><i>phox</i></sup> via thiol accessibility and SRCD spectroscopy
Exploring the arachidonic acid‐induced structural changes in phagocyte NADPH oxidase p47<sup><i>phox</i></sup> and p67<sup><i>phox</i></sup> via thiol accessibility and SRCD spectroscopy Open
The NADPH oxidase is the sole enzymatic complex that produces, in a controlled way, superoxide anions. In phagocytes, it is constituted by the assembly of four cytosolic (p67 phox , p47 phox , p40 phox and Rac) and two membrane (p22 phox a…