XiaHuan Gao
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View article: Metformin Ameliorates Synaptic Defects in a Mouse Model of AD by Inhibiting Cdk5 Activity
Metformin Ameliorates Synaptic Defects in a Mouse Model of AD by Inhibiting Cdk5 Activity Open
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is activated by the neuron-specific activators p35/p39 and plays important roles in neuronal development, synaptic plasticity, and cognitive behavior. However, the proteoly…
View article: The physiological modulation by intracellular kinases of hippocampal γ-oscillation in vitro
The physiological modulation by intracellular kinases of hippocampal γ-oscillation in vitro Open
Hippocampal network oscillations at gamma frequency band (γ-oscillation, 20–80 Hz) are synchronized synaptic activities generated by the interactions between the excitatory and inhibitory interneurons and are associated with higher brain f…