Junfeng Zhao
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View article: PFL-IDGAN:Personalized Federated Learning Framework Based on Interactive Dual Generative Adversarial Networks
PFL-IDGAN:Personalized Federated Learning Framework Based on Interactive Dual Generative Adversarial Networks Open
Federated learning (FL) enables collaborative model training without direct data exchange, promoting privacy-preserving data utilization. To address performance degradation caused by non-independent and identically distributed (non-IID) da…
View article: Application of geological and shortwave infrared (SWIR) spectroscopy mapping in the Yechangping giant porphyry-skarn Mo-W deposit, East Qinling, China
Application of geological and shortwave infrared (SWIR) spectroscopy mapping in the Yechangping giant porphyry-skarn Mo-W deposit, East Qinling, China Open
View article: Preparation, characterization, <i>in vitro</i> digestion properties and antioxidant activity of ginger polysaccharide nano‐selenium
Preparation, characterization, <i>in vitro</i> digestion properties and antioxidant activity of ginger polysaccharide nano‐selenium Open
BACKGROUND In order to improve the stability of nano‐selenium, ginger polysaccharide (GP) was employed as both a stabilizer and modifier to develop ginger polysaccharide nano‐selenium (GP‐SeNPs). Subsequently, the in vitro digestion charac…
View article: Treatment Options after Progression of First-Line Immunotherapy in Patients with Advanced Non-Small Cell Lung Cancer: A Systematic Review, Meta-Analysis, and Network Meta-Analysis
Treatment Options after Progression of First-Line Immunotherapy in Patients with Advanced Non-Small Cell Lung Cancer: A Systematic Review, Meta-Analysis, and Network Meta-Analysis Open
View article: Protofedgan: A Novel Federated Learning Framework for Training Generative Adversarial Networks Via Dynamic Dual-Prototype Alignment
Protofedgan: A Novel Federated Learning Framework for Training Generative Adversarial Networks Via Dynamic Dual-Prototype Alignment Open
View article: Adjuvant treatment after neoadjuvant immunotherapy in patients with non-small cell lung cancer
Adjuvant treatment after neoadjuvant immunotherapy in patients with non-small cell lung cancer Open
View article: Treatment options for tumor progression after initial immunotherapy in advanced non-small cell lung cancer: A real-world study
Treatment options for tumor progression after initial immunotherapy in advanced non-small cell lung cancer: A real-world study Open
View article: Peptide and Protein Cysteine Modification Enabled by Hydrosulfuration of Ynamide
Peptide and Protein Cysteine Modification Enabled by Hydrosulfuration of Ynamide Open
Efficient functionalization of peptides and proteins has widespread applications in chemical biology and drug discovery. However, the chemoselective and site-selective modification of proteins remains a daunting task. Herein, a highly effi…
View article: Ynamide Coupling Reagents: Origin and Advances
Ynamide Coupling Reagents: Origin and Advances Open
Since the pioneering work of Curtius and Fischer, chemical peptide synthesis has witnessed a century's development and evolved into a routine technology. However, it is far from perfect. In particular, it is challenged by sustainable devel…
View article: Peptide Synthesis Using Unprotected Amino Acids
Peptide Synthesis Using Unprotected Amino Acids Open
The mandatory use of Nα-protecting group for amino acids, which invokes protection and deprotection operations and imposes a significant negative effect on environment sustainable development, constitutes the essential principle of peptide…
View article: Peptide and Protein Cysteine Modification by Virtue of Highly Chemo-, Regio- and Stereoselective Hydrosulfuration of Ynamide
Peptide and Protein Cysteine Modification by Virtue of Highly Chemo-, Regio- and Stereoselective Hydrosulfuration of Ynamide Open
Chemoselective modification of peptides and proteins has wide applications in chemical biology and pharmaceutical development. A highly efficient chemo-, regio- and stereoselective hydrosulfuration of ynamide was developed and identified a…
View article: Transcriptome Analysis of Viable but Non-Culturable Brettanomyces bruxellensis Induced by Hop Bitter Acids
Transcriptome Analysis of Viable but Non-Culturable Brettanomyces bruxellensis Induced by Hop Bitter Acids Open
The viable but non-culturable (VBNC) state has been studied in detail in bacteria. However, it has received much less attention in eukaryotic cells. The induction of a VBNC beer-spoilage yeast ( Brettanomyces bruxellensis ) by hop bitter a…
View article: Recent Advances in Chemical Protein Modification via Cysteine
Recent Advances in Chemical Protein Modification via Cysteine Open
Proteins are the most abundant biomolecules in nature and are involved almost in all living processes.Chemical modification of proteins is an efficient strategy to mediate and study the physical and chemical properties and biological funct…
View article: Recent Advances in the Synthesis of Ynamides
Recent Advances in the Synthesis of Ynamides Open
Ynamides are a class of special ynamines bearing an electron-withdrawing group on the nitrogen atom.The electron-withdrawing group endows ynamides an optimal balance between the stability and activity, and thus enabling ynamides to be vers…
View article: Highly Chemo-, Regio- and Stereoselective Cysteine Modification of Peptides and Proteins with Ynamides
Highly Chemo-, Regio- and Stereoselective Cysteine Modification of Peptides and Proteins with Ynamides Open
Chemoselective modification of peptides and proteins has wide applications in chemical biology and pharmaceutical development. An efficient cysteine (Cys) precise modification protocol via rationally designed β-addition of ynamides is repo…
View article: Ynamide Protonation-Initiated <i>Cis</i> -Selective Polyene Cyclization and Reaction Mechanism
Ynamide Protonation-Initiated <i>Cis</i> -Selective Polyene Cyclization and Reaction Mechanism Open
Open AccessCCS ChemistryRESEARCH ARTICLE5 Sep 2022Ynamide Protonation-Initiated Cis-Selective Polyene Cyclization and Reaction Mechanism Jiasheng Yao†, Chen-Long Li†, Xing Fan, Zhou Wang, Zhi-Xiang Yu and Junfeng Zhao Jiasheng Yao† School …
View article: Complete mitochondrial genome of the Small-Branded Swift: <i>Pelopidas mathias</i> (Lepidoptera, Hesperiidae)
Complete mitochondrial genome of the Small-Branded Swift: <i>Pelopidas mathias</i> (Lepidoptera, Hesperiidae) Open
We report the complete mitochondrial genome of the Small-Branded Swift: Pelopidas mathias, which is an important pest of rice. The total length of the circular double-stranded mitogenome is 15,524 bp, containing 13 protein-coding ge…
View article: Recent Advances in Ynamide Coupling Reagent
Recent Advances in Ynamide Coupling Reagent Open
Coupling or condensation reagents are compounds that can be used to promote the direct condensation of carboxylic acids with amines or alcohols to furnish amide or ester bond, respectively.Since their discovery, coupling reagents have been…
View article: High-Throughput Metabolomics Method for Discovering Metabolic Biomarkers and Pathways to Reveal Effects and Molecular Mechanism of Ethanol Extract From Epimedium Against Osteoporosis
High-Throughput Metabolomics Method for Discovering Metabolic Biomarkers and Pathways to Reveal Effects and Molecular Mechanism of Ethanol Extract From Epimedium Against Osteoporosis Open
Metabolomics is an effective strategy to explore the molecular mechanism of herbal medicine. Epimedium, a traditional Chinese herb from the Epimedium brevicornu Maxim., has a therapeutic effect on osteoporosis (OP), however the molecular m…
View article: Genome Mining and Biosynthesis Study of a Type B Linaridin Reveals a Highly Versatile α- <i>N</i> -Methyltransferase
Genome Mining and Biosynthesis Study of a Type B Linaridin Reveals a Highly Versatile α- <i>N</i> -Methyltransferase Open
Open AccessCCS ChemistryRESEARCH ARTICLE1 Mar 2021Genome Mining and Biosynthesis Study of a Type B Linaridin Reveals a Highly Versatile α-N-Methyltransferase Fangting Wang†, Wanqing Wei†, Junfeng Zhao, Tianlu Mo, Xin Wang, Xuedong Huang, S…
View article: CCDC 1870931: Experimental Crystal Structure Determination
CCDC 1870931: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: One-way fluid-solid coupling analysis of subsurface safety valve plate
One-way fluid-solid coupling analysis of subsurface safety valve plate Open
When the working stratum pressure of the subsurface safety valve is large, the fluid in the well will have a greater impact on the valve plate, and even directly determine the opening resistance of the subsurface safety valve plate.By flui…
View article: Differential proteomics research of Bacillus amyloliquefaciens and its genome-shuffled saltant for improving fengycin production
Differential proteomics research of Bacillus amyloliquefaciens and its genome-shuffled saltant for improving fengycin production Open
View article: CCDC 1577402: Experimental Crystal Structure Determination
CCDC 1577402: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1840556: Experimental Crystal Structure Determination
CCDC 1840556: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: The theoretical chemical calculations clarify the mechanism of beta-alkylation of 1-phenylethanol with benzyl alcohol catalyzed by iron(<scp>ii</scp>) acetylacetonate methods
The theoretical chemical calculations clarify the mechanism of beta-alkylation of 1-phenylethanol with benzyl alcohol catalyzed by iron(<span>ii</span>) acetylacetonate methods Open
Iron(ii) acetylacetonate was suggested to be a better catalyst of the β-alkylation of 1-phenylethanol with benzyl alcohol to form 1,3-diphenyl-1-propanol.
View article: Reduced acetaldehyde production by genome shuffling of an industrial brewing yeast strain
Reduced acetaldehyde production by genome shuffling of an industrial brewing yeast strain Open
High levels of acetaldehyde produced by yeast during fermentation can be of concern to product quality. A novel approach, based on genome shuffling, was applied to reduce the production of acetaldehyde by industrial brewing strain YS86. Fo…
View article: Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ
Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ Open
View article: Innentitelbild: The Catalytic Mechanism of the Class C Radical <i>S</i>‐Adenosylmethionine Methyltransferase NosN (Angew. Chem. 14/2017)
Innentitelbild: The Catalytic Mechanism of the Class C Radical <i>S</i>‐Adenosylmethionine Methyltransferase NosN (Angew. Chem. 14/2017) Open
Ein kräftiges Methylierungsmittel:Im Unterschied zu allen anderen bekannten S-Adenosylmethionin(SAM)-abhängigen Methyltransferasen produziert das Enzym NosN nicht S-Adenosylhomocystein (SAH) als Koppelprodukt, wie Q. Zhang und Mitarbeiter …
View article: Palladium catalyzed Suzuki cross-coupling of benzyltrimethylammonium salts <i>via</i> C–N bond cleavage
Palladium catalyzed Suzuki cross-coupling of benzyltrimethylammonium salts <i>via</i> C–N bond cleavage Open
A Pd catalyzed Suzuki cross-coupling of a benzyltrimethylammonium salt is described. This reaction offers a highly efficient approach to diarylmethanes and also paves the way for the application of benzyltrimethylammonium salts in Pd catal…